Pulmonary clearance kinetics and extrapulmonary translocation of seven titanium dioxide nano- and submicron materials following intratracheal administration in rats

References

• Bermudez E, Mangum JB, Wong BA, Asgharian B, Hext PM, Warheit DB, Everitt JI. 2004. Pulmonary responses of mice, rats, and hamsters to subchronic inhalation of ultrafine titanium dioxide particles. Toxicol Sci 77:347–57
   PubMed Web of Science ®Google Scholar
• Berthon G. 2002. Aluminium speciation in relation to aluminium bioavailability, metabolism and toxicity. Coord Chem Rev 228:319–41
   Web of Science ®Google Scholar
• Borm PJA, Robbins D, Haubold S, Kuhlbusch T, Fissan H, Donaldson K, et al. 2006. The potential risks of nanomaterials: a review carried out for ECETOC. Part Fibre Toxicol 3:11
   PubMed Web of Science ®Google Scholar
• Brain JD, Knudson DE, Sorokin SP, Davis MA. 1976. Pulmonary distribution of particles given by intratracheal instillation or by aerosol inhalation. Environ Res 11:13–33
   PubMed Web of Science ®Google Scholar
• Fabian E, Landsiedel R, Ma-Hock L, Wiench K, Wohlleben W, van Ravenzwaay B. 2008. Tissue distribution and toxicity of intravenously administered titanium dioxide nanoparticles in rats. Arch Toxicol 82:151–7
   PubMed Web of Science ®Google Scholar
• Ferin J, Oberdörster G, Penney DP. 1992. Pulmonary retention of ultrafine and fine particles in rats. Am J Resp Cell Mol Biol 6:535–42
   PubMed Web of Science ®Google Scholar
• Fisichella M, Berenguer F, Steinmetz G, Auffan M, Rose J, Prat O. 2012a. Intestinal toxicity evaluation of TiO2 degraded surface-treated nanoparticles: a combined physico-chemical and toxicogenomics approach in caco-2 cells. Part Fibre Toxicol 9:18
   PubMed Web of Science ®Google Scholar
• Fisichella M, Berenguer F, Steinmetz G, Auffan M, Rose J, Prat O. 2012b. Reply to comment on Fisichella et al., “Intestinal toxicity evaluation of TiO2 degraded surface-treated nanoparticles: a combined physico-chemical and toxicogenomics approach in Caco-2 cells” by Faust et al. Part Fibre Toxicol 9:39
   PubMed Web of Science ®Google Scholar
• Ichihara G, Li W, Kobayashi T, Ding X, Fujitani Y, Liu Y, et al. (2008). Assessment of exposure and health status in workers handling titanium dioxide. International Conference on Safe Production and Use of Nanomaterials. NANOSAFE 2008, Nov 3–7, Minatec, Greboble, France
   Google Scholar
• Ismagilov ZR, Shikina NV, Mazurkova NA, Tsikoza LT, Tuzikov FV, Ushakov VA, et al. (2012). Synthesis of nanoscale TiO2 and study of the effect of their crystal structure on single cell response. Scientific World J 2012: Article ID 498345
   Google Scholar
• Leong BKJ, Coombs JK, Sabaitis CP, Rop DA, Aaron CS. 1998. Quantitative morphometric analysis of pulmonary deposition of aerosol particles inhaled via intratracheal nebulization, intratracheal instillation or nose-only inhalation in rats. J Appl Toxicol 18:149–60
   PubMed Web of Science ®Google Scholar
• Ma-Hock L, Burkhardt S, Strauss V, Gamer A, Wiench K, van Ravenzwaay B, Landsiedel R. 2009. Development of a short-term inhalation test in the rat using nano-titanium dioxide as a model substance. Inhal Toxicol 21:102–18
   PubMed Web of Science ®Google Scholar
• Morrow PE. 1992. Dust overloading of the lungs - update and appraisal. Toxicol Appl Pharmacol 113:1–12
   PubMed Web of Science ®Google Scholar
• Oberdörster G, Ferin J, Lehnert BE. 1994. Correlation between particle-size, in-vivo particle persistence, and lung injury. Environ Health Perspect 102:173–9
   PubMed Web of Science ®Google Scholar
• Oyabu T, Morimoto Y, Hirohashi M, Horie M, Kambara T, Lee BW, et al. 2013. Dose-dependent pulmonary response of well-dispersed titanium dioxide nanoparticles following intratracheal instillation. J Nanopart Res 15:1600
   Web of Science ®Google Scholar
• Pauluhn J. 2009. Pulmonary toxicity and fate of agglomerated 10 and 40 nm aluminum oxyhydroxides following 4-week inhalation exposure of rats: toxic effects are determined by agglomerated, not primary particle size. Toxicol Sci 109:152–67
   PubMed Web of Science ®Google Scholar
• Porter DW, Wu N, Hubbs AF, Mercer RR, Funk K, Meng F, et al. 2013. Differential mouse pulmonary dose and time course responses to titanium dioxide nanospheres and nanobelts. Toxicol Sci 131:179–93
   PubMed Web of Science ®Google Scholar
• Sager TM, Kommineni C, Castranova V. 2008. Pulmonary response to intratracheal instillation of ultrafine versus fine titanium dioxide: role of particle surface area. Part Fibre Toxicol 5:17
   PubMed Web of Science ®Google Scholar
• Shinohara N, Danno N, Ichinose T, Sasaki T, Fukui H, Honda K, Gamo M. 2014a. Tissue distribution and clearance of intravenously administered titanium dioxide (TiO2) nanoparticles. Nanotoxicology 8:132–41
   PubMed Web of Science ®Google Scholar
• Shinohara N, Oshima Y, Kobayashi T, Imatanaka N, Nakai M, Ichinose T, et al. 2014b. Dose-dependent clearance kinetics of intratracheally administered titanium dioxide nanoparticles in rat lung. Toxicology 325:1–11
   PubMed Web of Science ®Google Scholar
• Silva RM, Teesy C, Franzi L, Weir A, Westerhoff P, Evans JE, Pinkerton KE. 2013. Biological response to nano-scale titanium dioxide (TiO2): role of particle dose, shape, and retention. J Toxicol Environ Heal A 76:953–72
   PubMed Web of Science ®Google Scholar
• van Ravenzwaay B, Landsiedel R, Fabian E, Burkhardt S, Strauss V, Ma-Hock L. 2009. Comparing fate and effects of three particles of different surface properties: nano-TiO2, pigmentary TiO2 and quartz. Toxicol Lett 186:152–9
   PubMed Web of Science ®Google Scholar
• Witschger O, Wrobel R, Bianchi B, Bau S. 2010. Potential for exposure during bagging operations in a plant that produces both pigment grade TiO2 and nano-TiO2 as powders. International Conference on Safe Production and Use of Nanomaterials. Nanosafe 2010, Nov 16–18, Minatec, Greboble, France
   Google Scholar