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ArticlesResearch

Retrograde transport of a traditional Chinese medicine, α-trichosanthin, and its selective neural toxicity

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Pages 876-883 | Received 05 Jul 2008, Accepted 05 Aug 2009, Published online: 23 Oct 2009

References

  • Shaw PC, Lee KM, Wong KB. Recent advances in trichosanthin, a ribosome-inactivating protein with multiple pharmacological properties. Toxicon 2005; 45:683–689.
  • Casellas P, Dussossoy D, Falasca AI, Barbieri L, Guillemot JC, Ferrara P, Bolognesi A, Cenini P, Stripe F. Trichokirin, a ribosome-inactivating protein from the seeds of Trichosanthes kirilowii Maximowicz. Purification, partial characterization and use for preparation of immunotoxins. Eur J Biochem 1988; 176:581–588.
  • May MJ, Hartley MR, Roberts LM, Krieg PA, Osborn RW, Lord JM. Ribosome inactivation by ricin A chain: a sensitive method to assess the activity of wild-type and mutant polypeptides. EMBO J 1989; 8:301–308.
  • Ko WH, Wong CC, Yeung HW, Tam SC. Modulation of trichosanthin antigenicity by coupling to dextran. Biochem Int 1992; 28:643–650.
  • Zhang JS, Liu WY. The mechanism of action of trichosanthin on eukaryotic ribosomes-RNA N-glycosidase activity of the cytotoxin. Nucleic Acids Res 1992; 20:1271–1275.
  • Wong KB, Ke YB, Dong YC, Li XB, Guo YW, Yeung HW, Shaw PC. Structure/function relationship study of Gln156, Glu160 and Glu189 in the active site of trichosanthin. Eur J Biochem 1994; 221:787–791.
  • Tsao SW, Ng TB, Yeung HW. Toxicities of trichosanthin and alpha-momorcharin, abortifacient proteins from Chinese medicinal plants, on cultured tumor cell lines. Toxicon 1990; 28:1183–1192.
  • Ng TB, Chan WY, Sze LY, Yeung HW. Trichosanthin induces atresia of ovarian follicles and inhibits steroidogenesis in gonadotropin-primed immature mice. Gen Pharmacol 1991; 22:847–849.
  • Byers VS, Levin AS, Malvino A, Waites L, Robins RA, Baldwin RW. A phase II study of effect of addition of trichosanthin to zidovudine in patients with HIV disease and failing antiretroviral agents. AIDS Res Hum Retroviruses 1994; 10:413–420.
  • Zheng YT, Zhang WF, Ben KL, Wang JH. In vitro immunotoxicity and cytotoxicity of trichosanthin against human normal immunocytes and leukemia-lymphoma cells. Immunopharmacol Immunotoxicol 1995; 17:69–79.
  • Chao PH, Yang Y. The effect of trichosanthin in treatment of ectopic pregnancy. Zhejiang Prac Med 2008; 6:456–7.
  • Sha O, Kwong WH, Pang Cho EY, Yew TWD, Ng TB. Different neuronal toxicity of single-chain ribosome-inactivating proteins on the rat retina. Toxicon 2008; 51:45–53.
  • Johannes L, Popoff V. Tracing the retrograde route in protein trafficking. Cell 2008; 135:1175–1187.
  • Schwab M, Landis S. Membrane properties of cultured rat sympathetic neurons: morphological studies of adrenergic and cholinergic differentiation. Dev Biol 1981; 84:67–78.
  • England JD, Asbury AK, Rhee EK, Summer AJ. Lethal retrograde axoplasmic transport of doxorubicin (adriamycin) to motor neurons. A toxic motor neuronopathy. Brain 1988; 111:915–926.
  • Arvidson B. A review of axonal transport of metals. Toxicol 1994; 88:1–14.
  • Harting JK, Huerta MF, Hashikawa T, Van Lieshout DP. Projection of the mammalian superior colliculus upon the dorsal lateral geniculate nucleus: organization of tectogeniculate pathways in nineteen species. J Comp Neurol 1991; 304:275–306.
  • Middleton FA, Strick PL. Cerebellar output channels. Int Rev Neurobiol 1997; 41:61–82.
  • O'Brien RAD, Ostberg AJC, Vrbová G. Observations on the elimination of polyneuronal innervation in developing mammalian skeletal muscle. J Physiol 1978; 282:571–582.
  • Melville S, Sherburn TE, Coggeshall RE. Preservation of sensory cells by placing stumps of transected nerve in an impermeable tube. Exp Neurol 1989; 105:311–315.
  • Streit WJ. An improved staining method for rat microglial cells using the lectin from Griffonia simplicifolia (GSA I-B4). J Histochem Cytochem 1990; 38:1683–1686.
  • Shu SY, Ju G, Fan LZ. The glucose oxidase-DAB-nickel method in peroxidase histochemistry of the nervous system. Neurosci Lett 1988; 85:169–171.
  • Stone J, Dreher Z. Relationship between astrocytes, ganglion cells and vasculature of the retina. J Comp neurol 1987; 255:35–59.
  • Harper CG, Gonatas JO, Mizutani T, Gonatas NK. Retrograde transport and effects of toxic ricin in the autonomic nervous system. Lab Invest 1980; 42:396–404.
  • Wiley RG, Oeltmann TN. Anatomically selective peripheral nerve ablation using intraneural ricin injection. J Neurosci Methods 1986; 17:43–53.
  • Streit WJ, Graeber MB, Kreutzberg GW. Expression of Ia antigen on perivascular and microglial cells after sublethal and lethal motor neuron injury. Exp Neurol 1989; 105:115–126.
  • Ling EA, Wen CY, Shieh JY, Yick TY, Leong SK. Neuroglial response to neuron injury. A study using intraneural injection of ricinus communis agglutinin-60. J Anat 1989; 164:201–213.
  • Streit WJ, Kreutzberg GW. Response of endogenous glial cells to motor neuron degeneration induced by toxic ricin. J Comp Neurol 1988; 268:248–263.
  • Currà A, Berardelli A. Do the unintended actions of botulinum toxin at distant sites have clinical implications?. Neurology 2009; 72:1095–1099.
  • Dodd J, Jahr CE, Hamilton PN, Health MJS, Matthew WD, Jessell TM. Cytochemical and physiological properties of sensory and dorsal horn neurons that transmit cutaneous sensation. Cold Spring Harbour Symp Quant Biol 1983; 48:685–695.
  • Himes BT, Tessler A. Death of some dorsal root ganglion neurons and plasticity of others following sciatic nerve section in adult and neonatal rats. J Comp Neurol 1989; 284:215–230.
  • Schmalbruch H. Fiber composition of the rat sciatic nerve. Anat Rec 1986; 215:71–81.
  • Nogradi A, Vrbová G. The use of a neurotoxic lectin, volkensin, to induce loss of identified motoneuron pools. Neuroscience 1992; 50:975–986.
  • Beswetherick JT, Lane PA, Allt G. Schwann cell endocytosis: a role in nerve regeneration?. Neuropathol Appl Neurobiol 1992; 18:395–407.
  • Yawo H, Kuno M. How a nerve fiber repairs its cut end: involvement of phospholipase A2. Science 1983; 222:1351–1353.
  • Eddleman CS, Ballinger ML, Smyers ME, Godell CM, Fishman HM, Bittner GD. Repair of plasmalemmal lesions by vesicles. Proc Natl Acad Sci USA 1997; 94:4745–4750.
  • Godell CM, Smyers ME, Eddleman CS, Calpain activity promotes the sealing of severed giant axons. Proc Natl Acad Sci USA 1997; 94:4751–4756.
  • Xie XY, Barrett JN. Membrane resealing in cultured rat septal neurons after neurite transection: evidence for enhancement by Ca(2+)-triggered protease activity and cytoskeletal disassembly. J Neurosci 1991; 11:3257–3267.
  • Gutmann E, Gutmann L, Medawar PB, Young JZ. The rate of regeneration of nerve. J Exp Biol 1942; 19:14–44.
  • Young JZ. The functional repair of nervous tissue. Physiol Rev 1942; 22:318–374.
  • Zelena J, Lubinska L, Gutmann E. Accumulation of organelles at the ends of interrupted axons. Z Zellforsch Mikrosk Anat 1968; 91:200–219.
  • Olsson Y, Kristensson K. The perineurium as a diffusion barrier to protein tracers following trauma to nerves. Acta Neuropathol (Berl) 1973; 23:105–111.
  • Stirpe F, Barbieri L, Battelli MG, Soria M, Lappi DA. Ribosome-inactivating proteins from plants: present status and future prospects. Biotechnology (NY) 1992; 10:405–412.

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