Immunohistologic Quantification of Pseudomonas Aeruginosa in the Tracheobronchial Tree from Patients with Cystic Fibrosis

References

• Wood R E, Boat T F, Doershuk C F. Cystic fibrosis. Am Rev Respir Dis 1976; 113: 833–78
   PubMed Web of Science ®Google Scholar
• Kulczycki L L, Murphy T M, Bellanti J A. Pseudomonas colonization in cystic fibrosis: A study of 160 patients. JAMA 1978; 240: 30–4
   PubMed Web of Science ®Google Scholar
• Reynolds H Y, Levine A S, Wood R E, Zierdt C H, Dale D C, Pennington J E. Pseudomonas aeruginosa infections: Persisting problems and current research to find new therapies. Ann Intern Med 1975; 82: 819–31
   PubMed Web of Science ®Google Scholar
• Bauernfeind A, Bertele R M, Harms K, et al. Qualitative and quantitative microbiological analysis of sputa of 102 patients with cystic fibrosis. Infection 1987; 15: 270–7
   PubMed Web of Science ®Google Scholar
• Doggett R G, Harrison G M. Pseudomonas aeruginosa: Immune status in patients with cystic fibrosis. Infect Immun 1972; 6: 628–635
   Google Scholar
• Lam J, Chan R, Lam K, Costerton J W. Production of mucoid microcolonies by Pseudomonas aeruginosa within infected lungs in cystic fibrosis. Infect Immun 1980; 28: 546–56
   PubMed Web of Science ®Google Scholar
• Baltimore R S, Mitchell M. Immunologic investigations of mucoid strains of Pseudomonas aeruginosa: Comparison of susceptibility to opsonic antibody in mucoid and non-mucoid strains. J Infect Dis 1980; 141: 238–47
   PubMedGoogle Scholar
• Pier G B. Pulmonary disease associated with Pseudomonas aeruginosa in cystic fibrosis: Current status of the host bacterium interaction. J Infect Dis 1985; 151: 575–80
   PubMed Web of Science ®Google Scholar
• Rosenfeld M, Ramsey B. Evolution of airway microbiology in the infant with cystic fibrosis: Role of nonpseudomonal and pseudomonal pathogens. Semin Respir Infect 1992; 7: 158–67
   Google Scholar
• Fick R B. Pathogenesis of the Pseudomonas lung lesion in cystic fibrosis. Chest 1989; 96: 158–64
   PubMed Web of Science ®Google Scholar
• Buret A, Cripps A W. The immunoevasive activities of Pseudomonas aeruginosa: Relevance for cystic fibrosis. Am Rev Respir Dis 1983; 148: 793–805
   Google Scholar
• Knoke J D, Stern R C, Doershuk C F, Boat T F, Matthews L W. Cystic fibrosis: The prognosis for five-year survival. Pediati Res 1978; 12: 676–9
   Google Scholar
• Smith A L, Redding G, Doershuk C, et al. Sputum changes associated with therapy for endobronchial exacerbation in cystic fibrosis. J Pediatr 1988; 112: 547–54
   PubMed Web of Science ®Google Scholar
• Hyatt A C, Chipps B E, Kumor K M, Mellits E D, Lietman P S, Rosenstein B J. A double-blind controlled trial of anti-Pseudomonas chemotherapy of acute respiratory exacerbations in patients with cystic fibrosis. J Pediatr 1981; 99: 307–11
   PubMed Web of Science ®Google Scholar
• Szaff M, Hoiby N, Flensborg E W. Frequent antibiotic therapy improves survival of cystic fibrosis patients with chronic Pseudomonas aeruginosa infection. Acta Paediatr Scand 1983; 72: 651–7
   PubMed Web of Science ®Google Scholar
• Konstan M W, Vargo K M, Davis P B. Ibuprofen attenuates the inflammatory response to Pseudomonas aeruginosa in a rat model of chronic pulmonary infection: Implications for antiinflammatory therapy in cystic fibrosis. Am Rev Respir Dis 1990; 141: 186–92
   PubMed Web of Science ®Google Scholar
• Auerbach H S, Williams M, Kirkpatrick J A, Colten H R. Alternate-day prednisone reduces morbidity and improves pulmonary function in cystic fibrosis. Lancet 1985; 2: 686–8
   PubMed Web of Science ®Google Scholar
• Pantin C F, Stead R J, Hodson M E, Batten J C. Prednisolone in the treatment of airflow obstruction in adults with cystic fibrosis. Thorax 1986; 41: 34–8
   Google Scholar
• Woods D E, Cryz S J, Friedman R L, Iglewski B H. Contribution of toxin A and elastase to virulence of Pseudomonas aeruginosa in chronic lung infection of rats. Infect Immun 1982; 36: 1223–8
   PubMed Web of Science ®Google Scholar
• Lapa eSilva J R, Guerreiro D, Noble B, Poulter L W, Cole P J. Immunotherapy of experimental bronchiectasis. Am J Respir Cell Mol Biol 1989; 1: 297–304
   Google Scholar
• Dovey M, Wisseman C L, Roggli V L, Roomans G M, Shelburne J D, Spock A. Ultrastructural morphology of the lung in cystic fibrosis. J Submicrosc Cytol Pathol 1989; 21: 521–34
   PubMedGoogle Scholar
• Baltimore R S, Dobek A S, Stark F R, Artenstein M S. Clinical and epidemiological correlates of Pseudomonas typing. J Infect Dis 1974; 130s: 53–9
   Google Scholar
• Fisher M W, Devlin H B, Gnabasik F J. Immunotype schema for Pseudomonas aeruginosa based on protective antigens. J Bacteriol 1969; 98: 835–6
   PubMedGoogle Scholar
• Baltimore R S. Prospects for a mucoid exopolysaccharide vaccine for the prevention of infection due to mucoid strains of Pseudomonas aeruginosa. Antibiot Chemother 1985; 36: 147–56
   Google Scholar
• Baltimore R S, Fick R B, Fino L. Antibody to multiple mucoid strains of Pseudomonas aeruginosa in patients with cystic fibrosis, measured by an enzyme-linked immunosorbent assay. Pediatr Res 1986; 20: 1085–90
   PubMedGoogle Scholar
• Baltimore R S, Christie CD C, Smith GJ W. Immunohistopathologic localization of Pseudomonas aeruginosa in lungs from patients with cystic fibrosis: Implications for the pathogenesis of progressive lung deterioration. Am Rev Respir Dis 1989; 140: 1650–61
   PubMed Web of Science ®Google Scholar
• Ostle B, Malone L C. Statistics in research. 4th ed. Iowa State University Press, Ames, IA 1988; 348–9
   Google Scholar
• Simel D L, Ingram P, Mastin J P, et al. Scanning electron microscopic study of the airways in normal children and in patients with cystic fibrosis and other lung diseases. Pediatr Pathol 1984; 2: 47–64
   Google Scholar
• Dupont M-J, Lapointe J-R. Quantitative effect of roxithromycin and rifampicin on mucoid cultures from directly plated sputum of cystic fibrosis patients chronically colonized with Pseudomonas aeruginosa. Drugs Exp Clin Res 1990; 16: 597–605
   Google Scholar
• Weibel E R. Morphometry of the human lung. Academic Press, New York 1963; 139
   Google Scholar