Parathyroid hormone PTH(1–34) increases the volume, mineral content, and mechanical properties of regenerated mineralizing tissue after distraction osteogenesis in rabbits

References

• Aleksyniene R, Eckardt H, Bundgaard K, Lind M, Hvid I. Effects of parathyroid hormone on newly regenerated bone during distraction osteogenesis in a rabbit tibial lengthening model. A pilot study.. Medicina (Kaunas) 2006; 42:38–48.
   PubMedGoogle Scholar
• Alkhiary YM, Gerstenfeld LC, Krall E, Westmore M, Sato M, Mitlak BH, Einhorn TA. Enhancement of experimental fracture-healing by systemic administration of recombinant human parathyroid hormone (PTH 1-34).. J Bone Joint Surg (Am) 2005; 87:731–41.
   PubMed Web of Science ®Google Scholar
• Andreassen TT, Ejersted C, Oxlund H. Intermittent parathyroid hormone (1-34) treatment increases callus formation and mechanical strength of healing rat fractures.. J Bone Miner Res 1999; 14:960–8.
   PubMed Web of Science ®Google Scholar
• Andreassen TT, Fledelius C, Ejersted C, Oxlund H. Increases in callus formation and mechanical strength of healing fractures in old rats treated with parathyroid hormone.. Acta Orthop Scand 2001; 72:304–7.
   PubMed Web of Science ®Google Scholar
• Barnes GL, Kakar S, Vora S, Morgan EF, Gerstenfeld LC, Einhorn TA. Stimulation of fracture-healing with systemic intermittent parathyroid hormone treatment.. J Bone Joint Surg Am (Suppl 1) 2008; 90:120–7.
   PubMed Web of Science ®Google Scholar
• Bundgaard K. Stimulation of distraction osteogenesis. Mechanical and bone density imaging studies in the rabbit. 1999. Faculty of Health Sciences, University of Aarhus.
   Google Scholar
• Dobning H, Turner RT. Evidence that intermittent treatment with parathyroid hormone increases bone formation in adult rats by activation of bone lining cells.. Endocrinology 1995; 136:3632–8.
   Google Scholar
• Eckardt H. Growth factor enhancement of bone formation. Experimental models in the rabbits. 2003. Faculty of Health Sciences, University of Aarhus.
   Google Scholar
• Friedl G, Turner RT, Evans GL, Dobnig H. Intermittent parathyroid hormone (PTH) treatment and age-dependent effects on rat cancellous bone and mineral metabolism.. J Orthop Res 2007; 25:1454–64.
   PubMed Web of Science ®Google Scholar
• Gabet Y, Muller R, Levy J, Dimarchi R, Chorev M, Bab I, Kohavi D. Parathyroid hormone 1-34 enhances titanium implant anchorage in low-density trabecular bone: a correlative micro-computed tomographic and biomechanical analysis.. Bone 2006; 39:276–82.
   PubMed Web of Science ®Google Scholar
• Hamann KL, Lane NE. Parathyroid hormone update.. Rheum Dis Clin North Am 2006; 32:703–19.
   PubMed Web of Science ®Google Scholar
• Hirano T, Burr DB, Turner CH, Sato M, Cain RL, Hock JM. Anabolic effects of human biosynthetic parathyroid hormone fragment (1-34), LY333334, on remodeling and mechanical properties of cortical bone in rabbits.. J Bone Miner Res 1999; 14:536–45.
   PubMed Web of Science ®Google Scholar
• Holzer G, Majeska RJ, Lundy MW, Hartke JR, Einhorn TA. Parathyroid hormone enhances fracture healing. A preliminary report.. Clin Orthop 1999; :366258–63.
   PubMed Web of Science ®Google Scholar
• Li M, Liang H, Shen Y, Wronski TJ. Parathyroid hormone stimulates cancellous bone formation at skeletal sites regardless of marrow composition in ovariectomized rats.. Bone 1999; 24:95–100.
   PubMed Web of Science ®Google Scholar
• Li R, Saleh M, Yang L, Coulton L. Radiographic classification of osteogenesis during bone distraction.. J Orthop Res 2006; 24:339–47.
   PubMed Web of Science ®Google Scholar
• Mashiba T, Burr DB, Turner CH, Sato M, Cain RL, Hock JM. Effects of human parathyroid hormone (1-34), LY333334, on bone mass, remodeling, and mechanical properties of cortical bone during the first remodeling cycle in rabbits.. Bone 2001; 28:538–47.
   PubMed Web of Science ®Google Scholar
• Mosekilde L, Thomsen JS, McOsker JE. No loss of biomechanical effects after withdrawal of short-term PTH treatment in an aged, osteopenic, ovariectomized rat model.. Bone 1997; 20:429–37.
   PubMed Web of Science ®Google Scholar
• Oxlund H, Ejersted C, Andreassen TT, Torring O, Nilsson MH. Parathyroid hormone (1-34) and (1-84) stimulate cortical bone formation both from periosteum and endosteum.. Calcif Tissue Int 1993; 53:394–9.
   PubMed Web of Science ®Google Scholar
• Paavolaainen P. Studies on mechanical strength of bone. I. Torsional strength of normal rabbit tibio-fibular bone.. Acta Orthop Scand 1978; 49:497–505.
   PubMedGoogle Scholar
• Richards M, Goulet JA, Schaffler MB, Goldstein SA. 1999; Temporal and spatial characterization of regenerate bone in the lengthened rabbit tibia.. J Bone Miner Res 1999; 14:1978–86.
   PubMed Web of Science ®Google Scholar
• Rubin MR, Cosman F, Lindsay R, Bilezikian JP. The anabolic effects of parathyroid hormone.. Osteoporos Int 2002; 13:267–77.
   PubMed Web of Science ®Google Scholar
• Schumacher B, Keller J, Hvid I. Distraction effects on muscle. Leg lengthening studied in rabbits.. Acta Orthop Scand 1994; 65:647–50.
   PubMed Web of Science ®Google Scholar
• Seebach C, Skripitz R, Andreassen TT, Aspenberg P. Intermittent parathyroid hormone (1-34) enhances mechanical strength and density of new bone after distraction osteogenesis in rats.. J Orthop Res 2004; 22:472–8.
   PubMed Web of Science ®Google Scholar
• Skripitz R, Aspenberg P. Implant fixation enhanced by intermittent treatment with parathyroid hormone.. J Bone Joint Surg (Br) 2001; 83:437–40.
   PubMed Web of Science ®Google Scholar
• Skripitz R, Andreassen TT, Aspenberg P. 2000a; Parathyroid hormone (1-34) increases the density of rat cancellous bone in a bone chamber. A dose-response study.. J Bone Joint Surg (Br) 82:138–41.
   PubMedGoogle Scholar
• Skripitz R, Andreassen TT, Aspenberg P. 2000b; Strong effect of PTH (1-34) on regenerating bone: a time sequence study in rats.. Acta Orthop Scand 71:619–24.
   PubMed Web of Science ®Google Scholar
• Thomas T. Intermittent parathyroid hormone therapy to increase bone formation.. Joint Bone Spine 2006; 73:262–9.
   PubMed Web of Science ®Google Scholar
• Turner CH, Burr DB. Basic biomechanical measurements of bone: a tutorial.. Bone 1993; 14:595–608.
   PubMed Web of Science ®Google Scholar
• Watson P, Lazowski D, Han V, Fraher L, Steer B, Hodsman A. Parathyroid hormone restores bone mass and enhances osteoblast insulin-like growth factor I gene expression in ovariectomized rats.. Bone 1995; 16:357–65.
   PubMed Web of Science ®Google Scholar
• Yasui N, Kojimoto H, Sasaki K, Kitada A, Shimizu H, Shimomura Y. Factors affecting callus distraction in limb lengthening.. Clin Orthop 1993; :29355–60.
   PubMed Web of Science ®Google Scholar