126
Views
2
CrossRef citations to date
0
Altmetric
Research Article

In vitro study on the pulmonary cytotoxicity of amiodarone

, &
Pages 610-616 | Received 25 May 2013, Accepted 02 Jun 2013, Published online: 07 Oct 2013

References

  • Alsamri MT, Al Shamsi M, Al-Salam S, et al. (2011). Measurement of oxygen consumption by murine tissues in vitro. J Pharmacol Toxicol Meth 63:196–204
  • Alsamri MT, Biradar AV, Alsuwaidi AR, et al. (2012). Study on in vitro biocompatibility of calcined mesoporous silica particles with fetal blood cells. Int J Nanomed 7:3111–21
  • Alsamri MT, Silva R, Almarzooqi S, et al. (2013). Lung toxicities of core-shell-shell nanomaterials composed of carbon, cobalt and silica. Int J Nanomed 8:1223–44
  • Alsuwaidi AR, Alsamri MT, Alfazari AS, et al. (2013). Lung tissue bioenergetics and caspase activity in rodents. BMC Research Note Jan 12, 6:12. doi: 10.1186/1756-0500-6-12
  • Bedrossian CW, Warren CJ, Ohar J, Bhan R. (1997). Amiodarone pulmonary toxicity: cytopathology, ultrastructure, and immunocytochemistry. Ann Diagn Pathol 1:47–56
  • Bolt MW, Card JW, Racz WJ, et al. (2001). Disruption of mitochondrial function and cellular ATP levels by amiodarone and N-desethylamiodarone in initiation of amiodarone-induced pulmonary cytotoxicity. J Pharmacol Exp Ther 298:1280–9
  • Duarte FV, Simoes AM, Teodoro JS, et al. (2011). Exposure to dibenzofuran affects lung mitochondrial function in vitro. Toxicol Mech Methods 21:571–6
  • Dykens JA, Will Y. (2007). The significance of mitochondrial toxicity testing in drug development. Drug Discov Today 12:777–85
  • Fromenty B, Fisch C, Berson A, et al. (1990). Dual effect of amiodarone on mitochondrial respiration. Initial protonophoric uncoupling effect followed by inhibition of the respiratory chain at the levels of complex I and complex II. J Pharmacol Exp Ther 255:1377–84
  • Haffajee CI, Love JC, Canada AT, et al. (1983). Clinical pharmacokinetics and efficacy of amiodarone for refractory tachyarrhythmias. Circulation 67:1347–55
  • Hynes J, Marroquin LD, Hynes J, et al. (2006). Investigation of drug-induced mitochondrial toxicity using fluorescence-based oxygen-sensitive probes. Toxicol Sci 92:186–200
  • Jocelyn PC. (1987). Spectrophotometric assay of thiols. Methods Enzymol 143:44–67
  • Latini R, Tognoni G, Kates RE. (1984). Clinical pharmacokinetics of amiodarone. Clin Pharmacokinet 9:136–56
  • Leeder RG, Rafeiro E, Brien JF, et al. (1996). Evaluation of reactive oxygen species involvement in amiodarone pulmonary toxicity in vivo and in vitro. J Biochem Toxicol 11:147–60
  • Lo LW, Koch CJ, Wilson DF. (1996). Calibration of oxygen-dependent quenching of the phosphorescence of Pd-meso-tetra (4-carboxyphenyl) porphine: a phosphor with general application for measuring oxygen concentration in biological systems. Anal Biochem 236:153–60
  • Lüllmann H, Lüllmann-Rauch R, Wassermann O. (1978). Lipidosis induced by amphiphilic cationic drugs. Biochem Pharmacol 27:1103–8
  • Martin WJ, Howard DM. (1985). Amiodarone-induced lung toxicity. In vitro evidence for the direct toxicity of the drug. Am J Pathol 120:344–50
  • Mulder JE, Brien JF, Racz WJ, et al. (2011). Mechanisms of amiodarone and desethylamiodarone cytotoxicity in non-transformed human peripheral lung epithelial cells. J Pharmacol Exp Ther 336:551–9
  • Nicolescu AC, Ji Y, Comeau JL, et al. (2008). Direct mitochondrial dysfunction precedes reactive oxygen species production in amiodarone-induced toxicity in human peripheral lung epithelial HPL1A cells. Toxicol Appl Pharmacol 227:370–9
  • Papiris SA, Triantafillidou C, Kolilekas L, et al. (2010). Amiodarone: review of pulmonary effects and toxicity. Drug Saf 33:539–58
  • Pollak PT. (1999). Clinical organ toxicity of antiarrhythmic compounds: ocular and pulmonary manifestations. Am J Cardiol 84:37R–45R
  • Range FT, Hilker E, Breithardt G, et al. (2013). Amiodarone-induced pulmonary toxicity—a fatal case report and literature review. Cardiovas Drugs Therapy 27:247–54
  • Reasor MJ, Kacew S. (1996). An evaluation of possible mechanisms underlying amiodarone-induced pulmonary toxicity. Proc Soc Exp Biol Med 212:297–304
  • Schwaiblmair M, Berghaus T, Haeckel T, et al. (2010). Amiodarone-induced pulmonary toxicity: an under-recognized and severe adverse effect? Clin Res Cardiol 99:693–700
  • Shaban S, Marzouqi F, Al Mansouri A, et al. (2010). Oxygen measurements via phosphorescence. Computer Meth Programs Biomed 100:265–8
  • Souid A-K, Fahey RC, Aktas MK, et al. (2001). Blood thiols following amifostine and mesna infusions, a Pediatric Oncology Group study. Drug Metabol Dispos 29:1–7
  • Souid A-K, Tack KA, Galvan KA, Penefsky HS. (2003). Immediate effects of anticancer drugs on mitochondrial oxygen consumption. Biochem Pharmacol 66:977–87
  • Wolkove N, Baltzan M. (2009). Amiodarone pulmonary toxicity. Can Respir J 16:43–8

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.