1,720
Views
29
CrossRef citations to date
0
Altmetric
Review Article

The link between MHC class I abnormalities of tumors, oncogenes, tumor suppressor genes, and transcription factors

Pages 308-310 | Received 02 Oct 2013, Accepted 10 Dec 2013, Published online: 30 Jan 2014

References

  • Atkins, D., Ferrone, S., Schmahl, G. E., et al. 2004. Down-regulation of HLA class I antigen processing molecules: An immune escape mechanism of renal cell carcinoma? J. Urol. 171:885–889
  • Bukur, J., Herrmann, F., Handke, D., et al. 2010. Identification of E2F1 as an important transcription factor for the regulation of tapasin expression. J. Biol. Chem. 285:30419–30426
  • Ferris, R. L., Whiteside, T. L., and Ferrone, S. 2006. Immune escape associated with functional defects in antigen-processing machinery in head and neck cancer. Clin. Cancer Res. 12:3890–3895
  • Jensen, P. E. 2007. Recent advances in antigen processing and presentation. Nat. Immunol. 8:1041–1048
  • Kageshita, T., Hirai, S., Ono, T., et al. 1999. Down-regulation of HLA class I antigen-processing molecules in malignant melanoma: Association with disease progression. Am. J. Pathol. 154:745–754
  • Khan, A. N., Gregorie, C. J., and Tomasi, T. B. 2008. Histone deacetylase inhibitors induce TAP, LMP, Tapasin genes, and MHC class I antigen presentation by melanoma cells. Cancer Immunol. Immunother. 57:647–654
  • Mehta, A. M., Jordanova, E. S., Kenter, G. G., et al. 2008. Association of antigen processing machinery and HLA class I defects with clinico-pathological outcome in cervical carcinoma. Cancer Immunol. Immunother. 57:197–206
  • Meissner, M., Reichert, T. E., Kunkel, M., et al. 2005. Defects in the human leukocyte antigen class I antigen processing machinery in head and neck squamous cell carcinoma: Association with clinical outcome. Clin. Cancer Res. 11:2552–2560
  • Nie, Y., Yang, G., Song, Y., et al. 2001. DNA hypermethylation is a mechanism for loss of expression of the HLA class I genes in human esophageal squamous cell carcinomas. Carcinogenesis 22:1615–1623
  • Norell, H., Carlsten, M., Ohlum, T., et al. 2006. Frequent loss of HLA-A2 expression in metastasizing ovarian carcinomas associated with genomic haplotype loss and HLA-A2-restricted HER-2/neu-specific immunity. Cancer Res. 66:6387–6394
  • Respa, A., Bukur, J., Ferrone, S., et al. 2011. Association of IFNγ signal transduction defects with impaired HLA class I antigen processing in melanoma cell lines. Clin. Cancer Res. 17:2668–2678
  • Rock, K. L., York, I. A., and Goldberg, A. L. 2004. Post-proteasomal antigen processing for major histocompatibility complex class I presentation. Nat. Immunol. 5:670–677
  • Romero, J. M., Jiménez, P., Cabrera, T., et al. 2005. Coordinated down-regulation of the antigen presentation machinery and HLA class I/β2-microglobulin complex is responsible for HLA-ABC loss in bladder cancer. Int. J. Cancer 113:605–610
  • Saveanu, L., Carroll, O., Lindo, V., et al. 2005. Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum. Nat. Immunol. 6:689–697
  • Seliger, B. 2008. Different regulation of MHC class I antigen processing components in human tumors. J. Immunotoxicol. 5:361–367
  • Seliger, B., Maeurer, M. J., and Ferrone, S. 2000. Antigen-processing machinery breakdown and tumor growth. Immunol. Today 21:455–464
  • Seliger, B., Ritz, U., and Ferrone, S. 2006. Molecular mechanisms of HLA class I antigen abnormalities following viral infection and transformation. Int. J. Cancer 118:129–138
  • Seliger, B., Stoehr, R., Handke, D., et al. 2010. Association of HLA class I antigen abnormalities with disease progression and early recurrence in prostate cancer. Cancer Immunol. Immunother. 59:529–540
  • Sigalotti, L., Fratta, E., Coral, S., et al. 2004. Intra-tumor heterogeneity of cancer/testis antigens expression in human cutaneous melanoma is methylation-regulated and functionally reverted by 5-aza-2′-deoxycytidine. Cancer Res. 64:9167–9171
  • Tanaka, K., Tsuchikawa, T., Miyamoto, M., et al. 2012. Down-regulation of Human Leukocyte Antigen class I heavy chain in tumors is associated with a poor prognosis in advanced esophageal cancer patients. Int. J. Oncol. 40:965–974
  • Vitale, M., Rezzani, R., Rodella, L., et al. 1998. HLA class I antigen and transporter associated with antigen processing (TAP1 and TAP2) down-regulation in high-grade primary breast carcinoma lesions. Cancer Res. 58:737–742
  • York, I. A., Goldberg, A. L., Mo, X. Y., and Rock, K. L. 1999. Proteolysis and class I major histocompatibility complex antigen presentation. Immunol. Rev. 172:49–66

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.