85
Views
6
CrossRef citations to date
0
Altmetric
Case Reports

Partial motor restoration upon administration of sildenafil: a case study

, MD
Pages 39-43 | Received 06 Oct 2011, Accepted 11 Oct 2011, Published online: 18 Jan 2012

References

  • Kloner RA, Comstock G, Levine LA, Tiger S, Stecher VJ. Investigational non-cardiovascular uses of phosphodiesterase-5 inhibitors. Expert Opinion in Pharmacotherapy 2011; 12: 2297–2313
  • Cayre M, Canoll P, Goldman JE. Cell migration in the normal and pathological postnatal mammalian brain. Progress in Neurobiology 2009; 88: 41–63
  • Pathania M, Yan LD, Bordey A. A symphony of signals conducts early and late stages of adult neurogenesis. Neuropharmacology 2010; 58: 865–876
  • Massouh M, Saghatelyan A. De-routing neuronal precursors in the adult brain to sites of injury: Role of the vasculature. Neuropharmacology 2010; 58: 877–883
  • Carmichael ST. Themes and strategies for studying the biology of stroke recovery in the poststroke epoch. Stroke 2008; 39: 1380–1388
  • Navaratna D, Guo S, Arai K, Lo EH. Mechanisms and targets for angiogenic therapy after stroke. Cell Adhesion & Migration 2009; 3: 216–223
  • Zhang R, Wang Y, Zhang L, Zhang Z, Tsang W, Lu M, Chopp M. Sildenafil (Viagra) induces neurogenesis and promotes functional recovery after stroke in rats. Stroke 2002; 33: 2675–2680
  • Zhang RL, Zhang Z, Zhang L, Wang Y, Zhang C, Chopp M. Delayed treatment with sildenafil enhances neurogenesis and improves functional recovery in aged rats after focal cerebral ischemia. Journal of Neuroscience Research 2006; 83: 1213–1219
  • Zhang L, Zhang RL, Wang Y, Zhang C, Zhang ZG, Meng H, Chopp M. Functional recovery in aged and young rats after embolic stroke: Treatment with a phosphodiesterase type 5 inhibitor. Stroke 2005; 36: 847–852
  • Schmidt NO, Koeder D, Messing M, Mueller FJ, Aboody KS, Kim SU, Black PM, Carroll RS, Westphal M, Lamszus K. Vascular endothelial growth factor-stimulated cerebral microvascular endothelial cells mediate the recruitment of neural stem cells to the neurovascular niche. Brain Research 2009; 1268: 24–37
  • Ii M, Nishimura H, Sekiguchi H, Kamei N, Yokoyama A, Horii M, Asahara T. Concurrent vasculogenesis and neurogenesis from adult neural stem cells. Circulation Research 2009; 105: 860–868
  • Zhang ZG, Chopp M. Neurorestorative therapies for stroke: Underlying mechanisms and translation to the clinic. Lancet Neurology 2009; 8: 491–500
  • Bender AT, Beavo JA. Cyclic nucleotide phosphodiesterases: Molecular regulation to clinical use. Pharmacological Reviews 2006; 58: 488–520
  • Phillips BG, Kato M, Pesek CA, Winnicki M, Narkiewicz K, Davison D, Somers VK. Sympathetic activation by sildenafil. Circulation 2000; 102: 3068–3073
  • Farooq MU, Naravetla B, Moore PW, Majid A, Gupta R, Kassab MY. Role of sildenafil in neurological disorders. Clinical Neuropharmacology 2008; 31: 353–362
  • Bednar MM. The role of sildenafil in the treatment of stroke. Current Opinion in Investigational Drugs 2008; 9: 754–759

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.