2,131
Views
26
CrossRef citations to date
0
Altmetric
Miscellaneous

A single topical dose of erythropoietin applied on a collagen carrier enhances calvarial bone healing in pigs

, , , , , , & show all
Pages 201-209 | Received 21 Aug 2013, Accepted 02 Dec 2013, Published online: 25 Feb 2014

  • Baas J. Adjuvant therapies of bone graft around non-cemented experimental orthopaedic implants. Acta Orthop 2008; 79 (suppl 330): 2-43.
  • Bleuel H, Hoffmann R, Kaufmann B, Neubert P, Ochlich PP, Schaumann W. Kinetics of subcutaneous versus intravenous epoetin-beta in dogs, rats and mice. Pharmacology 1996; 52(5): 329-38.
  • Bozlar M, Kalaci A, Aslan B, Baktiroglu L, Yanat AN, Tasci A. Effects of erythropoietin on fracture healing in rats. Saudi Med J 2006; 27(8):1267-9.
  • Chen M, Le D QS, Baatrup A, Nygaard JV, Hein S, Bjerre L, Kassem M, Zou X, Bünger C. Self-assembled composite matrix in a hierarchical 3-D scaffold for bone tissue engineering. Acta Biomater 2011; 7(5): 2244-55.
  • Compston JE, Vedi S, Stellon AJ. Inter-observer and intra-observer variation in bone histomorphometry. Calcif Tissue Int 1986; 38(2): 67-70.
  • Doube M, Kłosowski MM, Arganda-Carreras I, Cordelières FP, Dougherty RP, Jackson JS, Schmid B, Hutchinson JR, Shefelbine SJ. BoneJ: Free and extensible bone image analysis in ImageJ. Bone 2010; 47(6):1076–9.
  • Ehrenreich H, Weissenborn K, Prange H, Schneider D, Weimar C, Wartenberg K, Schellinger PD, Bohn M, Becker H, Wegrzyn M, Jähnig P, Herrmann M, Knauth M, Bähr M, Heide W, Wagner A, Schwab S, Reichmann H, Schwendemann G, Dengler R, Kastrup A, Bartels C. Recombinant human erythropoietin in the treatment of acute ischemic stroke. Stroke 2009; 40(12): e647–56.
  • Erben RG. Embedding of bone samples in methylmethacrylate: an improved method suitable for bone histomorphometry, histochemistry, and immunohistochemistry. J Histochem Cytochem 1997; 45: 307.
  • Garcia P, Speidel V, Scheuer C, Laschke MW, Holstein JH, Histing T, Pohlemann T, Menger MD. Low dose erythropoietin stimulates bone healing in mice. J Orthop Res 2011; 29(2): 165-72.
  • Gundersen HJ, Bendtsen TF, Korbo L, Marcussen N, Møller A, Nielsen K, Nyengaard JR, Pakkenberg B, Sørensen FB, Vesterby A. Some new, simple and efficient stereological methods and their use in pathological research and diagnosis. APMIS 1988; 96(5): 379-94.
  • Holstein JH, Menger MD, Scheuer C, Meier C, Culemann U, Wirbel RJ, Garcia P, Pohlemann T. Erythropoietin (EPO): EPO-receptor signaling improves early endochondral ossification and mechanical strength in fracture healing. Life Sci 2007; 80(10):893-900.
  • Holstein JH, Orth M, Scheuer C, Tami A, Becker SC, Garcia P, Histing T, Mörsdorf P, Klein M, Pohlemann T, Menger MD. Erythropoietin stimulates bone formation, cell proliferation, and angiogenesis in a femoral segmental defect model in mice. Bone 2011; 49(5):1037-45.
  • Hulbert SF, Young FA, Mathews RS, Klawitter JJ, Talbert CD, Stelling FH. Potential of ceramic materials as permanently implantable skeletal prostheses. J Biomed Mater Res 1970; 4(3): 433-56.
  • Jensen J, Rölfing JHD, Le D QS, Kristiansen AA, Nygaard JV, Hokland LB, Bendtsen M, Kassem M, Lysdahl H, Bünger C. Surface-modified functionalized PCL scaffolds for bone repair: in vitro and in vivo experiments. J Biomed Mater Res A 2013. Available from: http://doi.org/10.1002/jbm.a. 34970.
  • Karageorgiou V, Kaplan D. Porosity of 3D biomaterial scaffolds and osteogenesis. Biomaterials 2005; 26(27): 5474-91.
  • Kawachi K, Iso Y, Sato T, Wakabayashi K, Kobayashi Y, Takeyama Y, Suzuki H. Effects of erythropoietin on angiogenesis after myocardial infarction in porcine. Heart Vessels 2012; 27(1): 79-88.
  • Kim J, Jung Y, Sun H, Joseph J, Mishra A, Shiozawa Y, Wang J, Krebsbach PH, Taichman RS. Erythropoietin mediated bone formation is regulated by mTOR signaling. J Cell Biochem 2012; 113(1): 220-8.
  • Ozerdem OR, Anlatici R, Bahar T, Kayaselcuk F, Barutcu O, Tuncer I, Sen O. Roles of periosteum, dura, and adjacent bone on healing of cranial osteonecrosis. J Craniofac Surg 2003; 14(3): 371-9.
  • Prasad A, Berger D, Popat K. PCL nanopillars versus nanofibers: a contrast in progenitor cell morphology, proliferation, and fate determination. Adv Eng Mater 2013; 14: B351–B356.
  • Recker RR. Bone histomorphometry: techniques and interpretation. CRC Press, Boca Raton, Florida 1983.
  • Riordan AM, Rangarajan R, Balts JW, Hsu WK, Anderson PA. Reliability of the rabbit postero-lateral spinal fusion model: A meta-analysis. J Orthop Res 2013; 31(8): 1261-9.
  • Rölfing JHD, Bendtsen M, Jensen J, Stiehler M, Foldager CB, Hellfritzsch MB, Bünger C. Erythropoietin augments bone formation in a rabbit posterolateral spinal fusion model. J Orthop Res 2012; 30(7): 1083-8.
  • Rölfing JH, Bünger C. Recommendations regarding the rabbit posterolateral spinal fusion model. J Orthop Res 2013; 31(11): 1860.
  • Rölfing JHD, Baatrup A, Stiehler M, Jensen J, Lysdahl H, Bünger C. The osteogenic effect of erythropoietin on human mesenchymal stromal cells is dose dependent and involves non-hematopoietic receptors and multiple intracellular signaling pathways. Stem Cell Rev 2013. Available from: http://doi.org/10.1007/s12015-013-9476-x.
  • Schneider CA, Rasband WS, Eliceiri KW. NIH Image to ImageJ: 25 years of image analysis. Nat Methods 2012; 9(7): 671-5.
  • Schmitt C, Lutz R, Doering H, Lell M, Ratky J, Schlegel KA. Bio-Oss blocks combined with BMP-2 and VEGF for the regeneration of bony defects and vertical augmentation. Clin Oral Implants Res 2013; 24(4): 450-60.
  • Shiozawa Y, Jung Y, Ziegler AM, Pedersen EA, Wang J, Wang Z, Song J, Wang J, Lee CH, Sud S, Pienta KJ, Krebsbach PH, Taichman RS. Erythropoietin couples hematopoiesis with bone formation. PLoS ONE 2010;5(5):e10853.
  • Stockmann P, Park J, Wilmowsky von C, Nkenke E, Felszeghy E, Dehner J-F, Schmitt C, Tudor C, Schlegel KA. Guided bone regeneration in pig calvarial bone defects using autologous mesenchymal stem/progenitor cells - a comparison of different tissue sources. J Craniomaxillofac Surg 2012; 40(4): 310-20.
  • Sun H, Jung Y, Shiozawa Y, Taichman RS, Krebsbach PH. Erythropoietin modulates the structure of bone morphogenetic protein 2-engineered cranial bone. Tissue Eng Part A 2012; 18(19-20): 2095-105.
  • Wen D, Boissel JP, Tracy TE, Gruninger RH, Mulcahy LS, Czelusniak J, Goodman M, Bunn HF. Erythropoietin structure-function relationships: high degree of sequence homology among mammals. Blood 1993; 82(5): 1507-16.
  • Wiltfang J, Merten H, Schlegel K, Schultze-Mosgau S, Kloss F, Rupprecht S, Kessler P. Degradation characteristics of alpha and beta tri-calcium- phosphate (TCP) in Minipigs. J Biomed Mater Res 2002; 63(2): 115-21.