Compared in vivo toxicity in mice of lung delivered biodegradable and non-biodegradable nanoparticles

References

• Bermudez E, Mangum JB, Wong BA, Asgharian B, Hext PM, Warheit DB, Everitt JI. 2004. Pulmonary responses of mice, rats, and hamsters to subchronic inhalation of ultrafine titanium dioxide particles. Toxicol Sci 77:347–57
   PubMed Web of Science ®Google Scholar
• Bivas-Benita M, Zwier R, Junginger HE, Borchard G. 2005. Non-invasive pulmonary aerosol delivery in mice by the endotracheal route. Eur J Pharm Biopharm 61:214–18
   PubMed Web of Science ®Google Scholar
• Braydich-Stolle LK, Schaeublin NM, Murdock RC, Jiang J, Biswas P, Schlager JJ, Hussain SM. 2009. Crystal structure mediates mode of cell death in TiO2 nanotoxicity. J Nanopart Res 11:1361–74
   Web of Science ®Google Scholar
• Dailey LA, Jekel N, Fink L, Gessler T, Schmehl T, Wittmar M, et al. 2006. Investigation of the proinflammatory potential of biodegradable nanoparticle drug delivery systems in the lung. Toxicol Appl Pharmacol 215:100–8
   PubMed Web of Science ®Google Scholar
• Driscoll KE, Maurer JK. 1991. Cytokine and growth factor release by alveolar macrophages: potential biomarkers of pulmonary toxicity. Toxicol Pathol 19:398–405
   PubMed Web of Science ®Google Scholar
• Fattal E, Tsapis N. 2014. Nanomedicine technology: current achievements and new trends. Clin Transl Imaging 2:77–87
   Google Scholar
• Gally F, Di YP, Smith SK, Minor MN, Liu Y, Bratton DL, et al. 2011. SPLUNC1 promotes lung innate defense against mycoplasma pneumoniae infection in mice. Am J Pathol 178:2159–67
   PubMed Web of Science ®Google Scholar
• Grabowski N, Hillaireau H, Vergnaud J, Santiago LA, Kerdine-Romer S, Pallardy M, et al. 2013. Toxicity of surface-modified PLGA nanoparticles toward lung alveolar epithelial cells. Int J Pharm 454:686–94
   PubMed Web of Science ®Google Scholar
• Grabowski N, Hillaireau H, Vergnaud-Gauduchon J, Nicolas V, Tsapis N, Kerdine-Römer S, Fattal E. 2016. Surface-modified biodegradable nanoparticles impact on cytotoxicity and inflammation response on a co-culture of lung epithelial cells and human-like macrophages. J Biomed Nanotechnol 12:135–46
   Google Scholar
• Hara K, Tsujimoto H, Tsukada Y, Huang CC, Kawashima Y, Tsutsumi M. 2008. Histological examination of PLGA nanospheres for intratracheal drug administration. Int J Pharm 356:267–73
   PubMed Web of Science ®Google Scholar
• Husain M, Saber AT, Guo C, Jacobsen NR, Jensen KA, Yauk CL, et al. 2013. Pulmonary instillation of low doses of titanium dioxide nanoparticles in mice leads to particle retention and gene expression changes in the absence of inflammation. Toxicol Appl Pharm 269:250–62
   PubMed Web of Science ®Google Scholar
• Mansour HM, Rhee YS, Wu X. 2009. Nanomedicine in pulmonary delivery. Int J Nanomedicine 4:299–319
   PubMed Web of Science ®Google Scholar
• Maxeiner JH, Karwot R, Hausding M, Sauer KA, Scholtes P, Finotto S. 2007. A method to enable the investigation of murine bronchial immune cells, their cytokines and mediators. Nat Protoc 2:105–12
   PubMed Web of Science ®Google Scholar
• Mohammad A, Amayreh L, Mazzara J, Reineke J. 2013. Rapid lymph accumulation of polystyrene nanoparticles following pulmonary administration. Pharm Res 30:424–34
   PubMed Web of Science ®Google Scholar
• Mura S, Hillaireau H, Nicolas J, Kerdine-Romer S, Le Droumaguet B, Delomenie C, et al. 2011a. Biodegradable nanoparticles meet the bronchial airway barrier: how surface properties affect their interaction with mucus and epithelial cells. Biomacromolecules 12:4136–43
   PubMed Web of Science ®Google Scholar
• Mura S, Hillaireau H, Nicolas J, Le Droumaguet B, Gueutin C, Zanna S, et al. 2011b. Influence of surface charge on the potential toxicity of PLGA nanoparticles towards Calu-3 cells. Int J Nanomed 6:2591–605
   PubMed Web of Science ®Google Scholar
• Oberdorster G, Oberdorster E, Oberdorster J. 2005. Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles. Environ Health Perspect 113:823–39
   PubMed Web of Science ®Google Scholar
• Oyabu T, Morimoto Y, Hirohashi M, Horie M, Kambara T, Lee B, et al. 2013. Dose-dependent pulmonary response of well-dispersed titanium dioxide nanoparticles following intratracheal instillation. J Nanopart Res 15:1–11
   Web of Science ®Google Scholar
• Panyam J, Labhasetwar V. 2003. Biodegradable nanoparticles for drug and gene delivery to cells and tissue. Adv Drug Deliv Rev 55:329–47
   PubMed Web of Science ®Google Scholar
• Reul R, Tsapis N, Hillaireau H, Sancey L, Mura S, Recher M, et al. 2012. Near infrared labeling of PLGA for in vivo imaging of nanoparticles. Polym Chem 3:694–702
   Web of Science ®Google Scholar
• Saber AT, Jacobsen NR, Mortensen A, Szarek J, Jackson P, Madsen AM, et al. 2012. Nanotitanium dioxide toxicity in mouse lung is reduced in sanding dust from paint. Part Fibre Toxicol 9:4
   PubMed Web of Science ®Google Scholar
• Segel MJ, Aqeilan R, Zilka K, Lorberboum-Galski H, Wallach-Dayan SB, Conner MW, et al. 2005. Effect of IL-2-Bax, a novel interleukin-2-receptor-targeted chimeric protein, on bleomycin lung injury. Int J Exp Pathol 86:279–88
   PubMed Web of Science ®Google Scholar
• Singh RP, Ramarao P. 2013. Accumulated polymer degradation products as effector molecules in cytotoxicity of polymeric nanoparticles. Toxicol Sci 136:131–43
   PubMed Web of Science ®Google Scholar
• Ungaro F, d'Angelo I, Coletta C, d'Emmanuele di Villa Bianca R, Sorrentino R, Perfetto B, et al. 2012. Dry powders based on PLGA nanoparticles for pulmonary delivery of antibiotics: modulation of encapsulation efficiency, release rate and lung deposition pattern by hydrophilic polymers. J Control Release 157:149–59
   PubMed Web of Science ®Google Scholar