Role of Chinese herbal medicinal ingredients in secretion of cytokines by PCV2-induced endothelial cells

References

• Chae, C. 2005. A review of porcine circovirus 2-associated syndromes and diseases. Vet. J. 169:326–336
   PubMed Web of Science ®Google Scholar
• Chen, H., Yin, J., Deng, Y., et al. 2012. Protective effects of ginsenoside Rg1 against hypertension target-organ damage in spontaneously hypertensive rats. BMC Comp. Alt. Med. 12:53
   PubMed Web of Science ®Google Scholar
• Czuprynski, C. J. 2009. Host response to bovine respiratory pathogens. Animal Health Res. Rev. 10:141–143
   PubMedGoogle Scholar
• Darwich, L., Balasch, M., Plana-Duran, J., et al. 2003. Cytokine profiles of peripheral blood mononuclear cells from pigs with postweaning multi-systemic wasting syndrome in response to mitogen, superantigen, or recall viral antigens. J. Gen. Virol. 84:3453–3457
   PubMed Web of Science ®Google Scholar
• Darwich, L., Segales, J., Resendes, A., et al. 2008. Transient correlation between viremia levels and IL-10 expression in pigs subclinically infected with porcine circovirus Type 2 (PCV2). Res. Vet. Sci. 84:194–198
   PubMed Web of Science ®Google Scholar
• Fort, M., Fernandes, L. T., Nofrarias, M., et al. 2009. Development of cell-mediated immunity to porcine circovirus Type 2 (PCV2) in caesarean-derived, colostrum-deprived piglets. Vet. Immunol. Immunopharmacol. 129:101–107
   PubMed Web of Science ®Google Scholar
• Hocke, A. C., Ermert, M., Althoff, A., et al. 2006. Regulation of IL-4, IL-13, IL-10, and their downstream components in LPS-exposed rat lungs. Comparison of constitutive expression between rats and humans. Cytokine 33:199–211
   PubMed Web of Science ®Google Scholar
• Hu, G., Xue, J., Duan, H., et al. 2010. IFNγ induces IFNα and IFNIβ expression in cultured rat intestinal mucosa microvascular endothelial cells. Immunopharmacol. Immunotoxicol. 32:656–662
   PubMed Web of Science ®Google Scholar
• Hu, G., Xue, J. Z., Liu, J., et al. 2012. Baicalin Induces IFNα/β and IFNγ expression in cultured mouse pulmonary microvascular endothelial cells. J. Integrative Agric. 11:646–654
   Web of Science ®Google Scholar
• Hu, Y., Chen, X., Duan, H., et al. 2009. Pulsatilla decoction and its active ingredients inhibit secretion of NO, ET-1, TNFα, and IL-1α in LPS-induced rat intestinal microvascular endothelial cells. Cell. Biochem. Funct. 27:284–288
   PubMed Web of Science ®Google Scholar
• Karupiah, G. 1998. Type 1 and Type 2 cytokines in anti-viral defense. Vet. Immunol. Immunopathol. 63:105–109
   PubMed Web of Science ®Google Scholar
• Kato, M., Pu, M. Y., Isobe, K., et al. 1994. Characterization of the immunoregulatory action of Saikosaponin-D (SSD). Cell. Immunol. 159:15–25
   PubMed Web of Science ®Google Scholar
• Kato, M., Pu, M. Y., Isobe, K., et al. 1995. Cell type-oriented differential modulatory actions of saikosaponin-d on growth responses and DNA fragmentation of lymphocytes triggered by receptor-mediated and receptor-bypassed pathways. Immunopharmacol. Immunotoxicol. 29:207–213
   Web of Science ®Google Scholar
• Kienzle, N., Buttigieg, K., Groves, P., et al. 2002. A clonal culture system demonstrates that IL-4 induces a sub-population of non-cytolytic T-cells with low CD8, perforin, and granzyme expression. J. Immunol. 168:1672–1681
   PubMed Web of Science ®Google Scholar
• Lehle, K., Straub, R. H., Morawietz, H., and Kunz-Schughart, L. A. 2010. Relevance of disease- and organ-specific endothelial cells for in vitro research. Cell Biol. Intl. 34:1231–1238
   PubMed Web of Science ®Google Scholar
• Levy, Y., and Brouet, J. C. 1994. IL-10 prevents spontaneous death of germinal center B-cells by induction of the bcl-2 protein. J. Clin. Invest. 93:424–428
   PubMed Web of Science ®Google Scholar
• Li, B., Ma, J., Liu. Y., et al. 2012. Complete genome sequence of a highly prevalent porcine circovirus 2 isolated from piglet stool samples in China. J. Virol. 86:4716–4723
   PubMed Web of Science ®Google Scholar
• Lin, X. L., Lin, B. Q., Pan, S. L., et al. 2013. Effect of TCM on growth and immune - response to hog cholera vaccine of weaned piglets carrying naturally acquired porcine circovirus Type 2. Fujian J. Agric. Sci. 28:957–961
   Google Scholar
• Liu, M., Zhao, X., Xiao, L., et al. 2014. Cytotoxicity of the compounds isolated from Pulsatilla chinensis saponins and apoptosis induced by 23-hydroxybetulinic acid. Pharm. Biol. 15:1–9
   Web of Science ®Google Scholar
• Liu, S. J., Ju, W. Z., Liu, Z. X., et al. 2009. Pharmacokinetic study of saikosaponin-A in rat plasma by LC ESI-MS. CPB 25:1380–1383
   Google Scholar
• Mankertz, A., Domingo, M., Folch, J. M., et al. 2000. Characterisation of PCV-2 isolates from Spain, Germany, and France. Virus Res. 66:65–77
   PubMed Web of Science ®Google Scholar
• Moore, K. W., de Waal Malefyt, R., Coffman, R. L., and O'Garra, A. 2001. IL-10 and the IL-10 receptor. Annu. Rev. Immunol. 19:683–765
   PubMed Web of Science ®Google Scholar
• Muraille, E., and Leo, O. 1998. Revisiting the TH1/TH2 paradigm. Scand. J. Immunol. 47:1–9
   PubMed Web of Science ®Google Scholar
• Muruve, D. A. 2004. The innate immune response to adenovirus vectors. Human Gene Ther. 15:1157–1166
   PubMed Web of Science ®Google Scholar
• Na-Bangchang, K., and Karbwang, J. 2014. Traditional herbal medicine for control of tropical diseases. Trop. Med. Health 42:3–13
   PubMedGoogle Scholar
• Nelms, K., Keegan, A. D., Zamorano, J., et al. 1999. The IL-4 receptor: Signaling mechanisms and biologic functions. Annu. Rev. Immunol. 17:701–738
   PubMed Web of Science ®Google Scholar
• Ning, N., Dang, X., Bai, C., et al. 2012. Panax notoginsenoside produces neuroprotective effects in rat model of acute spinal cord ischemia-reperfusion injury. J. Ethnopharmacol. 139:504–512
   PubMed Web of Science ®Google Scholar
• Niu, Q. X., Zheng, J., Chen, Z. Y., and Lin, J. L. 2011. Influence of trypsin on IL-10, IL-12, and IFNγ release from endothelial cells. Hainan Med. J. 22:1–3
   Google Scholar
• Opriessnig, T., Meng, X., and Halbur, P. G. 2007. Porcine circovirus Type 2-associated disease: Update on current terminology, clinical manifestations, pathogenesis, diagnosis, and intervention strategies. J. Vet. Diag. Invest. 19:591–615
   PubMed Web of Science ®Google Scholar
• Ouyang, W., Ranganath, S. H., Weindel, K., et al. 1998. Inhibition of TH1 development mediated by GATA-3 through an IL-4-independent mechanism. Immunity 9:745–755
   PubMed Web of Science ®Google Scholar
• Pate, M., Damarla, V., Chi, D. S., et al. 2010. Endothelial cell biology: Role in inflammatory response. Adv. Clin. Chem. 52:109–130
   PubMed Web of Science ®Google Scholar
• Peng, X. D., Dai, L. L., Huang, C. Q., et al. 2009. Relationship between anti-fibrotic effect of Panax notoginseng saponins and serum cytokines in rat hepatic fibrosis. Biochem. Biophys. Res. Commun. 388:31–34
   PubMed Web of Science ®Google Scholar
• Sahni, S. K. 2007. Endothelial cell infection and hemostasis. Thrombosis Res. 119:531–549
   PubMed Web of Science ®Google Scholar
• Salazar-Onfray, F., Charo, J., Petersson, M., et al. 1997. Down-regulation of expression and function of transporter associated with antigen processing in murine tumor cell lines expressing IL-10. J. Immunol. 159:3195–3202
   PubMed Web of Science ®Google Scholar
• Segales, J., Domingo, M., Chianini, F., et al. 2004. Immunosuppression in post-weaning multi-systemic wasting syndrome-affected pigs. Vet. Microbiol. 98:151–158
   PubMed Web of Science ®Google Scholar
• Sengupta, S., Toh, S. A., Sellers, L. A., et al. 2004. Modulating angiogenesis: The yin and the yang in ginseng. Circulation 110:1219–1225
   PubMed Web of Science ®Google Scholar
• Shimoda, K., van Deursen, J., Sangster, M. Y., et al. 1996. Lack of IL-4-induced TH2 response and IgE class switching in mice with disrupted STAT6 gene. Nature 380:630–633
   PubMed Web of Science ®Google Scholar
• Sprague, A. H., and Khalil, R. A. 2009. Inflammatory cytokines in vascular dysfunction and vascular disease. Biochem. Pharmacol. 78:539–552
   PubMed Web of Science ®Google Scholar
• Steiner, E., Balmelli, C., Gerber, H., et al. 2009. Cellular adaptive immune response against porcine circovirus Type 2 in subclinically infected pigs. BMC Vet. Res. 5:45
   PubMed Web of Science ®Google Scholar
• Stevenson, L. S., McCullough, K., Vincent, I., et al. 2006. Cytokine and C-reactive protein profiles induced by porcine circovirus Type 2 experimental infection in 3-wk-old piglets. Viral Immunol. 19:189–195
   PubMed Web of Science ®Google Scholar
• Sun, B., Xiao, J., Sun, X. B., and Wu, Y. 2013. Notoginsenoside R1 attenuates cardiac dysfunction in endotoxemic mice: An insight into estrogen receptor activation and PI3K/Akt signaling. Br. J. Pharmacol. 168:1758–1770
   PubMed Web of Science ®Google Scholar
• Sun, Y., Cai, T. T., Zhou, X. B., and Xu, Q. 2009. Saikosaponin-A inhibits proliferation and activation of T-cells through cell cycle arrest and induction of apoptosis. Intl. Immunopharmacol. 9:978–983
   PubMed Web of Science ®Google Scholar
• Takeda, K., Tanaka, T., Shi, W., et al. 1996. Essential role of STAT6 in IL-4 signaling. Nature 380:627–630
   PubMed Web of Science ®Google Scholar
• Tundis, R., Bonesi, M., Deguin, B., et al. 2009. Cytotoxic activity and inhibitory effect on nitric oxide production of triterpene saponins from the roots of Physospermum verticillatum (Waldst & Kit) (Apiaceae). Bioorgan. Med. Chem. 17:4542–4547
   PubMed Web of Science ®Google Scholar
• Verma, S., Nakaoke, R., Dohgu, S., and Banks, W. A. 2006. Release of cytokines by brain endothelial cells: A polarized response to LPS. Brain. Behav. Immun. 20:449–455
   PubMed Web of Science ®Google Scholar
• Wang, S. C., Zhao, H. P., and Huang, M. J. 2005. Pharmacokinetic of saikosaponin D in Wuling capsules in mouse. Chinese Trad. Patent Med. 27:809–811
   Google Scholar
• Wang, X., and Liu, Z. 2014. Prevention and treatment of viral respiratory infections by traditional Chinese herbs. Chinese Med. J. Peking 127:1344–1350
   PubMed Web of Science ®Google Scholar
• Wei, Y. Y., Hu, T. J., Su, Z. J., et al. 2012. Immunomodulatory and anti-oxidant effects of carboxymethylpachymaran on the mice infected with PCV2. Int. J. Biol. Macromol. 50:713–719
   PubMed Web of Science ®Google Scholar
• Wong, V. K., Hu, T. J., Zhou, H., et al. 2009. Mechanistic study of Saikosaponin-D (SSD) on suppression of murine T-lymphocyte activation. J. Cell. Biochem. 107:303–315
   PubMed Web of Science ®Google Scholar
• Yi, D. M., Zhang, M. L., Yu, P. S., et al. 2009. Curative effects of the Chinese herbal compound on the mixture infection of PCV-2 and bacteria. Prog. Vet. Med. 30:122–124
   Google Scholar
• Yin, L., Hu, G., Suo, Z. W., et al. 2007. ConA induces intestinal mucous microvascular endothelial cells to secrete IFNγ. Acta Anat. Sinica 38:486–488
   Google Scholar