Copper nanoparticles exert size and concentration dependent toxicity on somatosensory neurons of rat

References

• Aras MA, Hartnett KA, Aizenman E. 2008. Assessment of cell viability in primary neuronal cultures. Curr Protoc Neurosci 44:7.18–7.18.15.
   Google Scholar
• Arciello M, Rotilio G, Rossi L. 2005. Copper-dependent toxicity in SH-SY5Y neuroblastoma cells involves mitochondrial damage. Biochem Biophys Res Commun 327:454–459.
   PubMedGoogle Scholar
• Bertinato J, L'Abbe MR. 2004. Maintaining copper homeostasis: Regulation of copper-trafficking proteins in response to copper deficiency or overload. J Nutr Biochem 15:316–322.
   PubMed Web of Science ®Google Scholar
• Brooking J, Davis SS, Illum L. 2001. Transport of nanoparticles across the rat nasal mucosa. J Drug Target 9:267–279.
   PubMed Web of Science ®Google Scholar
• Cadenas E, Davies KJ. 2000. Mitochondria free radical generation, oxidative stress and aging. Free Radic Biol Med 29:222–230.
   PubMed Web of Science ®Google Scholar
• Cecconi I, Scaloni A, Rastelli G, Moroni M, Vilardo PG, Costantino L, Cappiello M, Garland D, Carper D, Petrash JM, Del Corso A, Mura U. 2002. Oxidative modification of aldose reductase by copper ion. Definition of the metal-protein interaction mechanism. J Biol Chem 277:42017–42027.
   PubMed Web of Science ®Google Scholar
• Chen Z, Meng H, Xing G, Chen C, Zhao Y, Jia G, Wang T, Yuan H, Ye C, Zhao F, Chai Z, Zhu C, Fang X, Ma B, Wan L. 2006. Acute toxicological effects of copper nanoparticles in vivo. Toxicol Lett 163:109–120.
   PubMed Web of Science ®Google Scholar
• Chen Z, Meng H, Yuan H, Xing G, Chen C, Zhao F, Wang Y, Zhang C, Zhao Y. 2007. Identification of target of copper nanoparticles with ICP-MS technique. J Radioanalytical Nuclear Chem 272:599–603.
   Web of Science ®Google Scholar
• Gaetke LM, Chow CK. 2003. Copper toxicity, oxidative stress, and antioxidant nutrients. Toxicology 189:147–163.
   PubMed Web of Science ®Google Scholar
• Curtis J, Greenberg M, Kester J, Phillips S, Krieger G. 2006. Nanotechnology and nanotoxicity: A primer for clinicians. Toxicol Rev 25:245–260.
   PubMedGoogle Scholar
• Evans GW. 1973. Copper homeostasis in the mammalian system. Physiol Rev 53:535–570.
   PubMed Web of Science ®Google Scholar
• Freedman JH, Ciriola MR, Peisach J. 1989. The role of glutathione in copper metabolish and toxicity. J Biol Chem 264:5598–5605.
   PubMed Web of Science ®Google Scholar
• Galhardi CM, Diniz YS, Faine LA, Rodrigues HG, Burneiko RC, Ribas BO, Novelli EL. 2004. Toxicity of copper intake: Lipid profile, oxidative stress and susceptibility to renal dysfunction. Food Chem Toxicol 42:2053–2060.
   PubMed Web of Science ®Google Scholar
• Griffitt R, Weil R, Kelly H, Denslow ND, Powers K, Taylor D, Barber DS. 2007. Exposure to copper nanoparticles causes gill injury and acute lethality in Zebrafish (Danio rerio). Environ Sci Technol 41:8178–8186.
   PubMed Web of Science ®Google Scholar
• Gotz ME, Koutsilieri E, Riederer P, Ceccatelli S, Dare E. 2002. Methylmercury induces neurite degeneration in primary culture of mouse dopaminergic mesencephalic cells. J Neural Transm 109:597–605.
   PubMedGoogle Scholar
• Guo K, Pand Q, Wang L, Fang S. 2002. Nano-scale copper-coated graphite as anode material for lithium-ion batteries. J Appl Electrochem 32:679–685.
   Web of Science ®Google Scholar
• Halliwell B, Gutteridge JM. 1990. Role of free radicals and catalytic metals ions in human disease: An overview. Methods Enzymol 186:1–85.
   PubMed Web of Science ®Google Scholar
• Hoet PH, Bruske-Hohlfeld I, Salata OV. 2004. Nanoparticles-known and unknown health risks. J Nanobiotechnol 2:12–27.
   PubMedGoogle Scholar
• Hultberg B, Andersson A, Isaksson A. 1997. Copper ions differ from other thiol reactive metal ions in their effects on the concentration and redox status of thiols in HeLa cell cultures. Toxicology 117:89–97.
   PubMedGoogle Scholar
• Hussain SM, Hess KL, Gearhart JM, Geiss KT, Schlager JJ. 2005. In vitro toxicity of nanoparticles in BRL 3A rat liver cells. Toxicology In Vitro 19:975–983.
   PubMed Web of Science ®Google Scholar
• Jeon KJ, Jeong JV, Jue DM. 2000. Thiol reactive metal compounds inhibit NFkB by blocking IkB kinase. J Immunol 164:5981–5989.
   PubMed Web of Science ®Google Scholar
• Kawata M, Suzuki KT. 1983. Relation between metal and glutathione concentrations in mouse liver after cadmium, zinc or copper loading. Toxicol Lett 15:131–137.
   PubMedGoogle Scholar
• Li F, Zhou X, Zhu J, Ma J, Huang X, Wong ST. 2007. High content image analysis for human H4 neuroglioma cells exposed to CuO nanoparticles. BMC Biotechnol 7:66–76.
   PubMed Web of Science ®Google Scholar
• Li W, Kagan HM, Chou IN. 1994. Alterations in cytoskeletal organization and homeostasis of cellular thiols in cadmium-resistant cells. Toxicol Appl Pharmacol 126:114–123.
   PubMedGoogle Scholar
• Liu G, Li X, Qin B, Xing D, Guo Y, Fan R. 2004. Investigation of the mending effect and mechanism of copper nanoparticles on a tribologically stressed surface. Tribol Lett 17:961–966.
   Web of Science ®Google Scholar
• Mattie MD, Freedman JH. 2001. Protective effects of aspirin and vitamin E (alpha-tocopherol) against copper and cadmium-induced toxicity. Biochem Biophys Res Comm 285:921–925.
   PubMed Web of Science ®Google Scholar
• Meng H, Chen Z, Xing G, Yuan H, Chen C, Zhao F, Zhang C, Wang Y, Zhao Y. 2007a. Ultra-high reactivity and grave nanotoxicity of copper nanoparticles. J Radioanalyt Nuclear Chem 271:595–598.
   Google Scholar
• Meng H, Chen Z, Xing G, Yuan H, Chen C, Zhao F, Zhang C, Zhao Y. 2007b. Ultra-high reactivity provokes nanotoxicity: Explanation of oral toxicity of nano-copper particles. Toxicol Lett 175:102–110.
   PubMed Web of Science ®Google Scholar
• Munirathinam S, Lakshmana MK, Raju TR. 1996. (-) deprenyl attenuates aluminium induced neurotoxicity in primary cortical cultures. Neurodegeneration 5:161–167.
   PubMedGoogle Scholar
• Murdock RC, Braydich-Stolle L, Schrand AM, Schlagger JJ, Hussain SM. 2008. Characterization of nanomaterials dispersion in solution prior to in vitro exposure using dynamic light scattering technique. Tox Sci 101:239–253.
   PubMed Web of Science ®Google Scholar
• Nalbandyan RM. 1983. Copper in brain. Neurochem Res 8:1211–1232.
   PubMedGoogle Scholar
• Nel A, Xia T, Madler L, Li N. 2006. Toxic potential of materials at the nanolevel. Science 311:622–627.
   PubMed Web of Science ®Google Scholar
• Oberdörster G, Oberdörster E, Oberdörster J. 2005. Nanotoxicology: An emerging discipline evolving from studies of ultrafine particles. Environ Health Perspect 113:823–839.
   PubMed Web of Science ®Google Scholar
• Praetorius M, Brunner C, Lehnert B, Klingmann C, Schmidt H, Staecker H, Schick B. 2007. Transsynaptic delivery of nanoparticles to the central auditory nervous system. Acta Otolaryngol 2007;127:486–490.
   PubMed Web of Science ®Google Scholar
• Pourahmad J, O'Brien PJ. 2000. A comparison of hepatocyte cytotoxic mechanisms for Cu2+ and Cd2+. Toxicology 143:263–273.
   PubMed Web of Science ®Google Scholar
• Saris NE, Skulskii IA. 1991. Interaction of copper with mitochondria. Acta Chem Scand 45:1042–1046.
   PubMedGoogle Scholar
• Sheline CT, Choi DW. 2004. Cu2+ toxicity inhibition of mitochondrial dehydrogenases in vitro and in vivo. Ann Neurol 55:645–653.
   PubMed Web of Science ®Google Scholar
• Sokol RJ, Twedt D, McKim JM Jr, Deveraux MW, Karrer FM, Kam I, von Steigman G, Narkewicz MR, Bacon BR, Britton RS. 1994. Oxidant injury to hepatic mitochondria in patients with Wilson's disease and Bedlington terriers with copper toxicosis. Gastroenterology 107:1788–1798.
   PubMed Web of Science ®Google Scholar
• Sternlieb I. 1980. Copper and the liver. Gastroenterology 78: 1615–1628.
   PubMed Web of Science ®Google Scholar
• Thornburg LP, Beissenherz M, Dolan M, Raisbeck MF. 1985. Histochemical demonstration of copper and copper-associated protein in the canine liver. Vet Pathol 22:327–332.
   PubMed Web of Science ®Google Scholar
• Wang J, Rahman MF, Duhart HM, Newport GD, Patterson TA, Murdock RC, Hussain SM, Schlager JJ, Ali SF. 2009. Expression changes of dopaminergic system related genes in PC 12 cells induced by manganese, silver and copper nanoparticles. NeuroTox (in press).
   Google Scholar
• Yang J, Okamoto T, Ichino R, Bessho T, Satake S, Okido M. 2006. A simple way for preparing antioxidation nano-copper powders. Chem Lett 35:648–649.
   Web of Science ®Google Scholar
• Valko M, Morris H, Cronin MTD. 2005. Metals, toxicity and oxidative stress. Curr Med Chem 12:1161–1208.
   PubMed Web of Science ®Google Scholar