Association of folic acid receptor α in maternal serum with neural tube defects

References

• Tamura T, Picciano MF. Folate and human reproduction. Am J Clin Nutr 2006;83:993–1016
   PubMed Web of Science ®Google Scholar
• Giles C. An account of 335 cases of megaloblastic anaemia of pregnancy and the puerperium. J Clin Pathol 1966;19:1–11
   PubMedGoogle Scholar
• MRC Vitamin Study Research Group. Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. Lancet 1991;338:131–7
   PubMedGoogle Scholar
• Czeizel AE, Dudás I. Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation. N Engl J Med 1992;327:1832–5
   PubMed Web of Science ®Google Scholar
• Piedrahita JA, Oetama B, Bennett GD, et al. Mice lacking the folic acid-binding protein Folbp1 are defective in early embryonic development. Nat Genet 1999;23:228–32
   PubMed Web of Science ®Google Scholar
• Antony AC. Folate receptors. Annu Rev Nutr 1996;16:501–21
   PubMed Web of Science ®Google Scholar
• Finnell RH, Wlodarczyk B, Speigelstein O, et al. Folate transport abnormalities and congenital defects. In: Milstien S, Kapatos G, Levine RA, Shane B, eds. Chemistry and biology of pteridines and folates. Boston (MA): Kluwer Academic, 2002:637–42
   Google Scholar
• Kamen BA, Caston JD. Purification of folate binding factor in normal umbilical cord serum. Proc Natl Acad Sci U S A 1975;72:4261–4
   PubMedGoogle Scholar
• Bisseling TM, Steegers EA, van den Heuvel JJ, et al. Placental folate transport and binding are not impaired in pregnancies complicated by fetal growth restriction. Placenta 2004;25:588–93
   PubMedGoogle Scholar
• Solanky N, Requena Jimenez A, et al. Expression of folate transporters in human placenta and implications for homocysteine metabolism. Placenta 2010;31:134–43
   PubMed Web of Science ®Google Scholar
• Barber RC, Shaw GM, Lammer EJ, et al. Lack of association between mutations in the folate receptor-alpha gene and spina bifida. Am J Med Genet 1998;76:310–7. [Erratum, Am J Med Genet 1998;79:231]
   PubMed Web of Science ®Google Scholar
• da Costa M, Sequeira JM, Rothenberg SP, Weedon J. Antibodies to folate receptors impair embryogenesis and fetal development in the rat. Birth Defects Res A Clin Mol Teratol 2003;67:837–47
   PubMedGoogle Scholar
• Hansen DK, Streck RD, Antony AC. Antisense modulation of the coding or regulatory sequence of the folate receptor (folate binding protein-1) in mouse embryos leads to neural tube defects. Birth Defects Res A Clin Mol Teratol 2003;67:475–87
   PubMedGoogle Scholar
• Saitsu H, Ishibashi M, Nakano H, Shiota K. Spatial and temporal expression of folate-binding protein 1 (Fbp1) is closely associated with anterior neural tube closure in mice. Dev Dyn 2003;226:112–7
   PubMedGoogle Scholar
• Dansky LV, Rosenblatt DS, Andermann E. Mechanisms of teratogenesis: folic acid and antiepileptic therapy. Neurology 1992; 42:32–42
   PubMed Web of Science ®Google Scholar
• Hernández-Diaz S, Werler MM, Walker AM, Mitchell AA. Folic acid antagonists during pregnancy and the risk of birth defects. N Engl J Med 2000;343:1608–14
   PubMed Web of Science ®Google Scholar
• De Marco P, Moroni A, Merello E, et al. Folate pathway gene alterations in patients with neural tube defects. Am J Med Genet 2000;95:216–23
   PubMed Web of Science ®Google Scholar
• Rothenberg SP, da Costa MP, Sequeira JM, et al. Autoantibodies against folate receptors in women with a pregnancy complicated by a neural-tube defect. N Engl J Med 2004;350:134–42
   PubMed Web of Science ®Google Scholar
• Bliek JB, Rothenberg SP, Steegers-Theunissen RP. Maternal folate receptor autoantibodies and cleft lip and/or palate. Int J Gynaecol Obstet 2006;93:142–3
   PubMedGoogle Scholar
• Molloy AM, Quadros EV, Sequeira JM, et al. Lack of association between folate-receptor autoantibodies and neural-tube defects. N Engl J Med 2009;361:152–60
   PubMedGoogle Scholar
• Kirke PN, Molloy AM, Daly LE, et al. Maternal plasma folate and vitamin B12 are independent risk factors for neural tube defects. Q J Med 1993;86:703–8
   PubMedGoogle Scholar
• Cabrera RM, Hill DS, Etheredge AJ, Finnell RH. Investigations into the etiology of neural tube defects. Birth Defects Res. C. Embryo Today 2004;72:330–44
   PubMedGoogle Scholar
• Boyles AL, Ballard JL, Gorman EB, et al. Association between inhibited binding of folic acid to folate receptor alpha in maternal serum and folate-related birth defects in Norway. Hum Reprod 2011;26:2232–8
   PubMedGoogle Scholar
• Elnakat H, Ratnam M. Distribution, functionality and gene regulation of folate receptor isoforms: implications in targeted therapy. Adv Drug Deliv Rev 2004;56:1067–84
   PubMed Web of Science ®Google Scholar
• Kelemen LE. The role of folate receptor alpha in cancer development, progression and treatment: cause, consequence or innocent bystander? Int J Cancer 2006;119:243–50
   PubMed Web of Science ®Google Scholar