References
- Archibald RM. Methods for the determination of alloxan, together with observations of certain properties of alloxan. J Biol Chem 1945;158:347–373.
- Ashcroft SJ, Harrison DE, Poje M, Rocic B. (1986). Structure-activity relationships of alloxan-like compounds derived from uric acid. Br J Pharmacol 1986;89:469–472.
- Bilic N, Felber JP. An improved fluorometric method for measurement of alloxan in biological fluids. Anal Biochem 1969;29:91–99.
- Bromme HJ, Weinandy R, Peschke D, Peschke E. Simultaneous quantitative determination of alloxan, GSH and GSSG by HPlC. Estimation of the frequency of redox cycling between alloxan and dialuric acid. Horm Metab Res 2001;33:106–109.
- Bromme HJ, Weinandy R, Peschke E. Influence of oxygen concentration on redox cycling of alloxan and dialuric acid. Horm Metab Res 2005;37:729–733.
- Dominis M, Rocic S, Ashcroft SJ, Rocic B, Poje M. Diabetogenic action of alloxan-like compounds: cytotoxic effects of 5-hydroxy-pseudouric acid and dehydrouramil hydrate hydrochloride on rat pancreatic beta cells. Diabetologia 1984;27:403–406.
- Elsner M, Gurgul-Convey E, Lenzen S. Relation between triketone structure, generation of reactive oxygen species, and selective toxicity of the diabetogenic agent alloxan. Antioxid Redox Signal 2008;10:691–699.
- Gorus FK, Finsy R, Pipeleers DG. Alloxan toxicity in human and canine spermatozoa. Possible biochemical basis for a species difference in sensitivity. Biochem Pharmacol 1986;35:1725–1729.
- Harman AW, Fischer LJ. Alloxan toxicity in isolated rat hepatocytes and protection by sugars. Biochem Pharmacol 1982;31:3731–3736.
- Holmgren A, Lyckeborg C. Enzymatic reduction of alloxan by thioredoxin and NADPH-thioredoxin reductase. Proc Natl Acad Sci USA 1980;77:5149–5152.
- Idahl LA, Lernmark A, Sehlin J, Taljedal IB. Alloxan cytotoxicity in vitro. Inhibition of rubidium ion pumping in pancreatic beta-cells. Biochem J 1977;162:9–18.
- Islam MS, Loots DT. Experimental rodent models of type 2 diabetes: a review. Methods Find Exp Clin Pharmacol 2009;31:249–261.
- Katayama M, Taniguchi H. Products in the fluorometric reaction of purines with 4,5-dimethyl-o-phenylenediamine after oxidation using N-bromosuccinimide. Yakugaku Zasshi 1990;110:776–782.
- Larsson L, Sorbo B, Tiselius HG, Ohman S. A method for quantitative wet chemical analysis of urinary calculi. Clin Chim Acta 1984;140:9–20.
- Lenzen S. The mechanisms of alloxan- and streptozotocin-induced diabetes. Diabetologia 2008;51:216–226.
- McLetchie NG. Alloxan diabetes: the sorcerer and his apprentice. Diabetologia 1982;23:72–75.
- McLetchie NG. Alloxan diabetes: a discovery, albeit a minor one. J R Coll Physicians Edinb 2002;32:134–142.
- Nakamura U, Iwase M, Uchizono Y, Sonoki K, Sasaki N, Imoto H, Goto D, Iida M. Rapid intracellular acidification and cell death by H2O2 and alloxan in pancreatic beta cells. Free Radic Biol Med 2006;40:2047–2055.
- Poje M, Rocic B, Sikirica M, Vickovic I, Bruvo M. Oxidation of uric acid. 4. Synthesis, structure, and diabetogenic action of 5-imino-2,4,6(1H,3H,5H)-pyrimidinetrione salts and their alloxan-like covalent adducts. J Med Chem 1983;26:861–864.
- Sathishkumar K, Gao X, Raghavamenon AC, Parinandi N, Pryor WA, Uppu RM. Cholesterol secoaldehyde induces apoptosis in H9c2 cardiomyoblasts through reactive oxygen species involving mitochondrial and death receptor pathways. Free Radic Biol Med 2009;47:548–558.
- Sathishkumar K, Haque M, Perumal TE, Francis J, Uppu RM. A major ozonation product of cholesterol, 3beta-hydroxy-5-oxo-5,6-secocholestan-6-al, induces apoptosis in H9c2 cardiomyoblasts. FEBS Lett 2005;579:6444–6450.
- Seligson D, Seligson H. The conversion of alloxan to alloxanic acid in plasma. J Biol Chem 1951;190:647–657.
- Veracity D. White flour contains diabetes-causing contaminant alloxan. Natural News.Com 2005; June 02. (www.naturalnews.com/008191.html).
- Volk KJ, Yost RA, Brajter-Toth A. On-line mass spectrometric investigation of the peroxidase-catalysed oxidation of uric acid. J Pharm Biomed Anal 1990;8:205–215.
- Wang H, Chen J, Chai J. A study of mRNA expression of glucose transporter gene in rats with diabetes mellitus. Chin Med J (Engl) 1995;108:892–894.
- Winterbourn CC, Munday R. Glutathione-mediated redox cycling of alloxan. Mechanisms of superoxide dismutase inhibition and of metal-catalyzed OH. formation. Biochem Pharmacol 1989;38:271–277.
- Zhang H, Brunk UT. Alloxan cytotoxicity is highly potentiated by plasma membrane- and lysosomal-associated iron–a study on a model system of cultured J-774 cells. Diabetologia 1993;36:707–715.