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Original Article

On the Specific Effectiveness, and Under-Valuing, of Pharmacological Treatments for Addiction: A Comparison of Methadone, Naltrexone and Disulfiram with Psychosocial Interventions

Pages 297-313 | Published online: 11 Jul 2009

References

  • Abed R. T., Neira-Munoz E. A survey of general practitioners' opinion and attitude to drug addicts and addiction. British Journal of Addiction 1990; 85: 131–136
  • Alcoholics Anonymous. Living Sober, p. 60. London. Jupiter. Andersen, M. P. (1992) Lack of bioequivalence between disulfiram formulations, exemplified by a tablet/effervescent tablet study. Acta Psychiatrica Scandinavica 1975; 86: 31–35
  • Anglin M. D., McGlothlin W. Outcome of narcotic addict treatment in California. Drug abuse treatment evaluation: strategies progress and prospects: 106–128, F. Tims, J. Lundford. NIDA, Rockville, MD 1994, N1DA Research Monograph 51, DHHS Publication no. (ADM) 84–1349
  • Atkinson R. L., Drake Berke L. K., et al. Effects of long term therapy with naltrexone on body weight in obesity. Clinical Pharmacology and Therapeutics 1985; 38: 419–22
  • Azrin N. H., Sissons R. W., Mayer S. R., Godley M. Alcoholism treatment by disulfiram and community reinforcement therapy. Journal of Behaviour Therapy & Experimental Psychiatry 1982; 13: 105–12
  • Azrin N. H. Disulfiram and behaviour therapy: a social-biochemical model of alcohol abuse and treatment. Treatment Options in Addiction–Medical management of alcohol and opiate abuse., C. Brewer. Gaskell/Royal College of Psychiatrists, London 1993; 19–28
  • Babow I. The treatment monopoly in alcoholism and drug dependence: a sociological critique. Journal of Drug Issues 1975; 5: 120–128
  • Bale R., VanStone W., Kuldau J., Engelsing T, Elashoff R., Zarcone V. Therapeutic communities vs methadone maintenance. A prospective controlled study of narcotic addiction treatment: design and one-year follow-up. Archives of General Psychiatry 1980; 37: 179–93
  • Ball J., Ross A. The effectiveness of methadone maintenance treatment: patients, programs, services and outcome. Springer Verlag, New York 1991
  • Bammer G., Gerrard G. (1992) Heroin treatment–new alternatives. Proceedings of a One-day seminar. 1992. Becker House, Canberra
  • Battersby M., Farrell M., Gossop M., Robson P., Strang J. ‘Horse-trading’: prescribing injectable opiates to opiate addicts. A descriptive study. Drug and Alcohol Review 1992; 11: 35–412
  • Bell J., Bowron P., Lewis I., Batey J. Serum levels of methadone in maintenance clients who persist in illicit drug use. British Journal of Addiction 1990; 85: 1599–1602
  • Berridge V., Edwards G. Opium and the people. Yale University Press, New Haven 1987
  • Brahen L., Henderson R., Capone T., et al. Naltrexone treatment in ajail work release program. Journal of Clinical Psychiatry 1984; 45: 49–52
  • Brewer C., Perrett L. Brain damage due to alcohol consumption: an air-encephalographic, psychometric and EEG study. British Journal of Addiction 1971; 66: 170–82
  • Brewer C., Lait J. Some facts of therapeutic life. Can Social Work Survivel. Temple Smith, London 1980
  • Brewer C. How effective is the standard dose of disulfiram? A review of the disulfiram-alcohol reaction in practice. British Journal of Psychiatry 1984; 144: 200–202
  • Brewer C, Rezae H., Bailey C. Opioid withdrawal and naltrexone induction in 48–72 hours using a modification of the naltrexone-clonidine technique. British Journal of Psychiatry 1988a; 153: 340–3
  • Brewer C. Doctors heal the parts ordinary health-professionals cannot reach. Journal of the Royal Society of Health 1988b; 108(1)15–19
  • Brewer C. Combining pharmacological antagonists and behavioural psychotherapy in treating addictions: why it is effective but unpopular. British Journal of Psychiatry 1990; 157: 34–40
  • Brewer C. Intravenous Methadone Maintenance: A British Response to Persistent Opiate Injectors. Drug Addiction and AIDS, N. Loimer, R. Springer, A. Schmid. Springer Verlag, New York 1991; 187–199
  • Brewer C. Invited Review: Recent Developments in Disulfiram Treatment. Alcohol & Alcoholism 1993a; 28(4)383–395
  • Brewer C. Long-term, high-dose disulfiram in the treatment of alcohol abuse. British Journal of Psychiatry 1993b; 163: 687–89
  • Brewer C. What the textbooks say about disulfiram: a review of recent publications. Treatment Options in Addiction–Medical management of alcohol and opiate abuse, C. Brewer. Gaskell/Royal College of Psychiatrists, London 1993c
  • Brewer C. Hair Analysis as a tool for monitoring and managing patients on methadone maintenance. A discussion. Forensic Science International 1993d; 63: 277–283
  • Brickman B. Psychoanalysis and substance abuse: toward a more effective approach. Journal of the American Academy of Psychoanalysis 1988; 16: 359–79
  • Caplehorn J., Dalton S., Guff M., Petrenas A.-M. Retention in methadone maintenance and heroin addicts' risk of death. Addiction 1994; 89: 203–7
  • Caplehorn J. Methadone maintenance treatment: Britain has been over-committed to psychological theories of drug dependence. British Medical Journal 1995; 310: 463
  • Chick J., Gough K., Wojciech F., et al. Disulfiram treatment of alcoholism. British Journal of Psychiatry 1992; 161: 84–89
  • Christensen J. K., Meller I. W., Ronsted P., et al. Dose-effect relationship of disulfiram in human volunteers. I: clinical studies. Pharmacology and Toxicology 1991; 68: 163–165
  • Davidson K. Diagnosis of depression in alcohol dependence: changes in prevalence with drinking status. British Journal of Psychiatry 1993; 166: 199–204
  • Dirks J. The efficacy of the Amsterdam morphine-dispensing programme. Drug Misuse and Dependence, H. Ghodse, C. Kaplan, R. Mann, 1990, Parthenon
  • Carnforth Dole V. Thoughts on narcotic addiction. Bulletin of the New York Academy of Medicine 1965; 41: 211–3
  • Dole V. Methadone treatment and the acquired immunodeficiency syndrome epidemic. Journal of American Medical Association 1989; 262(12)1681–2
  • Dole V. Methadone maintenance: optimising dosage by estimating plasma level. Journal of Addictive Diseases 1994; 13: 1–4
  • Durlak J. Comparative effectiveness of professional and paraprofessional helpers. Psychological Bulletin 1979; 86: 80–92
  • Edwards G., Orford J., Egert S., et al. Alcoholism: A controlled Trial of “treatment” and “advice”. Quarterly Journal of Studies of Alcohol 1977; 38(5)1004–1031
  • Farrell M., Ward J., Mattick R., Hall W., Stimson G., DesJarlais D., Gossop M., Strang J. Methadone maintenance treatment in opiate dependence: a review. British Medical Journal 1994; 309: 997–1001
  • Friedman P., DesJarlais D. C, Peyser N. P., et al. Retention of patients who entered methadone maintenance via an interim methadone clinic. Journal of Psychoactive Drugs 1994; 26: 217–21
  • Galanter M. Network therapy for addiction: a model for office practice. American Journal of Psychiatry 1993; 150: 28–36
  • Gelder M. G., Marks I., Wolff H. H. Desensitisation and psychotherapy in the treatment of phobic states: a controlled clinical enquiry. British Journal of Psychiatry 1967; 113: 53–73
  • Gerra G., Marcato A., Caccavari R., et al. Clonidine and opiate receptor antagonists in the treatment of heroin addiction. Journal of Substance Abuse Treatment 1995; 12: 35–41
  • Goldstein A., Hansteen R., Horns W. Control of methadone dosage by patients. Journal of the American Medical Association 1975; 234: 734–7
  • Gossop M., Green L., Phillips G. What happens to opiate addicts immediately after treatment: a prospective follow-up study. British Medical Journal 1987; 294: 1377–80
  • Gottheil E., Sterling R., Weinstein S. Diminished illicit drug use as a consequence of long-term methadone maintenance. Journal of Addictive Diseases 1993; 12: 45–57
  • Greenwood J. Persuading general practitioners to prescribe–good husbandry or a recipe for chaos. British Journal of Addiction 1992; 87(4)567–75
  • Gronbladh L., Gunne L. The Swedish methadone maintenance program: a controlled study. Drug and Alcohol Dependence 1981; 7: 249–56
  • Gunne L. Politicians and scientists in the combat against drug abuse. Drug and Alcohol Dependence 1990; 25: 241–244
  • Haemmig R. Harm reduction in Bern: from outreach to heroin maintenance. Bulletin of the New York Academy of Medicine 1995; 371–9
  • Harrison L. Substance misuse and social work qualifying training in the British Isles: a survey of CQSW courses. British Journal of Addiction 1992; 87: 635–42
  • Hartnoll R., Mitcheson M., Battersby A. Evaluation of heroin maintenance in a controlled trial. Arc-hives of General Psychiatry 1980; 37: 877–884
  • Havassy B., Hargreaves W. Allowing methadone clients control over dosage: a 48-week controlled trial. Addictive Behaviors 1981; 6: 283–288
  • Heather N. Disulfiram treatment for alcoholism. Does it deserve another chance. British Medical Journal 1989; 299: 471–472
  • Holmstrand J., Anggard E., Gunne L. Methadone maintenance: plasma levels and therapeutic outcome. Clinical Pharmacology and Therapeutics 1978; 21: 175–80
  • Huxley P. Social work practice in mental health. Gower, Aldershot 1985
  • Jensen E. A proper use of Antabuse: the Danish model of treatment. British Journal of Clinical Practice 1984; 38(Suppl. 36)117–122
  • Johansson B., Angelo H., Christensen J., Moller I., Ronsted P. Dose-effect relationship of disulfiram in human volunteers II: a study of the relationship between the disulfiram-alcohol reaction and plasma concentrations of acetaldehyde, diethyldithiocarbamic acid methyl ester and erythrocyte aldehyde dehydrogenase activity. Pharmacology and Toxicology 1991; 68: 166–70
  • Johnsen J., Morland J. Depot preparations of disulfiram: experimental and clinical results. Acta Psychiatrica Scandinavica 1992; 86: 27–30
  • Kaaber K., Menne T., Veien N., Baadsgaard O. Some adverse effects of disulfiram in the treatment of nickel-allergic patients. Dermatosen Beruf Umwelt 1987; 38: 209–211
  • Keso L., Salaspuro M. In-patient treatment of employed alcoholics: a randomised trial of Hazelden-type and traditional treatments. Alcoholism: Clinical and Experimental Research 1990; 14: 584–9
  • Kleber H. D., Kosten T. R. Naltrexone induction: psychologic and pharmacologic strategies. Journal of Clinical Psychiatry 1984; 45: 29–38
  • Kreek M. Rationale for maintenance pharmacotherapy of opiate dependence. Addictive States, C. O'Brien, J. Jaffe. Raven Press, New York 1992; 205–30
  • Kwentus J., Major L. Disulfiram in the treatment of alcoholism: a review. Journal of Studies on Alcohol 1979; 40: 428–39
  • Legarda J., Gossop M. A 24-h inpatient detoxification treatment for heroin addicts: a preliminary investigation. Drug and Alcohol Dependence 1994; 35: 91–93
  • Liappas I., et al. Thoughts on the Sheffield non-prescription programme for narcotic users. British Journal of Addiction 1987; 82: 999–1006
  • Loimer N., Schmid R., Lenz K., Presslich O., Grunberger J. Acute blocking of naloxone-precipi-tated opiate withdrawal symptoms by methohexitone. British Journal of Psychiatry 1990; 157: 748–752
  • Loimer N., Schmid R. The use of plasma levels to optimise methadone maintenance treatment. Drug and Alcohol Dependence 1992; 30: 241–246
  • Loimer N., Lenz K., Schmid R., Presslich O. Technique for greatly shortening the transition from methadone to naltrexone maintenance of patients addicted to opiates. American Journal of Psvchiatry 1991a; 148: 933–935
  • Loimer N., Linzmayer L., Grunberger J. Comparison between observer assessment and self rating of withdrawal distress during opiate detoxification. Drug and Alcohol Dependence 1991b; 28(3)265–268
  • MacDonald G., Sheldon B., Gillespie J. Contemporary studies of the effectiveness of social work. British Journal of Social Work 1992; 22: 615–643
  • Maddux J., Esquivel M., Vogtsberger K., Desmond D. Methadone dose and urine morphine. Journal of Substance Abuse and Treatment 1991; 8: 195–201
  • Mathew R. J., Georgi J., Nagy P. Substance abuse treatment: beyond the Minnesota Model. North Carolina Medical Journal 1994; 55: 224–6
  • Meyers R. The community reinforcement approach: a systematic cognitive-behaviour therapy for addictive behaviours. Paper presented at 7th International conference on the treatment of addictive behaviours. May, 281995. The Netherlands, Leeuwenhorst
  • Miller W. The effectiveness of treatment for substance abuse: reasons for optimism. Journal of Substance Abuse Treatment 1992; 9: 93–102
  • Miller W., Hester R. The effectiveness of alcoholism treatment: what research reveals. The addictive behaviours: processes of change, W. Miller, N. Heather. Plenum Books, New York 1986a
  • Miller W., Hester R. In-patient alcoholism treatments: who benefits. American Psychologist 1986b; 41: 794–805
  • Najavits L., Weiss R. Variations in therapist effectiveness in the treatment of patients with substance use disorders: an empirical review. Addiction 1994; 89: 679–88
  • Newman R., Whitehill W. Double-blind comparison of methadone and placebo maintenance treatments of narcotic addicts in Hong Kong. Lancet 1979; 2: 485–88
  • Ojehagen A., Berglund M. To keep the alcoholic in out-patient treatment. A differentiated approach through treatment contracts. Acta Psychiatrica Scandinavica 1986; 73(1)68–75
  • O'Malley S. S., Jaffe A. J., Chang G., et al. Naltrexone and coping skills therapy for alcohol dependence: a controlled study. Archives of General Psychiatry 1992; 49: 881–7
  • Phillips M. Disulfiram-induced fulminating hepatitis and monitoring guidelines. Journal of Clinical Psychiatry 1990; 51: 168
  • Phillips M., Greenberg J. Dose-ranging study of depot disulfiram in alcohol abusers. Alcoholism: Clinical & Experimental Research 1992; 16: 964–967
  • Pini L., Ferretti C, Trenti T., et al. Effects of long term treatment with naltrexone on hepatic enzyme activity. Drug Metabolism and Drug Interactions 1991; 9: 161–174
  • Poulsen E. H., Loft S., Andersen J. R., Andersen M. Disulfiram therapy–adverse drug reactions and interactions. Acta Psychiatrica Scandinavica 1992; 86: 59–66
  • Price J. Abstinence and Antabuse: symbolism and supervision. Medical Journal of Australia 1994; 160: 175
  • Prioleau L., Murdock M., Brody N. An analysis of psychotherapy versus placebo studies. The Behavioral and Brain Sciences 1983; 6: 275–310
  • Ron M. A. Brain damage in chronic alcoholism: a neuropathogical, neuroradiological and psychological review. Psychological Medicine 1977; 7: 103–11
  • Salmela K., Keso L., Salaspuro M. The community reinforcement approach: a systematic cognitive-behaviour therapy for addictive behaviours. Paper presented at ICTAB VI, Santa Fe, January, 1993
  • Saunders B. Treatment does not work: some criteria of failure. The Misuse of Alcohol: Crucial Issues in Dependence, Treatment & Prevention, N. Heather, I. Robertson, P. Davies. Croom Helm, London 1985; 112–116
  • Sereny G., Sharma V., Holt J., Gordis E. Mandatory supervised Antabuse therapy in an out-patient alcoholism program: a pilot study. Alcoholism: Clinical & Experimental Research 1986; 10: 290–92
  • Sheldon B. Theory and practice in social work: a re-examination of a tenuous relationship. British Journal of Social Work 1978; 8: 1–22
  • Schuckit M. A. Alcohol and depression: a clinical perspective. Acta Psychiatrica Scandinavica, Suppl. 1994; 377: 28–32
  • Shufman E. N., Porat S., Witztum E., Bar-Hamburger R., Gandacu D. The efficacy of naltrexone in preventing reabuse of heroin after detoxification. Biological Psychiatry 1994; 35: 935–45
  • Sloane R., Staples F, Cristol A., Yorkston N., Whipple K. Psychotherapy versus Behaviour Therapy. Harvard University Press, Cambridge, Mass 1975
  • Strain E. C, Stitzer M. L., Liebson I., Bigelow G. E. Dose-Response Effects of Methadone in the Treatment of Opioid Dependence. Annals of internal Medicine 1993a; 119: 23–27
  • Strain E. C, Stitzer M., Liebson I., Bigelow G. Methadone dose and treatment outcome. Drug and Alcohol Dependence 1993b; 33: 105–17
  • Strang J., Farrell M. Alcohol and drugs. British Medical Journal 1992; 304: 489
  • Strang J., Ruben S., Farrell M., Gossop M. Prescribing heroin and other injectable drugs. Heroin Addiction and Drug Policy: the British system, J. Strang, M. Gossop. Oxford University Press, Oxford 1994
  • Strupp H., Hadley S. Specific versus non-specific factors in psychotherapy: a controlled study of outcome. Archives of General Psychiatry 1979; 36: 1125–36
  • Tilly J., Cornish J., Metzger D. S., Woody G. E., McLellan A. T., O'Brien C. P. Naltrexone and the treatment of federal probationers. NIDA Research Monograph 1991; 119: 458
  • Vailliant G. Natural history of male alcoholism, V: is alcoholism the cart or the horse to sociopathy. British Journal of Addiction 1983; 78: 317–26
  • Vanichseni S., Wongsuwan B. A controlled trial of methadone maintenance in a population of intravenous drug users in Bangkok: implications for prevention of HIV. International Journal of Addictions 1991; 26: 1313–20
  • Washton A. M., Pottash A. C., Gold M. S. Naltrexone in addicted business executives and physicians. Journal of Clinical Psychiatry 1984; 45(9)511–5
  • Weinstein S. P., Gottheil E., Sterling R. C., DeMaria P. A. Long-Term Methadone Maintenance Treatment: Some Clinical Examples. Journal of Substance Abuse Treatment 1993; 10: 277–281
  • Wright C, Vafir J. A., Lake C. Disulfiram-induced fulminating hepatitis: guidelines for liver-panel monitoring. Journal of Clinical Psychiatry 1988; 49: 430–34
  • Yancovitz S., DesJarlais D., Peyser N., Drew E., Friedman P., Trigg H. A randomised trial of an interim methadone maintenance clinic. American Journal of Public Health 1991; 81: 1185–91

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