References
- Abrams, S. I. 2010. A multi-functional role of interferon regulatory factor-8 in solid tumor and myeloid cell biology. Immunol Res. 46:59–71
- Aliberti, J., Schulz, O., Pennington, D. J., et al. 2003. Essential role for ICSBP in the in vivo development of murine CD8alpha+ dendritic cells. Blood 101:305–310
- Businaro, L., De Ninno, A., Schiavoni, G., et al. 2013. Cross-talk between cancer and immune cells: Exploring complex dynamics in a microfluidic environment. Lab. Chip 13:229–239
- Danilin, S., Merkel, A. R., Johnson, J. R., et al. 2012. Myeloid-derived suppressor cells expand during breast cancer progression and promote tumor-induced bone destruction. Oncoimmunology 1:1484–1494
- Dvorak, H. F., Weaver, V. M., Tlsty, T. D., and Bergers, G. 2011. Tumor microenvironment and progression. J. Surg. Oncol. 103:468–474
- Fridman, W. H., Pages, F., Sautes-Fridman, C., and Galon, J. 2012. The immune contexture in human tumors: Impact on clinical outcome. Nat. Rev. Cancer 12:298–306
- Gabriele, L., and Ozato, K. 2007. The role of the interferon regulatory factor (IRF) family in dendritic cell development and function. Cytokine Growth Factor Rev. 18:503–510
- Gabriele, L., Phung, J., Fukumoto, J., et al. 1999. Regulation of apoptosis in myeloid cells by interferon consensus sequence-binding protein. J. Exp. Med. 190:411–421
- Gabrilovich, D. I., Ostrand-Rosenberg, S., and Bronte, V. 2012. Coordinated regulation of myeloid cells by tumors. Nat. Rev. Immunol. 12:253–268
- Galon, J., Fridman, W. H., and Pages, F. 2007. The adaptive immunologic microenvironment in colorectal cancer: A novel perspective. Cancer Res. 67:1883–1886
- Hanahan, D., and Weinberg, R. A. 2011. Hallmarks of cancer: The next generation. Cell 144:646–674
- Holtschke, T., Lohler, J., Kanno, Y., et al. 1996. Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene. Cell 87:307–317
- Ma, H., Xu, H., and Qin, J. 2013. Biomimetic tumor microenvironment on a microfluidic platform. Biomicrofluidics 7:11501–11514
- Mattei, F., Schiavoni, G., Borghi, P., et al. 2006. ICSBP/IRF-8 differentially regulates antigen uptake during dendritic-cell development and affects antigen presentation to CD4+ T-cells. Blood 108:609–617
- Mattei, F., Schiavoni, G., Sestili, P., et al. 2012. IRF-8 controls melanoma progression by regulating the cross-talk between cancer and immune cells within the tumor microenvironment. Neoplasia 14:1223–1235
- Pages, F., Galon, J., Dieu-Nosjean, M. C., et al. 2010. Immune infiltration in human tumors: A prognostic factor that should not be ignored. Oncogene 29:1093–1102
- Rocca, S., Schiavoni, G., Sali, M., et al. 2013. Interferon regulatory factor 8-deficiency determines massive neutrophil recruitment but T-cell defect in fast-growing granulomas during tuberculosis. PLoS One 8:e62751
- Schiavoni, G., Gabriele, L., and Mattei, F. 2013. The tumor microenvironment: A pitch for multiple players. Front. Oncol. 3:90–105
- Schiavoni, G., Mattei, F., Borghi, P., et al. 2004. ICSBP is critically involved in normal development and trafficking of Langerhans cells and dermal dendritic cells. Blood 103:2221–2228
- Schiavoni, G., Mattei, F., Sestili, P., et al. 2002. ICSBP is essential for development of mouse Type I IFN-producing cells and for generation and activation of CD8alpha+ dendritic cells. J. Exp. Med. 196:1415–1425
- Shimizu, M., Shimamura, M., Owaki, T., et al. 2006. Anti-angiogenic and anti-tumor activities of IL-27. J. Immunol. 176:7317–7324
- Shurin, M. R., Shurin, G. V., Lokshin, A., et al. 2006. Intra-tumoral cytokines/chemokines/growth factors and tumor infiltrating dendritic cells: Friends or enemies? Cancer Metast. Rev. 25:333–356
- Tamura, T., and Ozato, K. 2002. ICSBP/IRF-8: Its regulatory roles in the development of myeloid cells. J. Interferon Cytokine Res. 22:145–152
- Tsujimura, H., Tamura, T., Gongora, C., et al. 2003. ICSBP/IRF-8 retrovirus transduction rescues dendritic cell development in vitro. Blood 101:961–969
- Waight, J. D., Netherby, C., Hensen, M. L., et al. 2013. Myeloid-derived suppressor cell development is regulated by a STAT/IRF-8 axis. J. Clin. Invest. 123:4464–4478