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Original Article

Case 4 Renal Toxicity Induced by Valproic Acid (Depakene)

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Pages 863-868 | Published online: 09 Jul 2009

References

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  • Lenoir G R, Perignon J-L, Gubler M-C, Broyer M. Valproic acid: A possible cause of proximal tubular renal syndrome. J Pediatr 1981; 98: 503–4
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  • Coude F X, Grimber G, Pelet A, Benoit Y. Action of the antiepileptic drug, valproic acid, on fatty acid oxidation in isolated rat hepatocytes. Biochem Biophys Res Commun 1983; 115: 730–6
  • Kendler B S. Carnitine: An overview of its role in preventive medicine. Prev Med 1986; 15: 373–90
  • Ohtani Y, Endo F, Matsuda J. Carnitine deficiency and hyperammonemia associated with valproic acid therapy. J Pediatr 1982; 101: 782–5

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