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Research Article

The transillumination technique as a method for the assessment of spermatogenesis using medicinal plants: the effect of extracts of black maca (Lepidium meyenii) and camu camu (Myrciaria dubia) on stages of the spermatogenic cycle in male rats

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Pages 559-565 | Received 13 Mar 2013, Accepted 21 Apr 2013, Published online: 07 Oct 2013

References

  • Akachi T, Shiina Y, Kawaguchi T, et al. (2010). 1-Methylmalate from camu-camu (Myrciaria dubia) suppresed d-galactosamine-induced liver injury in rats. Biosci Biotechnol Biochem 74:573–8
  • Almenara A, Escalante G, Gazzo E, et al. (2001). Transillumination to evaluate spermatogenesis: effect of testosterone enanthate in adult male rats. Arch Androl 46:21–7
  • Aquino R, Morelli S, Lauro MR, et al. (2001). Phenolic constituents and antioxidant activity of an extract of Anthuriumversicolor leaves. J Nat Prod 64:1019–23
  • Benedetti S, Tagliamonte MC, Catalani S, et al. (2012). Differences in blood and semen oxidative status in fertile and infertile men, and their relationship with sperm quality. Reprod Biomed Online 25:300–6
  • Bremner WJ, Millar MR, Sharpe RM, et al. (1994). Immunohistochemical localization of androgen receptors in the rat testis: evidence for stage-dependent expression and regulation by androgens. Endocrinology 135:1227–34
  • Bustos-Obregon E, Yucra S, Gonzales GF. (2005). Lepidium meyenii (Maca) reduces spermatogenic damage induced by a single dose of malathion in mice. Asian J Androl 7:71–6
  • Ceribasi AO, Türk G, Sönmez M, et al. (2010). Toxic effect of cyclophosphamide on sperm morphology, testicular histology and blood oxidant-antioxidant balance, and protective roles of lycopene and ellagic acid. Basic Clin Pharmacol Toxicol 107:730–6
  • Cobo B. (1956). Historia del Nuevo Mundo. Biblioteca de Autores Españoles. 1653. Sevilla: España, 430
  • Creasy DM. (2003). Evaluation of testicular toxicology: a synopsis and discussion of the recommendations proposed by the Society of Toxicologic Pathology. Birth Defects Res Part B Dev Reprod Toxicol 68:408–15
  • Dix DJ, Allen JW, Collins BW, et al. (1996). Targeted gene disruption of Hsp70-2 results in failed meiosis, germ cell apoptosis, and male infertility. Proc Natl Acad Sci USA 93:3264–8
  • Elkin ND, Piner JA, Sharpe RM. (2010). Toxicant-induced leakage of germ cell-specific proteins from seminiferous tubules in the rat: relationship to blood-testis barrier integrity and prospects for biomonitoring. Toxicol Sci 117:439–48
  • Farías JG, Puebla M, Acevedo A, et al. (2010). Oxidative stress in rat testis and epididymis under intermittent hypobaric hypoxia: protective role of ascorbate supplementation. J Androl 31:314–21
  • Foster WG, Maharaj-Briceño S, Cyr DG. (2011). Dioxin-induced changes in epididymal sperm count and spermatogenesis. Cien Saude Colet 16:2893–905
  • Gasco M, Aguilar J, Gonzales GF. (2007). Effect of chronic treatment with three varieties of Lepidium meyenii (Maca) on reproductive parameters and DNA quantification in adult male rats. Andrologia 39:151–8
  • Gasco M, Rubio J, Chung A, et al. (2003). Effect of high altitude exposure on spermatogenesis and epididymal sperm count in male rats. Andrologia 35:368–74
  • Gonzales C, Rubio J, Gasco M, et al. (2006a). Effect of short-term and long-term treatments with three ecotypes of Lepidium meyenii (MACA) on spermatogenesis in rats. J Ethnopharmacol 103:448–54
  • Gonzales GF, Córdova A, Vega K, et al. (2003). Effect of Lepidium meyenii (Maca), a root with aphrodisiac and fertility-enhancing properties, on serum reproductive hormone levels in adult healthy men. J Endocrinol 176:163–8
  • Gonzales GF, Del Valle L. (1995). Adult rat seminiferous tubules secrete a fraction greater than 30 kDa to regulate spermatogenesis. Hum Reprod 10:1435–43
  • Gonzales GF, Hartinger S, Flores Y, et al. (2004). Cycloheximide prevents production of arresting, a fraction of 30--50 kDa obtained from seminiferous tubule conditioned medium. Asian J Androl 6:359–64
  • Gonzales GF, Nieto J, Rubio J, et al. (2006b). Effect of black maca (Lepidium meyenii) on one spermatogenic cycle in rats. Andrologia 38:166–72
  • Gonzales GF, Risbridger GP, Pollanen P, de Kretser DM. (1989). Stage-specific inhibin secretion by rat seminiferous tubules. Reprod Fertil Dev 1:275--9
  • Gonzales GF, Ruiz A, Gonzales C, et al. (2001). Effect of Lepiidum meyenii (maca) roots on spermatogenesis of male rats. Asian J Androl 3:231–3
  • Inoue T, Komoda H, Uchida T, et al. (2008). Tropical fruit camu-camu (Myrciaria dubia) has anti-oxidative and anti-inflammatory properties. J Cardiol 52:127–32
  • Jain S, Jain A, Paliwal P, et al. (2012). Antifertility effect of chronically administered Tabernaemontana divaricata leaf extract on male rats. Asian Pac J Trop Med 5:547–51
  • Jang H, Kim SJ, Yuk SM, et al. (2012). Effects of anthocyanin extracted from black soybean seed coat on spermatogenesis in a rat varicocele-induced model. Reprod Fertil Dev 24:649–55
  • Justi KC, Visentainer JV, Evelázio de Souza N, et al. (2000). Nutritional composition and vitamin C stability in stored camu-camu (Myrciaria dubia) pulp. Arch Latinoam Nutr 50:405–8
  • Kähkönen MP, Hopia AI, Vuorela HJ, et al. (1999). Antioxidant activity of plant extracts containing phenolic compounds. J Agric Food Chem 47:3954–62
  • Kubota K, Ohsako S, Kurosawa S, et al. (2003). Effects of vinclozolin administration on sperm production and testosterone biosynthetic pathway in adult male rat. J Reprod Dev 49:403–12
  • Laurentino SS, Correia S, Cavaco JE, et al. (2012). Regucalcin, a calcium-binding protein with a role in male reproduction? Mol Hum Reprod 18:161–70
  • Leiva-Revilla J, Cárdenas-Valencia I, Rubio J, et al. (2012). Evaluation of different doses of mashua (Tropaeolum tuberosum) on the reduction of sperm production, motility and morphology in adult male rats. Andrologia 44:205–12
  • Leyva KP, Rubio J, Peralta F, et al. (2011). Effect of Punica granatum (pomegranate) on sperm production in male rats treated with lead acetate. Toxicol Mech Methods 21:495–502
  • Mäkelä JA, Saario V, Bourguiba-Hachemi S, et al. (2011). Hedgehog signalling promotes germ cell survival in the rat testis. Reproduction 142:711–21
  • Nascimento OV, Boleti AP, Yuyama LK, et al. (2013). Effects of diet supplementation with Camu camu (Myrciaria dubia HBK Mc Vaigh) fruit in a rat model of diet-induced obesity. An Acad Bras Cienc 85:355--63
  • National Research Council. (1996). Guide of the care and use of Laboratory animals. Washington DC: National Academy Press, 125
  • Parvinen M. (1982). Regulation of the seminiferous epithelium. Endocr Rev 3:404–17
  • Ranawat P, Kaushik G, Saikia UN, et al. (2013). Quercetin impairs the reproductive potential of male mice. Andrologia 45:56–65
  • Reynertson KA, Yang H, Jiang B, et al. (2008). Quantitative analysis of antiradical phenolic constituents from fourteen edible Nyrtaceae fruits. Food Chem 109:883–90
  • Rubio J, Riqueros MI, Gasco M, et al. (2006). Lepidium meyenii (Maca) reversed the lead acetate induced – damage on reproductive function in male rats. Food Chem Toxicol 44:1114–22
  • Shiva M, Gautam AK, Verma Y, et al. (2011). Association between sperm quality, oxidative stress, and seminal antioxidant activity. Clin Biochem 44:319–24
  • Suominen JS, Linderborg J, Nikula H, et al. (2003). The effects of mono-2-ethylhexyl phathalate, adriamycin and N-ethyl-N-nitrosourea on stage-specific apoptosis and DNA synthesis in the mouse spermatogenesis. Toxicol Lett 143:163–73
  • Taepongsorat L, Tangpraprutgul P, Kitana N, et al. (2008). Stimulating effects of quercetin on sperm quality and reproductive organs in adult male rats. Asian J Androl 10:249–58
  • Tajaddini S, Ebrahimi S, Behnam B, et al. (2013). Antioxidant effect of manganese on the testis structure and sperm parameters of formalin-treated mice. Andrologia. [Epub ahead of print]. doi: 10.1111/and.12069
  • Takahashi O, Oishi S. (2003). Testicular toxicity of dietarely or parentarelly administered bisphenol A in rats and mice. Food Chem Toxicol 41:1035–44
  • Tremellen K. (2008). Oxidative stress and male infertility – a clinical perspective. Hum Reprod Update 14:243–58
  • Ueda H, Kuroiwa E, Tachibana Y, et al. (2004). Aldose reductase inhibitors from the leaves of Myrciaria dubia (H.B. & K.) McVaugh. Phytomedicine 11:652–6
  • Valerio LG Jr, Gonzales GF. (2005). Toxicological aspects of the South American herbs cat's claw (Uncaria tomentosa) and Maca (Lepidium meyenii): a critical synopsis. Toxicol Rev 24:11--35
  • Vasco C, Zuccotti M, Redi CA, et al. (2009). Identification, isolation, and RT-PCR analysis of single stage-specific spermatogenetic cells obtained from portions of seminiferous tubules classified by transillumination microscopy. Mol Reprod Dev 76:1173–7
  • Yucra S, Gasco M, Rubio J, et al. (2008). Effect of different fractions from hydroalcoholic extract of Black Maca (Lepidium meyenii) on testicular function in adult male rats. Fertil Steril 89:1461–7
  • Yazama F, Furuta K, Fujimoto M, et al. (2006). Abnormal spermatogenesis in mice unable to shynthesize ascorbic acid. Anat Sci Int 81:115–25
  • Zanatta CF, Cuevas E, Bobbio FO, et al. (2005). Determination of anthocyanins from camu-camu (Myrciaria dubia) by HPLC-PDA, HPLC-MS, and NMR. J Agric Food Chem 53:9531–5
  • Zhishen J, Mengcheng T, Jianming W. (1999). Research on antioxidant activity of flavonoids from natural materials. Food Chem 64:555–9

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