Metabolomics in newborns with intrauterine growth retardation (IUGR): urine reveals markers of metabolic syndrome

References

• Committee on Practice Bulletins--Gynecology, American College of Obstetricians and Gynecologists, Washington, DC 20090-6920, USA. Intrauterine growth restriction. Clinical management guidelines for obstetrician-gynecologists. American College of Obstetricians and Gynecologists. Int J Gynaecol Obstet 2001;72:85–96.
   PubMedGoogle Scholar
• Diderholm B. Perinatal energy metabolism with reference to IUGR & SGA: Studies in pregnant women & newborn infants. Indian J Med Res 2009;130:612–617.
   PubMed Web of Science ®Google Scholar
• Pallotto EK, Kilbride HW. Perinatal outcome and later implications of intrauterine growth restriction. Clin Obstet Gynecol 2006;49:257–269.
   PubMed Web of Science ®Google Scholar
• Harding JE. The nutritional basis of the foetal origin of adult disease. Int J Epidemiol 2001;30:15–23.
   PubMed Web of Science ®Google Scholar
• Barker DJ, Osmond C. Infant mortality, childhood nutrition and ischaemic heart disease in England and Wales. Lancet 1986;1:1077–1081.
   PubMed Web of Science ®Google Scholar
• Newsome CA, Shiell AW, Fall CH, Phillips DI, Shier R, Law CM. Is birth weight related to later glucose and insulin metabolism? A systematic review. Diabet Med 2003;20:339–348.
   PubMed Web of Science ®Google Scholar
• Beringue F, Blondeau B, Castellotti MC, Breant B, Czernichow P, Polak M. Endocrine pancreas development in growth-retarded human foetuses. Diabetes 2002;51:385–391.
   PubMed Web of Science ®Google Scholar
• Veening MA Glucose tolerance, insulin sensitivity and insulin secretion in children born small for gestational age. J Clin Endocrinol Metab 2002;87:4657.
   PubMed Web of Science ®Google Scholar
• Hales CN, Barker DJ. Type 2 (non-insulin-dependent) diabetes mellitus: The thrifty phenotype hypothesis. Diabetologia 1992;35:595–601.
   PubMed Web of Science ®Google Scholar
• Dunger DB, Ong KK. Babies born small for gestational age: insulin sensitivity and growth hormone treatment. Horm Res 2005;64:58–65.
   PubMedGoogle Scholar
• Liguori A, Puglianiello A, Germani D, Deodati A, Peschiaroli E, Cianfarani S. Epigenetic changes predisposing to type 2 diabetes in intrauterine growth retardation. Front Endocrinol 2010; doi:10.3389/fendo.2010.00005.
   PubMedGoogle Scholar
• Cottrell EC, Seckl JR. Prenatal stress, glucocorticoids and the programming of adult disease. Front Behav Neurosci 2009;3:19.
   PubMed Web of Science ®Google Scholar
• Goland RS, Jozak S, Warren WB, Conwell IM, Stark RI, Tropper PJ. Elevated levels of umbilical cord plasma corticotropin releasing hormone in growth-retarded fetuses. J Clin Endocrinol Metab 1993;77:1174–1179.
   PubMed Web of Science ®Google Scholar
• Nyirenda MJ, Lindsay RS, Kenyon CJ, Burchell A, Seckl JR. Glucocorticoid exposure in late gestation permanently programs rat hepatic phosphoenolpyruvate carboxykinase and glucocorticoid receptor expression and causes glucose intolerance in adult offspring. J Clin Invest 1998;101:2174–2181.
   PubMed Web of Science ®Google Scholar
• Lesage J, Blondeau B, Grino M, Breant B, Dupouy JP. Maternal undernutrition during late gestation induces fetal overexposure to glucocorticoids and intrauterine growth retardation, and disturbs the hypothalamo–pituitary adrenal axis in the newborn rat. Endocrinology 2001;142:1692–1702.
   PubMed Web of Science ®Google Scholar
• Nicholson JK, Connelly J, Lindon JC, Holmes E. Metabonomics: A platform for studying drug toxicity and gene function. Nat Rev Drug Discov 2002;1:153–161.
   PubMed Web of Science ®Google Scholar
• Ellis DI, Dunn WB, Griffin JL, Allwood JW, Goodacre R. Metabolic fingerprinting as a diagnostic tool. Pharmacogenomics 2007;8:1243–1266.
   PubMed Web of Science ®Google Scholar
• Coen M, Holmes E, Lindon JC, Nicholson JK. NMR-based metabolic profiling and metabonomic approaches to problems in molecular toxicology. Chem Res Toxicol 2008;21:9–27.
   PubMed Web of Science ®Google Scholar
• Agostiniani R, Mariotti P, Cataldi L, Fanos V, Sani S, Zaccaron A, Cuzzolin L. Role of renal PGE2 in the adaptation from foetal to extrauterine life in term and preterm infants. Prostaglandins Leukot Essent Fatty Acids 2002 Dec;67(6):373–7.
   PubMed Web of Science ®Google Scholar
• Florio P, Marinoni E, Di Iorio R, Bashir M, Ciotti S, Sacchi R, Bruschettini M, Lituania M, Serra G, Michetti F, Petraglia F, Gazzolo D. Urinary S100B protein concentrations are increased in intrauterine growth-retarded newborns. Pediatrics 2006;118:747–754.
   PubMed Web of Science ®Google Scholar
• Malamitsi-Puchner A, Briana DD, Boutsikou M, Kouskouni E, Hassiakos D, Gourgiotis D. Perinatal circulating visfatin levels in intrauterine growth restriction. Pediatrics 2007;119:e1314–8.
   PubMed Web of Science ®Google Scholar
• Atzori L, Antonucci R, Barberini L, Locci E, Marincola FC, Scano P, Cortesi P, Agostiniani R, Defraia R, Weljie A, Gazzolo D, Lai A, Fanos V. 1H NMR-based metabolomic analysis of urine from preterm and term neonates. Front Biosci (Elite Ed) 2011;3:1005–1012.
   PubMedGoogle Scholar
• Fanos V, Barberini L, Antonucci R, Atzori L. Metabolomics in neonatology and pediatrics. Clin Biochem 2011;44:452–454.
   PubMed Web of Science ®Google Scholar
• Nissen PM, Nebel C, Oksbjerg N, Bertram HC. Metabolomics reveals relationship between plasma inositols and birth weight: Possible markers for fetal programming of type 2 diabetes. J Biomed Biotechnol 2011; pii:378268.
   PubMedGoogle Scholar
• Kennington AS, Hill CR, Craig J, Bogardus C, Raz I, Ortmeyer HK, Hansen BC, Romero G, Larner J. Low urinary chiro-inositol excretion in non-insulin-dependent diabetes mellitus. N Engl J Med 1990;323:373–378.
   PubMed Web of Science ®Google Scholar
• Ostlund RE Jr, McGill JB, Herskowitz I, Kipnis DM, Santiago JV, Sherman WR. D-chiro-inositol metabolism in diabetes mellitus. Proc Natl Acad Sci USA 1993;90:9988–9992.
   PubMed Web of Science ®Google Scholar
• Sugita O, Uchiyama K, Yamada T, Sato T, Okada M, Takeuchi K. Reference values of serum and urine creatinine, and of creatinine clearance by a new enzymatic method. Ann Clin Biochem 1992;29:523–528.
   PubMed Web of Science ®Google Scholar
• Lam YY, Hatzinikolas G, Weir JM, Janovská A, McAinch AJ, Game P, Meikle PJ, Wittert GA. Insulin-stimulated glucose uptake and pathways regulating energy metabolism in skeletal muscle cells: The effects of subcutaneous and visceral fat, and long-chain saturated, n-3 and n-6 polyunsaturated fatty acids. Biochim Biophys Acta 2011;1811:468–475.
   PubMed Web of Science ®Google Scholar