101
Views
3
CrossRef citations to date
0
Altmetric
Research Article

DNA damage, p53, Ki-67 and COX-2 expression in rat tongue cells exposed to nandrolone decanoate

, , , , , , & show all
Pages 289-296 | Received 10 Oct 2012, Accepted 30 Nov 2012, Published online: 16 Jan 2013

References

  • Allouh MZ, Rosser BW. (2010). Nandrolone decanoate increases satellite cell numbers in the chicken pectoralis muscle. Histol Histopathol 25:133–40
  • Alves MJ, Dos Santos MR, Dias RG, et al. (2010). Abnormal neurovascular control in anabolic androgenic steroids users. Med Sci Sports Exerc 42:865–71
  • Atula T, Hedström J, Ristimäki A, et al. (2006). Cyclooxygenase-2 expression in squamous cell carcinoma of the oral cavity and pharynx, association to p53 and clinical outcome. Oncol Rep 16:485–90
  • Bronson FH. (1996). Effects of prolonged exposure to anabolic steroids on the behavior of male and female mice. Pharmacol Biochem Behav 53:329–34
  • Califano J, van der Riet P, Westra W, et al. (1996). Genetic progression model for head and neck cancer, implications for field cancerization. Cancer Res 56:2488–92
  • Dempke W, Rie C, Grothey A, et al. (2001). Cyclooxygenase-2, a novel target for cancer chemotherapy? J Cancer Res Clin Oncol 127:411–17
  • Dirix A, Knuttgen HE, Titell K. (1988). Olympic book of sports medicine. London: Blackwell
  • Dubois RN, Abramson SB, Crofford L, et al. (1998). Cyclooxygenase in biology and disease. FASEB J 12:1063–73
  • Egydio F, Ribeiro DA, Noguti J, et al. (2012). Influence of sleep deprivation and morphine on the expression of inducible nitric oxide synthase and cyclooxygenase-2 in skin of hairless mice. Toxicol Mech Methods 22:577--83
  • Ferreira UMG, Ferreira ACD, Azevedo AMP, et al. (2007). Esteróides anabólicos Androgênicos. Ver Bras Prom e Saúde 20:267–5 [Portuguese]
  • Fracalossi AC, Comparini L, Funabashi K, et al. (2011). Ras gene mutation is not related to tumour invasion during rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide. J Oral Pathol Med 40:325–33
  • Gentileschi P, Palmieri G, Perfetti A, et al. (2005). Anabolic steroid nandrolone augments hepatic regenerative response in rats. Transpl Proc 37:4563–6
  • Hall RCW, Hall RCW. (2005). Abuse of supraphysiologic doses of anabolic steroids. South Med J 98:550–5
  • Inoue H, Yokoyama C, Hara S, et al. (1995). Transcriptional regulation of human protaglandin-endoperoxidase-2 gene by lipopolysaccharide and phorbol ester in vascular endothelial cells. Involvement of both nuclear factor for interleukin-6 expression site and cAMP response element. J Biol Chem 270:24965–71
  • Kanayama G, Gruber AJ, Pope JR HG, et al. (2001). Over the counter drug use in gymnasiums, an underrecognized substance abuse problem? Psychother Psychosom 70:137–40
  • Kargman S, Charleson S, Cartwright M, et al. (1996). Characterization of Prostaglandin G/H Synthase 1 and 2 in rat, dog, monkey, and human gastrointestinal tracts. Gastroenterology 111:445–54
  • Kutscher EC, Lund BC, Perry PJ. (2002). Anabolic steroids, a review for the clinician. Sports Med 32:285–96
  • Limoli CL, Kaplan MI, Phillips JW, et al. (1997). Differential induction of chromosomal instability by DNA strand-breaking agents. Cancer Res 57:4048–56
  • Loro LL, Vintermyr OK, Johannessen AC. (2005). Apoptosis in normal and diseased oral tissues. Oral Dis 11:274–87
  • Minicucci EM, Ribeiro DA, da Silva GN, et al. (2011). The role of the TP53 gene during rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide. Exp Toxicol Pathol 63:483–9
  • Parssinen M, Kujala U, Vartiainen E, et al. (2000). Increased premature mortality of competitive powerlifters suspected to have used anabolic agents. Int J Sports Med 21:225–7
  • Polverini PH, Nor JE. (1999). Apoptosis and predisposition to oral cancer. Crit Rev Oral Biol Med 10:139–52
  • Pope JR, Katz DL. (1988). Affective and psychotic symptoms associated with anabolic steroids use. Am J Psychiatry 145:487–90
  • Ribeiro DA, Fávero Salvadori DM, da Silva RN, et al. (2004). Genomic instability in non-neoplastic oral mucosa cells can predict risk during 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis. Oral Oncol 40:910–15
  • Scharhag J, Urhausen A, Kindermann W. (2003). Anabolic steroid-induced echocardiographic characteristics of professional football players? J Am Coll Cardiol 42:588–9
  • Shokri S, Aitken RJ, Abdolvahhabi M, et al. (2010). Exercise and supraphysiological dose of nandrolone decanoate increase apoptosis in spermatogenic cells. Basic Clin Pharmacol Toxicol 106:324–30
  • Silva, PRP, Danielski R, Czepielewski MA. (2002) Esteróides anabolizantes no esporte. Rev Bras Med Esporte 8:1–17 [Portuguese]
  • Sjodren S, Inganas M, Norbert T. (1996). The p53 gene in breast cancer, prognostic value of complementary DNA sequencing versus immunohistochemistry. J Nat Cancer Inst 88:173–82
  • Su T, Pagliaro M, Schmidt PJ, et al. (1993). Neuropsychiatric effects of anabolic steroids in male normal volunteers. JAMA 269:2760–4
  • Tsuji M, Dubois RN. (1995). Alteration in cellular adhesion and apoptosis in epithelial cells over expressing prostaglandin endoperoxidase synthase-2. Cell 83:493–501
  • Whyte DA, Brton CE, Shillitoe EJ. (2002). The unexplained survival of cells in oral cancer: what is the role of p53? J Oral Pathol Med 31:125–33
  • Woodiwiss AJ, Trifunovic B, Philippides M, Norton GR (2000). Effects of an androgenic steroid on exercise-induced cardiac remodeling in rats. J Appl Physiol 88:409–15

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.