Protection of mice against lipopolysaccharide-induced endotoxic shock by pinocembrin is correlated with regulation of cytokine secretion

References

• Bartold, P. M., and Haynes, D. R. 1991. IL-6 production by human gingival fibroblasts. J. Periodontal. Res. 26:339–345
   PubMed Web of Science ®Google Scholar
• Benjamim, C. F., Hogaboam, C. M., and Kunkel, S. L. 2004. The chronic consequences of severe sepsis. J. Leukocyte Biol. 75:408–412
   PubMed Web of Science ®Google Scholar
• Beutler, B., Milsark, I. W., and Cerami, A. 1985. Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin. Science 229:869–871
   PubMed Web of Science ®Google Scholar
• Calderone, V., Chericoni, S., Martinelli, C., et al. 2004. Vasorelaxing effects of flavonoids: Investigation on possible involvement of potassium channels. Naunyn-Schmied. Arch. Pharmacol. 370:290–298
   PubMed Web of Science ®Google Scholar
• Chao, W. W., Kuo, Y. H., Hsieh, S. L., and Lin, B. F. 2011. Inhibitory effects of ethyl acetate extract of Andrographis paniculata on NF-κB trans-activation activity and LPS-induced acute inflammation in mice. Evid. Based Complement Alt. Med. doi:10.1093/ecam/nep120
   Google Scholar
• Choi, Y. H., and Park, H. Y. 2012. Anti-inflammatory effects of spermidine in lipopolysaccharide-stimulated BV2 microglial cells. J. Biomed. Sci. 19:31
   PubMedGoogle Scholar
• Cohen, J. 2002. The immunopathogenesis of sepsis. Nature 420:885–891
   PubMed Web of Science ®Google Scholar
• Dhingra, S., Sharma, A. K., Arora, R. C., et al. 2009. IL-10 attenuates TNFα-induced NF-κB pathway activation and cardiomyocyte apoptosis. Cardiovasc. Res. 82:59–66
   PubMed Web of Science ®Google Scholar
• Gao, M., Liu, R., Zhu, S. Y., and Du, G. H. 2008b. Acute neurovascular unit protective action of pinocembrin against permanent cerebral ischemia in rats. J. Asian Nat. Prod. Res. 10:551–558
   PubMed Web of Science ®Google Scholar
• Gao, M., Zhang, W. C., Liu, Q. S., et al. 2008a. Pinocembrin prevents glutamate-induced apoptosis in SH-SY5Y neuronal cells via decrease of bax/bcl-2 ratio. Eur. J. Pharmacol. 591:73–79
   PubMed Web of Science ®Google Scholar
• Guang, H. M., and Du, G. H. 2006. Protections of pinocembrin on brain mitochondria contribute to cognitive improvement in chronic cerebral hypo-perfused rats. Eur. J. Pharmacol. 542:77–83
   PubMed Web of Science ®Google Scholar
• Guha, M., and Mackman, N. 2001. LPS induction of gene expression in human monocytes. Cell Signal. 13:85–94
   PubMed Web of Science ®Google Scholar
• Guyon, A., Massa, F., Rovere, C., and Nahon, J. L. 2008. “How cytokines can influence the brain: A role for chemokines?” J. Neuroimmunol. 198:46–55
   PubMed Web of Science ®Google Scholar
• Hanasaki, Y., Ogawa, S., and Fukui, S. 1994. Correlation between active oxygen scavenging and anti-oxidative effects of flavonoids. Free Rad. Biol. Med. 16:845–850
   PubMed Web of Science ®Google Scholar
• Hotchkiss, R. S., and Karl, I. E. 2003. The pathophysiology and treatment of sepsis. New Engl. J. Med. 348:138–150
   PubMed Web of Science ®Google Scholar
• Huang, W. Z., Zhang, C. F., Zhang, M., and Wang, Z. T. 2007. A new biphenyl-propanoid from Alpinia katsumadai. J. Chin. Chem. Soc. 54:1553–1556
   Google Scholar
• Kalantar-Zadeh, K., Ikizler, T. A., Block, G., et al. 2003. Malnutrition-inflammation complex syndrome in dialysis patients: causes and consequences. Am. J. Kidney Dis. 42:864–881
   PubMed Web of Science ®Google Scholar
• Kielian, T., Bearden, E. D., Baldwin, A. C., and Esen, N. 2004. IL-1 and TNFα play a pivotal role in the host immune response in a mouse model of Staphylococcus aureus-induced experimental brain abscess. J. Neuropathol. Exp. Neurol. 63:381–396
   PubMed Web of Science ®Google Scholar
• Kim, S. J., Jeong, H. J., Moon, P. D., et al. 2005. Anti-inflammatory activity of gumigangh-waltang through the inhibition of NF-κB activation in peritoneal macrophages. Biol. Pharm. Bull. 28:233–237
   PubMed Web of Science ®Google Scholar
• Lantz, R. C., Chen, G. J., Solyom, A. M., et al. 2005. The effect of turmeric extracts on inflammatory mediator production. Phytomedicine 12:445–452
   PubMed Web of Science ®Google Scholar
• Liu, R., Wu, C. X., Zhou, D., et al. 2012. Pinocembrin protects against β-amyloid-induced toxicity in neurons through inhibiting receptors for advanced glycation end products (RAGE)-independent signaling pathways and regulating mitochondrion-mediated apoptosis. BMC Med. 10:105
   PubMed Web of Science ®Google Scholar
• Middleton, E. J., Kandaswami, C., and Theoharides, T. C. 2000. The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease, and cancer. Pharmacol. Rev. 52:673–751
   PubMed Web of Science ®Google Scholar
• Morrissey, P. J., and Charrier, K. 1994. Treatment of mice with IL-1 before infection increases resistance to a lethal challenge with Salmonella typhimurium. The effect correlates with the resistance allele at the Ity locus. J. Immunol. 153:212–219
   PubMedGoogle Scholar
• Namas, R., Ghuma, A., Hermus, L., et al. 2009. The acute inflammatory response in trauma/hemorrhage and traumatic brain injury: Current state and emerging prospects. Libyan J. Med. 4:97–103
   PubMed Web of Science ®Google Scholar
• Parrillo, J. E. 1993. Pathogenetic mechanisms of septic shock. New Engl. J. Med. 328:1471–1477
   PubMed Web of Science ®Google Scholar
• Soromou, L. W., Chu, X., Jiang, L., et al. 2012. In vitro and in vivo protection provided by pinocembrin against lipopolysaccharide-induced inflammatory responses. Int. Immunopharmacol. 14:66–74
   PubMed Web of Science ®Google Scholar
• Touil, Y. S., Fellous, A., Scherman, D., and Chabot, G. G. 2009. Flavonoid-induced morphological modifications of endothelial cells through microtubule stabilization. Nutr. Cancer 61:310–321
   PubMed Web of Science ®Google Scholar
• Tracey, K. J., Fong, Y., Hesse, D. G., et al. 1987. Anti-cachectin/-TNF monoclonal antibodies prevent septic shock during lethal bacteremia. Nature 330:662–664
   PubMed Web of Science ®Google Scholar
• Van, M. E., Sawamura, Y., Diserens, A. C., et al. 1990. Human glioblastoma cells release IL-6 in vivo and in vitro. Cancer Res. 50:6683–6688
   PubMedGoogle Scholar
• Wang, Q., Zhang, Y., Hall, J. P., et al. 2007. A rat pharmacokinetic and pharmacodynamic model for assessment of lipopolysaccharide-induced TNFα production. J. Pharmacol. Toxicol. Meth. 56:67–71
   PubMedGoogle Scholar
• Wu, M., and Gu, Z. 2009. Screening of bioactive compounds from Moutan Cortex and their anti-inflammatory activities in rat synoviocytes. Evidence-Based Complement Alt. Med. 6:57–63
   PubMedGoogle Scholar
• Zemse, S. M., Chiao, C. W., Hilgers Rob, H. P., and Webb, R. C. 2010. IL-10 inhibits the in vivo and in vitro adverse effects of TNFα on the endothelium of murine aorta. Am. J. Physiol. Heart Circ. Physiol. 299:1160–1167
   Google Scholar