Hesperidin restores experimentally induced neurotoxicity in Wistar rats

References

• Afzal M, Khan R, Kazmi I, Anwar F. (2013). Hepatoprotective potential of new steroid against carbon tetrachloride-induced hepatic injury. Mol Cell Biochem 378:275–81
   PubMedGoogle Scholar
• Agrawal R, Mishra B, Tyagi E, et al. (2010). Effect of curcumin on brain insulin receptors and memory functions in STZ (ICV) induced dementia model of rat. Pharmacol Res 61:247–52
   PubMed Web of Science ®Google Scholar
• Albarracin SL, Stab B, Casas Z, et al. (2012). Effects of natural antioxidants in neurodegenerative disease. Nutr Neurosci 15:1–9
   PubMed Web of Science ®Google Scholar
• Almroth BC, Sturve J, Berglund A, Förlin L. (2005). Oxidative damage in eelpout (Zoarces viviparus), measured as protein carbonyls and TBARS, as biomarkers. Aquat Toxicol 73:171–80
   PubMed Web of Science ®Google Scholar
• Altas S, Kızıl G, Kızıl M, et al. (2011). Protective effect of Diyarbakır watermelon juice on carbon tetrachloride-induced toxicity in rats. Food Chem Toxicol 49:2433–8
   PubMed Web of Science ®Google Scholar
• Antoniades C, Carageorgiou H, Tsakiris S. (2002). Effects of (−)deprenyl (selegiline) on acetylcholinesterase and Na+K+-ATPase activities in adult rat whole brain. Pharmacol Res 46:165–9
   PubMedGoogle Scholar
• Biasibetti R, Tramontina AC, Costa AP, et al. (2013). Green tea (−) epigallocatechin-3-gallate reverses oxidative stress and reduces acetylcholinesterase activity in a streptozotocin-induced model of dementia. Behav Brain Res 236:186–93
   PubMed Web of Science ®Google Scholar
• Board PG, Menon D. (2013). Glutathione transferases, regulators of cellular metabolism and physiology. Biochim Biophys Acta 1830:3267–88
   PubMed Web of Science ®Google Scholar
• Boer LA, Panatto JP, Fagundes DA, et al. (2009). Inhibition of mitochondrial respiratory chain in the brain of rats after hepatic failure induced by carbon tetrachloride is reversed by antioxidants. Brain Res Bull 80:75–8
   PubMedGoogle Scholar
• Chaudhary S, Parvez S. (2012). An in vitro approach to assess the neurotoxicity of valproic acid-induced oxidative stress in cerebellum and cerebral cortex of young rats. Neuroscience 225:258–68
   PubMed Web of Science ®Google Scholar
• Chen YR, Chen CL, Zhang L, et al. (2005). Superoxide generation from mitochondrial NADH dehydrogenase induces self-inactivation with specific protein radical formation. J Biol Chem 280:37339–48
   PubMed Web of Science ®Google Scholar
• Dabas A, Nagpure NS, Kumar R, et al. (2012). Assessment of tissue-specific effect of cadmium on antioxidant defense system and lipid peroxidation in freshwater murrel, Channa punctatus. Fish Physiol Biochem 38:469–82
   PubMed Web of Science ®Google Scholar
• Dalle-Donne I, Giustarini D, Colombo R, et al. (2003). Protein carbonylation in human diseases. Trends Mol Med 9:169–76
   PubMed Web of Science ®Google Scholar
• Dickinson DA, Forman HJ. (2002). Cellular glutathione and thiols metabolism. Biochem Pharmacol 64:1019–26
   PubMed Web of Science ®Google Scholar
• El-Sayed el SM, Abo-Salem OM, Abd-Ellah MF, Abd-Alla GM. (2008). Hesperidin, an antioxidant flavonoid, prevents acrylonitrile-induced oxidative stress in rat brain. J Biochem Mol Toxicol 22:268–73
   PubMed Web of Science ®Google Scholar
• Freeman LR, Keller JN. (2012). Oxidative stress and cerebral endothelial cells: regulation of the blood-brain-barrier and antioxidant based interventions. Biochim Biophys Acta 1822:822–9
   PubMed Web of Science ®Google Scholar
• Gaur V, Aggarwal A, Kumar A. (2011). Possible nitric oxide mechanism in the protective effect of hesperidin against ischemic reperfusion cerebral injury in rats. Indian J Exp Biol 49:609–18
   PubMed Web of Science ®Google Scholar
• Ghareeb DA, Hafez HS, Hussien HM, Kabapy NF. (2011). Non-alcoholic fatty liver induces insulin resistance and metabolic disorders with development of brain damage and dysfunction. Metab Brain Dis 26:253–67
   PubMed Web of Science ®Google Scholar
• Govil N, Chaudhary S, Waseem M, Parvez S. (2012). Postnuclear supernatant: an in vitro model for assessing cadmium-induced neurotoxicity. Biol Trace Elem Res 146:402–9
   PubMed Web of Science ®Google Scholar
• Haque R, Bin-Hafeez B, Parvez S, et al. (2003). Aqueous extract of walnut (Juglans regia L.) protects mice against cyclophosphamide induced biochemical toxicity. Hum Exp Toxicol 22:473–80
   PubMed Web of Science ®Google Scholar
• Ibrahim SS. (2008). Protective effect of hesperidin, a citrus bioflavonoid, on diabetes-induced brain damage in rats. J Appl Sci Res 4:84–95
   Google Scholar
• Jain M, Parmar HS. (2011). Evaluation of antioxidative and anti-inflammatory potential of hesperidin and naringin on the rat air pouch model of inflammation. Inflamm Res 60:483–91
   PubMed Web of Science ®Google Scholar
• Jaitovich AA, Bertorello AM. (2006). Na+, K+-Atpase: an indispensable ion pumping-signaling mechanism across mammalian cell membranes. Semin Nephrol 26:386–92
   PubMed Web of Science ®Google Scholar
• Jayakumar T, Sakthivel M, Thomas PA, Geraldine P. (2008). Pleurotus ostreatus, an oyster mushroom, decreases the oxidative stress induced by carbon tetrachloride in rat kidneys, heart and brain. Chem Biol Interact 176:108–20
   PubMed Web of Science ®Google Scholar
• Kamaraj S, Ramakrishnan G, Anandakumar P, et al. (2009). Antioxidant and anticancer efficacy of hesperidin in benzo(a)pyrene induced lung carcinogenesis in mice. Invest New Drugs 27:214–22
   PubMed Web of Science ®Google Scholar
• Kovacic P, Somanathan R. (2012). Redox processes in neurodegenerative disease involving reactive oxygen species. Curr Neuropharmacol 10:289–302
   PubMed Web of Science ®Google Scholar
• Li ZH, Zlabek V, Grabic R, et al. (2010). Modulation of glutathione-related antioxidant defense system of fish chronically treated by the fungicide propiconazole. Comp Biochem Physiol 152:392–8
   Google Scholar
• Lingrel JB. (2010). The physiological significance of the cardiotonic steroid/ouabain-binding site of the Na+,K+-ATPase. Annu Rev Physiol 72:395–412
   PubMed Web of Science ®Google Scholar
• Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. (1951). Protein measurement with the Folin phenol reagent. J Biol Chem 193:265–75
   PubMed Web of Science ®Google Scholar
• Manna P, Bhattacharyya S, Das J, et al. (2011). Phytomedicinal role of pithecellobium dulce against CCl4-mediated hepatic oxidative impairments and necrotic cell death. Evid Based Complement Alternat Med 2011:832805
   PubMedGoogle Scholar
• Masella R, Di Benedetto R, Varì R, et al. (2005). Novel mechanisms of natural antioxidant compounds in biological systems: involvement of glutathione and glutathione-related enzymes. J Nutr Biochem 16:577–86
   PubMed Web of Science ®Google Scholar
• Meyer JH, Ginovart N, Boovariwala A, et al. (2006). Elevated monoamine oxidase a levels in the brain: an explanation for the monoamine imbalance of major depression. Arch Gen Psychiatry 63:1209–16
   PubMed Web of Science ®Google Scholar
• Nones J, Stipursky J, Costa SL, Gomes FC. (2010). Flavonoids and astrocytes crosstalking: implications for brain development and pathology. Neurochem Res 35:955–66
   PubMedGoogle Scholar
• Parent MB, Baxter MG. (2004). Septohippocampal acetylcholine: involved in but not necessary for learning and memory? Learn Mem 11:9–20
   PubMed Web of Science ®Google Scholar
• Pradeep K, Park SH, Ko KC. (2008). Hesperidin a flavanoglycone protects against γ-irradiation induced hepatocellular damage and oxidative stress in Sprague–Dawley rats. Eur J Pharmacol 587:273–80
   PubMed Web of Science ®Google Scholar
• Ryou SH, Kang MS, Kim KI, et al. (2012). Effects of green tea or Sasa quelpaertensis bamboo leaves on plasma and liver lipids, erythrocyte Na efflux, and platelet aggregation in ovariectomized rats. Nutr Res Pract 6:106–12
   PubMedGoogle Scholar
• Sahu BD, Kuncha M, Sindhura GJ, Sistla R. (2013). Hesperidin attenuates cisplatin-induced acute renal injury by decreasing oxidative stress, inflammation and DNA damage. Phytomedicine 20:453–60
   PubMed Web of Science ®Google Scholar
• Salem HRA, El-Raouf Mohamed AA, Saleh EM, Shalaby KAF. (2012). Influence of Hesperidin combined with Sinemet on genetical and biochemical abnormalities in rats suffering from Parkinson’s disease. Life Sci J 9:930–45
   Web of Science ®Google Scholar
• Samudram P, Vasuki R, Rajeshwari H, et al. (2009). Antioxidant and antihepatotoxic activities of ethanolic crude extract of Melia azedarach and Piper longum. J Med Plants Res 3:1078–83
   Google Scholar
• Saquib Q, Attia SM, Siddiqui MA, et al. (2012). Phorate-induced oxidative stress, DNA damage and transcriptional activation of p53 and caspase genes in male Wistar rats. Toxicol Appl Pharmacol 259:54–65
   PubMed Web of Science ®Google Scholar
• Secci D, Bolasco A, Chimenti P, Carradori S. (2011). The state of the art of pyrazole derivatives as monoamine oxidase inhibitors and antidepressant/anticonvulsant agents. Curr Med Chem 18:5114–44
   PubMed Web of Science ®Google Scholar
• Seminotti B, da Rosa MS, Fernandes CG, et al. (2012). Induction of oxidative stress in brain of glutaryl-CoA dehydrogenase deficient mice by acute lysine administration. Mol Genet Metab 106:31–8
   PubMedGoogle Scholar
• Soliman AM, Fahmy SR. (2011). Protective and curative effects of the 15 KD isolated protein from the Peganum harmala L. seeds against carbon tetrachloride induced oxidative stress in brain, tests and erythrocytes of rats. Eur Rev Med Pharmacol Sci 15:888–99
   PubMedGoogle Scholar
• Srivastava A, Shivanandappa T. (2010). Hepatoprotective effect of the root extract of Decalepis hamiltonii against carbon tetrachloride-induced oxidative stress in rats. Food Chem 118:411–17
   Web of Science ®Google Scholar
• Tabassum H, Parvez S, Rehman H, et al. (2007). Nephrotoxicity and its prevention by taurine in tamoxifen induced oxidative stress in mice. Hum Exp Toxicol 26:509–18
   PubMed Web of Science ®Google Scholar
• Tamilselvam K, Nataraj J, Janakiraman U, et al. (2013). Antioxidant and anti-inflammatory potential of hesperidin against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced experimental Parkinson's disease in mice. Int J Nutr Pharmacol Neurol Dis 3:294–302
   Google Scholar
• Tiwari V, Kuhad A, Bishnoi M, Chopra K. (2009). Chronic treatment with tocotrienol, an isoform of vitamin E, prevents intracerebroventricular streptozotocin-induced cognitive impairment and oxidative–nitrosative stress in rats. Pharmacol Biochem Behav 93:183–9
   PubMed Web of Science ®Google Scholar
• Tsai CF, Hsu YW, Ting HC, et al. (2013). The in vivo antioxidant and antifibrotic properties of green tea (Camellia sinensis, Theaceae). Food Chem 136:1337–44
   PubMed Web of Science ®Google Scholar
• Viswanatha GL, Shylaja H, Sandeep Rao KS, et al. (2012). Hesperidin ameliorates immobilization-stress-induced behavioral and biochemical alterations and mitochondrial dysfunction inmice bymodulating nitrergic pathway. ISRN Pharmacol 2012:479570
   PubMedGoogle Scholar