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Original Article

Case 5 Tuberous Sclerosis Variant with Production of Rosenthal Fibers (AlphaB-Crystallin)

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Pages 869-873 | Published online: 09 Jul 2009

References

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  • Iwaki T, Wisniewski T, Iwaki A, et al. Accumulations of alpha B-crystallin in central nervous system glia and neurons in pathologic conditions. Am J Pathol 1992; 140: 345–56
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  • Kandt R S, Pericak-Vance M A, Hung W Y, et al. Linkage studies in tuberous sclerosis. Chromosome 9? 11?, or maybe 14. Ann NY Acad Sci 1991; 615: 284–97
  • Herndon R M, Rubinstein L J, Freeman J M. Light and electron microscopic observations on Rosenthal fibers in Alexander's disease and multiple sclerosis. J Neuropathol Exp Neurol 1970; 29: 524–51
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  • Iwaki T, Kume-Iwaki A, Liem R KH, Goldman J E. Alpha-B-crystallin is expressed in non-lenticular tissues and accumulates in Alexander's disease brain. Cell 1989; 57: 71–8
  • Tomokane N, Iwaki T, Tateishi J, Iwaki A, Goldman J E. Rosenthal fibers share epitopes with alphaB-crystallin, glial fibrillary acidic protein, and ubiquitin, but not with vimentin. Am J Pathol 1991; 138: 875–85
  • Ngo J T, Klisak I, Dubin R A, et al. Assignment of the alphaB-crystallin gene to human chromosome 11. Genomics 1989; 5: 665–9

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