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Letter to the Editor

Limitations of AST/ALT ratio in paracetamol poisoning

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Page 580 | Received 17 Feb 2015, Accepted 05 Mar 2015, Published online: 26 Mar 2015

References

  • McGovern AJ, Vitkovitsky IV, Jones DL, Mullins ME. Can AST/ALT ratio indicate recovery after acute paracetamol poisoning? Clin Toxicol 2015; 53:164–167.
  • Ferner RE, Dear JW, Bateman DN. Management of paracetamol poisoning. BMJ 2011; 342:d2218.
  • Pakravan N, Simpson KJ, Waring WS, Bates CM, Bateman DN. Renal injury at first presentation as a predictor for poor outcome in severe paracetamol poisoning referred to a liver transplant unit. EurJ Clin Pharmacol 2009; 65:163–168.
  • Antoine DJ, Dear JW, Lewis PS, Platt V, Coyle J, Masson M, et al. Mechanistic biomarkers provide early and sensitive detection of acetaminophen-induced acute liver injury at first presentation to hospital. Hepatology 2013; 58:777–787.
  • Whyte IM, Buckley NA, Reith DM, Goodhew I, Seldon M, Dawson AH. Acetaminophen causes an increased international normalized ratio by reducing functional factor VII. Ther Drug Monit 2000; 22:742–748.

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