Neural bases of atypical emotional face processing in autism: A meta-analysis of fMRI studies

References

• Adolphs R. 2008. Fear, faces, and the human amygdala. Curr Opin Neurobiol 18:166–172.
   PubMed Web of Science ®Google Scholar
• Adolphs R. 2010. Conceptual challenges and directions for social neuroscience. Neuron 65:752–767.
   PubMed Web of Science ®Google Scholar
• Andrzejewski ME, McKee BL, Baldwin AE, Burns L, Hernandez P. 2013. The clinical relevance of neuroplasticity in corticostriatal networks during operant learning. Neurosci Biobehav Rev 37:2071–2080.
   PubMed Web of Science ®Google Scholar
• Aoki Y, Inokuchi R, Nakao T, Yamasue H. 2013a. Neural bases of antisocial behavior: a voxel-based meta-analysis. Soc Cogn Affect Neurosci. Online publication.
   Google Scholar
• Aoki Y, Inokuchi R, Suwa H, Aoki A. 2013b. Age-related change of neurochemical abnormality in attention-deficit hyperactivity disorder: a meta-analysis. Neurosci Biobehav Rev 37: 1692–1701.
   PubMed Web of Science ®Google Scholar
• Aoki Y, Abe O, Nippashi Y, Yamasue H. 2013c. Comparison of white matter integrity between autism spectrum disorder subjects and typically developing individuals: a meta-analysis of diffusion tensor imaging tractography studies. Mol Autism 4:25.
   PubMed Web of Science ®Google Scholar
• Aoki Y, Kasai K, Yamasue H. 2012a. Age-related change in brain metabolite abnormalities in autism: a meta-analysis of proton magnetic resonance spectroscopy studies. Transl Psychiatry 2:e69.
   Web of Science ®Google Scholar
• Aoki Y, Aoki A, Suwa H. 2012b. Reduction of N-acetylaspartate in the medial prefrontal cortex correlated with symptom severity in obsessive-compulsive disorder: meta-analyses of (1)H-MRS studies. Transl Psychiatry 2:e153.
   Web of Science ®Google Scholar
• Ashwin C, Baron-Cohen S, Wheelwright S, O’Riordan M, Bullmore E. 2007. Differential activation of the amygdala and the ‘social brain’ during fearful face-processing in Asperger Syndrome. Neuropsychologia 45:2–14.
   PubMed Web of Science ®Google Scholar
• American Psychiatric Association. 2013. Diagnostic and statistical manual of mental disorders. 5th ed. American Psychiatric Publishing.
   Google Scholar
• Bellani M, Fornasari L, Chittaro L, Brambilla P. 2011. Virtual reality in autism: state of the art. Epidemiol Psychiatr Sci 20:235–238.
   PubMed Web of Science ®Google Scholar
• Bolte S, Hubl D, Feineis-Matthews S, Prvulovic D, Dierks T, Poustka F. 2006. Facial affect recognition training in autism: can we animate the fusiform gyrus? Behav Neurosci 120: 211–216.
   PubMed Web of Science ®Google Scholar
• Bora E, Fornito A, Yucel M, Pantelis C. 2011. The effects of gender on grey matter abnormalities in major psychoses: a comparative voxelwise meta-analysis of schizophrenia and bipolar disorder. Psychol Med 11:1–13.
   Google Scholar
• Bornstein AM, Daw ND. 2011. Multiplicity of control in the basal ganglia: computational roles of striatal subregions. Curr Opin Neurobiol 21:374–380.
   PubMed Web of Science ®Google Scholar
• Brambilla P, Hardan AY, di Nemi SU, Caverzasi E, Soares JC, Perez J, et al. 2004. The functional neuroanatomy of autism. Funct Neurol 19:9–17.
   PubMed Web of Science ®Google Scholar
• Cauda F, Geda E, Sacco K, D’Agata F, Duca S, Geminiani G, et al. 2011. Grey matter abnormality in autism spectrum disorder: an activation likelihood estimation meta-analysis study. J Neurol Neurosurg Psychiatry 82:1304–1313.
   PubMed Web of Science ®Google Scholar
• Celani G, Battacchi MW, Arcidiacono L. 1999. The understanding of the emotional meaning of facial expressions in people with autism. J Autism Dev Disord 29:57–66.
   PubMed Web of Science ®Google Scholar
• Corbett BA, Carmean V, Ravizza S, Wendelken C, Henry ML, Carter C, et al. 2009. A functional and structural study of emotion and face processing in children with autism. Psychiatry Res 173:196–205.
   PubMed Web of Science ®Google Scholar
• Cortese S, Kelly C, Chabernaud C, Proal E, Di Martino A, Milham MP, et al. 2012. Toward systems neuroscience of ADHD: a meta-analysis of 55 fMRI studies. Am J Psychiatry 169:1038–1055.
   PubMed Web of Science ®Google Scholar
• Critchley H, Daly E, Bullmore E, Williams S, Van Amelsvoort T, Robertson D, et al. 2000. The functional neuroanatomy of social behaviour: changes in cerebral blood flow when people with autistic disorder process facial expressions. Brain 123: 2203–2212.
   PubMed Web of Science ®Google Scholar
• Dalgleish T. 2004. The emotional brain. Nat Rev Neurosci 5: 583–589.
   PubMed Web of Science ®Google Scholar
• Dalton KM, Nacewicz BM, Johnstone T, Schaefer HS, Gernsbacher MA, Goldsmith HH, et al. 2005. Gaze fixation and the neural circuitry of face processing in autism. Nat Neurosci 8:519–526.
   PubMed Web of Science ®Google Scholar
• Deeley Q, Daly EM, Surguladze S, Page L, Toal F, Robertson D, et al. 2007. An event related functional magnetic resonance imaging study of facial emotion processing in Asperger syndrome. Biol Psychiatry 62:207–217.
   PubMed Web of Science ®Google Scholar
• Delvecchio G, Sugranyes G, Frangou S. 2013. Evidence of diagnostic specificity in the neural correlates of facial affect processing in bipolar disorder and schizophrenia: a meta-analysis of functional imaging studies. Psychol Med 43:553–569.
   PubMed Web of Science ®Google Scholar
• Di Martino A, Ross K, Uddin LQ, Sklar AB, Castellanos FX, Milham MP. 2009. Functional brain correlates of social and nonsocial processes in autism spectrum disorders: an activation likelihood estimation meta-analysis. Biol Psychiatry 65:63–74.
   PubMed Web of Science ®Google Scholar
• Dickstein DP, Pescosolido MF, Reidy BL, Galvan T, Kim KL, Seymour KE, et al. 2013. Developmental meta-analysis of the functional neural correlates of autism spectrum disorders. J Am Acad Child Adolesc Psychiatry 52:279–289, e16.
   PubMed Web of Science ®Google Scholar
• Fombonne E. 2003. The prevalence of autism. J Am Med Asoc 289:87–89.
   PubMed Web of Science ®Google Scholar
• Fusar-Poli P. 2012. Voxel-wise meta-analysis of fMRI studies in patients at clinical high risk for psychosis. J Psychiatry Neurosci 37:106–112.
   PubMed Web of Science ®Google Scholar
• Gordon I, Vander Wyk BC, Bennett RH, Cordeaux C, Lucas MV, Eilbott JA, et al. 2013. Oxytocin enhances brain function in children with autism. Proc Natl Acad Sci USA 110: 20953–20958.
   PubMed Web of Science ®Google Scholar
• Greimel E, Schulte-Ruther M, Kircher T, Kamp-Becker I, Remschmidt H, Fink GR, et al. 2010. Neural mechanisms of empathy in adolescents with autism spectrum disorder and their fathers. Neuroimage 49:1055–1065.
   PubMed Web of Science ®Google Scholar
• Happe F, Ronald A, Plomin R. 2006. Time to give up on a single explanation for autism. Nat Neurosci 9:1218–1220.
   PubMed Web of Science ®Google Scholar
• Harms MB, Martin A, Wallace GL. 2010. Facial emotion recognition in autism spectrum disorders: a review of behavioral and neuroimaging studies. Neuropsychol Rev 20:290–322.
   PubMed Web of Science ®Google Scholar
• Hart H, Radua J, Mataix-Cols D, Rubia K. 2012. Meta-analysis of fMRI studies of timing in attention-deficit hyperactivity disorder (ADHD). Neurosci Biobehav Rev 36:2248–2256.
   PubMed Web of Science ®Google Scholar
• Hart H, Radua J, Nakao T, Mataix-Cols D, Rubia K. 2013. Meta-analysis of functional magnetic resonance imaging studies of inhibition and attention in attention-deficit/hyperactivity disorder: exploring task-specific, stimulant medication, and age effects. J Am Med Assoc Psychiatry 70:185–198.
   Google Scholar
• Haznedar MM, Buchsbaum MS, Hazlett EA, LiCalzi EM, Cartwright C, Hollander E. 2006. Volumetric analysis and three-dimensional glucose metabolic mapping of the striatum and thalamus in patients with autism spectrum disorders. Am J Psychiatry 163:1252–1263.
   PubMed Web of Science ®Google Scholar
• Horder J, Lavender T, Mendez MA, O’Gorman R, Daly E, Craig MC, et al. 2013. Reduced subcortical glutamate/glutamine in adults with autism spectrum disorders: a [(1)H]MRS study. Transl Psychiatry 3:e279.
   Web of Science ®Google Scholar
• Hubl D, Bölte S, Feineis-Matthews S, Lanfermann H, Federspiel A, Strik W, et al. 2003. Functional imbalance of visual pathways indicates alternative face processing strategies in autism. Neurology 61:1232–1237.
   PubMed Web of Science ®Google Scholar
• Ishitobi M, Kosaka H, Omori M, Matsumura Y, Munesue T, Mizukami K, et al. 2011. Differential amygdala response to lower face in patients with autistic spectrum disorders: An fMRI study. Res Autism Spectr Disord 5:910–919.
   Web of Science ®Google Scholar
• Kim YS, Leventhal BL, Koh YJ, Fombonne E, Laska E, Lim EC, et al. 2011. Prevalence of autism spectrum disorders in a total population sample. Am J Psychiatry 168:904–912.
   PubMed Web of Science ®Google Scholar
• Kleinhans NM, Richards T, Johnson LC, Weaver KE, Greenson J, Dawson G, et al. 2011. fMRI evidence of neural abnormalities in the subcortical face processing system in ASD. Neuroimage 54:697–704.
   PubMed Web of Science ®Google Scholar
• Langen M, Bos D, Noordermeer SD, Nederveen H, van Engeland H, Durston S. 2013. Changes in the development of striatum are involved in repetitive behavior in autism. Biol Psychiatry. Online publication.
   Google Scholar
• Langen M, Durston S, Kas MJ, van Engeland H, Staal WG. 2011a. The neurobiology of repetitive behavior: … and men. Neurosci Biobehav Rev 35:356–365.
   PubMed Web of Science ®Google Scholar
• Langen M, Kas MJ, Staal WG, van Engeland H, Durston S. 2011b. The neurobiology of repetitive behavior: of mice. Neurosci Biobehav Rev 35:345–355.
   PubMed Web of Science ®Google Scholar
• Lemonnier E, Degrez C, Phelep M, Tyzio R, Josse F, Grandgeorge M, et al. 2012. A randomised controlled trial of bumetanide in the treatment of autism in children. Transl Psychiatry 2:e202.
   PubMed Web of Science ®Google Scholar
• Liljeholm M, O’Doherty JP. 2012. Contributions of the striatum to learning, motivation, and performance: an associative account. Trends Cogn Sci 16:467–475.
   PubMed Web of Science ®Google Scholar
• Lin IF, Kashino M, Ohta H, Yamada T, Tani M, Watanabe H, et al. 2014. The effect of intranasal oxytocin versus placebo treatment on the autonomic responses to human sounds in autism: a single-blind, randomized, placebo-controlled, crossover design study. Mol Autism 5:20.
   PubMed Web of Science ®Google Scholar
• Lynch CJ, Uddin LQ, Supekar K, Khouzam A, Phillips J, Menon V. 2013. Default mode network in childhood autism: posteromedial cortex heterogeneity and relationship with social deficits. Biol Psychiatry 74:212–219.
   PubMed Web of Science ®Google Scholar
• Moher D, Cook DJ, Eastwood S, Olkin I, Rennie D, Stroup DF. 1999. Improving the quality of reports of meta-analyses of randomised controlled trials: the QUOROM statement. Quality of Reporting of Meta-analyses. Lancet 354:1896–1900.
   PubMed Web of Science ®Google Scholar
• Morita T, Kosaka H, Saito DN, Ishitobi M, Munesue T, Itakura S, et al. 2011. Emotional responses associated with self-face processing in individuals with autism spectrum disorders: An fMRI study. Soc Neurosci 7:223–239.
   PubMed Web of Science ®Google Scholar
• Nair A, Treiber JM, Shukla DK, Shih P, Muller RA. 2013. Impaired thalamocortical connectivity in autism spectrum disorder: a study of functional and anatomical connectivity. Brain 136:1942–1955.
   PubMed Web of Science ®Google Scholar
• Nakao T, Radua J, Rubia K, Mataix-Cols D. 2011. Gray matter volume abnormalities in ADHD: voxel-based meta-analysis exploring the effects of age and stimulant medication. Am J Psychiatry 168:1154–1163.
   PubMed Web of Science ®Google Scholar
• Norbury R, Selvaraj S, Taylor MJ, Harmer C, Cowen PJ. 2010. Increased neural response to fear in patients recovered from depression: a 3T functional magnetic resonance imaging study. Psychol Med 40:425–432.
   PubMed Web of Science ®Google Scholar
• Pelphrey KA, Carter EJ. 2008. Charting the typical and atypical development of the social brain. Dev Psychopathol 20: 1081–1102.
   PubMed Web of Science ®Google Scholar
• Pelphrey KA, Morris JP, McCarthy G, Labar KS. 2007. Perception of dynamic changes in facial affect and identity in autism. Soc Cogn Affect Neurosci 2:140–149.
   PubMed Web of Science ®Google Scholar
• Pelphrey KA, Sasson NJ, Reznick JS, Paul G, Goldman BD, Piven J. 2002. Visual scanning of faces in autism. J Autism Deve Disord 32:249–261.
   PubMed Web of Science ®Google Scholar
• Perlman SB, Hudac CM, Pegors T, Minshew NJ, Pelphrey KA. 2011. Experimental manipulation of face-evoked activity in the fusiform gyrus of individuals with autism. Soc Neurosci 6: 22–30.
   PubMed Web of Science ®Google Scholar
• Peron J, Fruhholz S, Verin M, Grandjean D. 2013. Subthalamic nucleus: a key structure for emotional component synchronization in humans. Neurosci Biobehav Rev 37:358–373.
   PubMed Web of Science ®Google Scholar
• Philip RC, Dauvermann MR, Whalley HC, Baynham K, Lawrie SM, Stanfield AC. 2012. A systematic review and meta-analysis of the fMRI investigation of autism spectrum disorders. Neurosci Biobehav Rev 36:901–942.
   PubMed Web of Science ®Google Scholar
• Radua J, Borgwardt S, Crescini A, Mataix-Cols D, Meyer-Lindenberg A, McGuire PK, et al. 2012. Multimodal meta-analysis of structural and functional brain changes in first episode psychosis and the effects of antipsychotic medication. Neurosci Biobehav Rev 36:2325–2333.
   PubMed Web of Science ®Google Scholar
• Radua J, Mataix-Cols D. 2009. Voxel-wise meta-analysis of grey matter changes in obsessive-compulsive disorder. Br J Psychiatry 195:393–402.
   PubMed Web of Science ®Google Scholar
• Radua J, Mataix-Cols D, Phillips ML, El-Hage W, Kronhaus DM, Cardoner N, et al. 2012. A new meta-analytic method for neuroimaging studies that combines reported peak coordinates and statistical parametric maps. Eur Psychiatry 27:605–611.
   PubMed Web of Science ®Google Scholar
• Radua J, van den Heuvel OA, Surguladze S, Mataix-Cols D. 2010. Meta-analytical comparison of voxel-based morphometry studies in obsessive-compulsive disorder vs other anxiety disorders. Arch Gen Psychiatry 67:701–711.
   PubMed Web of Science ®Google Scholar
• Rahko JS, Paakki JJ, Starck TH, Nikkinen J, Pauls DL, Katsyri JV, et al. 2012. Valence scaling of dynamic facial expressions is altered in high-functioning subjects with autism spectrum disorders: an fMRI study. J Autism Dev Disord 42:1011–1024.
   PubMed Web of Science ®Google Scholar
• Roland PE, Levin B, Kawashima R, Åkerman S. 1993. Three-dimensional analysis of clustered voxels in 15O-butanol brain activation images. Human Brain Mapping 1:3–19.
   Google Scholar
• Rudie JD, Hernandez LM, Brown JA, Beck-Pancer D, Colich NL, Gorrindo P, et al. 2012. Autism-associated promoter variant in MET impacts functional and structural brain networks. Neuron 75:904–915.
   PubMed Web of Science ®Google Scholar
• Sears LL, Vest C, Mohamed S, Bailey J, Ranson BJ, Piven J. 1999. An MRI study of the basal ganglia in autism. Prog Neuropsychopharmacol Biol Psychiatry 23:613–624.
   PubMed Web of Science ®Google Scholar
• Sigman MD, Kasari C, Kwon JH, Yirmiya N. 1992. Responses to the negative emotions of others by autistic, mentally retarded, and normal children. Child Dev 63:796–807.
   PubMed Web of Science ®Google Scholar
• Sonuga-Barke EJ1, Brandeis D, Cortese S, Daley D, Ferrin M, Holtmann M et al. 2013. Nonpharmacological interventions for ADHD: systematic review and meta-analyses of randomized controlled trials of dietary and psychological treatments. Am J Psychiatry 170:275–289.
   PubMed Web of Science ®Google Scholar
• Tamietto M, de Gelder B. 2010. Neural bases of the non-conscious perception of emotional signals. Nat Rev Neurosci 11: 697–709.
   PubMed Web of Science ®Google Scholar
• Tantam D, Monaghan L, Nicholson H, Stirling J. 1989. Autistic children's ability to interpret faces: a research note. J Child Psychol Psychiatry 30:623–630.
   PubMed Web of Science ®Google Scholar
• Tsatsanis KD, Rourke BP, Klin A, Volkmar FR, Cicchetti D, Schultz RT. 2003. Reduced thalamic volume in high-functioning individuals with autism. Biol Psychiatry 53:121–129.
   PubMed Web of Science ®Google Scholar
• Via E, Radua J, Cardoner N, Happe F, Mataix-Cols D. 2011. Meta-analysis of gray matter abnormalities in autism spectrum disorder: should Asperger disorder be subsumed under a broader umbrella of autistic spectrum disorder? Arch Gen Psychiatry 68:409–418.
   PubMed Web of Science ®Google Scholar
• Weigelt S, Koldewyn K, Kanwisher N. 2012. Face identity recognition in autism spectrum disorders: a review of behavioral studies. Neurosci Biobehav Rev 36:1060–1084.
   PubMed Web of Science ®Google Scholar
• Weng SJ, Carrasco M, Swartz JR, Wiggins JL, Kurapati N, Liberzon I, et al. 2011. Neural activation to emotional faces in adolescents with autism spectrum disorders. J Child Psychol Psychiatry 52:296–305.
   PubMed Web of Science ®Google Scholar
• Wicker B, Fonlupt P, Hubert B, Tardif C, Gepner B, Deruelle C. 2008. Abnormal cerebral effective connectivity during explicit emotional processing in adults with autism spectrum disorder. Soc Cogn Affect Neurosci 3:135–143.
   PubMed Web of Science ®Google Scholar
• Yamasue H, Yee JR, Hurlemann R, Rilling JK, Chen FS, Meyer-Lindenberg A, et al. 2012. Integrative approaches utilizing oxytocin to enhance prosocial behavior: from animal and human social behavior to autistic social dysfunction. J Neurosci 32:14109–14117.
   PubMed Web of Science ®Google Scholar
• Yirmiya N, Sigman MD, Kasari C, Mundy P. 1992. Empathy and cognition in high-functioning children with autism. Child Dev 63:150–160.
   PubMed Web of Science ®Google Scholar