Is fetal pain a real evidence?

References

• Cass DL. Impact of prenatal diagnosis and therapy on neonatal surgery. Semin Fetal Neonatal Med 2011;16:130–138.
   PubMedGoogle Scholar
• Menon P, Rao KL. Current status of fetal surgery. Indian J Pediatr 2005;72:433–436.
   PubMedGoogle Scholar
• Adzick NS. Fetal myelomeningocele: natural history, pathophysiology, and in-utero intervention. Semin Fetal Neonatal Med 2010;15:9–14.
   PubMed Web of Science ®Google Scholar
• Holmes N, Harrison MR, Baskin LS. Fetal surgery for posterior urethral valves: long-term postnatal outcomes. Pediatrics 2001;108:E7.
   PubMedGoogle Scholar
• Coplen DE. Prenatal intervention for hydronephrosis. J Urol 1997;157:2270–2277.
   PubMedGoogle Scholar
• Deprest JA, Nicolaides K, Gratacos E. Fetal surgery for congenital diaphragmatic hernia is back from never gone. Fetal Diagn Ther 2011;29:6–17.
   PubMedGoogle Scholar
• Deprest J, Nicolaides K, Done’ E, Lewi P, Barki G, Largen E, DeKoninck P, Sandaite I, Ville Y, Benachi A, Jani J, Amat-Roldan I, Gratacos E. Technical aspects of fetal endoscopic tracheal occlusion for congenital diaphragmatic hernia. J Pediatr Surg 2011;46:22–32.
   PubMed Web of Science ®Google Scholar
• Okado N. Onset of synapse formation in the human spinal cord. J Comp Neurol 1981;201:211–219.
   PubMed Web of Science ®Google Scholar
• Larsen WJ, Sherman LS, Potter SS, Scott WJ, ed. Human Embryology, 3rd ed. Churchill Livingstone. Philadelphia PA; 2001.
   Google Scholar
• Humphrey T. Embryology of the central nervous system: with some correlations with functional development. Ala J Med Sci 1964;1:60–64.
   PubMedGoogle Scholar
• Valman HB, Pearson JF. What the fetus feels. Br Med J 1980;280:233–234.
   PubMedGoogle Scholar
• Gleiss J., Stuttgen G. Morphological and functional development of the skin. In Stave U, ed. Physiology of the perinatal period. New York: Appleton-Century-Crofts; 1970, pp 889–906.
   Google Scholar
• Brauer PR.. Human embryology. the ultimate USMLE step 1 review Hanley & Belfus, Philadelphia PA; 2003.
   Google Scholar
• Fitzgerald M, Butcher T, Shortland P. Developmental changes in the laminar termination of A fibre cutaneous sensory afferents in the rat spinal cord dorsal horn. J Comp Neurol 1994;348:225–233.
   PubMedGoogle Scholar
• Weidenheim KM, Kress Y, Epshteyn I, Rashbaum WK, Lyman WD. Early myelination in the human fetal lumbosacral spinal cord: characterization by light and electron microscopy. J Neuropathol Exp Neurol 1992;51:142–149.
   PubMedGoogle Scholar
• Gilles FF, Shankle W, Dooling EC. Myelinated tracts: growth patterns. In Gilles FJ, Leviton A & Dooling EC, editors. The Developing Human Brain: Growth and Epidemiologic Neuropathy. Boston: John Wright; 1983. pp 117–183.
   Google Scholar
• Weidenheim KM, Bodhireddy SR, Rashbaum WK, Lyman WD. Temporal and spatial expression of major myelin proteins in the human fetal spinal cord during the second trimester. J Neuropathol Exp Neurol 1996;55:734–745.
   PubMed Web of Science ®Google Scholar
• Zecevic N, Andjelkovic A, Matthieu JM, Tosic M. Myelin basic protein immunoreactivity in the human embryonic CNS. Brain Res Dev Brain Res 1998;105:97–108.
   Google Scholar
• Fitzgerald M. Neurobiology of fetal and neonatal pain. In: Wall PD, Melzack R, editors. Textbook of Pain. London: Churchill Livingstone; 1994. pp 153.
   Google Scholar
• Charnay Y, Paulin C, Dray F, Dubois PM. Distribution of enkephalin in human fetus and infant spinal cord: an immunofluorescence study. J Comp Neurol 1984;223:415–423.
   PubMedGoogle Scholar
• Cousins MJ, Carr DB, Horlocker TT, Bridenbaugh PO: Cousin and Brindenbaugh’s Neural blockade in clinical anesthesia and management of pain. 4th edition. Lippincott Williams & Wilkins; Philadelphia, PA, 2009.
   Google Scholar
• de Graaf-Peters VB, Hadders-Algra M. Ontogeny of the human central nervous system: what is happening when? Early Hum Dev 2006;82:257–266.
   PubMed Web of Science ®Google Scholar
• Li JY, Dubois MP, Dubois PM. Ultrastructural localization of immunoreactive corticotropin, beta-lipotropin, alpha- and beta-endorphin in cells of the human fetal anterior pituitary. Cell Tissue Res 1979;204:37–51.
   PubMedGoogle Scholar
• Bystron I, Blakemore C, Rakic P. Development of the human cerebral cortex: Boulder Committee revisited. Nat Rev Neurosci 2008;9:110–122.
   PubMed Web of Science ®Google Scholar
• Kostovic I, Lukinovic N, Judas M, Bogdanovic N, Mrzljak L, Zecevic N, Kubat M. Structural basis of the developmental plasticity in the human cerebral cortex: the role of the transient subplate zone. Metab Brain Dis 1989;4:17–23.
   PubMedGoogle Scholar
• Hanganu IL, Kilb W, Luhmann HJ. Functional synaptic projections onto subplate neurons in neonatal rat somatosensory cortex. J Neurosci 2002;22:7165–7176.
   PubMed Web of Science ®Google Scholar
• Allendoerfer KL, Shatz CJ. The subplate, a transient neocortical structure: its role in the development of connections between thalamus and cortex. Annu Rev Neurosci 1994;17:185–218.
   PubMed Web of Science ®Google Scholar
• Kanold PO, Luhmann HJ. The subplate and early cortical circuits. Annu Rev Neurosci 2010;33:23–48.
   PubMedGoogle Scholar
• Kostovic I, Judas M. The development of the subplate and thalamocortical connections in the human foetal brain. Acta Pædiatr 2010;99:1119–1127.
   PubMedGoogle Scholar
• Kanold PO, Kara P, Reid RC, Shatz CJ. Role of subplate neurons in functional maturation of visual cortical columns. Science 2003;301:521–525.
   PubMed Web of Science ®Google Scholar
• Molnár Z, Blakemore C. How do thalamic axons find their way to the cortex? Trends Neurosci 1995;18:389–397.
   PubMed Web of Science ®Google Scholar
• Kostovic I, Rakic P. Developmental history of the transient subplate zone in the visual and somatosensory cortex of the macaque monkey and human brain. J Comp Neurol 1990;297:441–470.
   PubMed Web of Science ®Google Scholar
• Hevner RF. Development of connections in the human visual system during fetal mid-gestation: a DiI-tracing study. J Neuropathol Exp Neurol 2000;59:385–392.
   PubMed Web of Science ®Google Scholar
• Huang H, Zhang J, Wakana S, Zhang W, Ren T, Richards LJ, Yarowsky P, et al. White and gray matter development in human fetal, newborn and pediatric brains. Neuroimage 2006;33:27–38.
   PubMedGoogle Scholar
• Apkarian AV, Bushnell MC, Treede RD, Zubieta JK. Human brain mechanisms of pain perception and regulation in health and disease. Eur J Pain 2005;9:463–484.
   PubMed Web of Science ®Google Scholar
• Lowery CL, Hardman MP, Manning N, Hall RW, Anand KJ, Clancy B. Neurodevelopmental changes of fetal pain. Semin Perinatol 2007;31:275–282.
   PubMed Web of Science ®Google Scholar
• Kostovic I, Judas M. Transient patterns of cortical lamination during prenatal life: do they have implications for treatment? Neurosci Biobehav Rev 2007;31:1157–1168.
   PubMedGoogle Scholar
• Ayoub AE, Kostovic I. New horizons for the subplate zone and its pioneering neurons. Cereb Cortex 2009;19:1705–1707.
   PubMedGoogle Scholar
• Krmpotic’-Nemanic’ J, Kostovic’ I, Kelovic’ Z, Nemanic’ D, Mrzljak L. Development of the human fetal auditory cortex: growth of afferent fibers. Acta Anat 1983;116:69–73.
   PubMedGoogle Scholar
• Kostovic I, Rakic P. Development of prestriate visual projections in the monkey and human fetal cerebrum revealed by transient cholinesterase staining. J Neurosci 1984;4:25–42.
   PubMed Web of Science ®Google Scholar
• Kostovic I, Goldman-Rakic PS. Transient cholinesterase staining in the mediodorsal nucleus of the thalamus and its connections in the developing human and monkey brain. J Comp Neurol 1983;219:431–447.
   PubMed Web of Science ®Google Scholar
• Rakic P, Cameron RS, Komuro H. Recognition, adhesion, transmembrane signaling and cell motility in guided neuronal migration. Curr Opin Neurobiol 1994;4:63–69.
   PubMedGoogle Scholar
• Gressens P. Mechanisms and disturbances of neuronal migration. Pediatr Res 2000;48:725–730.
   PubMedGoogle Scholar
• Afif A, Bouvier R, Buenerd A, Trouillas J, Mertens P. Development of the human fetal insular cortex: study of the gyration from 13 to 28 gestational weeks. Brain Struct Funct 2007;212:335–346.
   PubMedGoogle Scholar
• Craig AD. A new view of pain as a homeostatic emotion. Trends Neurosci 2003;26:303–307.
   PubMed Web of Science ®Google Scholar
• Eyre JA, Miller S, Clowry GJ, Conway EA, Watts C. Functional corticospinal projections are established prenatally in the human foetus permitting involvement in the development of spinal motor centres. Brain 2000;123 (Pt 1):51–64.
   PubMedGoogle Scholar
• Goldman-Rakic PS. Development of cortical circuitry and cognitive function. Child Dev 1987;58:601–622.
   PubMed Web of Science ®Google Scholar
• Chugani HT. Biological basis of emotions: brain systems and brain development. Pediatrics 1998;102:1225–1229.
   PubMedGoogle Scholar
• McKinstry RC, Mathur A, Miller JH, Ozcan A, Snyder AZ, Schefft GL, Almli CR, et al. Radial organization of developing preterm human cerebral cortex revealed by non-invasive water diffusion anisotropy MRI. Cereb Cortex 2002;12:1237–1243.
   PubMedGoogle Scholar
• Denton DA, McKinley MJ, Farrell M, Egan GF. The role of primordial emotions in the evolutionary origin of consciousness. Conscious Cogn 2009;18:500–514.
   PubMed Web of Science ®Google Scholar
• Merker B. Consciousness without a cerebral cortex: a challenge for neuroscience and medicine. Behav Brain Sci 2007;30:63–81; discussion 81.
   PubMedGoogle Scholar
• Johnson MH. Subcortical face processing. Nat Rev Neurosci 2005;6:766–774.
   PubMed Web of Science ®Google Scholar
• Ohman A, Carlsson K, Lundqvist D, Ingvar M. On the unconscious subcortical origin of human fear. Physiol Behav 2007;92:180–185.
   PubMed Web of Science ®Google Scholar
• Marín-Padilla M. Developmental neuropathology and impact of perinatal brain damage. II: white matter lesions of the neocortex. J Neuropathol Exp Neurol 1997;56:219–235.
   PubMed Web of Science ®Google Scholar
• Takada K, Shiota M, Ando M, Kimura M, Inoue K. Porencephaly and hydranencephaly: a neuropathological study of four autopsy cases. Brain Dev 1989;11:51–56.
   PubMedGoogle Scholar
• Shewmon DA, Holmes GL, Byrne PA. Consciousness in congenitally decorticate children: developmental vegetative state as self-fulfilling prophecy. Dev Med Child Neurol 1999;41:364–374.
   PubMed Web of Science ®Google Scholar
• Mulckhuyse M, Theeuwes J. Unconscious attentional orienting to exogenous cues: A review of the literature. Acta Psychol (Amst) 2010;134:299–309.
   PubMed Web of Science ®Google Scholar
• Sewards TV, Sewards MA. Visual awareness due to neuronal activities in subcortical structures: a proposal. Conscious Cogn 2000;9:86–116.
   PubMed Web of Science ®Google Scholar
• Pasley BN, Mayes LC, Schultz RT. Subcortical discrimination of unperceived objects during binocular rivalry. Neuron 2004;42:163–172.
   PubMedGoogle Scholar
• Morris JS, Ohman A, Dolan RJ. A subcortical pathway to the right amygdala mediating “unseen” fear. Proc Natl Acad Sci USA 1999;96:1680–1685.
   PubMed Web of Science ®Google Scholar
• Mahieu-Caputo D, Dommergues M, Muller F, Dumez Y. [Fetal pain]. Presse Med 2000;29:663–669.
   PubMedGoogle Scholar
• Anand KJ. Fetal pain? Pain Clinical Updates. 2006;14:1–8.
   Google Scholar
• Govindan RB, Wilson JD, Preissl H, Murphy P, Lowery CL, Eswaran H. An objective assessment of fetal and neonatal auditory evoked responses. Neuroimage 2008;43:521–527.
   PubMedGoogle Scholar
• Jardri R, Pins D, Houfflin-Debarge V, Chaffiotte C, Rocourt N, Pruvo JP, Steinling M, et al. Fetal cortical activation to sound at 33 weeks of gestation: a functional MRI study. Neuroimage 2008;42:10–18.
   PubMed Web of Science ®Google Scholar
• Vanhatalo S, Kaila K. Development of neonatal EEG activity: from phenomenology to physiology. Semin Fetal Neonatal Med 2006;11:471–478.
   PubMedGoogle Scholar
• Vanhatalo S, Lauronen L. Neonatal SEP - back to bedside with basic science. Semin Fetal Neonatal Med 2006;11:464–470.
   PubMedGoogle Scholar
• Bartocci M, Bergqvist LL, Lagercrantz H, Anand KJ. Pain activates cortical areas in the preterm newborn brain. Pain 2006;122:109–117.
   PubMed Web of Science ®Google Scholar
• Slater R, Worley A, Fabrizi L, Roberts S, Meek J, Boyd S, et al. Evoked potentials generated by noxious stimulation in the human infant brain. Eur J Pain 2010;14:321–326.
   PubMed Web of Science ®Google Scholar
• Yigiter AB, Kavak ZN. Normal standards of fetal behavior assessed by four-dimensional sonography. J Matern Fetal Neonatal Med 2006;19:707–721.
   PubMed Web of Science ®Google Scholar
• Johnston CC, Stevens BJ, Franck LS, Jack A, Stremler R, Platt R. Factors explaining lack of response to heel stick in preterm newborns. J Obstet Gynecol Neonatal Nurs 1999;28:587–594.
   PubMedGoogle Scholar
• Gingras JL, Mitchell EA, Grattan KE. Fetal homologue of infant crying. Arch Dis Child Fetal Neonatal Ed 2005;90:F415–F418.
   PubMed Web of Science ®Google Scholar
• Bellieni CV, Severi F, Bocchi C, Caparelli N, Bagnoli F, Buonocore G, Petraglia F. Blink-startle reflex habituation in 30-34-week low-risk fetuses. J Perinat Med 2005;33:33–37.
   PubMedGoogle Scholar
• Visser GH, Laurini RN, de Vries JI, Bekedam DJ, Prechtl HF. Abnormal motor behaviour in anencephalic fetuses. Early Hum Dev 1985;12:173–182.
   PubMed Web of Science ®Google Scholar
• Oberlander TF, Grunau RE, Fitzgerald C, Whitfield MF. Does parenchymal brain injury affect biobehavioral pain responses in very low birth weight infants at 32 weeks’ postconceptional age? Pediatrics 2002;110:570–576.
   PubMed Web of Science ®Google Scholar
• Mellor DJ, Diesch TJ, Gunn AJ, Bennet L. The importance of ‘awareness’ for understanding fetal pain. Brain Res Brain Res Rev 2005;49:455–471.
   PubMed Web of Science ®Google Scholar
• Nijhuis JG. Fetal behavior. Neurobiol Aging 2003;24 Suppl 1:S41–6; discussion S47.
   PubMedGoogle Scholar
• Pillai M, James D. Behavioural states in normal mature human fetuses. Arch Dis Child 1990;65:39–43.
   PubMed Web of Science ®Google Scholar
• van de Pas M, Nijhuis JG, Jongsma HW. Fetal behaviour in uncomplicated pregnancies after 41 weeks of gestation. Early Hum Dev 1994;40:29–38.
   PubMed Web of Science ®Google Scholar
• Ioffe S, Jansen AH, Russell BJ, Chernick V. Sleep, wakefulness and the monosynaptic reflex in fetal and newborn lambs. Pflugers Arch 1980;388:149–157.
   PubMed Web of Science ®Google Scholar
• Crossley KJ, Nicol MB, Hurst JJ, Walker DW, Thorburn GD. Suppression of arousal by progesterone in fetal sheep. Reprod Fertil Dev 1997;9:767–773.
   PubMed Web of Science ®Google Scholar
• Jansen AH, Chernick V. Fetal breathing and development of control of breathing, J Appl. Physiol 1991;70:1431–1446.
   Google Scholar
• Nicol MB, Hirst JJ, Walker DW. Effect of pregnane steroids on electrocortical activity and somatosensory evoked potentials. Neurosci Lett 1998;253:111–114.
   PubMed Web of Science ®Google Scholar
• Nicol MB, Hirst JJ, Walker DW. Effect of finasteride on behavioural arousal and somatosensory evoked potentials in fetal sheep. Neurosci Lett 2001;306:13–16.
   PubMed Web of Science ®Google Scholar
• Rigatto H, Blanco CE, Walker DW. The response to stimulation of hindlimb nerves in fetal sheep, in utero, during the different phases of electrocortical activity. J Dev Physiol 1982;4:175–185.
   PubMedGoogle Scholar
• Ruckebusch Y. Development of sleep and wakefulness in the foetal lamb. Electroencephalogr Clin Neurophysiol 1972;32:119–128.
   PubMedGoogle Scholar
• Ruckebusch Y, Gaujoux M, Eghbali B. Sleep cycles and kinesis in the fetal lamb. Electroencephalogr Clin Europhysiol 1977;42:226–237.
   PubMedGoogle Scholar
• Szeto HH. Behavioral states and their ontogeny: animal studies. Semin Perinatol 1992;16:211–216.
   PubMed Web of Science ®Google Scholar
• Kintraia PI, Zarnadze MG, Kintraia NP, Kashakashvili IG. Development of daily rhythmicity in heart rate and locomotor activity in the human fetus. J Circadian Rhythms 2005;3:5.
   PubMedGoogle Scholar
• Stockard-Pope JE, Werner SS, Bickford RG. Atlas of neonatal electroencephalography. New York: Raven Press; 1992.
   Google Scholar
• Birnholz JC, Benacerraf BR. The development of human fetal hearing. Science 1983;222:516–518.
   PubMed Web of Science ®Google Scholar
• Zimmer EZ, Divon MY. Fetal vibroacoustic stimulation. Obstet Gynecol 1993;81:451–457.
   PubMed Web of Science ®Google Scholar
• Leader LR, Fifer WP. The potential value of habituation in the prenate. In: Lecanuet JP, editor. Fetal development: a psychobiological perspective. Hillsdale, NJ: Lawrence Erlbaum Associates Publishers; 1995. pp 83–404.
   Google Scholar
• Lee SJ, Ralston HJ, Drey EA, Partridge JC, Rosen MA. Fetal pain: a systematic multidisciplinary review of the evidence. JAMA 2005;294:947–954.
   PubMed Web of Science ®Google Scholar
• Yoneyama Y, Sawa R, Suzuki S, Shin S, Power GG, Araki T. The relationship between uterine artery Doppler velocimetry and umbilical venous adenosine levels in pregnancies complicated by preeclampsia. Am J Obstet Gynecol 1996;174:267–271.
   PubMed Web of Science ®Google Scholar
• Yoneyama Y, Suzuki S, Sawa R, Takeuchi T, Kobayashi H, Takei R, Kiyokawa Y, et al. Changes in plasma adenosine concentrations during normal pregnancy. Gynecol Obstet Invest 2000;50:145–148.
   PubMedGoogle Scholar
• Sawa R, Asakura H, Power GG. Changes in plasma adenosine during simulated birth of fetal sheep. J Appl Physiol 1991;70:1524–1528.
   PubMedGoogle Scholar
• Yoneyama Y, Suzuki S, Sawa R, Kiyokawa Y, Power GG, Araki T. Plasma adenosine levels and P-selectin expression on platelets in preeclampsia. Obstet Gynecol 2001;97:366–370.
   PubMed Web of Science ®Google Scholar
• Donaldson A, Nicolini U, Symes EK, Rodeck CH, Tannirandorn Y. Changes in concentrations of cortisol, dehydroepiandrosterone sulphate and progesterone in fetal and maternal serum during pregnancy. Clin Endocrinol (Oxf) 1991;35:447–451.
   PubMedGoogle Scholar
• Hayaishi O. Molecular genetic studies on sleep-wake regulation, with special emphasis on the prostaglandin D(2) system. J Appl Physiol 2002;92:863–868.
   PubMed Web of Science ®Google Scholar
• Peters DA. Effects of maternal stress during different gestational periods on the serotonergic system in adult rat offspring. Pharmacol Biochem Behav 1988;31:839–843.
   PubMedGoogle Scholar
• Weinstock M. Alterations induced by gestational stress in brain morphology and behaviour of the offspring. Prog Neurobiol 2001;65:427–451.
   PubMed Web of Science ®Google Scholar
• Schneider ML. Prenatal stress exposure alters postnatal behavioral expression under conditions of novelty challenge in rhesus monkey infants. Dev Psychobiol 1992;25:529–540.
   PubMed Web of Science ®Google Scholar
• Schneider ML, Clarke AS, Kraemer GW, Roughton EC, Lubach GR, Rimm-Kaufman S, Schmidt D, Ebert M. Prenatal stress alters brain biogenic amine levels in primates. Dev Psychopathol 1998;10:427–440.
   PubMedGoogle Scholar
• Rebsam A, Seif I, Gaspar P. Refinement of thalamocortical arbors and emergence of barrel domains in the primary somatosensory cortex: a study of normal and monoamine oxidase a knock-out mice. J Neurosci 2002;22:8541–8552.
   PubMedGoogle Scholar
• Cases O, Seif I, Grimsby J, Gaspar P, Chen K, Pournin S, Müller U, et al. Aggressive behavior and altered amounts of brain serotonin and norepinephrine in mice lacking MAOA. Science 1995;268:1763–1766.
   PubMed Web of Science ®Google Scholar
• Desborough JP. The stress response to trauma and surgery. Br J Anaesth 2000;85:109–117.
   PubMed Web of Science ®Google Scholar
• Grass JA. The role of epidural anesthesia and analgesia in postoperative outcome. Anesthesiol Clin North America 2000;18:407–28, viii.
   PubMedGoogle Scholar
• Marana R, Margutti F, Catalano GF, Marana E. Stress responses to endoscopic surgery. Curr Opin Obstet Gynecol 2000;12:303–307.
   PubMed Web of Science ®Google Scholar
• Engin A, Bozkurt BS, Ersoy E, Oguz M, Gökçora N. Stress hyperglycemia in minimally invasive surgery. Surg Laparosc Endosc 1998;8:435–437.
   PubMedGoogle Scholar
• Yuen PM, Mak TW, Yim SF, Ngan Kee WD, Lam CW, Rogers MS, Chang AM. Metabolic and inflammatory responses after laparoscopic and abdominal hysterectomy. Am J Obstet Gynecol 1998;179:1–5.
   PubMed Web of Science ®Google Scholar
• Akhtar K, Kamalky-asl ID, Lamb WR, Laing I, Walton L, Pearson RC, Parrott NR. Metabolic and inflammatory responses after laparoscopic and open inguinal hernia repair. Ann R Coll Surg Engl 1998;80:125–130.
   PubMed Web of Science ®Google Scholar
• Ogihara Y, Isshiki A, Kindscher JD, Goto H. Abdominal wall lift versus carbon dioxide insufflation for laparoscopic resection of ovarian tumors. J Clin Anesth 1999;11:406–412.
   PubMedGoogle Scholar
• Ura T, Higuchi H, Taoda M, Sato T. Minimum alveolar concentration of sevoflurane that blocks the adrenergic response to surgical incision in women: MACBAR. Eur J Anaesthesiol 1999;16:176–181.
   PubMedGoogle Scholar
• Fitzgerald RD, Hieber C, Schweitzer E, Luo A, Oczenski W, Lackner FX. Intraoperative catecholamine release in brain-dead organ donors is not suppressed by administration of fentanyl. Eur J Anaesthesiol 2003;20:952–956.
   PubMed Web of Science ®Google Scholar
• Lopau K, Mark J, Schramm L, Heidbreder E, Wanner C. Hormonal changes in brain death and immune activation in the donor. Transpl Int 2000;13 Suppl 1:S282–S285.
   PubMedGoogle Scholar
• Giannakoulopoulos X, Teixeira J, Fisk N, Glover V.. Human fetal and maternal noradrenaline responses to invasive procedures. Pediatr Res 1999;45:494–499.
   PubMed Web of Science ®Google Scholar
• Fisk NM, Gitau R, Teixeira JM, Giannakoulopoulos X, Cameron AD, Glover VA.. Effect of direct fetal opioid analgesia on fetal hormonal and hemodynamic stress response to intrauterine needling. Anesthesiology 2001;95:828–835.
   PubMed Web of Science ®Google Scholar
• Anand KJ, Sippell WG, Aynsley-Green A.. Randomised trial of fentanyl anaesthesia in preterm babies undergoing surgery: effects on the stress response. Lancet 1987;1:62–66.
   PubMed Web of Science ®Google Scholar
• Van de Velde M, Jani J, De Buck F, Deprest J. Fetal pain perception and pain management. Semin Fetal Neonatal Med 2006;11:232–236.
   PubMed Web of Science ®Google Scholar
• Gaiser RR, Kurth CD. Anesthetic considerations for fetal surgery. Semin Perinatol 1999;23:507–514.
   PubMed Web of Science ®Google Scholar
• Sutton LN. Fetal surgery for neural tube defects. Best Pract Res Clin Obstet Gynaecol 2008;22:175–188.
   PubMed Web of Science ®Google Scholar
• Gupta R, Kilby M, Cooper G. Fetal surgery and anaesthetic implications. Contin Educ Anaesth Crit Care Pain. 2008;8:71–75.
   Google Scholar
• Strümper D, Durieux ME, Gogarten W, Van Aken H, Hartleb K, Marcus MA. Fetal plasma concentrations after intraamniotic sufentanil in chronically instrumented pregnant sheep. Anesthesiology 2003;98:1400–6; discussion 5A.
   Google Scholar