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Research Articles

Size and surface charge of gold nanoparticles determine absorption across intestinal barriers and accumulation in secondary target organs after oral administration

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Pages 36-46 | Received 27 Sep 2010, Accepted 04 Jan 2011, Published online: 10 Feb 2011

References

  • Aggarwal P, Hall JB, McLeland CB, Dobrovolskaia MA, McNeil SE. 2009. Nanoparticle interaction with plasma proteins as it relates to particle biodistribution, biocompatibility and therapeutic efficacy. Adv Drug Deliv Rev 61(6):428–437.
  • Asuri P, Karajanagi SS, Yang H, Yim TJ, Kane RS, Dordick JS. 2006. Increasing protein stability through control of the nanoscale environment. Langmuir 22(13):5833–5836.
  • Balasubramanian R, Guo R, Mills AJ, Murray RW. 2005. Reaction of Au(55)(PPh(3))(12)Cl(6) with thiols yields thiolate monolayer protected Au(75) clusters. J Am Chem Soc 127(22):8126–8132.
  • Bhardwaj V, Ankola DD, Gupta SC, Schneider M, Lehr CM, Kumar MN. 2009. PLGA nanoparticles stabilized with cationic surfactant: Safety studies and application in oral delivery of paclitaxel to treat chemical-induced breast cancer in rat. Pharm Res 26(11):2495–2503.
  • Cartiera MS, Johnson KM, Rajendran V, Caplan MJ, Saltzman WM. 2009. The uptake and intracellular fate of PLGA nanoparticles in epithelial cells. Biomaterials 30(14):2790–2798.
  • Cho M, Cho WS, Choi M, Kim SJ, Han BS, Kim SH, Kim HO, Sheen YY, Jeong J. 2009. The impact of size on tissue distribution and elimination by single intravenous injection of silica nanoparticles. Toxicol Lett 189(3):177–183.
  • Connor EE, Mwamuka J, Gole A, Murphy CJ, Wyatt MD. 2005. Gold nanoparticles are taken up by human cells but do not cause acute cytotoxicity. Small 1(3):325–327.
  • des Rieux A, Fievez V, Garinot M, Schneider YJ, Preat V. 2006. Nanoparticles as potential oral delivery systems of proteins and vaccines: A mechanistic approach. J Control Release 116(1):1–27.
  • des Rieux A, Ragnarsson EG, Gullberg E, Preat V, Schneider YJ, Artursson P. 2005. Transport of nanoparticles across an in vitro model of the human intestinal follicle associated epithelium. Eur J Pharm Sci 25(4–5):455–465.
  • Dobrovolskaia MA, Patri AK, Zheng J, Clogston JD, Ayub N, Aggarwal P, Neun BW, Hall JB, McNeil SE. 2009. Interaction of colloidal gold nanoparticles with human blood: Effects on particle size and analysis of plasma protein binding profiles. Nanomedicine 5(2):106–117.
  • Doyle-McCullough M, Smyth SH, Moyes SM, Carr KE. 2007. Factors influencing intestinal microparticle uptake in vivo. Int J Pharm 335(1–2):79–89.
  • Florence AT, Hillery AM, Hussain N, Jani PU. 1995. Factors affecting the oral uptake and translocation of polystyrene nanoparticles: Histological and analytical evidence. J Drug Target 3(1):65–70.
  • Florence AT. 2007. Pharmaceutical nanotechnology: More than size. Ten topics for research. Int J Pharm 339(1–2):1–2.
  • Florence AT, Sakthivel T, Toth I. 2000. Oral uptake and translocation of a polylysine dendrimer with a lipid surface. J Control Release 65(1–2):253–259.
  • Gebert A, Rothkotter HJ, Pabst R. 1996. M cells in Peyer's patches of the intestine. Int Rev Cytol 167:91–159.
  • Geiser M, Rothen-Rutishauser B, Kapp N, Schurch S, Kreyling W, Schulz H, Semmler M, Im HV, Heyder J, Gehr P. 2005. Ultrafine particles cross cellular membranes by nonphagocytic mechanisms in lungs and in cultured cells. Environ Health Perspect 113(11):1555–1560.
  • Hariharan S, Bhardwaj V, Bala I, Sitterberg J, Bakowsky U, Ravi Kumar MN. 2006. Design of estradiol loaded PLGA nanoparticulate formulations: A potential oral delivery system for hormone therapy. Pharm Res 23(1):184–195.
  • He C, Hu Y, Yin L, Tang C, Yin C. 2010. Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles. Biomaterials 31(13):3657–3666.
  • Hillery AM, Jani PU, Florence AT. 1994. Comparative, quantitative study of lymphoid and non-lymphoid uptake of 60 nm polystyrene particles. J Drug Target 2(2):151–156.
  • Hillyer JF, Albrecht RM. 2001. Gastrointestinal persorption and tissue distribution of differently sized colloidal gold nanoparticles. J Pharm Sci 90(12):1927–1936.
  • Hirn S, Semmler-Behnke M, Schleh C, Wenk A, Lipka J, Schäffler M, Takenaka S, Möller W, Schmid G, Simon U, Kreyling WG. Particle size-dependent and surface charge-dependent biodistribution of gold nanoparticles after intravenous administration. Eur J Pharm Biopharm. 2010 Dec 31. [Epub ahead of print]
  • Hussain N, Florence AT. 1998. Utilizing bacterial mechanisms of epithelial cell entry: Invasin-induced oral uptake of latex nanoparticles. Pharm Res 15(1):153–156.
  • Jani P, Halbert GW, Langridge J, Florence AT. 1990. Nanoparticle uptake by the rat gastrointestinal mucosa: Quantitation and particle size dependency. J Pharm Pharmacol 42(12):821–826.
  • Jani P, Halbert GW, Langridge J, Florence AT. 1989. The uptake and translocation of latex nanospheres and microspheres after oral administration to rats. J Pharm Pharmacol 41(12):809–812.
  • Jani PU, Nomura T, Yamashita F, Takakura Y, Florence AT, Hashida M. 1996. Biliary excretion of polystyrene microspheres with covalently linked FITC fluorescence after oral and parenteral administration to male Wistar rats. J Drug Target 4(2):87–93.
  • Kuo CT, Yu JY, Huang MJ, Chen CH. 2010. On the size evolution of gold-monolayer-protected clusters by ligand place-exchange reactions: the effect of headgroup-gold interactions. Langmuir 26(9):6149–6153.
  • Lacerda SH, Park JJ, Meuse C, Pristinski D, Becker ML, Karim A, Douglas JF. 2010. Interaction of gold nanoparticles with common human blood proteins. ACS Nano 4(1):365–379.
  • Lundqvist M, Stigler J, Elia G, Lynch I, Cedervall T, Dawson KA. 2008. Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts. Proc Natl Acad Sci USA 105(38):14265–14270.
  • Lundqvist M, Sethson I, Jonsson BH. 2004. Protein adsorption onto silica nanoparticles: Conformational changes depend on the particles' curvature and the protein stability. Langmuir 20(24):10639–10647.
  • Nassimi M, Schleh C, Lauenstein HD, Hussein R, Hoymann HG, Koch W, Pohlmann G, Krug N, Sewald K, Rittinghausen S, Braun A, Muller-Goymann C. 2010. A toxicological evaluation of inhaled solid lipid nanoparticles used as a potential drug delivery system for the lung. Eur J Pharm Biopharm 75(2):107–116.
  • Nassimi M, Schleh C, Lauenstein HD, Hussein R, Lubbers K, Pohlmann G, Switalla S, Sewald K, Muller M, Krug N, Muller-Goymann CC, Braun A. 2009. Low cytotoxicity of solid lipid nanoparticles in in vitro and ex vivo lung models. Inhal Toxicol 21(S1):104–109.
  • Oeff K, Konig A. 1955. Das Blutvolumen einiger Rattenorgane und ihre Restblutmenge nach entbluten bzw. durchspülung - Bestimmung mit P-32-markierten Erythrocyten. Naunyn-Schmiedebergs Archiv Fur Experimentelle Pathologie Und Pharmakologi 226(1):98–102.
  • Pan Y, Leifert A, Ruau D, Neuss S, Bornemann J, Schmid G, Brandau W, Simon U, Jahnen-Dechent W. 2009. Gold nanoparticles of diameter 1.4 nm trigger necrosis by oxidative stress and mitochondrial damage. Small 5(18):2067–2076.
  • Pan Y, Neuss S, Leifert A, Fischler M, Wen F, Simon U, Schmid G, Brandau W, Jahnen-Dechent W. 2007. Size-dependent cytotoxicity of gold nanoparticles. Small 3(11):1941–1949.
  • Potten CS, Loeffler M. 1990. Stem cells: Attributes, cycles, spirals, pitfalls and uncertainties. Lessons for and from the crypt. Development 110(4):1001–1020.
  • Powell JJ, Faria N, Thomas-McKay E, Pele LC. 2010. Origin and fate of dietary nanoparticles and microparticles in the gastrointestinal tract. J Autoimmun 34(3):J226–233.
  • Rimoldi M, Rescigno M. 2005. Uptake and presentation of orally administered antigens. Vaccine 23(15):1793–1796.
  • Ruenraroengsak P, Cook JM, Florence AT. 2010. Nanosystem drug targeting: Facing up to complex realities. J Control Release 141(3):265–276.
  • Samstein RM, Perica K, Balderrama F, Look M, Fahmy TM. 2008. The use of deoxycholic acid to enhance the oral bioavailability of biodegradable nanoparticles. Biomaterials 29(6):703–708.
  • Sass W, Dreyer HP, Seifert J. 1990. Rapid insorption of small particles in the gut. Am J Gastroenterol 85(3):255–260.
  • Schmid G. 2008. The relevance of shape and size of Au55 clusters. Chem Soc Rev 37(9):1909–1930.
  • Seifert J, Sass W. 1990. Intestinal absorption of macromolecules and small particles. Dig Dis 8(3):169–178.
  • Seifert J, Haraszti B, Sass W. 1996. The influence of age and particle number on absorption of polystyrene particles from the rat gut. J Anat 189(Pt 3):483–486.
  • Semmler-Behnke M, Kreyling WG, Lipka J, Fertsch S, Wenk A, Takenaka S, Schmid G, Brandau W. 2008. Biodistribution of 1.4- and 18-nm gold particles in rats. Small 4(12):2108–2111.
  • Shang W, Nuffer JH, Muniz-Papandrea VA, Colon W, Siegel RW, Dordick JS. 2009. Cytochrome C on silica nanoparticles: Influence of nanoparticle size on protein structure, stability, and activity. Small 5(4):470–476.
  • Smyth SH, Feldhaus S, Schumacher U, Carr KE. 2008. Uptake of inert microparticles in normal and immune deficient mice. Int J Pharm 346(1–2):109–118.
  • Sonavane G, Tomoda K, Sano A, Ohshima H, Terada H, Makino K. 2008. In vitro permeation of gold nanoparticles through rat skin and rat intestine: Effect of particle size. Colloids Surf B Biointerfaces 65(1):1–10.
  • Sperling RA, Rivera Gil P, Zhang F, Zanella M, Parak WJ. 2008. Biological applications of gold nanoparticles. Chem Soc Rev 37(9):1896–1908.
  • Tominaga T, Tenma S, Watanabe H, Giebel U, Schmid G. 1996. Tracer diffusion of a ligand-stabilized two-shell gold cluster. Chem Lett (12):1033–1034.
  • Torjman MC, Joseph JI, Munsick C, Morishita M, Grunwald Z. 2005. Effects of isoflurane on gastrointestinal motility after brief exposure in rats. Int J Pharm 294(1–2):65–71.
  • Vertegel AA, Siegel RW, Dordick JS. 2004. Silica nanoparticle size influences the structure and enzymatic activity of adsorbed lysozyme. Langmuir 20(16):6800–6807.
  • Walczyk D, Bombelli FB, Monopoli MP, Lynch I, Dawson KA. 2010. What the cell ‘sees’ in bionanoscience. J Am Chem Soc 132(16):5761–5768.