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Research Article

Surface charge-specific cytotoxicity and cellular uptake of tri-block copolymer nanoparticles

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Pages 71-84 | Received 14 Mar 2011, Accepted 12 Oct 2011, Published online: 17 Nov 2011

References

  • Alberts AJB, Lewis J, Raff M, Roberts K, Walter P. 2002. Molecular Biology of the Cell. Garland Science, Taylor and Francis group. New York.
  • Asati A, Santra S, Kaittanis C, Perez JM. 2010. Surface-charge-dependant cell localization and cytotoxicity of cerium oxide nanoparticles. ACS Nano 4:5321–5331.
  • Bhattacharjee S, de Haan LHJ, Evers NM, Jiang X, Marcelis ATM, Zuilhof H, 2010. Role of surface charge and oxidative stress in cytotoxicity of organic monolayer-coated silicon nanoparticles towards macrophage NR8383 cells. Part Fibre Toxicol 7:25.
  • Brand W, Schutte MW, Williamson G, van Zanden JJ, Cnubben NHP, Groten JP, 2006. Flavonoid-mediated inhibition of intestinal ABC transporters may affect the oral bioavailability of drugs, food-borne toxic compounds and bioactive ingredients. Biomed Pharmacother 60:508–519.
  • Brown DM, Donaldson K, Borm PJ, Schins RP, Dehnhardt M, Gilmour P, 2004. Calcium and ROS-mediated activation of transcription factors and TNF-alpha cytokine gene expression in macrophages exposed to ultrafine particles. Am J Physiol Lung Cel Mol Physiol 286:L344–L353.
  • Cho EC, Xie JW, Wurm PA, Xia YN. 2009. Understanding the role of surface charge in cellular adsorption versus internalization by selectively removing gold nanoparticles on the cell surface with I2/KI etchant. Nano Lett 9:1080–1084.
  • Clift MJ, Bhattacharjee S, Brown DM, Stone V. 2010. The effects of serum on the toxicity of manufactured nanoparticles. Toxicol Lett 198:358–365.
  • Dif A, Henry E, Artzner F, Baudy-Floc'h M, Schmutz M, Dahan M, 2008. Interaction between water-soluble peptidic CdSe/ZnS nanocrystals and membranes: formation of hybrid vesicles and condensed lamellar phases. J Am Chem Soc 130:8289–8296.
  • Donaldson K, Aitken R, Tran L, Stone V, Duffin R, Forrest G, 2006. Carbon nanotubes: a review of their properties in relation to pulmonary toxicology and workplace safety. Toxicol Sci 92:5–22.
  • Foster KA, Yazdanian M, Audus KL. 2001. Microparticulate uptake mechanisms of in-vitro cell culture models of the respiratory epithelium. J Pharm Pharmacol 53:57–66.
  • Foucaud L, Wilson MR, Brown DM, Stone V. 2007. Measurement of reactive species production by nanoparticles prepared in biologically relevant media. Toxicol Lett 174:1–9.
  • Gentili PL, Mugnaia M, Bussotti L, Righini R, Foggi P, Cicchi S, 2007. The ultrafast energy transfer process in naphtole-nitrobenzofuran bichromophoric molecular systems. A study by femtosecond UV-vis pump-probe spectroscopy. J Photochem Photobiol A187:209–221.
  • Green M, Howan E. 2005. Semiconductor quantum dots and free radical induced DNA nicking. Chem Commun 1:121–123.
  • Goodwin LG, Richards WHG, Udall V. 1957. The toxicity of diaminodiphenoxyalkanes. Br J Pharmacol 12:468–474.
  • Harush-Frenkel O, Debotton N, Benita S, Altschuler Y. 2007. Targeting of nanoparticles to the clathrin-mediated endocytic pathway. Biochem Biophys Res Commun 353:26–32.
  • Hauck TS, Ghazani AA, Chan WC. 2008. Assessing the effect of surface chemistry on gold nanorod uptake, toxicity and gene expression in mammalian cells. Small 4:153–159.
  • Hong SP, Bielinska AU, Mecke A, Keszler B, Beals JL, Shi XY, 2004. Interaction of poly(amidoamine) dendrimers with supported lipid bilayers and cells: hole formation and the relation to transport. Bioconjugate Chem 15:774–782.
  • Hong SP, Leroueil PR, Janus EK, Peters J, Kober MM, Islam MT, 2006. Interaction of polycationic polymers with supported lipid bilayers and cells: nanoscale hole formation and enhanced membrane permeability. Bioconjugate Chem 17:728–734.
  • Huang M, Ma Z, Khor E, Lim LY. 2002. Uptake of FITC-chitosan nanoparticles by A549 cells. Pharm Res 19:1488–1494.
  • Huang WM, Han XJ, Wang EK. 2003. Defect formation induced by PAMAM dendrimers on Pt-supported bilayer lipid membranes investigated by electrochemistry. J Electrochem Soc 150:E218–E221.
  • Huth S, Lausier J, Gersting SW, Rudolph C, Plank C, Welsch U, 2004. Insights into the mechanism of magnetofection using PEI-based magnetofectins for gene transfer. J Med Genet 6:923–936.
  • Karatas OF, Sezgin E, Aydin O, Culha M. 2009. Interaction of gold nanoparticles with mitochondria. Colloids Surf B 71:315–318.
  • Kemp SJ, Thorley AJ, Gorelik J, Seckl MJ, O´Hare MJ, Arcaro A, 2008. Immortalization of human alveolar epithelial cells to investigate nanoparticle uptake. Am J Respir Cell Mol Biol 39:591–597.
  • Khoee S, Hassanzadeh S, Goliaie B. 2007. Effects of hydrophobic drug-polyesteric core interactions on drug loading and release properties of poly(ethylene glycol)-polyester-poly(ethylene glycol) tri-block core-shell nanoparticles. Nanotechnology 18:17.
  • Kim C, Agasti SS, Zhu Z, Isaacs L, Rotello V. 2010. Recognition-mediated activation of therapeutic gold nanoparticles inside living cells. Nat Chem 2:962–965.
  • Krug HF, Wick P. 2011. Nanotoxicology: an interdisciplinary challenge. Angew Chem 50:1260–1278.
  • Kwon S, Kim H, Ha J, Lee S. 2011. Prevention of protein and polymeric nanoparticles adsorption using perfluoropolyether. J Ind Eng Chem 17:259–263.
  • Leroueil PR, Hong SY, Mecke A, Baker JR, Orr BG, Holl MMB. 2007. Nanoparticle interaction with biological membranes: does nanotechnology present a janus face? Acc Chem Res 40:335–342.
  • Li N, Sioutas C, Cho A, Schmitz D, Misra C, Sempf J, 2003. Ultrafine particulate pollutants induce oxidative stress and mitochondrial damage. Environ Health Perspect 111:455–460.
  • Lin W, Huang YW, Zhou XD, Ma Y. 2006. Toxicity of cerium oxide nanoparticles in human lung cancer cells. Int J Toxicol 25:451–457.
  • Lin J, Zhang H, Chen Z, Zhng Y. 2010. Penetration of lipid membranes by gold nanoparticles: insights into cellular uptake, cytotoxicity and their relationship. ACS Nano 4:5421–5429.
  • Loccufier J, Bos MV, Schacht E. 1991. Convenient method for the analysis of primary and secondary hydroxyl end groups in polyethers. Polym Bull 27:201–204.
  • Ma Z, Lim LY. 2003. Uptake of chitosan and associated insulin on Caco-2 cell monolayers: a comparison between chitosan molecules and chitosan nanoparticles. Pharm Res 20:1812–1819.
  • Martin AL, Bernas LM, Rutt BK, Foster PJ, Gillies ER. 2008. Enhanced cell uptake of superparamagnetic nanoparticles functionaluized by dendritic guanidines. Bioconjug Chem 19:2375–2384.
  • Mayer A, Vadon M, Rinner B, Novak A, Wintersteiger R, Frohlich E. 2009. The role of nanoparticle size in hemocompatibility. Toxicology 258:139–147.
  • Mecke A, Lee DK, Ramamoorthy A, Orr BG, Holl MMB. 2005. Synthetic and natural polycationic polymer nanoparticles interact selectively with fluid-phase domains of DMPC lipid bilayers. Langmuir 21:8588–8590.
  • Nemmar A, Hoylaerts MF, Hoet PH, Vermylen J, Nemery B. 2003. Size effect of intracellularly instilled particles on pulmonary inflammation and vascular thrombosis. Toxicol Appl Pharmacol 186:38–45.
  • Orr G, Panther DJ, Phillips JL, Tarasevich BJ, Dohnalkova A, Hu D, 2007. Submicrometer and nanoscale inorganic particles exploit the actin machinery to be propelled along the microvilli-like structures into alveolar cells. ACS Nano 1:463–475.
  • Osaka T, Nakanishi T, Shanmugam S, Takahama S, Zhang H. 2009. Effect of surface charge of magnetite nanoparticles on their internalization into breast cancer and umbilical vein endothelial cells. Colloids Surf B 71:325–330.
  • Pan Y, Leifert A, Ruau D, Neuss S, Bornemann J, Schmid G Brandau W, 2009. Gold nanoparticles of diameter 1.4 nm trigger necrosis by oxidative stress and mitochondrial damage. Small 5:2067–2076.
  • Panyam J, Labhasetwar V. 2003. Dynamics of endocytosis and exocytosis of poly(D, L-lactide-co-glycolide) nanoparticles in vascular smooth muscle cells. Pharm Res 20:212–220.
  • Parimi S, Barnes TJ, Prestidge CA. 2008. PAMAM dendrimer interactions with supported lipid bilayers: a kinetic and mechanistic investigation. Langmuir 24:13532–13539.
  • Rosso-Vasic M, Sprujit E, Popovic Z, Overgaag K, van Lagen B, Grandidier B, 2009. Amine-terminated silicon nanoparticles: synthesis, optical properties and their use in bioimaging. J Mater Chem 19:5926–5933.
  • Ruizendaal L, Bhattacharjee S, Pournazari K, Rosso-Vasic M de Haan LHJ, Alink GM, Marcelis ATM, 2009. Synthesis and cytotoxicity of nanoparticles with covalently attached organic monolayers. Nanotoxicology 3:339–347.
  • Saxena RK, Williams W, McGee JK, Daniels MJ, Boykin E, Gilmour MI. 2007. Enhanced in vitro and in vivo toxicity of poly-dispersed acid functionalized single-wall carbon nanotubes. Nanotoxicology 1:291–300.
  • Sayes CM, Gobin AM, Ausman KD, Mendez J, West JL, Colvin VL. 2005. Nano-C60 cytotoxicity is due to lipid peroxidation. Biomaterials 26:7587–7595.
  • Schatzlein AG, Zinselmeyer BH, Elouzi A, Dufes C, Chim YTA, Roberts CJ, 2005. Preferential liver gene expression with polypropylenimine dendrimers. J Control Release 101:247–258.
  • Shi X, Thomas TP, Myc LA, Kotlyar A, Baker JR. 2007. Synthesis, characterization and intracellular uptake carboxyl-terminated poly(amidoamine) dendrimer-stabilized iron oxide nanoparticles. Phys Chem Chem Phys 42:5712–5720.
  • Stone V, Donaldson K. 2006. Nanotoxicology: signs of stress. Nat Nanotechnol 1:23–24.
  • Suh H, Jeong B, Rathi R, Kim SW. 1998. Regulation of smooth muscle cell proliferation using paclitaxel-loaded poly(ethylene oxide)-poly(lactide/glycolide) nanospheres. J Biomed Mater Res 42:331–338.
  • Thubagere A, Reinhard BM. 2010. Nanoparticle-induced apoptosis propagates through hydrogen-peroxide mediated bystander killing: insights from a human intestinal epithelium in vitro model. ACS Nano 4:3611–3622.
  • Vasir JK, Labhasetwar V. 2008. Quantification of the force of nanoparticle-cell membrane interactions and its influence on intracellular trafficking of nanoparticles. Biomaterials 29:4244–4252.
  • Verma A, Uzun O, Hu Y, Hu Y, Han H, Watson N, 2008. Surface-structure-regulated cell-embrane penetration by monolayer-protected nanoparticles. Nat Mater 7:588–595.
  • Verma A, Stellacci F. 2010. Effect of surface properties on nanoparticle-cell interactions. Small 6:12–21.
  • Villanueva A, Canete M, Roca AG, Calero M, Veintemillas-verdaguer S, Serna CJ, 2009. The influence of surface functionalization on the enhanced internalization of the magnetic nanoparticles in cancer cells. Nanotechnology 20:115103.
  • Vrecl M, Anderson L, Hanyaloglu A, McGregor AM, Groarke AD, Milligan G, 1998. Agonist-induced endocytosis and recycling of the gonadotropin-releasing hormone receptor: effect of β-arrestin on internalization kinetics. Mol Endocrin 12:1818–1829.
  • Wang B, Zhang L, Bae SC, Granick S. 2008. Nanoparticle-induced surface reconstruction of phospholipid membranes. Proc Natl Acad Sci 105:18171–18175.
  • Wilson MR, Lightbody JH, Donaldson K, Sales J, Duffin R, Stone V. 2002. Interactions between ultrafine particles and transition metals in vivo and in vitro. Toxicol Appl Pharmacol 184:172–179.
  • Xia T, Kovochich M, Brant J, Hotze M, Sempf J, Oberley T, 2006. Comparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigm. Nano Lett 6:1794–1807.
  • Xia T, Kovochich M, Liong M, Zink JI, Nel AE. 2008. Cationic polystyrene nanosphere toxicity depends on cell-specific endocytic and mitochondrial injury pathways. ACS Nano 2:85–96.
  • Xiao Y, Forry SP, Gao X, Holbrook RD, Telford WG, Tona A. 2010. Dynamics and mechanism of quantum dot nanoparticle cellular uptake. J Nanobiotechnology 8:13.
  • Yan X, He Q, Wang K, Duan L, Cui Y, Li J. 2007. Transition of cationic dipeptide nanotubes into vesicles and oligonucleotide delivery. Angew Chem Int Ed 46:2431–2434.
  • Yang P, Sun X, Chiu J, Sun H, He Q. 2005. Transferrin-mediated gold nanoparticle cellular uptake. Bioconjug Chem 16:494–496.
  • Zhang L, Granick S. 2006. How to stabilize phospholipid liposomes (using nanoparticles). Nano Lett 6:694–698.

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