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Letters to the Editor

Pediatric hepatotoxicity associated with Polygermander (Teucrium polium)

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Page 153 | Received 20 Oct 2011, Accepted 21 Nov 2011, Published online: 01 Feb 2012

References

  • Araz N, Bulbul S. Use of complementary and alternative medicine in a pediatric population in southern Turkey. Clin Invest Med 2011;34: 21–29.
  • Shahraki MR, Arab MR, Mirimokaddam E, Palan MJ. The effect of Teucrium polium (Calpoureh) on liver function, serum lipids and glucose in diabetic male rats. Iran Biomed J 2007;11:65–68.
  • Mattéi A, Rucay P, Samuel D, Feray C, Reynes M, Bismuth H. Liver transplantation for severe acute liver failure after herbal medicine (Teucrium polium) administration. J Hepatol 1995;22:597.
  • Polymeros D, Kamberoglou D, Tzias V. Acute cholestatic hepatitis caused by Teucrium polium (golden germander) with transient appearance of antimitochondrial antibody. J Clin Gastroenterol 2002;34:100–101.
  • Lekehal M, Pessayre D, Lereau JM, Moulis C, Fouraste I, Fau D. Hepatotoxicity of the herbal medicine germander: metabolic activation of its furano diterpenoids by cytochrome P450 3A Depletes cytoskeleton-associated protein thiols and forms plasma membrane blebs in rat hepatocytes. Hepatology 1996;24:212–218.

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