A comparison of six major platelet functional tests to assess the impact of carbon nanomaterials on platelet function: A practical guide

References

• Bakry R, Vallant RM, Najam-ul-Haq M, Rainer M, Szabo Z, Huck CW, et al. 2007. Medicinal applications of fullerenes. Int J Nanomedicine 2:639–649.
   PubMed Web of Science ®Google Scholar
• Barlow PG, Donaldson K, MacCallum J, Clouter A, Stone V. 2005. Serum exposed to nanoparticle carbon black displays increased potential to induce macrophage migration. Toxicol Lett 155:397–401.
   PubMed Web of Science ®Google Scholar
• Bihari P, Holzer M, Praetner M, Fent J, Lerchenberger M, Reichel CA, et al. 2010. Single-walled carbon nanotubes activate platelets and accelerate thrombus formation in the microcirculation. Toxicology 269:148–154.
   PubMed Web of Science ®Google Scholar
• Burke AR, Singh RN, Carroll DL, Owen JD, Kock ND, D'Agostino R Jr, et al. 2011. Determinants of the thrombogenic potential of multiwalled carbon nanotubes. Biomaterials 32:5970–5978.
   PubMed Web of Science ®Google Scholar
• Dobrovolskaia MA, Aggarwal P, Hall JB, McNeil SE. 2008a. Preclinical studies to understand nanoparticle interaction with the immune system and its potential effects on nanoparticle biodistribution. Mol Pharm 5:487–495.
   PubMed Web of Science ®Google Scholar
• Dobrovolskaia MA, Clogston JD, Neun BW, Hall JB, Patri AK, McNeil SE. 2008b. Method for analysis of nanoparticle hemolytic properties in vitro. Nano Lett 8:2180–2187.
   PubMed Web of Science ®Google Scholar
• Donaldson K, Brown D, Clouter A, Duffin R, MacNee W, Renwick L, et al. 2002. The pulmonary toxicology of ultrafine particles. J Aerosol Med 15:213–220.
   PubMedGoogle Scholar
• Favaloro EJ. 2009. Internal quality control and external quality assurance of platelet function tests. Semin Thromb Hemost 35:139–149.
   PubMed Web of Science ®Google Scholar
• Favaloro EJ, Lippi G, Franchini M. 2010. Contemporary platelet function testing. Clin Chem Lab Med 48:579–598.
   PubMed Web of Science ®Google Scholar
• Ferraz N, Carlsson J, Hong J, Ott MK. 2008. Influence of nanoporesize on platelet adhesion and activation. J Mater Sci Mater Med 19:3115–3121.
   PubMed Web of Science ®Google Scholar
• Geys J, Nemmar A, Verbeken E, Smolders E, Ratoi M, Hoylaerts MF, et al. 2008. Acute toxicity and prothrombotic effects of quantum dots: impact of surface charge. Environ Health Perspect 116:1607–1613.
   PubMed Web of Science ®Google Scholar
• Gouya G, Jilma B, Niel M, Eichelberger B, Wolzt M, Panzer S. 2009. Cross validation of aspirin effect in healthy individuals by Impact-R and PFA-100: a double blind randomized placebo controlled trial. Platelets 20:171–176.
   PubMed Web of Science ®Google Scholar
• Harrison P, Mumford A. 2009. Screening tests of platelet function: update on their appropriate uses for diagnostic testing. Semin Thromb Hemost 35:150–157.
   PubMed Web of Science ®Google Scholar
• Hulstein JJ, Lenting PJ, de Laat B, Derksen RH, Fijnheer R, de Groot PG. 2007. beta2-Glycoprotein I inhibits von Willebrand factor dependent platelet adhesion and aggregation. Blood 110:1483–1491.
   PubMed Web of Science ®Google Scholar
• Jiang J, Oberdörster G, Biswas P. 2009. Characterization of size, surface charge, and agglomeration state of nanoparticle dispersions for toxicological studies. J Nanopart Res 11:77–89.
   Web of Science ®Google Scholar
• Jun EA, Lim KM, Kim K, Bae ON, Noh JY, Chung KH, et al. 2011. Silver nanoparticles enhance thrombus formation through increased platelet aggregation and procoagulant activity. Nanotoxicology 5(2):157–167.
   PubMed Web of Science ®Google Scholar
• Karagkiozaki VC, Logothetidis SD, Kassavetis SN, Giannoglou GD. 2010. Nanomedicine for the reduction of the thrombogenicity of stent coatings. Int J Nanomedicine 5:239–248.
   PubMed Web of Science ®Google Scholar
• Kundu SK, Heilmann EJ, Sio R, Garcia C, Davidson RM, Ostgaard RA. 1995. Description of an in vitro platelet function analyzer–PFA-100. Semin Thromb Hemost 21(Suppl 2):106–112.
   PubMed Web of Science ®Google Scholar
• Lacerda SH, Semberova J, Holada K, Simakova O, Hudson SD, Simak J. 2010. Carbon nanotubes activate store-operated calcium entry in human blood platelets. ACS Nano 5:5808–5813.
   Web of Science ®Google Scholar
• Mayer A, Vadon M, Rinner B, Novak A, Wintersteiger R, Frohlich E. 2009. The role of nanoparticle size in hemocompatibility. Toxicology 258:139–147.
   PubMed Web of Science ®Google Scholar
• Mejia J, Tichelaar F, Saout C, Toussaint O, Masereel B, Mekhalif Z, et al. 2011. Effects of the dispersion methods in Pluronic F108 on the size and the surface composition of MWCNTs and their implications in toxicology assessment. J Nanopart Res 13:655–667.
   Web of Science ®Google Scholar
• Mengistu AM, Mayer J, Boldt J, Rohm KD. 2009. Whole-blood aggregometry: are there any limits with regard to platelet counts? Acta Anaesthesiol Scand 53:72–76.
   PubMed Web of Science ®Google Scholar
• Michelson AD, Linden MD, Furman MI, Li Y, Barnard MR, Fox ML, et al. 2007. Evidence that pre-existent variability in platelet response to ADP accounts for 'clopidogrel resistance'. J Thromb Haemost 5:75–81.
   PubMed Web of Science ®Google Scholar
• Miller G, Senjen R. 2008. Out of the laboratory and on to our plates. Nanotechnology in food & agriculture. Friends Earth 1–63.
   Google Scholar
• Moghimi SM, Hunter AC, Murray JC. 2005. Nanomedicine: current status and future prospects. FASEB J 19:311–330.
   PubMed Web of Science ®Google Scholar
• Morel-Kopp MC, Aboud M, Tan CW, Kulathilake C, Ward C. 2010. Whole blood impedance aggregometry detects heparin-induced thrombocytopenia antibodies. Thromb Res 125:e234–e239.
   PubMed Web of Science ®Google Scholar
• Nel AE, Madler L, Velegol D, Xia T, Hoek EM, Somasundaran P, et al. 2009. Understanding biophysicochemical interactions at the nano-bio interface. Nat Mater 8:543–557.
   PubMed Web of Science ®Google Scholar
• Nemmar A, Hoet PH, Vandervoort P, Dinsdale D, Nemery B, Hoylaerts MF. 2007. Enhanced peripheral thrombogenicity after lung inflammation is mediated by platelet-leukocyte activation: role of P-selectin. J Thromb Haemost 5:1217–1226.
   PubMed Web of Science ®Google Scholar
• Nie S, Xing Y, Kim GJ, Simons JW. 2007. Nanotechnology applications in cancer. Annu Rev Biomed Eng 9:257–288.
   PubMed Web of Science ®Google Scholar
• Nyman D. 1977. Collagen-induced platelet aggregation: evidence of several mechanisms for the induction of platelet release by collagen. Thromb Res 10:743–751.
   PubMed Web of Science ®Google Scholar
• Oberdorster G, Maynard A, Donaldson K, Castranova V, Fitzpatrick J, Ausman K, et al. 2005. Principles for characterizing the potential human health effects from exposure to nanomaterials: elements of a screening strategy. Part Fibre Toxicol 2. 8.
   PubMed Web of Science ®Google Scholar
• Panzer S, Jilma P. 2011. Methods for testing platelet function for transfusion medicine. Vox Sang 101:1–9.
   PubMed Web of Science ®Google Scholar
• Panzer S, Rieger M, Vormittag R, Eichelberger B, Dunkler D, Pabinger I. 2007. Platelet function to estimate the bleeding risk in autoimmune thrombocytopenia. Eur J Clin Invest 37:814–819.
   PubMed Web of Science ®Google Scholar
• Patel DN, Bailey SR. 2007. Nanotechnology in cardiovascular medicine. Catheter Cardiovasc Interv 69:643–654.
   PubMed Web of Science ®Google Scholar
• Piret JP, Detriche S, Vigneron R, Vankoningsloo S, Rolin S, Mejia Mendoza JH, et al. 2010. Dispersion of multi-walled carbon nanotubes in biocompatible dispersants. J Nanopart Res 12:75–82.
   Web of Science ®Google Scholar
• Powers KW, Brown SC, Krishna VB, Wasdo SC, Moudgil BM, Roberts SM. 2006. Research strategies for safety evaluation of nanomaterials. Part VI. Characterization of nanoscale particles for toxicological evaluation. Toxicol Sci 90:296–303.
   PubMed Web of Science ®Google Scholar
• Radomski A, Jurasz P, Alonso-Escolano D, Drews M, Morandi M, Malinski T, et al. 2005. Nanoparticle-induced platelet aggregation and vascular thrombosis. Br J Pharmacol 146:882–893.
   PubMed Web of Science ®Google Scholar
• Ryan JJ, Bateman HR, Stover A, Gomez G, Norton SK, Zhao W, et al. 2007. Fullerene nanomaterials inhibit the allergic response. J Immunol 179:665–672.
   PubMed Web of Science ®Google Scholar
• Santos-Martinez MJ, Inkielewicz-Stepniak I, Medina C, Rahme K, D'Arcy DM, Fox D, et al. 2012. The use of quartz crystal microbalance with sissipation (QCM-D) for studying nanoparticle-induced platelet aggregation. Int J Nanomedicine 7:243–255.
   PubMed Web of Science ®Google Scholar
• Semberova J, De Paoli Lacerda SH, Simakova O, Holada K, Gelderman MP, Simak J. 2009. Carbon nanotubes activate blood platelets by inducing extracellular Ca2+ influx sensitive to calcium entry inhibitors. Nano Lett 9:3312–3317.
   PubMed Web of Science ®Google Scholar
• Semberova J, Holada K, Simakova O, Gelderman-Fuhrmann MP, Simak J. 2008. Carbon nanotubes activate platelets by facilitating extracellular Ca(2+) influx. Blood 112:365–366.
   Web of Science ®Google Scholar
• Shrivastava S, Bera T, Singh SK, Singh G, Ramachandrarao P, Dash D. 2009. Characterization of antiplatelet properties of silver nanoparticles. ACS Nano 3:1357–1364.
   PubMed Web of Science ®Google Scholar
• Simak J. 2009. Nanotoxicity in blood: effects of engineered nanomaterails on platelets. In: Sahu SC, Cascaciano DA, editors. Nanotoxicity: From in vivo and in vitro models to health risks. John Wiley & Sons. Chichester: pp. 191–225.
   Google Scholar
• Singh SK, Singh MK, Nayak MK, Kumari S, Shrivastava S, Gracio JJA, et al. 2011. Thrombus inducing property of atomically thin graphene oxide sheets. ACS Nano 5(6):4987–4996.
   PubMed Web of Science ®Google Scholar
• Singh SK, Singh MK, Kulkarni PP, Sonkar VK, Gracio JJA, Dash D. 2012. Amine-modified graphene: Thrombo-protective safer alternative to graphene oxide for biomedical applications. ACS Nano 6(3):2731–2740.
   PubMed Web of Science ®Google Scholar
• Sitharaman B, Shi X, Walboomers XF, Liao H, Cuijpers V, Wilson LJ, et al. 2008. In vivo biocompatibility of ultra-short single-walled carbon nanotube/biodegradable polymer nanocomposites for bone tissue engineering. Bone 43:362–370.
   PubMed Web of Science ®Google Scholar
• Smyth SS, McEver RP, Weyrich AS, Morrell CN, Hoffman MR, Arepally GM, et al. 2009. Platelet functions beyond hemostasis. J Thromb Haemost 7:1759–1766.
   PubMed Web of Science ®Google Scholar
• Stevens KN, Knetsch ML, Sen A, Sambhy V, Koole LH. 2009. Disruption and activation of blood platelets in contact with an antimicrobial composite coating consisting of a pyridinium polymer and AgBr nanoparticles. ACS Appl Mater Interfaces 1:2049–2054.
   PubMed Web of Science ®Google Scholar
• Tirosh-Wagner T, Strauss T, Rubinshtein M, Tamarin I, Mishaly D, Paret G, et al. 2011. Point of care testing in children undergoing cardiopulmonary bypass. Pediatr Blood Cancer 56:794–798.
   PubMed Web of Science ®Google Scholar
• van Werkum JW, Bouman HJ, Breet NJ, ten Berg JM, Hackeng CM. 2010. The Cone-and-Plate(let) analyzer is not suitable to monitor clopidogrel therapy: a comparison with the flowcytometric VASP assay and optical aggregometry. Thromb Res 126:44–49.
   PubMed Web of Science ®Google Scholar
• Vankoningsloo S, Piret JP, Saout C, Noel F, Mejia J, Zouboulis CC, et al. 2010. Cytotoxicity of multi-walled carbon nanotubes in three skin cellular models: effects of sonication, dispersive agents and corneous layer of reconstructed epidermis. Nanotoxicology 4:84–97.
   PubMed Web of Science ®Google Scholar
• Zuo L, Wei W, Morris M, Wei J, Gorbounov M, Wei C. 2007. New technology and clinical applications of nanomedicine. Med Clin North Am 91:845–862.
   PubMed Web of Science ®Google Scholar