Advanced search
Publication Cover
Acta Orthopaedica Volume 83, 2012 - Issue 5
Journal homepage
2,040
Views
61
CrossRef citations to date
0
Altmetric
Cadaver bone

Embalmed and fresh frozen human bones in orthopedic cadaveric studies: which bone is authentic and feasible?

A mechanical study

Tobias ToppDepartments of Trauma, Hand and Reconstructive SurgeryCorrespondence[email protected]
,
Thorben MüllerDepartments of Trauma, Hand and Reconstructive Surgery
,
Sebastian HussDepartment of Pathology, Bonn University Hospital, Bonn, Germany
,
Peter Herbert KannGastroenterology, Section of Endocrinology
,
Eberhard WeiheInstitutes of Anatomy and Cell Biology, University Hospital Giessen and Marburg, Marburg
,
Steffen RuchholtzDepartments of Trauma, Hand and Reconstructive Surgery
&
Ralph Peter ZettlDepartments of Trauma, Hand and Reconstructive Surgery
 show all
Pages 543-547 | Received 02 Mar 2012, Accepted 11 Jun 2012, Published online: 14 Sep 2012

  • ASTM.Designation: F1691-96. Standard test method for determining axial pullout strength of medical bone screws. Book of ASTM Standards 1996;Philadelphia, PA: American Society for Testing and Materials.
  • Battula S, Schoenfeld AJ, Sahai V, Vrabec GA, Tank J, Njus GO. The effect of pilot hole size on the insertion torque and pullout strength of self-tapping cortical bone screws in osteoporotic bone. J Trauma 2008; 64 (4): 990-5.
  • Burkhart KJ, Nowak TE, Blum J, Kuhn S, Welker M, Sternstein W, Mueller LP, Rommens PM. Influence of formalin fixation on the biomechanical properties of human diaphyseal bone. Biomed Tech (Berl) 2010; 55 (6): 361-5.
  • Cristofolini L, Viceconti M, Cappello A, Toni A. Mechanical validation of whole bone composite femur models. J Biomech 1996; 29 (4): 525-35.
  • Currey JD, Brear K, Zioupos P, Reilly GC. Effect of formaldehyde fixation on some mechanical properties of bovine bone. Biomaterials 1995; 16 (16): 1267-71.
  • Goh JC, Ang EJ, Bose K. Effect of preservation medium on the mechanical properties of cat bones. Acta Orthop Scand 1989; 60 (4): 465-7.
  • Linde F, Sorensen HC. The effect of different storage methods on the mechanical properties of trabecular bone. J Biomech 1993; 26 (10): 1249-52.
  • Matter HP, Garrel TV, Bilderbeek U, Mittelmeier W. Biomechanical examinations of cancellous bone concerning the influence of duration and temperature of cryopreservation. J Biomed Mater Res 2001; 55 (1):0-4.
  • McElhaney J, Fogle J, Byars E, Weaver G. Effect of Embalming on the Mechanical Properties of Beef Bone. J Appl Physiol 1964; 19: 1234-6.
  • Muller T, Topp T, Kuhne CA, Gebhart G, Ruchholtz S, Zettl R. The benefit of wire cerclage stabilisation of the medial hinge in intramedullary nailing for the treatment of subtrochanteric femoral fractures: a biomechanical study. Int Orthop 2011; 35 (8): 1237-43.
  • Ohman C, Dall’Ara E, Baleani M, Van Sint Jan S, Viceconti M. The effects of embalming using a 4% formalin solution on the compressive mechanical properties of human cortical bone. Clin Biomech (Bristol. Avon) 2008; 23 (10): 1294-8.
  • Panjabi MM, Krag M, Summers D, Videman T. Biomechanical time-tolerance of fresh cadaveric human spine specimens. J Orthop Res 1985; 3 (3): 292-300.
  • Park K, Kim K, Choi YS. Comparison of mechanical rigidity between plate augmentation leaving the nail in situ and interlocking nail using cadaveric fracture model of the femur. Int Orthop 2010; 35 (4): 581-5.
  • Pauwels F. Der Schenkelhalsbruch. Ein mechanisches Problem. Beilagheft Z Orthop Chir 1935;Stuttgart:Enke 63.
  • Pelker RR, Friedlaender GE, Markham TC. Biomechanical properties of bone allografts. Clin Orthop 1983; (174): 54-7.
  • Roe SC, Pijanowski GJ, Johnson AL. Biomechanical properties of canine cortical bone allografts: effects of preparation and storage. Am J Vet Res 1988; 49 (6): 873-7.
  • Schoenfeld AJ, Battula S, Sahai V, Vrabec GA, Corman S, Burton L, Njus GO. Pullout strength and load to failure properties of self-tapping cortical screws in synthetic and cadaveric environments representative of healthy and osteoporotic bone. J Trauma 2008; 64 (5): 1302-7.
  • Sonstegard DA, Matthews B. Mechanical property dependence on storage technique and locale of knee joint trabecular bone. Trans orthop Res Soc 1977; 2:283.
  • Sterling TR, Pope DS, Bishai WR, Harrington S, Gershon RR, Chaisson RE. Transmission of Mycobacterium tuberculosis from a cadaver to an embalmer. N Engl J Med 2000; 342 (4): 246-8.
  • van Haaren EH, van der Zwaard BC, van der Veen AJ, Heyligers IC, Wuisman PI, Smit TH. Effect of long-term preservation on the mechanical properties of cortical bone in goats. Acta Orthop 2008; 79 (5): 708-16.
  • Wingerter S, Calvert G, Tucci M, Benghuzzi H, Russell G, Puckett A. Mechanical strength repercussions of various fixative storage methods on bone. Biomed Sci Instrum 2006; 42: 290-5.
  • Zdero R, Olsen M, Bougherara H, Schemitsch EH. Cancellous bone screw purchase: a comparison of synthetic femurs, human femurs, and finite element analysis. Proc Inst Mech Eng H 2008; 222 (8): 1175-83.
  • Zech S, Goesling T, Hankemeier S, Knobloch K, Geerling J, Schultz-Brunn K, Krettek C, Richter M. Differences in the mechanical properties of calcaneal artificial specimens, fresh frozen specimens, and embalmed specimens in experimental testing. Foot Ankle Int 2006; 27 (12): 1126-36.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.