1,605
Views
25
CrossRef citations to date
0
Altmetric
Research Article

In vitro study of AFB1 and AFM1 effects on human lymphoblastoid Jurkat T-cell model

, , , , &
Pages 353-358 | Received 18 Jun 2013, Accepted 20 Sep 2013, Published online: 22 Oct 2013

References

  • Asim, M., Sarma, M. P., Thayumanavan, L., and Kar, P. 2011. Role of aflatoxin B1 as a risk for primary liver cancer in north Indian population. Clin. Biochem. 44:1235–1240
  • Bianco, G., Fontanella, B., Severino, L., et al. 2012a. Nivalenol and deoxynivalenol affect rat intestinal epithelial cells: A concentration-related study. PLOS One 7 e52051:1–14
  • Bianco, G., Russo, R., Marzocco, S., et al. 2012b. Modulation of macrophage activity by aflatoxins B1 and B2 and their metabolites aflatoxins M1 and M2. Toxicon 59:644–650
  • Bodine, A. B., Fischer, S. F., and Gangiee, S. 1984. Effects of aflatoxin B1 and major metabolites on PHA-stimulated lymphoblastogenesis of bovine lymphocytes. J. Dairy Sci. 67:110–114
  • Bondy, G. S., and Pestka, J. J. 2000. Immunomodulation by fungal toxins. J. Toxicol. Environ. Health 3:109–143
  • Braca, A., Dal Piaz, F., Marzocco, S., et al. 2011. Triterpene derivatives as inhibitors of protein involved in the inflammatory process: molecules interfering with phospholipase A2, cycloxygenase, and lipoxygenase. Curr Drug Targets 12:302--321
  • Bruchim, Y., Segev, G., Sela, U., et al. 2012. Accidental fatal aflatoxicosis due to contaminated commercial diet in 50 dogs. Res. Vet. Sci. 93:279–287
  • Caruso, M., Mariotti, A., Zizzadoro, C., et al. 2009. A clonal cell line (BME-UV1) as a possible model to study bovine mammary epithelial metabolism: Metabolism and cytotoxicity of aflatoxin B1. Toxicon 53:400–408
  • Colombo, M., Hamelin, C., Kouassi, E., et al. 2004. Differential effects of mercury, lead, and cadmium on IL-2 production by Jurkat T-cells. Clin. Immunol. 111:311–322
  • Cusumano, V., Costa, G. B., Trifiletti, R., et al. 1995. Functional impairment of rat Kupffer cells induced by aflatoxin B1 and its metabolites. FEMS Immunol. Med. Microbiol. 10:151–155
  • Dimitri, R. A., and Gabal, M. A. 1996. Immunosuppressant activity of aflatoxin ingestion in rabbits measured by response to Mycobacterium bovis antigen I. Cell-mediated immune response measured by skin test reaction. Vet. Hum. Toxicol. 38:333–336
  • Egal, S., Hounsa, A., Gong, Y. Y., et al. 2005. Dietary exposure to aflatoxin from maize and groundnut in young children from Benin and Togo, West Africa. Int. J. Food Microbiol. 104:215–224
  • Gallagher, E. P., Wienkers, L. C., Kunze, K. L., et al. 1994. Role of CYP1A2 and 3A4 in the bioactivation of aflatoxin B1 in human liver microsomes. Cancer Res. 54:101–108
  • Hamid, A. S., Tesfamariam, I. G., Zhang, Y., and Zhang, Z. G. 2013. Aflatoxin B1-induced hepatocellular carcinoma in developing countries: Geographical distribution, mechanism of action and prevention. Oncol. Lett. 5:1087–1092
  • Han, S. H., Jeon, Y. J., Yea, S. S., and Yang, K. H. 2001. Suppression of IL-2 gene expression by aflatoxin B1 is mediated through down-regulation of the NF-AT and AP-1 transcription factors. Toxicol. Lett. 108:1–10
  • Harvey, R. B., Edrington, T. S., Kubena, L. F., et al. 1995. Influence of aflatoxin and fumonisin B1-containing culture material on growing barrows. Am. J. Vet. Res. 56:1668–1672
  • IARC Working Group on the Evaluation of Carcinogenic Risks to Humans International Agency for Research on Cancer. 1993. Some naturally occurring substances: food items and constituents, heterocyclic aromatic amines and mycotoxins. IARC monographs on the evaluation of carcinogenic risks to humans: v. 56. Geneva: World Health Organization, International Agency for Research on Cancer
  • Kumar, V., and Sharma, A. 2010. Neutrophils: Cinderella of innate immune system. Int. Immunopharmacol. 10:1325–1334
  • Linevsky, J. K., Pothoulakis, C., Keates, S., et al. 1997. IL-8 release and neutrophil activation by Clostridium difficile toxin-exposed human monocytes. Am. J. Physiol. 273:G1333–G1340
  • Liu, B. H., Yu, F. Y., Chan, M. H., and Yang, Y. L. 2002. The effects of mycotoxins, fumonisin B1, and aflatoxin B1 on primary swine alveolar macrophages. Toxicol. Appl. Pharmacol. 180:197–204
  • Livak, K. J., and Schmittgen, T. D. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2−ΔΔCt method. Methods 25:402–408
  • Luongo, D., Severino, L., Bergamo, P., et al. 2006. Interactive effects of fumonisin B1 and α-zearalenol on proliferation and cytokine expression in Jurkat T-cells. Toxicol. In Vitro 20:1403–1410
  • Lye, M. S., Ghazali, A. A., Mohan, J., et al. 1995. An outbreak of acute hepatic encephalopathy due to severe aflatoxicosis in Malaysia. Am. J. Trop. Med. Hyg. 53:68–72
  • Marin, M. L., Murtha, J., Dong, W., and Pestka, J. J. 1996. Effects of mycotoxins on cytokine production and proliferation in EL-4 thymoma cells. J. Toxicol. Environ. Health 48:379–396
  • Marzocco, S., Russo, R., Bianco, G., et al. 2009. Pro-apoptotic effects of nivalenol and deoxynivalenol trichothecenes in J774A.1 murine macrophages. Toxicol. Lett. 89:21–26
  • Meissonier, M., Pinton, P., Laffitte, J., et al. 2008. Immunotoxicity of aflatoxin B1: Impairment of the cell-mediated response to vaccine antigen and modulation of cytokine expression. Toxicol. Appl. Pharmacol. 231:142–149
  • Meky, F. A., Hardie, L. J., Evans, S. W., and Wild, C. P. 2001. Deoxynivalenol-induced immunomodulation of human lymphocyte proliferation and cytokine production. Food Chem. Toxicol. 39:827–836
  • Methenitou, G., Maravelias, C., Athanaselis, S., et al. 2001. Immuno-modulative effects of aflatoxins and selenium on human natural killer cells. Vet. Hum. Toxicol. 43:232–234
  • Moon, E. Y., Rhee, D. K., and Pyo, S. 1999. In vitro suppressive effect of aflatoxin B1 on murine peritoneal macrophage functions. Toxicology 133:171–179
  • Muller, I., Munder, M., Kropf, P., and Hansch, G.M. 2009. Polymorphonuclear neutrophils and T lymphocytes: Strange bedfellows or brothers in arms? Trends Immunol. 30:522–530
  • Ndebele, K., Tchounwou, P. B., and McMurray, R. W. 2004. Coumestrol, bisphenol-A, DDT, and TCDD modulation of IL-2 expression in activated CD4+ Jurkat T-cells. Int. J. Environ. Res. Public. Health. 1:3–11
  • Oostingh, G. J., Wichmann, G., Schmittner, M., et al. 2009. The cytotoxic effects of the chlorpyrifos and diazinon differ from their immunomodulating effects. J. Immunotoxicol. 6:136–145
  • Pestka, J. J., Uzarski, R. L., and Islam, Z. 2005. Induction of apoptosis and cytokine production in Jurkat human T-cells by deoxynivalenol: Role of mitogen-activated protein kinases and comparison to other ketotrichothecenes. Toxicology 206:207–219
  • Prandini, A., Tansini, G., Sigolo, S., et al. 2009. On the occurrence of aflatoxin M1 in milk and dairy products. Food Chem. Toxicol. 47:984–991
  • Probst, C., Njapau, H., and Cotty, P. J. 2007. Outbreak of an acute aflatoxicosis in Kenya in 2004: Identification of the causal agent. Appl. Environ. Microbiol. 73:2762–2764
  • Quian, G., Tang, L., Guo, X., et al. 2013. Aflatoxin B1 modulates expression of phenotypic markers and cytokines by splenic lymphocytes of male F344 rats. J. Appl. Toxicol. DOI 10.1002/jat.2866
  • Rocha, O., Ansari, K., and Doohan. F. M. 2005. Effects of trichothecene mycotoxins on eukaryotic cells: A review. Food Addit. Contam. 22:369–378
  • Roda, E., Coccini, T., Acerbi, D., et al. 2010. Comparative in vitro and in vivo myelotoxicity of aflatoxins B1 and M1 on hemopoietic progenitors (BFU-E, CFU-E and CFU-GM): Species-related susceptibility. Toxicol. In Vitro 24:217–223
  • Severino, L., Luongo, D., Bergamo, P., et al. 2006. Mycotoxins nivalenol and deoxynivalenol differently modulate cytokine mRNA expression in Jurkat T-cells. Cytokine 36:75–82
  • Silvotti, L., Patterino, C., Bonomi, A., and Cabassi, E. 1997. Immunotoxicological effects on piglets of feeding sows diets containing aflatoxins. Vet. Res. 141:469–472
  • Tipton, D. A., Lyle, B., Babich, H., and Dabbous, M. K. 2003. In vitro cytotoxic and anti-inflammatory effects of myrrh oil on human gingival fibroblasts and epithelial cells. Toxicol. In Vitro 17:301–310
  • Ul-Hassan, Z., Khan, M. Z., Khan, A., and Javed, I. 2012. Immunological status of the progeny of breeder hens kept on ochratoxin A (OTA)- and aflatoxin B1 (AFB1)-contaminated feeds. J. Immunotoxicol. 9:381–391
  • Viegas, S., Veiga, L., Malta-Vacas, J., et al. 2012. Occupational exposure to aflatoxin (AFB) in poultry production. J. Toxicol. Environ. Health 75:1330–1340
  • Wang, J., and Liu, X. M. 2007. Contamination of aflatoxins in different kinds of foods in China. Biomed. Environ. Sci. 20:483–487
  • Zhao, M. F., Qu, X. J., Qu, J. L., et al. 2013. The role of e3 ubiquitin ligase cbl proteins in IL-2-induced Jurkat T-cell activation. BioMed Res. Int. 2013:430861

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.