Identifying contact-mediated, localized toxic effects of MWCNT aggregates on epithelial monolayers: a single-cell monitoring toxicity assay

References

• American Society for Testing and Materials. 1985. Methods of test for zeta potential of colloids in water and waste water. ASTM Standard D4187–82
   Google Scholar
• Carrero-Sanchez JC, Elias AL, Mancilla R, Arrellin G, Terrones H, Laclette JP, Terrones M. 2006. Biocompatibility and toxicological studies of carbon nanotubes doped with nitrogen. Nano Lett 6:1609–16
   PubMed Web of Science ®Google Scholar
• Casey A, Herzog E, Lyng FM, Byrne HJ, Chambers G, Davoren M. 2008. Single walled carbon nanotubes induce indirect cytotoxicity by medium depletion in A549 lung cells. Toxicol Lett 179:78–84
   PubMed Web of Science ®Google Scholar
• Cereijido M, Contreras RG, Shoshani L, Flores-Benitez D, Larre I. 2008. Tight junction and polarity interaction in the transporting epithelial phenotype. Biochim Biophys Acta 1778:770–93
   PubMed Web of Science ®Google Scholar
• Cui D, Tian F, Ozkan CS, Wang M, Gao H. 2005. Effect of single wall carbon nanotubes on human HEK293 cells. Toxicol Lett 155:73–85
   PubMed Web of Science ®Google Scholar
• Daum N, Neumeyer A, Wahl B, Bur M, Lehr CM. 2009. In vitro systems for studying epithelial transport of macromolecules. Methods Mol Biol 480:151–64
   PubMedGoogle Scholar
• Donaldson K, Aitken R, Tran L, Stone V, Duffin R, Forrest G, Alexander A. 2006. Carbon nanotubes: a review of their properties in relation to pulmonary toxicology and workplace safety. Toxicol Sci 92:5–22
   PubMed Web of Science ®Google Scholar
• Donaldson K, Murphy FA, Duffin R, Poland CA. 2010. Asbestos, carbon nanotubes and the pleural mesothelium: a review of the hypothesis regarding the role of long fibre retention in the parietal pleura, inflammation and mesothelioma. Part Fibre Toxicol 7:5. doi: 10.1186/1743-8977-7-5
   PubMed Web of Science ®Google Scholar
• Dong C, Kashon ML, Lowry D, Dordick JS, Reynolds SH, Rojanasakul Y, et al. 2013. Exposure to carbon nanotubes leads to changes in the cellular biomechanics. Adv Healthc Mater 2:945–51
   PubMed Web of Science ®Google Scholar
• Elgrabli D, Abella-Gallart S, Robidel F, Rogerieux F, Boczkowski J, Lacroix G. 2008. Induction of apoptosis and absence of inflammation in rat lung after intratracheal instillation of multiwalled carbon nanotubes. Toxicology 253:131–6
   PubMed Web of Science ®Google Scholar
• Gatti R, Orlandini G, Uggeri J, Belletti S, Galli C, Raspanti M, et al. 2008. Analysis of living cells grown on different titanium surfaces by time-lapse confocal microscopy. Micron 39:137–43
   Google Scholar
• Gilmore AP. 2005. Anoikis. Cell Death Differ 12:1473–7
   PubMed Web of Science ®Google Scholar
• Grainger CI, Greenwell LL, Martin GP, Forbes B. 2009. The permeability of large molecular weight solutes following particle delivery to air-interfaced cells that model the respiratory mucosa. Eur J Pharm Biopharm 71:318–24
   PubMed Web of Science ®Google Scholar
• Holt BD, Short PA, Rape AD, Wang YL, Islam MF, Dahl KN. 2010. Carbon nanotubes reorganize actin structures in cells and ex vivo. ACS Nano 4:4872–8
   PubMedGoogle Scholar
• Hu H, Yu AP, Kim E, Zhao B, Itkis ME, Bekyarova E, Haddon RC. 2005. Influence of the zeta potential on the dispersability and purification of single-walled carbon nanotubes. J Phys Chem B 109:11520–4
   PubMed Web of Science ®Google Scholar
• Inoue K, Koike E, Yanagisawa R, Hirano S, Nishikawa M, Takano H. 2009. Effects of multi-walled carbon nanotubes on a murine allergic airway inflammation model. Toxicol Appl Pharmacol 237:306–16
   PubMed Web of Science ®Google Scholar
• Kayat J, Gajbhiye V, Tekade RK, Jain NK. 2011. Pulmonary toxicity of carbon nanotubes: a systematic report. Nanomedicine 7:40–9
   PubMed Web of Science ®Google Scholar
• Kermanizadeh A, Gaiser BK, Hutchison GR, Stone V. 2012. An in vitro liver model – assessing oxidative stress and genotoxicity following exposure of hepatocytes to a panel of engineered nanomaterials. Part Fibre Toxicol 9:28. doi: 10.1186/1743-8977-9-28
   PubMed Web of Science ®Google Scholar
• Kim JE, Lim HT, Minai-Tehrani A, Kwon JT, Shin JY, Woo CG, et al. 2010. Toxicity and clearance of intratracheally administered multiwalled carbon nanotubes from murine lung. J Toxicol Environ Health A 73:1530–43
   PubMed Web of Science ®Google Scholar
• Kishore AS, Surekha P, Murthy PB. 2009. Assessment of the dermal and ocular irritation potential of multi-walled carbon nanotubes by using in vitro and in vivo methods. Toxicol Lett 191:268–74
   PubMed Web of Science ®Google Scholar
• Lee CK, Shin SR, Mun JY, Han SS, So I, Jeon JH, et al. 2009. Tough supersoft sponge fibers with tunable stiffness from a DNA self-assembly technique. Angew Chem Int Ed 48:5116–20
   Google Scholar
• Li JG, Li WX, Xu JY, Cai XQ, Liu RL, Li YJ, Zhao QF, Li QN. 2007. Comparative study of pathological lesions induced by multiwalled carbon nanotubes in lungs of mice by intratracheal instillation and inhalation. Environ Toxicol 22:415–21
   PubMed Web of Science ®Google Scholar
• Lu J, Rao MP, MacDonald NC, Khang D, Webster TJ. 2008. Improved endothelial cell adhesion and proliferation on patterned titanium surfaces with rationally designed, micrometer to nanometer features. Acta Biomater 4:192–201
   PubMed Web of Science ®Google Scholar
• Ma-Hock L, Treumann S, Strauss V, Brill S, Luizi F, Mertler M, et al. 2009. Inhalation toxicity of multiwall carbon nanotubes in rats exposed for 3 months. Toxicol Sci 112:468–81
   PubMed Web of Science ®Google Scholar
• Matter K, Balda MS. 2007. Epithelial tight junctions, gene expression and nucleo-junctional interplay. J Cell Sci 120:1505–11
   PubMed Web of Science ®Google Scholar
• Maynard AD, Baron PA, Foley M, Shvedova AA, Kisin ER, Castranova V. 2004. Exposure to carbon nanotube material: aerosol release during the handling of unrefined single-walled carbon nanotube material. J Toxicol Environ Health A 67:87–107
   PubMed Web of Science ®Google Scholar
• Mercer RR, Scabilloni JF, Hubbs AF, Battelli LA, McKinney W, Friend S, et al. 2013. Distribution and fibrotic response following inhalation exposure to multi-walled carbon nanotubes. Part Fibre Toxicol 10:33. doi: 10.1186/1743-8977-10-33
   PubMed Web of Science ®Google Scholar
• Monteiro-Riviere NA, Inman AO, Zhang LW. 2009. Limitations and relative utility of screening assays to assess engineered nanoparticle toxicity in a human cell line. Toxicol Appl Pharmacol 234:222–35
   PubMed Web of Science ®Google Scholar
• Movia D, Prina-Mello A, Bazou D, Volkov Y, Giordani S. 2011. Screening the cytotoxicity of single-walled carbon nanotubes using Novel 3D tissue-mimetic models. Acs Nano 5:9278–90
   PubMed Web of Science ®Google Scholar
• Muller J, Decordier I, Hoet PH, Lombaert N, Thomassen L, Huaux F, et al. 2008a. Clastogenic and aneugenic effects of multi-wall carbon nanotubes in epithelial cells. Carcinogenesis 29:427–33
   PubMed Web of Science ®Google Scholar
• Muller J, Huaux F, Fonseca A, Nagy JB, Moreau N, Delos M, et al. 2008b. Structural defects play a major role in the acute lung toxicity of multiwall carbon nanotubes: toxicological aspects. Chem Res Toxicol 21:1698–705
   PubMed Web of Science ®Google Scholar
• Muller J, Huaux F, Moreau N, Misson P, Heilier JF, Delos M, et al. 2005. Respiratory toxicity of multi-wall carbon nanotubes. Toxicol Appl Pharmacol 207:221–31
   PubMed Web of Science ®Google Scholar
• Murphy FA, Poland CA, Duffin R, Al-Jamal KT, Ali-Boucetta H, Nunes A, et al. 2011. Length-dependent retention of carbon nanotubes in the pleural space of mice initiates sustained inflammation and progressive fibrosis on the parietal pleura. Am J Pathol 178:2587–600
   PubMed Web of Science ®Google Scholar
• Murray AR, Kisin ER, Tkach AV, Yanamala N, Mercer R, Young SH, et al. 2012. Factoring-in agglomeration of carbon nanotubes and nanofibers for better prediction of their toxicity versus asbestos. Part Fibre Toxicol 9:10. doi: 10.1186/1743-8977-9-10
   PubMed Web of Science ®Google Scholar
• Mutlu GM, Budinger GR, Green AA, Urich D, Soberanes S, Chiarella SE, et al. 2010. Biocompatible nanoscale dispersion of single-walled carbon nanotubes minimizes in vivo pulmonary toxicity. Nano Lett 10:1664–70
   PubMed Web of Science ®Google Scholar
• O'Brien J, Wilson I, Orton T, Pognan F. 2000. Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity. Eur J Biochem 267:5421–6
   PubMedGoogle Scholar
• Park EJ, Cho WS, Jeong J, Yi J, Choi K, Park K. 2009. Pro-inflammatory and potential allergic responses resulting from B cell activation in mice treated with multi-walled carbon nanotubes by intratracheal instillation. Toxicology 259:113–21
   PubMed Web of Science ®Google Scholar
• Pauluhn J. 2009. Comparative pulmonary response to inhaled nanostructures: considerations on test design and endpoints. Inhal Toxicol 21:40–54
   PubMedGoogle Scholar
• Pauluhn J. 2010. Subchronic 13-week inhalation exposure of rats to multiwalled carbon nanotubes: toxic effects are determined by density of agglomerate structures, not fibrillar structures. Toxicol Sci 113:226–42
   PubMed Web of Science ®Google Scholar
• Poland CA, Byrne F, Cho WS, Prina-Mello A, Murphy FA, Davies GL, et al. 2012. Length-dependent pathogenic effects of nickel nanowires in the lungs and the peritoneal cavity. Nanotoxicology 6:899–911
   PubMed Web of Science ®Google Scholar
• Ponti J, Colognato R, Rauscher H, Gioria S, Broggi F, Franchini F, et al. 2010. Colony forming efficiency and microscopy analysis of multi-wall carbon nanotubes cell interaction. Toxicol Lett 197:29–37
   PubMed Web of Science ®Google Scholar
• Porter DW, Hubbs AF, Chen BT, McKinney W, Mercer RR, Wolfarth MG, et al. 2013. Acute pulmonary dose-responses to inhaled multi-walled carbon nanotubes. Nanotoxicology 7:1179–94
   PubMed Web of Science ®Google Scholar
• Pulskamp K, Diabate S, Krug HF. 2007. Carbon nanotubes show no sign of acute toxicity but induce intracellular reactive oxygen species in dependence on contaminants. Toxicol Lett 168:58–74
   PubMed Web of Science ®Google Scholar
• Ravichandran P, Baluchamy S, Sadanandan B, Gopikrishnan R, Biradar S, Ramesh V, et al. 2010. Multiwalled carbon nanotubes activate NF-kappaB and AP-1 signaling pathways to induce apoptosis in rat lung epithelial cells. Apoptosis 15:1507–16
   PubMed Web of Science ®Google Scholar
• Ravichandran P, Periyakaruppan A, Sadanandan B, Ramesh V, Hall JC, Jejelowo O, Ramesh GT. 2009. Induction of apoptosis in rat lung epithelial cells by multiwalled carbon nanotubes. J Biochem Mol Toxicol 23:333–44
   PubMed Web of Science ®Google Scholar
• Reddy AR, Reddy YN, Krishna DR, Himabindu V. 2010. Pulmonary toxicity assessment of multiwalled carbon nanotubes in rats following intratracheal instillation. Environ Toxicol 27:211–19
   PubMed Web of Science ®Google Scholar
• Roebben G, Rasmussen K, Kestens V, Linsinger TPJ, Rauscher H, Emons H, Stamm H. 2013. Reference materials and representative test materials: the nanotechnology case. J Nanopart Res15:1455. doi: 10.1007/s11051-013-1455-2
   Web of Science ®Google Scholar
• Rotoli BM, Bussolati O, Barilli A, Zanello PP, Bianchi MG, Magrini A, et al. 2009. Airway barrier dysfunction induced by exposure to carbon nanotubes in vitro: which role for fiber length? Hum Exp Toxicol 28:361–8
   PubMed Web of Science ®Google Scholar
• Rotoli BM, Bussolati O, Bianchi MG, Barilli A, Balasubramanian C, Bellucci S, Bergamaschi E. 2008. Non-functionalized multi-walled carbon nanotubes alter the paracellular permeability of human airway epithelial cells. Toxicol Lett 178:95–102
   PubMed Web of Science ®Google Scholar
• Ryman-Rasmussen JP, Tewksbury EW, Moss OR, Cesta MF, Wong BA, Bonner JC. 2009. Inhaled multiwalled carbon nanotubes potentiate airway fibrosis in murine allergic asthma. Am J Respir Cell Mol Biol 40:349–58
   PubMed Web of Science ®Google Scholar
• Sakagami M. 2006. In vivo, in vitro and ex vivo models to assess pulmonary absorption and disposition of inhaled therapeutics for systemic delivery. Adv Drug Deliv Rev 58:1030–60
   PubMed Web of Science ®Google Scholar
• Saleh NB, Pfefferle LD, Elimelech M. 2010. Influence of biomacromolecules and humic acid on the aggregation kinetics of single-walled carbon nanotubes. Environ Sci Technol 44:2412–18
   PubMed Web of Science ®Google Scholar
• Salem LB, Bosquillon C, Dailey LA, Delattre L, Martin GP, Evrard B, Forbes B. 2009. Sparing methylation of beta-cyclodextrin mitigates cytotoxicity and permeability induction in respiratory epithelial cell layers in vitro. J Control Release 136:110–16
   PubMed Web of Science ®Google Scholar
• Scholzen T, Gerdes J. 2000. The Ki-67 protein: from the known and the unknown. J Cell Physiol 182:311–22
   PubMed Web of Science ®Google Scholar
• Shvedova AA, Kisin ER, Porter D, Schulte P, Kagan VE, Fadeel B, Castranova V. 2009. Mechanisms of pulmonary toxicity and medical applications of carbon nanotubes: two faces of Janus? Pharmacol Ther 121:192–204
   PubMed Web of Science ®Google Scholar
• Shvedova AA, Pietroiusti A, Fadeel B, Kagan VE. 2012. Mechanisms of carbon nanotube-induced toxicity: focus on oxidative stress. Toxicol Appl Pharmacol 261:121–33
   PubMed Web of Science ®Google Scholar
• Shvedova AA, Tkach AV, Kisin ER, Khaliullin T, Stanley S, Gutkin DW, et al. 2013. Carbon nanotubes enhance metastatic growth of lung carcinoma via up-regulation of myeloid-derived suppressor cells. Small 9:1691–5
   PubMed Web of Science ®Google Scholar
• Simon-Deckers A, Gouget B, Mayne-L'hermite M, Herlin-Boime N, Reynaud C, Carriere M. 2008. In vitro investigation of oxide nanoparticle and carbon nanotube toxicity and intracellular accumulation in A549 human pneumocytes. Toxicology 253:137–46
   PubMed Web of Science ®Google Scholar
• Smart SK, Cassady AI, Lu GQ, Martin DJ. 2006. The biocompatibility of carbon nanotubes. Carbon 44:1034–47
   Web of Science ®Google Scholar
• Teijeiro-Osorio D, Remunan-Lopez C, Alonso MJ. 2009. New generation of hybrid poly/oligosaccharide nanoparticles as carriers for the nasal delivery of macromolecules. Biomacromolecules 10:243–9
   PubMed Web of Science ®Google Scholar
• Thubagere A, Reinhard BM. 2010. Nanoparticle-induced apoptosis propagates through hydrogen-peroxide-mediated bystander killing: insights from a human intestinal epithelium in vitro model. ACS Nano 4:3611–22
   PubMed Web of Science ®Google Scholar
• Vogel V, Sheetz M. 2006. Local force and geometry sensing regulate cell functions. Nat Rev Mol Cell Biol 7:265–75
   PubMed Web of Science ®Google Scholar
• Vogel V, Sheetz MP. 2009. Cell fate regulation by coupling mechanical cycles to biochemical signaling pathways. Curr Opin Cell Biol 21:38–46
   PubMed Web of Science ®Google Scholar
• Wang L, Stueckle TA, Mishra A, Derk R, Meighan T, Castranova V, Rojanasakul Y. 2014. Neoplastic-like transformation effect of single-walled and multi-walled carbon nanotubes compared to asbestos on human lung small airway epithelial cells. Nanotoxicology 8:485–507
   PubMed Web of Science ®Google Scholar
• Worle-Knirsch JM, Pulskamp K, Krug HF. 2006. Oops they did it again! Carbon nanotubes hoax scientists in viability assays. Nano Lett 6:1261–8
   PubMed Web of Science ®Google Scholar