797
Views
20
CrossRef citations to date
0
Altmetric
Research Article

Effect of recombinant human IFNγ in the treatment of chronic pulmonary complications due to sulfur mustard intoxication

, , , , , , & show all
Pages 72-77 | Received 22 Mar 2013, Accepted 16 Apr 2013, Published online: 14 Jun 2013

References

  • Akerboom, T. P., and Sies, H. 1981. Assay of glutathione, glutathione disulfide, and glutathione mixed disulfides in biological samples. Meth. Enzymol. 77:373–382
  • Anonymous. 1986. Reports of specialists appointed by the Secretary General to investigate allegations by the Islamic Republic of Iran concerning the use of chemical weapons. USA: New York Security Council of United Nations document, pp. 16433
  • Calvet, J. H., Planus, E., Rouet, P., et al. 1999. Matrix metalloproteinase gelatinases in sulfur mustard-induced acute airway injury in guinea pigs. Am. J. Physiol. 276:L754–762
  • Chakrabarti, S., and Patel, K. D. 2005. Matrix metalloproteinase-2 (MMP-2) and MMP-9 in pulmonary pathology. Exp. Lung Res. 31:599–621
  • Chance, B., and Maehly, A. C. 1995. Assay of catalase and peroxidase. In: Methods in Enzymology (Colowick, S. P., and Kaplan, N. D.). New York: Academic Press, pp. 764–791
  • Cheresh, P., Kim, S. J., Tulasiram, S., and Kamp, D. W. 2013. Oxidative stress and pulmonary fibrosis. Biochim. Biophys. Acta. 1832:1028--1040
  • Corbel, M., Belleguic, C., Boichot, E., and Lagente, V. 2002. Involvement of gelatinases (MMP-2 and MMP-9) in development of airway inflammation and pulmonary fibrosis. Cell Biol. Toxicol. 18:51–61
  • de Vries, J. E. 1995. Immunosuppressive and anti-inflammatory properties of IL-10. Ann. Med. 27:537–541
  • Du Bois, R. M. 1999. IFNγ-1b for treatment of idiopathic pulmonary fibrosis. New Engl. J. Med. 341:1302–1324
  • Emad, A., and Emad, Y. 2007. CD4/CD8 ratio and cytokine levels of the BAL fluid in patients with bronchiectasis caused by sulfur mustard gas inhalation. J. Inflamm. (Lond.) 4:2
  • Emad, A., and Rezaian, G. R. 1997. The diversity of the effects of sulfur mustard gas inhalation on respiratory system 10 years after a single, heavy exposure: Analysis of 197 cases. Chest 112:734–738
  • Geirsson, A., Singh, M., Ali, R., et al. 2012. Modulation of TGFβ signaling and extracellular matrix production in myxomatous mitral valves by angiotensin II receptor blockers. Circulation 126:S189–S197
  • Ghabili, K., Agutter, P. S., Ghanei, M., et al. 2011. Sulfur mustard toxicity: History, chemistry, pharmacokinetics, and pharmacodynamics. Crit. Rev. Toxicol. 41:384–403
  • Ghanei, M., Panahi, Y., Mojtahedzadeh, M., et al. 2006. Effect of IFNγ on lung function of mustard gas exposed patients, after 15 years. Pulm. Pharmacol. Ther. 19:148–153
  • Grande, J. P., Melder, D. C., and Zinsmeister, A. R. 1997. Modulation of collagen gene expression by cytokines: Stimulatory effect of TGFβ1, with divergent effects of EGF and TNFα on collagen Type I and collagen Type IV. J. Lab. Clin. Med. 130:476–486
  • Gruner, S., Liebenthal, C., Heusser, C., et al. 1991. The influence of IFNγ and IL-4 on IgE production in B-lymphocytes of patients with atopic dermatitis. Possible criterion for selection of patients for interferon therapy. Acta Derm. Venereol. 71:484–487
  • Gurujeyalakshmi, G., and Giri, S. N. 1995. Molecular mechanisms of anti-fibrotic effect of IFNγ in bleomycin-mouse model of lung fibrosis: Down-regulation of TGFβ and procollagen I and III gene expression. Exp. Lung Res. 21:791–808
  • Han, S., Espinoza, L. A., Liao, H., et al. 2004. Protection by anti-oxidants against toxicity and apoptosis induced by the sulphur mustard analog 2-chloro-ethylethyl sulphide (CEES) in Jurkat T-cells and normal human lymphocytes. Br. J. Pharmacol. 141:795–802
  • Hengge, U. R., Ruzicka, T., Schwartz, R. A., and Cork, M. J. 2006. Adverse effects of topical glucocorticosteroids. J. Am. Acad. Dermatol. 54:1–15
  • Husain, K., Dube, S. N., Sugendran, K., et al. 1996. Effect of topically-applied sulphur mustard on anti-oxidant enzymes in blood cells and body tissues of rats. J. Appl. Toxicol. 16:245–248
  • Jafari, M. 2007. Dose- and time-dependent effects of sulfur mustard on anti-oxidant system in liver and brain of rat. Toxicology 231:30–39
  • Jones, P. W., Harding, G., Berry, P., et al. 2009. Development and first validation of the COPD Assessment Test. Eur. Respir. J. 34:648–654
  • Keane, M. P. 2008. Role of chemokines and cytokines in lung fibrosis. Eur. Respir. Rev. 17:151–156
  • Khateri, S., Ghanei, M., Keshavarz, S., et al. 2003. Incidence of lung, eye, and skin lesions as late complications in 34,000 Iranians with wartime exposure to mustard agent. J. Occup. Environ. Med. 45:1136–1143
  • Korkmaz, A., Oter, S., Sadir, S., et al. 2005. Peroxynitrite may be involved in bladder damage caused by cyclophosphamide in rats. J. Urol. 173:1793–1796
  • Lagente, V., Manoury, B., Nénan, S., et al. 2005. Role of matrix metalloproteinases in the development of airway inflammation and remodeling. Braz. J. Med. Biol. Res. 38:1521–1530
  • Li, X. M., and Zhai, L. D. 2008. Influence of IFNγ in combination with methylprednisolone on proliferation of human embryonic lung fibroblast. J. Clin. Rehab. Tissue Eng. Res. 12:2829–2833
  • Losa Garcia, J. E., Rodriguez, F. M., Martin de Cabo, M. R., et al. 1999. Evaluation of inflammatory cytokine secretion by human alveolar macrophages. Med. Inflamm. 8:43–51
  • Louis, S. M., Johnstone, D., Russell, N. J., et al. 1989. Antibodies to calcitonin-gene related peptide reduce inflammation induced by topical mustard oil but not that due to carrageenan in the rat. Neurosci. Lett. 102:257–260
  • Malaviya, R., Sunil, V. R., Cervelli, J., et al. 2010. Inflammatory effects of inhaled sulfur mustard in rat lung. Toxicol. Appl. Pharmacol. 248:89–99
  • Meguro, M., Barley, E. A., Spencer, S., and Jones, P. W. 2007. Development and validation of an improved, COPD-Specific Version of the St. George Respiratory Questionnaire. Chest 132:456–463
  • Naghii, M. R. 2002. Sulfur mustard intoxication, oxidative stress, and anti-oxidants. Mil. Med. 167:573–575
  • Panahi, Y., Davoudi, S. M., Sadr, S. B., et al. 2008. Impact of pruritus on quality of life in sulfur mustard-exposed Iranian veterans. Int. J. Dermatol. 47:557–561
  • Panahi, Y., Davoudi, S. M., Sahebkar, A., et al. 2012a. Efficacy of aloe vera/olive oil cream vs. betamethasone cream for chronic skin lesions following sulfur mustard exposure: A randomized double-blind clinical trial. Cutan. Ocul. Toxicol. 31:95–103
  • Panahi, Y., Sahebkar, A., Amiri, M., et al. 2012b. Improvement of sulphur mustard-induced chronic pruritus, quality of life and anti-oxidant status by curcumin: Results of a randomised, double-blind, placebo-controlled trial. Br. J. Nutr. 108:1272–1279
  • Panahi, Y., Sahebkar, A., Davoudi, S. M., et al. 2012c. Efficacy and safety of immunotherapy with interferon-γ in the management of chronic sulfur mustard-induced cutaneous complications: Comparison with topical betamethasone 1%. ScientificWorldJournal 2012;285274
  • Panahi, Y., Sahebkar, A., Parvin, S., and Saadat, A. 2012d. A randomized controlled trial on the anti-inflammatory effects of curcumin in patients with chronic sulphur mustard-induced cutaneous complications. Ann. Clin. Biochem. 49:580–588
  • Panahi, Y., Sarayani, A., Beiraghdar, F., et al. 2012e. Management of sulfur mustard-induced chronic pruritus: A review of clinical trials. Cutan. Ocul. Toxicol. 31:220–225
  • Pohanka, M., and Stetina, R. 2009. Shift of oxidants and anti-oxidants levels in rats as a reaction to exposure to sulfur mustard. J. Appl. Toxicol. 29:643–647
  • Pourfarzam, S., Ghazanfari, T., Yaraee, R., et al. 2009. Serum levels of IL-8 and IL-6 in the long-term pulmonary complications induced by sulfur mustard: Sardasht-Iran Cohort Study. Int. Immunopharmacol. 9:1482–1488
  • Prior, C., and Haslam, P. L. 1992. In vivo levels and in vitro production of IFNγ in fibrosing interstitial lung diseases. Clin. Exp. Immunol. 88:28–287
  • Raghu, G., Masta, S., Meyers, D., and Narayanan, A. S. 1989. Collagen synthesis by normal and fibrotic human lung fibroblasts and the effect of TGFβ. Am. Rev. Respir. Dis. 140:95–100
  • Rahman, I. 2005. The role of oxidative stress in the pathogenesis of COPD: Implications for therapy. Treat. Respir. Med. 4:175–200
  • Sahebkar, A. 2012. Baicalin as a potentially promising drug for the management of sulfur mustard induced cutaneous complications: A review of molecular mechanisms. Cutan. Ocul. Toxicol. 31:226–234
  • Sato, A., Tsuji, K., Yamamura, M., et al. 1998. Increased Type 2 cytokine expression by both CD4+ CD45RO+ T-cells and CD8+ CD45RO+ T-cells in blood circulation is associated with high serum IgE but not with atopic dermatitis. J. Invest. Dermatol. 111:1079–1084
  • Thannickal, V. J., Lee, D. Y., White, E. S., et al. 2003. Myofibroblast differentiation by TGFβ1 is dependent on cell adhesion and integrin signaling via focal adhesion kinase. J. Biol. Chem. 278:12384–12389
  • Thomas, S. R., and Stocker, R. 1999. Anti-oxidant activities and redox regulation of IFNγ-induced tryptophan metabolism in human monocytes and macrophages. Adv. Exp. Med. Biol. 467:541–552
  • Tomasek, J. J., Gabbiani, G., Hinz, B., et al. 2002. Myofibroblasts and mechano-regulation of connective tissue remodelling. Nat. Rev. Mol. Cell. Biol. 3:349–363
  • Tzouvelekis, A., Bouros, E., and Bouros, D. 2010. The immunology of pulmonary fibrosis: The role of TH1/TH2/TH17/Treg cells. Pneumon 23:13–20
  • Uchiyama, M., and Mihara, M. 1978. Determination of malondialdehyde precursor in tissue by thiobarbituric acid test. Anal. Biochem. 34:271–278
  • Wen, F. Q., Liu, X., Kobayashi, T., et al. 2004. IFNγ inhibits TGFβ production in human airway epithelial cells by targeting Smads. Am. J. Respir. Cell Mol. Biol. 30:816–822
  • Yaraee, R., Ghazanfari, T., Faghihzadeh, S., et al. 2009. Alterations in the serum levels of soluble L, P, and E-selectin 20 years after sulfur mustard exposure: Sardasht-Iran Cohort Study. Int. Immunopharmacol. 9:1477–1481
  • Ziesche, R., and Block, L. H. 2000. Mechanisms of anti-fibrotic action of IFNγ-1b in pulmonary fibrosis. Wien Klin. Wochenschr. 112:785–790

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.