Fomepizole versus ethanol in the treatment of acute methanol poisoning: Comparison of clinical effectiveness in a mass poisoning outbreak

References

• Paasma R, Hovda KE, Tikkerberi A, Jacobsen D. Methanol mass poisoning in Estonia: outbreak in 154 patients. Clin Toxicol 2007; 45:152–157.
   PubMed Web of Science ®Google Scholar
• Hovda KE, Hunderi OH, Tafjord AB, Dunlop O, Rudberg N, Jacobsen D. Methanol outbreak in Norway 2002–2004: epidemiology, clinical features and prognostic signs. J Intern Med 2005; 258:181–190.
   PubMed Web of Science ®Google Scholar
• Zakharov S, Pelclova D, Urban P, Navratil T, Diblik P, Kuthan P, et al. Czech mass methanol outbreak 2012: epidemiology, challenges and clinical features. Clin Toxicol 2014; 52:1013–1024.
   PubMed Web of Science ®Google Scholar
• Hassanian-Moghaddam H, Nikfarjam A, Mirafzal A, Saberinia A, Nasehi AA, Masoumi Asl H, Memaryan N. Methanol mass poisoning in Iran: role of case finding in outbreak management. J Public Health (Oxf) 2014; 37:354–359. doi: 10.1093/pubmed/fdu038. Epub 2014/06/20.
   PubMed Web of Science ®Google Scholar
• Levy P, Hexdall A, Gordon P, Boeriu C, Heller M, Nelson L. Methanol contamination of Romanian home-distilled alcohol. J Toxicol Clin Toxicol 2003; 41:23–28.
   PubMed Web of Science ®Google Scholar
• Ahmad K. Methanol-laced moonshine kills 140 in Kenya. The Lancet 2000; 356:1911.
   PubMed Web of Science ®Google Scholar
• Barceloux DG, Bond GR, Krenzelok EP, Cooper H, Vale JA. American Academy of Clinical Toxicology practice guidelines on the treatment of methanol poisoning. J Toxicol-Clin Toxicol 2002; 40:415–446.
   PubMed Web of Science ®Google Scholar
• Megarbane B, Borron SW, Baud FJ. Current recommendations for treatment of severe toxic alcohol poisonings. Intensive Care Med 2005; 31:189–195.
   PubMed Web of Science ®Google Scholar
• Liesivuori J, Savolainen H. Methanol and formic-acid toxicity - biochemical mechanisms. Pharmacol Toxicol 1991; 69:157–163.
   PubMedGoogle Scholar
• Sejersted OM, Jacobsen D, Ovrebo S, Jansen H. Formate concentrations in plasma from patients poisoned with methanol. Acta Med Scand 1983; 213:105–110.
   PubMed Web of Science ®Google Scholar
• Zakharov S, Nurieva O, Navratil T, Diblik P, Kuthan P, Pelclova D. Acute methanol poisonings: folates administration and visual sequelae. J Appl Biomed 2014; 12:309–316.
   Web of Science ®Google Scholar
• Bezdicek O, Klempir J, Liskova I, Michalec J, Vaneckova M, Seidl Z,. Sequelae of methanol poisoning for cognition. Cesk Slov Neurol N 2014; 77/110:320–325.
   Google Scholar
• Zakharov S, Kurcova I, Navratil T, Salek T, Pelclova D. Is the measurement of serum formate concentration useful in the diagnostics of acute methanol poisoning? A prospective study of 38 patients. Basic Clin Pharmacol Toxicol 2015; 116:445–451. doi: 10.1111/bcpt.12338.
   PubMed Web of Science ®Google Scholar
• Coulter CV, Farquhar CE, McCherry CM, Isbister GK, Dufful SB. Methanol and ethylene glycol acute poisonings – predictors of mortality. Clin Toxicol 2011; 49:900–906.
   PubMed Web of Science ®Google Scholar
• Liu JJ, Daya MR, Carrasquillo O, Kales SN. Prognostic factors in patients with methanol poisoning. J Toxicol Clin Toxicol 1998; 36:175–181.
   PubMed Web of Science ®Google Scholar
• Paasma R, Hovda KE, Hassanian-Moghaddam H, Brahmi N, Afshari R, Sandvik L, Jacobsen D. Risk factors related to poor outcome after methanol poisoning and the relation between outcome and antidotes -- a multicenter study. Clin Toxicol 2012; 50:823–831.
   PubMed Web of Science ®Google Scholar
• Hovda KE, Urdal P, Jacobsen D. Increased serum formate in the diagnosis of methanol poisoning. J Anal Toxicol 2005; 29:586–588.
   PubMed Web of Science ®Google Scholar
• Sanaei-Zadeh H, Esfeh SK, Zamani N, Jamshidi F, Shadnia S. Hyperglycemia is a strong prognostic factor of lethality in methanol poisoning. J Med Toxicol 2011; 7:189–194.
   PubMedGoogle Scholar
• Bergeron R, Cardinal J, Geadah D. Prevention of methanol toxicity by ethanol therapy. N Engl J Med 1982; 307:1528.
   PubMed Web of Science ®Google Scholar
• Hantson P, Wittebole X, Haufroid V. Ethanol therapy for methanol poisoning: duration and problems. Eur J Emerg Med 2002; 9:278–279.
   PubMedGoogle Scholar
• Jacobsen D, Jansen H, Wiik-Larsen E, Bredesen JE, Halvorsen S. Studies on methanol poisoning. Acta Med Scand 1982; 212:5–10.
   PubMed Web of Science ®Google Scholar
• Burns MJ, Graudins A, Aaron CK, McMartin K, Brent J. Treatment of methanol poisoning with intravenous 4-methylpyrazole. Ann Emerg Med 1997; 30:829–832.
   PubMed Web of Science ®Google Scholar
• Bekka R, Borron SW, Astier A, Sandouk P, Bismuth C, Baud FJ. Treatment of methanol and isopropanol poisoning with intravenous fomepizole. J Toxicol, Clin Toxicol 2001; 39:59–67.
   PubMed Web of Science ®Google Scholar
• Brent J, McMartin K, Phillips S, Aaron C, Kulig K. Fomepizole for the treatment of methanol poisoning. N Engl J Med 2001; 344:424–429.
   PubMed Web of Science ®Google Scholar
• Zakharov S, Navratil T, Pelclova D. Fomepizole in the treatment of acute methanol poisonings: experience from the Czech mass methanol outbreak 2012–2013. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2014; 158:641–649.
   PubMed Web of Science ®Google Scholar
• WHO. 18th Model List of Essential Medicines 2013; 2014. Available from: http://www.who.int/medicines/publications/essentialmedicines/18th_EML_Final_web_8Jul13.pdf?ua = 1. (Last accessed on February 20, 2014)
   Google Scholar
• Brent J. Fomepizole for ethylene glycol and methanol poisoning. N Engl J Med 2009; 360:2216–2223.
   PubMed Web of Science ®Google Scholar
• Brent J. Fomepizole for the treatment of pediatric ethylene and diethylene glycol, butoxyethanol, and methanol poisonings. Clin Toxicol 2010; 48:401–406.
   PubMed Web of Science ®Google Scholar
• Hovda KE, Jacobsen D. Expert opinion: fomepizole may ameliorate the need for hemodialysis in methanol poisoning. Hum Exp Toxicol 2008; 27:539–546.
   PubMed Web of Science ®Google Scholar
• Megarbane B, Borron SW, Trout H, Hantson P, Jaeger A, Krencker E, et al. Treatment of acute methanol poisoning with fomepizole. Intensive Care Med 2001; 27:1370–1378.
   PubMed Web of Science ®Google Scholar
• Beatty L, Green R, Magee K, Zed P. A systematic review of ethanol and fomepizole use in toxic alcohol ingestions. Emergen Med Int 2013; 2013:14.
   Google Scholar
• Persson H, Sjöberg G, Haines J, Pronczuk de Garbino J. Poisoning severity score: grading of acute poisoning. J Toxicol - Clin Toxicol 1998; 36:205–213.
   PubMed Web of Science ®Google Scholar
• Paasma R, Hovda KE, Jacobsen D. Methanol poisoning and long term sequelae - a six years follow-up after a large methanol outbreak. BMC Clin Pharmacol 2009; 9:5.
   PubMedGoogle Scholar
• Lepik KJ, Levy AR, Sobolev BG, Purssell RA, DeWitt CR, Erhardt GD, et al. Adverse drug events associated with the antidotes for methanol and ethylene glycol poisoning: a comparison of ethanol and fomepizole. Ann Emerg Med 2009; 53:439–450.
   PubMed Web of Science ®Google Scholar
• Lepik KJ, Brubacher JR, Dewitt CR, Lam GS, Lawson EJ, Erhardt GD, et al. Bradycardia and hypotension associated with fomepizole infusion during hemodialysis. Clin Toxicol 2008; 46: 570–573.
   Web of Science ®Google Scholar
• Benitez JG, Swanson-Bierman B, Krenzelok EP. Nystagmus secondary to fomepizole administration in a pediatric patient. Clin Toxicol 2000; 38:795–798.
   Web of Science ®Google Scholar