The genetic interface between gestational diabetes and type 2 diabetes

References

• National Institute of Diabetes and Digestive and Kidney Disease-National Diabetes Statistic 2011. Available at: http://diabetes.niddk.nih.gov/DM/PUBS/statistics. Accessed 9 september 2011.
   Google Scholar
• McCarthy MI, Hattersley AT. Molecular diagnostics in monogenic and multifactorial forms of type 2 diabetes. Expert Rev Mol Diagn 2001;1:403–412.
   PubMedGoogle Scholar
• Porter JR, Barrett TG. Monogenic syndromes of abnormal glucose homeostasis: Clinical review and relevance to the understanding of the pathology of insulin resistance and β cell failure. J Med Genet 2005;42:893–902.
   PubMed Web of Science ®Google Scholar
• Tattersall RB. Mild familial diabetes with dominant inheritance. Q J Med 1974;43:339–357.
   PubMedGoogle Scholar
• Fajans SS, Bell GI, Polonsky KS. Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young. N Engl J Med 2001;345:971–980.
   PubMed Web of Science ®Google Scholar
• Hattersley AT, Beards F, Ballantyne E, Appleton M, Harvey R, Ellard S. Mutations in the glucokinase gene of the fetus result in reduced birth weight. Nat Genet 1998;19:268–270.
   PubMed Web of Science ®Google Scholar
• Stoffel M, Bell KL, Blackburn CL, Powell KL, Seo TS, Takeda J, Vionnet N, et al. Identification of glucokinase mutations in subjects with gestational diabetes mellitus. Diabetes 1993;42:937–940.
   PubMed Web of Science ®Google Scholar
• Zouali H, Vaxillaire M, Lesage S, Sun F, Velho G, Vionnet N, Chiu K, et al. Linkage analysis and molecular scanning of glucokinase gene in NIDDM families. Diabetes 1993;42:1238–1245.
   PubMed Web of Science ®Google Scholar
• Saker PJ, Hattersley AT, Barrow B, Hammersley MS, McLellan JA, Lo YM, Olds RJ, et al. High prevalence of a missense mutation of the glucokinase gene in gestational diabetic patients due to a founder-effect in a local population. Diabetologia 1996;39:1325–1328.
   PubMed Web of Science ®Google Scholar
• Chiu KC, Go RC, Aoki M, Riggs AC, Tanizawa Y, Acton RT, Bell DS, et al. Glucokinase gene in gestational diabetes mellitus: Population association study and molecular scanning. Diabetologia 1994;37:104–110.
   PubMed Web of Science ®Google Scholar
• Allan CJ, Argyropoulos G, Bowker M, Zhu J, Lin PM, Stiver K, Golichowski A, Garvey WT. Gestational diabetes mellitus and gene mutations which affect insulin secretion. Diabetes Res Clin Pract 1997;36:135–141.
   PubMed Web of Science ®Google Scholar
• Ellard S, Beards F, Allen LI, Shepherd M, Ballantyne E, Harvey R, Hattersley AT. A high prevalence of glucokinase mutations in gestational diabetic subjects selected by clinical criteria. Diabetologia 2000;43:250–253.
   PubMed Web of Science ®Google Scholar
• Kousta E, Ellard S, Allen LI, Saker PJ, Huxtable SJ, Hattersley AT, McCarthy MI. Glucokinase mutations in a phenotypically selected multiethnic group of women with a history of gestational diabetes. Diabet Med 2001;18:683–684.
   PubMed Web of Science ®Google Scholar
• Weng J, Ekelund M, Lehto M, Li H, Ekberg G, Frid A, Aberg A, et al. Screening for MODY mutations, GAD antibodies, and type 1 diabetes–associated HLA genotypes in women with gestational diabetes mellitus. Diabetes Care 2002;25:68–71.
   PubMed Web of Science ®Google Scholar
• Lukásová P, Vcelák J, Vanková M, Vejrazková D, Andelová K, Bendlová B. Screening of mutations and polymorphisms in the glucokinase gene in Czech diabetic and healthy control populations. Physiol Res 2008;57 Suppl 1:S99–108.
   PubMedGoogle Scholar
• de Las Heras J, Martínez R, Rica I, de Nanclares GP, Vela A, Castaño L; Spanish MODY group. Heterozygous glucokinase mutations and birth weight in Spanish children. Diabet Med 2010;27:608–610.
   PubMed Web of Science ®Google Scholar
• McCarthy MI. Genomics, type 2 diabetes, and obesity. N Engl J Med 2010;363:2339–2350.
   PubMed Web of Science ®Google Scholar
• Stoffers DA, Ferrer J, Clarke WL, Habener JF. Early-onset type-II diabetes mellitus (MODY4) linked to IPF1. Nat Genet 1997;17:138–139.
   PubMed Web of Science ®Google Scholar
• Velho G, Vaxillaire M, Boccio V, Charpentier G, Froguel P. Diabetes complications in NIDDM kindreds linked to the MODY3 locus on chromosome 12q. Diabetes Care 1996;19:915–919.
   PubMed Web of Science ®Google Scholar
• Yen CJ, Beamer BA, Negri C, Silver K, Brown KA, Yarnall DP, Burns DK, et al. Molecular scanning of the human peroxisome proliferator activated receptor γ (hPPAR γ) gene in diabetic Caucasians: Identification of a Pro12Ala PPAR γ 2 missense mutation. Biochem Biophys Res Commun 1997;241:270–274.
   PubMed Web of Science ®Google Scholar
• Celi FS, Shuldiner AR. The role of peroxisome proliferator-activated receptor γ in diabetes and obesity. Curr Diab Rep 2002;2:179–185.
   PubMedGoogle Scholar
• Altshuler D, Hirschhorn JN, Klannemark M, Lindgren CM, Vohl MC, Nemesh J, Lane CR, et al. The common PPARγ Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. Nat Genet 2000;26:76–80.
   PubMed Web of Science ®Google Scholar
• Gouda HN, Sagoo GS, Harding AH, Yates J, Sandhu MS, Higgins JP. The association between the peroxisome proliferator-activated receptor-γ2 (PPARG2) Pro12Ala gene variant and type 2 diabetes mellitus: A HuGE review and meta-analysis. Am J Epidemiol 2010;171:645–655.
   PubMed Web of Science ®Google Scholar
• Pappa KI, Gazouli M, Economou K, Daskalakis G, Anastasiou E, Anagnou NP, Antsaklis A. Gestational diabetes mellitus shares polymorphisms of genes associated with insulin resistance and type 2 diabetes in the Greek population. Gynecol Endocrinol 2011;27:267–272.
   PubMed Web of Science ®Google Scholar
• Tok EC, Ertunc D, Bilgin O, Erdal EM, Kaplanoglu M, Dilek S. PPAR-γ2 Pro12Ala polymorphism is associated with weight gain in women with gestational diabetes mellitus. Eur J Obstet Gynecol Reprod Biol 2006;129:25–30.
   PubMed Web of Science ®Google Scholar
• Beamer BA, Yen CJ, Andersen RE, Muller D, Elahi D, Cheskin LJ, Andres R, et al. Association of the Pro12Ala variant in the peroxisome proliferator-activated receptor-γ2 gene with obesity in two Caucasian populations. Diabetes 1998;47:1806–1808.
   PubMed Web of Science ®Google Scholar
• Nicklas BJ, van Rossum EF, Berman DM, Ryan AS, Dennis KE, Shuldiner AR. Genetic variation in the peroxisome proliferator-activated receptor-γ2 gene (Pro12Ala) affects metabolic responses to weight loss and subsequent weight regain. Diabetes 2001;50:2172–2176.
   PubMed Web of Science ®Google Scholar
• Grant SF, Thorleifsson G, Reynisdottir I, Benediktsson R, Manolescu A, Sainz J, Helgason A, et al. Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet 2006;38:320–323.
   PubMed Web of Science ®Google Scholar
• Damcott CM, Pollin TI, Reinhart LJ, Ott SH, Shen H, Silver KD, Mitchell BD, Shuldiner AR. Polymorphisms in the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in the Amish: Replication and evidence for a role in both insulin secretion and insulin resistance. Diabetes 2006;55:2654–2659.
   PubMed Web of Science ®Google Scholar
• Florez JC, Jablonski KA, Bayley N, Pollin TI, de Bakker PI, Shuldiner AR, Knowler WC, et al.; Diabetes Prevention Program Research Group. TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program. N Engl J Med 2006;355:241–250.
   PubMed Web of Science ®Google Scholar
• Freathy RM, Hayes MG, Urbanek M, Lowe LP, Lee H, Ackerman C, Frayling TM, et al.; HAPO Study Cooperative Research Group. Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study: Common genetic variants in GCK and TCF7L2 are associated with fasting and postchallenge glucose levels in pregnancy and with the new consensus definition of gestational diabetes mellitus from the International Association of Diabetes and Pregnancy Study Groups. Diabetes 2010;59:2682–2689.
   PubMed Web of Science ®Google Scholar
• Voight BF, Scott LJ, Steinthorsdottir V, Morris AP, Dina C, Welch RP, Zeggini E, et al.; MAGIC investigators; GIANT Consortium. Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet 2010;42:579–589.
   PubMed Web of Science ®Google Scholar
• Staiger H, Machicao F, Fritsche A, Häring HU. Pathomechanisms of type 2 diabetes genes. Endocr Rev 2009;30:557–585.
   PubMed Web of Science ®Google Scholar
• Yasuda K, Miyake K, Horikawa Y, Hara K, Osawa H, Furuta H, Hirota Y, et al. Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus. Nat Genet 2008;40:1092–1097.
   PubMed Web of Science ®Google Scholar
• Shin HD, Park BL, Shin HJ, Kim JY, Park S, Kim B, Kim SH. Association of KCNQ1 polymorphisms with the gestational diabetes mellitus in Korean women. J Clin Endocrinol Metab 2010;95:445–449.
   PubMed Web of Science ®Google Scholar
• Cho YM, Kim TH, Lim S, Choi SH, Shin HD, Lee HK, Park KS, Jang HC. Type 2 diabetes-associated genetic variants discovered in the recent genome-wide association studies are related to gestational diabetes mellitus in the Korean population. Diabetologia 2009;52:253–261.
   PubMed Web of Science ®Google Scholar
• Lauenborg J, Grarup N, Damm P, Borch-Johnsen K, Jørgensen T, Pedersen O, Hansen T. Common type 2 diabetes risk gene variants associate with gestational diabetes. J Clin Endocrinol Metab 2009;94:145–150.
   PubMed Web of Science ®Google Scholar