124
Views
103
CrossRef citations to date
0
Altmetric
Research Article

Cardiotoxicity More Common in Thioridazine Overdose than with Other Neuroleptics

, &
Pages 199-204 | Published online: 25 Sep 2008

References

  • Mortensen P B, Juel K. Mortality and causes of death in first admitted schizophrenic patients. Br J. Psychiatry 1993; 163: 183–189
  • Montgomery S A, Montgomery D B, Green M, Bullock T, Baldwin D. Pharmacotherapy in the prevention of suicidal behaviour. J Clin Psychopharmacology 1992; 12: 27S–31S
  • Buckley N A, Dawson A H, Whyte I M, McManus P, Ferguson N. Correlations between prescriptions and drugs taken in self-poisoning: Implications for prescribers and drug regulation. Med J Aust 1995, (in press)
  • Johns M W. Self poisoning with barbiturates in England and Wales during 1959-1974. Br Med J 1977; 1: 1128–1130
  • Serfaty M, Masterton G. Fatal poisonings attributed to benzodiazepines in Britain during the 1980s. Br J Psychiatry 1993; 163: 386–393
  • Cassidy S, Henry J. Fatal toxicity of antidepressant drugs in overdose. Br. Med J 1987; 295: 1021–1024
  • Moore M T, Book M H. Sudden death in phenothuiazine treatment. Psychiatr Q 1970; 44: 389–402
  • Fowler N O, McCall D, Chou T C, et al. Electrocardiographic changes and cardiac arrhythmias in patients receiving psychotropic drugs. Am J Cardiol 1976; 37: 223–230
  • Hollister L E, Kosek J C. Sudden death during treatment with phenothiazine derivatives. JAMA 1665; 192: 1035
  • Kahn A, Blum D. Phenothiazines and sudden death syndrome. Pediatrics 1982; 70: 75–78
  • Kelly H G, Kay J E, Laverty S G. Thioridazine HCL (Mellaril): Its effect on the electrocardiogram and a report of two fatalities with electrocardiographic abnormalities. Can Med Assoc J 1963; 89: 546–553
  • Leestma J E, Koening K L. Sudden death and Phenothiazines. Arch Gen Psychiatr 1968; 18: 137
  • Mehtonen O P, Aranko K, Malkonen L, Vapaatalo H. A survey of sudden death associated with the use of antipsychtic or antidepressant drugs: 49 cases in Finland. Acta Psychiart Scand 1991; 84: 58–64
  • McCarron M M, Schulze B W, Walberg C B, Thompson G A, Ansari A. Short acting barbiturate overdosage. Correlation of intoxication score with serum barbiturate concentration. JAMA 1982; 248: 55–61
  • Garson A. How to measure the QT interval-what is normal. Am J Cardiol 1993; 72: 14B–16B
  • Australian Statistics on Medicines. Department of Health. Aust Government Printing Office. 1992; 1994
  • Baselt R C, Cravey R H. Disposition of Toxic Drugs and Chemicals in Man3rd ed. Year Book Medical Publishers, Chicago 1989
  • LeBlaye I, Donatini B, Hall M, Krupp P. Acute overdosage with thioridazine: a review of the available clinical exposure. Vet Hum Toxicol 1993; 35: 147–150
  • Ellenhorn M J, Barceloux D G. Medical Toxicology: Diagnosis and Treatment of Human Poisoning. Elsevier, New York 1988; 805–811
  • Buckley N A, Dawson A H, Whyte I M, Henry D A. Greater toxicity of dothiepin in overdose than of other tricyclic antidepressants. Lancet 1994; 343: 159–162
  • Office of Population Censuses and Surveys. Deaths from poisoning by solid or liquid substances: accidental, suicidal and undetermined whether accidentally taken or purposely inflicted. Series DH4 no 13, HMSO, London 1992, Table 10 1994
  • Keren A, Tzivoni D. Torsades de pointes: prevention and therapy. Cardiovasc Drugs Ther 1991; 5: 509–513
  • Campbell T J. Proarrhythmic actions of antiarrhythmic drugs: a review. Aust N Z J Med 1990; 20: 275–282
  • Aunsholt N A. Prolonged QT interval and hypokalemia caused by haloperidol. Acta Psychiar Scand 1989; 79: 411–412
  • Wilt J L, Minnema A M, Johnson R F, Rosenblum A M. Torsade de pointes associated with the use of intravenous haloperidol. Ann Intern Med 1993; 119: 391–394
  • Zee-Cheng C S, Mueller C E, Seifert C F, et al. Haloperidol and torsades de pointes. Ann Intern Med 1985; 102: 418

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.