References
- Bensimon G, Lacomblez L, Meininger V. A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group. N Engl J Med. 1994;330:585–91.
- Clement AM, Nguyen MD, Roberts EA, Garcia ML, Boillée S, Rule M, . Wild-type non-neuronal cells extend survival of SOD1 mutant motor neurons in ALS mice. Science. 2003;302:113–7.
- Miller TM, Cleveland DW. Has gene therapy for ALS arrived? Nat Med. 2003;9:1256–7.
- Di Giorgio FP, Carrasco MA, Siao MC, Maniatis T, Eggan K. Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model. Nat Neurosci. 2007;10:608–14.
- Nagai M, Re DB, Nagata T, Chalazonitis A, Jessell TM, Wichterle H, Przedborski S. Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons. Nat Neurosci. 2007;10:615–22.
- Hedlund E, Hefferan MP, Marsala M, Isacson O. Cell therapy and stem cells in animal models of motor neuron disorders. Eur J Neurosci. 2007;26:1721–37.
- Ende N, Weinstein F, Chen R, Ende M. Human umbilical cord blood effect on SOD mice (amyotrophic lateral sclerosis). Life Sci. 2000;67:53–9.
- Garbuzova-Davis S, Sanberg CD, Kuzmin-Nichols N, Willing AE, Gemma C, Bickford PC, . Human umbilical cord blood treatment in a mouse model of ALS: optimization of cell dose. PLoS ONE. 2008;3:2494.
- Habisch HJ, Janowski M, Binder D, Kuzma-Kozakiewicz M, Widmann A, Habich A, . Intrathecal application of neuroectodermally converted stem cells into a mouse model of ALS: limited intraparenchymal migration and survival narrows therapeutic effects. J Neural Transm. 2007;114: 1395–1406.
- Mazzini L, Fagioli F, Boccaletti R, Mareschi K, Oliveri G, Olivieri C, . Stem cell therapy in amyotrophic lateral sclerosis: a methodological approach in humans. Amyotroph Lateral Scler Other Motor Neuron Disord. 2003;4:158–61.
- Mazzini L, Mareschi K, Ferrero I, Vassallo E, Oliveri G, Nasuelli N, . Stem cell treatment in amyotrophic lateral sclerosis. J Neurol Sci. 2008;265:78–83.
- Mazzini L, Ferrero I, Luparello V, Rustichelli D, Gunetti M, Mareschi K, . Mesenchymal stem cell transplantation in amyotrophic lateral sclerosis: a phase I clinical trial. Exp Neurol. 2010;223:229–37.
- Belzil VV, Valdmanis PN, Dion PA, Daoud H, Kabashi E, Noreau A, . Mutations in FUS cause FALS and SALS in French and French-Canadian populations. Neurology. 2009;73:1176–9.
- Dion PA, Daoud H, Rouleau GA. Genetics of motor neuron disorders: new insights into pathogenic mechanisms. Nat Rev Genet. 2009;10:769–82.
- Kabashi E, Valdmanis PN, Dion P, Spiegelman D, McConkey BJ, van de Velde C, . TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis. Nat Genet. 2008;40:572–4.
- Mougeot JL, Richardson-Milazi S, Brooks BR. Whole-genome association studies of sporadic amyotrophic lateral sclerosis: are retroelements involved? Trends Mol Med. 2009;15:148–58.
- Mazzini L, Vercelli A, Mareschi K, Ferrero I, Testa L, Fagioli F. Mesenchymal stem cells for ALS patients. Amyotroph Lateral Scler. 2009;10:123–4.
- Vercelli A, Mereuta OM, Garbossa D, Muraca G, Mareschi K, Rustichelli D, . Human mesenchymal stem cell transplantation extends survival, improves motor performance and decreases neuroinflammation in mouse model of amyotrophic lateral sclerosis. Neurobiol Dis. 2008;31:395–405.
- Nayak MS, Kim YS, Goldman M, Keirstead HS, Kerr DA. Cellular therapies in motor neuron diseases. Biochim Biophys Acta. 2006;1762:1128–38.
- Knippenberg S, Hass R, Dengler R, Petri S. Intraspinal transplantation of adult stem cells improves motor function and survival in G93A-ALS transgenic mouse model. Amyotroph Lateral Scler. 2009;10(Suppl 1):80.
- Chen CT, Foo NH, Liu WS, Chen SH. Infusion of human umbilical cord blood cells ameliorates hind limb dysfunction in experimental spinal cord injury through anti-inflammatory, vasculogenic and neurotrophic mechanisms. Pediatr Neonatol. 2008;49:77–83.
- Garbuzova-Davis S, Willing AE, Zigova T, Saporta S, Justen EB, Lane JC, . Intravenous administration of human umbilical cord-blood cells in a mouse model of amyotrophic lateral sclerosis: distribution, migration, and differentiation. J Hematother Stem Cell Res. 2003;12:255–70.