282
Views
29
CrossRef citations to date
0
Altmetric
ArticlesCriticle care

Utility of serum lactate to predict drug-overdose fatality

, , , &
Pages 730-736 | Received 07 May 2010, Accepted 22 Jun 2010, Published online: 12 Aug 2010

References

  • Substance Abuse and Mental Health Services Administration. Drug Abuse Warning Network, May 2005. http://druginfo.samhsa.gov/. Accessed on 2 June 2008.
  • Bronstein AC, Spyker DA, Cantilena LR, Green J, Rumack BH, Heard SE. 2007 Annual Report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 25th Annual Report. Clin Toxicol (Phila) 2008; 46:927–1057.
  • Paulozzi L, Crosby A, Ryan G. Increases in age-group-specific injury mortality – United States, 1999–2004. MMWR 2007; 56:1281–1284.
  • McCaig LF, Burt CW. Poisoning-related visits to emergency departments in the United States, 1993–1996. J Toxicol Clin Toxicol 1999; 37:817–826.
  • Schuster HP, Kapp S, Prellwitz W, Schuster CJ, Weilemann LS. Significance of hyperlactatemia in acute hypnotic drug poisoning. J Mol Med 1981; 59:599–605.
  • Fall PJ, Szerlip HM. Lactic acidosis: from sour milk to septic shock. J Intensive Care Med 2005; 20:255–271.
  • Shapiro NI, Howell MD, Talmor D, Nathanson LA, Lisbon A, Wolfe RE, Weiss JW. Serum lactate as a predictor of mortality in emergency department patients with infection. Ann Emerg Med 2005; 45:524–528.
  • Mikkelsen ME, Miltiades AN, Gaieski DF, Goyal M, Fuchs BD, Shah CV, Bellamy SL, Christie JD. Serum lactate is associated with mortality in severe sepsis independent of organ failure or shock. Crit Care Med 2009; 37:1670–1677.
  • Jones AE, Puskarich MA. Is lactate the “Holy Grail” of biomarkers for sepsis prognosis? Crit Care Med 2009; 37:1812–1813.
  • Mankis P, Jankowski S, Zhang H, Kahn RJ, Vincent JL. Correlation of serial blood lactate levels to organ failure and mortality after trauma. Am J Emerg Med 1995; 13:619–622.
  • Callaway DW, Shapiro NI, Donnino MW, Baker C, Rosen CL. Serum lactate and base deficit as predictors of mortality in normotensive elderly blunt trauma patients. J Trauma 2009; 66:1040–1044.
  • Valente S, Lazzeri C, Vecchio S, Giglioli C, Margheri M, Bernardo P, Comeglio M, Chiocchini S, Gensini GF. Predictors of in-hospital mortality after percutaneous coronary intervention for cardiogenic shock. Int J Cardiol 2007; 114:176–182.
  • Khosravani H, Shahpori R, Stelfox HT, Kirkpatrick AW, Laupland KB. Occurrence and adverse effect on outcome of hyperlactatemia in the critically ill. Crit Care 2009; 13:R90. Epub 2009 June 12.
  • Erickson TB, Thompson TM, Lu JJ. The approach to the patient with an unknown overdose. Emerg Med Clin North Am 2007; 25:249–281; abstract vii.
  • Burns MJ, Schwartzstein RM. General approach to drug poisoning in adults. In: Basow DS, ed. UpToDate, Waltham, MA; 2010.
  • Wolf SJ, Heard K, Sloan EP, Jagoda AS; American College of Emergency Physicians. Clinical policy: critical issues in the management of patients presenting to the emergency department with acetaminophen overdose. Ann Emerg Med 2007; 50:292–313.
  • Manini AF, Hoffman RS, McMartin KE, Nelson LS. Relationship between serum glycolate and falsely elevated lactate in severe ethylene glycol poisoning. J Anal Toxicol 2009; 33:174–176.
  • Dell’aglio DM, Perino LJ, Kazzi Z, Abramson J, Schwartz MD, Morgan BW. Acute metformin overdose: examining serum pH, lactate level, and metformin concentrations in survivors versus nonsurvivors: a systematic review of the literature. Ann Emerg Med 2009; 54:818–823.
  • Bernal W, Donaldson N, Wyncoll D, Wendon J. Blood lactate as an early predictor of outcome in paracetamol-induced acute liver failure: a cohort study. Lancet 2002; 359:558–563.
  • Miller KD, Cameron M, Wood LV, Dalakas MC, Ko-vacs LA. Lactic acidosis and hepatic steatosis associated with use of stavudine: report of four cases. Ann Int Med 2000; 133:192–195.
  • Baud FJ, Borron SW, Mégarbane B, Trout H, Lapostolle F, Vicaut E, Debray M, Bismuth C. Value of lactic acidosis in the assessment of the severity of acute cyanide poisoning. Crit Care Med 2002; 30:2044–2050.
  • Curb JD, McTiernan A, Heckbert SR, Kooperberg C, Stanford J, Nevitt M, Johnson KC, Proulx-Burns L, Pastore L, Criqui M, Daugherty S; WHI Morbidity and Mortality Committee. Outcomes ascertainment and adjudication in the Women’s Health Initiative. Ann Epidemiol 2003; 13:S122–S128.
  • Kuhn FE, Johnson MN, Gillis RA, Visner MS, Schaer GL. Effect of cocaine on the coronary circulation and systemic hemodynamics in dogs. J Am Coll Cardiol 1990; 16:1481–1491.
  • Love JN, Howell JM, Litovitz TL, Klein-Schwartz W. Acute beta blocker overdose: factors associated with the development of cardiovascular morbidity. J Toxicol Clin Toxicol 2000; 38:275–281.
  • Hulme J, Sherwood N. Severe lactic acidosis following alcohol related generalized seizures. Anaesthesia 2004; 59:1228–1230.
  • Boyer EW, Shannon M. The serotonin syndrome. N Engl J Med 2005; 352:1112–1120.
  • Jorens PG, Demey HE, Schepens PJ, Coucke V, Verpooten GA, Couttenye MM, Van Hoof V. Unusual D-lactic acid acidosis from propylene glycol metabolism in overdose. J Toxicol Clin Toxicol 2004; 42:163–169.
  • Stumvoll M, Nurjhan N, Perriello G, Dailey G, Gerich JE. Metabolic effects of metformin in non-insulin-dependent diabetes mellitus. N Engl J Med 1995; 333:550–554.
  • Cote HCF, Brumme ZL, Kevin JP, Craib J, Alexander CS, Wynhoven B, Ting L, Wong H, Harris M, Harrigan PR, O’Shaughnessy MV, Montaner JSG. Changes in mitochondrial DNA as a matter of nucleoside toxicity in HIV-infected patients. N Engl J Med 2002; 346:811–820.
  • Pal S, Chatterjee AK. Protective effect of methionine supplementation on arsenic-induced alteration of glucose homeostasis. Food Chem Toxicol 2004; 42:737–742.
  • Chi CH, Chen KW, Chan SH, Wu MH, Huang JJ. Clinical presentation and prognostic factors in sodium monofluoroacetate intoxication. J Toxicol Clin Toxicol 1996; 34:707–712.
  • Benaissa ML, Mégarbane B, Borron SW, Baud FJ. Is elevated plasma lactate a useful marker in the evaluation of pure carbon monoxide poisoning? Intensive Care Med 2003; 29:1372–1375.
  • Stolbach AI, Hoffman RS, Nelson LS. Mechanical ventilation was associated with acidemia in a case series of salicylate-poisoned patients. Acad Emerg Med 2008; 15:866–869.
  • Smith I, Kumar P, Molloy S, Rhodes A, Newman PJ, Grounds RM, Bennett ED. Base excess and lactate as prognostic indicators for patients admitted to intensive care. Intensive Care Med 2001; 27:74–83.
  • Rivers EP, Coba V, Visbal A, Whitmill M, Amponsah D. Management of sepsis with early resuscitation. Clin Chest Med 2008; 29:689–704.
  • Baud FJ, Borron SW, Megarbane B, Trout H, Lapostolle F, Vicaut E, Debray M, Bismuth C. Value of lactic acidosis in the assessment of the severity of acute cyanide poisoning. Crit Care Med 2002; 30:2044–2050.
  • Schmidt LE, Larsen FS. Prognostic implications of hyperlactemia, multiple organ failure and systemic inflammatory response syndrome in patients with acetaminophen-induced acute liver disease. Crit Care Med 2006; 34:337–343.
  • Jansen TC, van Bommel J, Mulder PG. The prognostic value of blood lactate levels relative to that of vital signs in the pre-hospital setting: a pilot study. Crit Care 2008; 12:R160.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.