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Journal of Toxicology: Clinical Toxicology Volume 29, 1991 - Issue 2
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Research Article

Determination Of Serum Acetaminophen In Emergency Toxicology: Evaluation Of Newer Methods: Abbott Tdx and Second Derivative Ultraviolet Spectrophotometry

Leslie E. Edinboro Department of Pathology, Medical College of Virginia Hospitals, Virginia Commonwealth University, Richmond, Virginia
,
George F. Jackson Department of Pathology, Medical College of Virginia Hospitals, Virginia Commonwealth University, Richmond, Virginia
,
Saeed A. Jortani Department of Pathology, Medical College of Virginia Hospitals, Virginia Commonwealth University, Richmond, Virginia
&
Alphonse Poklis Department of Pathology, Medical College of Virginia Hospitals, Virginia Commonwealth University, Richmond, Virginia
Pages 241-255 | Published online: 25 Sep 2008

References

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  • Boyer T D, Rouff SL. Acetaminophen-induced hepatic necrosis and renal failure. JAMA 1971; 218: 440–441
  • Rumack B H, Matthew H. Acetaminophen poisoning and toxicity. Pediatrics 1975; 55: 871–875
  • Peterson R G, Rumack BH. Toxicity of acetaminophen overdose. JACEP 1978; 7: 202–205
  • Hale P W, Poklis A. Evaluation of a modified colorimetric assay for the determination of acetaminophen in serum. J Anal Tox 1983; 7: 249–251
  • Glynn J P, Kendal SE. Paracetamol measurement. Lancet 1975; 8: 1147–1148
  • Prescott LF. The gas-liquid chromatographic estimation of phenacetin and paracetamol in plasma and urine. J Pharm Pharmacol 1971; 23: 111–115
  • Thoma J J, McCoy M, Edward T, Myers N. Acetaminophen an improved gas chromatographic assay. J Anal Tox 1978; 2: 226–228
  • Horvitz R A, Jatlow PI. Determination of acetaminophen concentrations in serum by high-pressure liquid chromatography. Clin Chem 1977; 23: 1596–1598
  • West JC. Rapid HPLC analysis of paracetamol (acetaminophen) in blood and postmortem viscera. J Anal Tox 1981; 5: 118–121
  • Kihuchi H. Determination of serum acetaminophen by fluorescence polarization immunoassay (FPIA). Japan Ther Res (Japan) 1985; 215: 877–882
  • Abbott Laboratories, USA. TDx Toxicology Assays -Acetaminophen. Abbott TDx System Assays II Manual 1984; 22: 1–12
  • Dingeon B, Charvin M A, Quenard M T, Thome H. Multiwavelength analyses of second-derivative spectra for rapid determination of acetaminophen in serum. Clin Chem 1988; 34: 1119–1121

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