56
Views
9
CrossRef citations to date
0
Altmetric
Original Investigations

Low novelty seeking and high self directedness scores in alcohol-dependent patients without comorbid psychiatric disorders homozygous for the A10 allele of the dopamine transporter gene

, , , , , , , & show all
Pages 382-389 | Received 12 Apr 2007, Accepted 25 Oct 2007, Published online: 10 Mar 2010

References

  • Anthenelli RM, Smith TL, Irwin MR, Schuckit MA. A comparative study of criteria for subgrouping alcoholics: the primary/secondary diagnostic scheme versus variations of the type 1/type 2 criteria. Am J Psychiatry 1994; 151: 1468–1474
  • Banoei, MM, Majidizadeh, T, Shirazi, E, , et al. 2007. No association between the DAT1 10-repeat allele and ADHD in the Iranian population. Am J Med Genet B Neuropsychiatr Genet [ Epub ahead of print].
  • Bau CH, Almeida S, Costa FT, et al. DRD4 and DAT1 as modifying genes in alcoholism: interaction with novelty seeking on level of alcohol consumption. Mol Psychiatry 2001; 6: 7–9
  • Borkenau, P, Ostendorf, F. 1993. NEO-Fünf-Faktoren-Inventar (NEO-FFI) nach Costa und McCrae. Göttingen: Hofgrefe.
  • Brookes, KJ, Neale, BM, Sugden, K, Khan, N, Asherson, P, D‘Souza, UM. 2007. Relationship between VNTR polymorphisms of the human dopamine transporter gene and expresseion in post-mortem midbrain tissue. Am J Med Genet B Neuropsychiatr Genet, Epub ahead of print
  • Byerley W, Hoff M, Holik J, Caron MG, Giros B. VNTR polymorphism for the human dopamine transporter gene (DAT1). Hum Mol Genet 1993; 2: 335
  • Choi IG, Kee BS, Son HG, et al. Genetic polymorphisms of alcohol and aldehyde dehydrogenase, dopamine and serotonin transporters in familial and non-familial alcoholism. Eur Neuropsychopharmacol 2006; 16: 123–128
  • Cloninger CR, Svrakic DM. Integrative psychobiological approach to psychiatric assessment and treatment. Psychiatry 1997; 60: 120–141
  • Cook BL, Winokur G, Fowler RC, Liskow BI. Classification of alcoholism with reference to comorbidity. Compr Psychiatry 1994; 35: 165–170
  • Dobashi I, Inada T, Hadano K. Alcoholism and gene polymorphisms related to central dopaminergic transmission in the Japanese population. Psychiatr Genet 1997; 7: 87–91
  • Drago J, Padungchaichot P, Accili D, Fuchs S. Dopamine receptors and dopamine transporter in brain function and addictive behaviors: insights from targeted mouse mutants. Dev Neurosci 1998; 20: 188–203
  • Franke P, Schwab SG, Knapp M, et al. DAT1 gene polymorphism in alcoholism: a family-based association study. Biol Psychiatry 1999; 45: 652–654
  • Gelernter J, Kranzler HR, Satel SL, Rao PA. Genetic association between dopamine transporter protein alleles and cocaine-induced paranoia. Neuropsychopharmacology 1994; 11: 195–200
  • Giros B, Jaber M, Jones SR, Wightman RM, Caron MG. Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature 1996; 379: 606–612
  • Hasin DS, Grant BF. The co-occurrence of DSM-IV alcohol abuse in DSM-IV alcohol dependence. Arch Gen Psychiatry 2004; 61: 891–896
  • Heinz A, Goldman D, Jones DW, et al. Genotype influences in vivo dopamine transporter availability in human striatum. Neuropsychopharmacology 2000; 22: 133–139
  • Holmes J, Payton A, Barrett J, et al. Association of DRD4 in children with ADHD and comorbid conduct problems. Am J Med Gen 2002; 114: 150–153
  • Kim, SJ, Kim, YS, Kim, CH, Lee, HS. 2006a. Lack of association between polymorphisms of the dopamine receptor D4 and dopamine transporter genes and personality traits in a Korean population. Yonsei Med J, 47:787–792.
  • Kim, SJ, Kim, YS, Lee, HS, Kim, SY, Kim, CH. 2006b. An interaction between the serotonin transporter promoter region and dopamine transporter polymorphisms contributes to harm avoidance and reward dependence traits in normal healthy subjects. J Neural Transm, 113:877–886.
  • Knopik VS, Heath AC, Madden PAF, et al. Genetic effects on alcohol dependence risk: re-evaluating the importance of psychiatric and other heritable risk factors. Psychol Med 2004; 34: 1519–1530
  • Köhnke MD, Batra A, Kolb W, et al. Association of the dopamine transporter gene with alcoholism. Alcohol Alcohol 2005; 40: 339–342
  • Kucharska-Mazur J, Parus M, Syrek S, et al. The association between the dopamine transporter and COMT gene polymorphisms and the personality traits measured by the Temperamental and Character Inventory (TCI) and NEO-FFI in healthy volunteers APN Suppl 2004; 3: 25–33
  • Laine TP, Ahonen A, Rasanen P, Tiihonen J. Dopamine transporter density and novelty seeking among alcoholics. J Addict Dis 2001; 20: 91–96
  • Laucht M, Skowronek MH, Becker KS, et al. Interacting effects of the dopamine transporter gene and psychosocial adversity on attention-deficit/hyperactivity disorder symptoms among 15-year-olds from a high-risk community sample. Arch Gen Psychiatry 2007; 64: 585–590
  • Limosin F, Loze JY, Boni C, et al. The A9 allele of the dopamine transporter gene increases the risk of visual hallucinations during alcohol withdrawal in alcohol-dependent women. Neuroscience letters 2004; 362: 91–94
  • Martin ED, Sher KJ. Family history of alcoholism, alcohol use disorders and the five-factor model of personality. J Stud Alcohol 1994; 55: 81–90
  • Mezzich AC, Arria AM, Tarter RE, Moss H, Van Thiel DH. Psychiatric comorbidity in alcoholism: importance of ascertainment source. Alcohol Clin Exp Res 1991; 15: 893–898
  • Mitchell RJ, Howlett S, Earl L, et al. Distribution of the 3′ VNTR polymorphism in the human dopamine transporter gene in world populations. Hum Biol 2000; 72: 295–304
  • Muramatsu T, Higuchi S. Dopamine transporter gene polymorphism and alcoholism. Biochem Biophys Res Commun 1995; 211: 28–32
  • Nakatome M, Honda K, Tun Z, et al. Genetic polymorphism of the 3′ VNTR region of the human dopaminergic function gene DAT1 (human dopamine transporter gene) in the Mongolian population. Hum Biol 1996; 68: 509–515
  • Persico AM, Catalano M. Lack of association between dopamine transporter gene polymorphisms and delusional disorder. Am J Med Genet 1998; 81: 163–165
  • Persico AM, Vandenbergh DJ, Smith SS, Uhl GR. Dopamine transporter gene polymorphisms are not associated with polysubstance abuse. Biol Psychiatry 1993; 34: 265–267
  • Quirk SW, McCormick RA. Personality subtypes, coping styles, symptom correlates, and substances of choice among a cohort of substance abusers. Assessment 1998; 5: 157–169
  • Richter J, Bollow K, Cloninger CR, Przybeck T. Erste Erfahrungen mit der deutschen Version des Temperament- und Verhaltensinventars (TCI-Selbsteinschätzung). Verhaltensther Verhaltenmed 1997; 18: 95–110
  • Samochowiec J, Kucharska-Mazur J, Grzywacz A, et al. Family-based and case-control study of DRD2, DAT, 5HTT, COMT genes polymorphisms in alcohol dependence. Neurosci lett 2006; 410: 1–5
  • Sander T, Harms H, Podschus J, et al. Allelic association of a dopamine transporter gene polymorphism in alcohol dependence with withdrawal seizures or delirium. Biol Psychiatry 1997; 41: 299–304
  • Sano A, Kondoh K, Kakimoto Y, Kondo I. A 40-nucleotide repeat polymorphism in the human dopamine transporter gene. Hum Genet 1993; 91: 405–406
  • Savelieva KV, Caudle WM, Findlay GS, Caron MG, Miller GW. Decreased ethanol preference and consumption in dopamine transporter female knock-out mice. Alcohol Clin Exp Res 2002; 26: 758–764
  • Schmidt LG, Harms H, Kuhn S, Rommelspacher H, Sander T. Modification of alcohol withdrawal by the A9 allele of the dopamine transporter gene. Am J Psychiatry 1998; 155: 474–478
  • Sullivan PF, Fifield WJ, Kennedy MA, Mulder RT, Sellman JD, Joyce PR. Novelty seeking and a dopamine transporter gene polymorphism (DAT1). Biol Psychiatry 1997; 42: 1070–1072
  • Szczepankiewicz A, Dmitrzak-Weglarz M, Skibinska M, et al. Study of dopamine receptors genes polymorphisms in bipolar patients with comorbid alcohol abuse. Alcohol Alcoholism 2007; 42: 70–74
  • Thome J, Weijers HG, Wiesbeck GA, et al. Dopamine D3 receptor gene polymorphism and alcohol dependence: relation to personality rating. Psychiatr Genet 1999; 9: 17–21
  • Tiihonen J, Kuikka J, Bergstrom K, et al. Altered striatal dopamine re-uptake site densities in habitually violent and non-violent alcoholics [see comments]. Nat Med 1995; 1: 654–657
  • Tupala E, Hall H, Bergström K, et al. Dopamine D2/D3-receptor and transporter densities in nucleus accumbens and amygdala of type 1 and 2 alcoholics. Mol Psychiatry 2001; 6: 261–267
  • Ueno S, Nakamura M, Mikami M, et al. Identification of a novel polymorphism of the human dopamine transporter (DAT1) gene and the significant association with alcoholism. Mol Psychiatry 1999; 4: 552–557
  • Van Gestel S, Forsgren T, Claes S, et al. Epistatic effect of genes from the dopamine and serotonin systems on the temperament traits of Novelty Seeking and Harm Avoidance. Mol Psychiatry 2002; 7: 448–450
  • Vandenbergh DJ, Persico AM, Hawkins AL, et al. Human dopamine transporter gene (DAT1) maps to chromosome 5p15.3 and displays a VNTR. Genomics 1992; 14: 1104–1106
  • Waldman ID, Rowe DC, Abramowitz A, et al. Association and linkage of the dopamine transporter gene and attention- deficit hyperactivity disorder in children: heterogeneity owing to diagnostic subtype and severity. Am J Hum Genet 1998; 63: 1767–1776
  • Wernicke C, Smolka M, Gallinat J, Winterer G, Schmidt LG, Rommelspacher H. Evidence for the importance of the human dopamine transporter gene for withdrawal symptomatology of alcoholics in a german population. Neurosci Lett 2002; 333: 45–48
  • Winsberg BG, Comings DE. Association of the dopamine transporter gene (DAT1) with poor methylphenidate response [see comments]. J Am Acad Child Adolesc Psychiatry 1999; 38: 1474–1477
  • Wittchen HU. Reliability and validity studies of the WHO – Composite International Diagnostic Interview (CIDI): a critical review. J Psychiatr Res 1994; 28: 57–84
  • Wittchen, HU, Zaudig, M, Fydrich, T. 1997. SCID Strukturiertes klinisches interview für DSM-IV Achse I und II, Handanweisung Second edition. Weinheim; Hogrefe.
  • Yang B, Chan RC, Jing J, Li T, Sham P, Chen RY. A meta-analysis of association studies between the 10-repeat allele of a VNTR polymorphism in the 3′-UTR of dopamine transporter gene and attention deficit hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet 2007; 144: 541–550

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.