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Acta Orthopaedica Volume 82, 2011 - Issue 3
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Research Article

Biofilms in chronic diabetic foot ulcers—a study of 2 cases

Daniëlle NeutDepartments of Biomedical Engineering;Orthopaedic Surgery, University Medical Center Groningen and University of Groningen, Groningen, the NetherlandsCorrespondence[email protected]
,
Elvira JA Tijdens-CreusenOrthopaedic Surgery, University Medical Center Groningen and University of Groningen, Groningen, the Netherlands
,
Sjoerd K BulstraOrthopaedic Surgery, University Medical Center Groningen and University of Groningen, Groningen, the Netherlands
,
Henny C van der MeiDepartments of Biomedical Engineering
&
Henk J BusscherDepartments of Biomedical Engineering
Pages 383-385 | Received 14 Sep 2010, Accepted 28 Feb 2011, Published online: 11 May 2011

  • http://www.diabetesatlas.org/content/europe
  • Adler AI, Boyko EJ, Ahroni JH, Smith DG. Lower-extremity amputation in diabetes.The independent effects of peripheral vascular disease, sensory neuropathy, and foot ulcers. Diabetes Care 1999; 22: 1029-35.
  • Boulton AJ, Vileikyte L, Ragnarson-Tennvall G, Apelqvist J. The global burden of diabetic foot disease. Lancet 2005; 366: 1719-24.
  • Costerton JW. Biofilm theory can guide the treatment of device-related orthopedic infections. Clin Orthop 2005; (437): 7-11.
  • Davis SC, Martinez L, Kirsner R. The diabetic foot: the importance of biofilms and wound bed preparation. Curr Diab Rep 2006; 6: 439-45.
  • Dowd SE, Wolcott RD, Sun Y, McKeehan T, Smith E, Rhoads D. Polymicrobial nature of chronic diabetic foot ulcer biofilm infections determined using bacterial tag encoded FLX amplicon pyrosequencing (bTEFAP).PLoS ONE. 2008a; 3: e3326.
  • Dowd SE, Sun Y, Secor PR, Rhoads DD, Wolcott BM, James GA, Wolcott RD. Survey of bacterial diversity in chronic wounds using Pyrosequencing, DGGE, and full ribosome shotgun sequencing. BMC Microbiol 2008b; 8: 43.
  • Hall-Stoodley L, Hu FZ, Gieseke A, Nistico L, Nguyen D, Hayes J, Forbes M, Greenberg DP, Dice B, Burrows A, Wackym PA, Stoodley P, Post JC, Ehrlich GD, Kerschner JE. Direct detection of bacterial biofilms on the middle-ear mucosa of children with chronic otitis media. JAMA 2006; 296: 202-11.
  • James GA, Swogger E, Wolcott R, Pulcini E, Secor P, Sestrich J, Costerton JW, Stewart PS. Biofilms in chronic wounds. Wound Repair Regen 2008; 16: 37-44.
  • Kirketerp-Møller K, Jensen PØ, Fazli M, Madsen KG, Pedersen J, Moser C, Tolker-Nielsen T, Høiby N, Givskov M, Bjarnsholt T. Distribution, organization, and ecology of bacteria in chronic wounds. J Clin Microbiol 2008; 46: 2717-22.
  • Nielsen PH, Frølund B, Keiding K. Changes in the composition of extracellular polymeric substances in activated sludge during anaerobic storage. Appl Microbiol Biotechnol 1996; 44: 823-30.
  • Percival SL, Bowler PG. Biofilms and their potential role in wound healing. Wounds 2004; 16: 234-40.
  • Pollard T. A new vision for wound healing. J Wound Care 2008; 17: 141.
  • Serralta VW, Harrison-Balestra C, Cazzaniga AL, Davis SC, Mertz PM. Lifestyles of bacteria in wounds: presence of biofilms? Wounds 2001; 13: 29-34.
  • Stewart PS, Costerton JW. Antibiotic resistance of bacteria in biofilms. Lancet 2001; 358: 135-8.
  • Stoodley P, Nistico L, Johnson S, Lasko LA, Baratz M, Gahlot V, Ehrlich GD, Kathju S. Direct demonstration of viable Staphylococcus aureus biofilms in an infected total joint arthroplasty. A case report. J Bone Joint Surg (Am) 2008; 90: 1751-8.
  • Tsuneda S, Aikawa H, Hayashi H, Yuasa A, Hirata A. Extracellular polymeric substances responsible for bacterial adhesion onto solid surface. FEMS Microbiol Lett 2003; 223: 287-92.
  • Walenkamp GH. Gentamicin PMMA beads and other local antibiotic carriers in two-stage revision of total knee infection: a review. J Chemother 2001; 1: 66-72.
  • Wolcott RD, Rhoads DD. A study of biofilm-based wound management in subjects with critical limb ischaemia. J Wound Care 2008; 17: 145-55.

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