Effect of size on biological properties of nanoparticles employed in gene delivery

References

• Avgoustakis K, Beletsi A, Panagi Z, Klepetsanis P, Livaniou E, Evangelatos G, Ithakissios DS. 2003. Effect of copolymer composition on the physicochemical characteristics, in vitro stability, and biodistribution of PLGA-mPEG nanoparticles. Int J Pharm. 259:115–127.
   PubMed Web of Science ®Google Scholar
• Beletsi A, Panagi Z, Avgoustakis K. 2005. Biodistribution properties of nanoparticles based on mixtures of PLGA with PLGA-PEG diblock copolymers. Int J Pharm. 298:233–241.
   PubMed Web of Science ®Google Scholar
• Cebrián V, Martín-Saavedra F, Yagüe C, Arruebo M, Santamaría J, Vilaboa N. 2011. Size-dependent transfection efficiency of PEI-coated gold nanoparticles. Acta Biomater. 7:3645–3655.
   PubMed Web of Science ®Google Scholar
• Cherng JY, van de Wetering P, Talsma H, Crommelin DJ, Hennink WE. 1996. Effect of size and serum proteins on transfection efficiency of poly ((2-dimethylamino)ethyl methacrylate)-plasmid nanoparticles. Pharm Res. 13:1038–42.
   PubMed Web of Science ®Google Scholar
• Chithrani BD, Chan WC. 2007. Elucidating the mechanism of cellular uptake and removal of protein-coated gold nanoparticles of different sizes and shapes. Nano Lett. 7:1542–1550.
   PubMed Web of Science ®Google Scholar
• Chithrani BD, Ghazani AA, Chan WC. 2006. Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells. Nano Lett. 6:662–8.
   PubMed Web of Science ®Google Scholar
• Chowdhury EH, Kunou M, Nagaoka M, Kundu AK, Hoshiba T, Akaike T. 2004. High-efficiency gene delivery for expression in mammalian cells by nanoprecipitates of Ca–Mg phosphate. Gene. 341:77–82.
   PubMed Web of Science ®Google Scholar
• Conner SD, Schmid SL. 2003. Regulated portals of entry into the cell. Nature. 422:37–44.
   PubMed Web of Science ®Google Scholar
• De Jong WH, Hagens WI, Krystek P, Burger MC, Sips AJ, Geertsma RE. 2008. Particle size-dependent organ distribution of gold nanoparticles after intravenous administration. Biomaterials. 29:1912–1919.
   PubMed Web of Science ®Google Scholar
• Deng ZJ, Liang M, Monteiro M, Toth I, Minchin RF. 2011. Nanoparticle-induced unfolding of fibrinogen promotes Mac-1 receptor activation and inflammation. Nat Nanotechnol. 6:39–44.
   PubMed Web of Science ®Google Scholar
• Fang C, Shi B, Pei YY, Hong MH, Wu J, Chen HZ. 2006. In vivo tumor targeting of tumor necrosis factor-alpha-loaded stealth nanoparticles: effect of MePEG molecular weight and particle size. Eur J Pharm Sci. 27:27–36.
   PubMed Web of Science ®Google Scholar
• Foged C, Brodin B, Frokjaer S, Sundblad A. 2005. Particle size and surface charge affect particle uptake by human dendritic cells in an in vitro model. Int J Pharm. 298:315–322.
   PubMed Web of Science ®Google Scholar
• Forrest ML, Meister GE, Koerber JT, Pack DW. 2004. Partial acetylation of polyethylenimine enhances in vitro gene delivery. Pharm Res. 21:365–371.
   PubMed Web of Science ®Google Scholar
• Gratton SE, Ropp PA, Pohlhaus PD, Luft JC, Madden VJ, Napier ME, Desimone JM. 2008. The effect of particle design on cellular internalization pathways. Proc Natl Acad Sci U S A. 105:11613–11618.
   PubMed Web of Science ®Google Scholar
• Gregoriadis G (Ed.) 1988. Liposomes as Drug Carriers: Recent Trends and Progress New York: Wiley.
   Google Scholar
• He C, Hu Y, Yin L, Tang C, Yin C. 2010. Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles. Biomaterials. 31:3657–3666.
   PubMed Web of Science ®Google Scholar
• Huang HC, Barua S, Kay DB, Rege K. 2009. Simultaneous enhancement of photothermal stability and gene delivery efficacy of gold nanorods using polyelectrolytes. ACS Nano. 3:2941–2952.
   PubMed Web of Science ®Google Scholar
• Jiang W, Kimbetty YS, Rutka JT, Chanwarren CW. 2008. Nanoparticle-mediated cellular response is size-dependent. Nat Nano. 3:145–150.
   PubMed Web of Science ®Google Scholar
• Jones NA, Hill IRC, Stolnik S, Bignotti F, Davis SS, Garnett MC. 2000. Polymer chemical structure is a key determinant of physicochemical and colloidal properties of polymer–DNA complexes for gene delivery. Biochim Biophys Acta. 1517:1–18.
   PubMed Web of Science ®Google Scholar
• Junghans M, Kreuter J, Zimmer A. 2000. Antisense delivery using protamine-oligonucleotide particles. Nucleic Acids Res. 28:E45.
   PubMedGoogle Scholar
• Kichler A, Mason AJ, Bechinger B. 2006. Cationic amphipathic histidine-rich peptides for gene delivery. Biochim Biophys Acta. 1758:301–307.
   PubMed Web of Science ®Google Scholar
• Lai SK, Hida K, Chen C, Hanes J. 2008. Characterization of the intracellular dynamics of a non-degradative pathway accessed by polymer nanoparticles. J Control Release. 125:107–111.
   PubMed Web of Science ®Google Scholar
• Lai SK, Hida K, Man ST, Chen C, Machamer C, Schroer TA, Hanes J. 2007. Privileged delivery of polymer nanoparticles to the perinuclear region of live cells via a non-clathrin, non-degradative pathway. Biomaterials. 28:2876–2884.
   PubMed Web of Science ®Google Scholar
• Lee H, Fonge H, Hoang B, Reilly RM, Allen C. 2010. The effects of particle size and molecular targeting on the intratumoral and subcellular distribution of polymeric nanoparticles. Mol Pharm. 7:1195–1208.
   PubMed Web of Science ®Google Scholar
• Lochmann D, Weyermann J, Georgens C, Prassl R, Zimmer A. 2005. Albumin-protamine-oligonucleotide nanoparticles as a new antisense delivery system. Part. 1:physicochemical characterization. Eur J Pharm Biopharm. 59:419–429.
   PubMed Web of Science ®Google Scholar
• Mayer G, Vogel V, Weyermann J, Lochmann D, van den Broek JA, Tziatzios C, et al. 2005. Oligonucleotide-protamine-albumin nanoparticles: protamine sulfate causes drastic size reduction. J Control Release. 106:181–187.
   PubMed Web of Science ®Google Scholar
• Mayor S, Pagano RE. 2007. Pathways of clathrin-independent endocytosis. Nat Rev Mol Cell Biol. 8:603–612.
   PubMed Web of Science ®Google Scholar
• Mislick KA, Baldeschwieler JD. 1996. Evidence for the role of proteoglycans in cation-mediated gene transfer. Proc Natl Acad Sci U S A. 93:12349–12354.
   PubMed Web of Science ®Google Scholar
• Mosqueira VC, Legrand P, Morgat JL, Vert M, Mysiakine E, Gref R, et al. 2001. Biodistribution of long-circulating PEG-grafted nanocapsules in mice: effects of PEG chain length and density. Pharm Res. 18:1411–1419.
   PubMed Web of Science ®Google Scholar
• Muller RH (Ed.) 1991. Colloidal Carriers for Controlled Drug Delivery and Targeting. Boca Raton: CRC press.
   Google Scholar
• Niidome T, Nakashima K, Takahashi H, Niidome Y. 2004. Preparation of primary amine-modified gold nanoparticles and their transfection ability into cultivated cells. Chem Commun. (17): 1978–1979.
   PubMedGoogle Scholar
• Nimesh S, Gupta N, Chandra R. 2011. Cationic polymer based nanocarriers for delivery of therapeutic nucleic acids. J Biomed Nanotechnol. 7:504–520.
   PubMed Web of Science ®Google Scholar
• Ogris M, Brunner S, Schuller S, Kircheis R, Wagner E. 1999. PEGylated DNA/transferrin-PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery. Gene Ther. 6:595–605.
   PubMed Web of Science ®Google Scholar
• Ogris M, Steinlein P, Carotta S, Brunner S, Wagner E. 2001. DNA/polyethylenimine transfection particles: influence of ligands, polymer size, and PEGylation on internalization and gene expression. AAPS PharmSci. 3:E21.
   PubMed Web of Science ®Google Scholar
• Ogris M, Steinlein P, Kursa M, Mechtler K, Kircheis R, Wagner E. 1998. The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells. Gene Ther. 5: 1425–1433.
   PubMed Web of Science ®Google Scholar
• Pan Y, Neuss S, Leifert A, Fischler M, Wen F, Simon U, et al. 2007. Size-dependent cytotoxicity of gold nanoparticles. Small. 3: 1941–1949.
   PubMed Web of Science ®Google Scholar
• Pante N, Aebi U. 1996. Molecular dissection of the nuclear pore complex. Crit Rev Biochem Mol Biol. 31:153–199.
   PubMed Web of Science ®Google Scholar
• Panyam J, Labhasetwar V. 2003. Biodegradable nanoparticles for drug and gene delivery to cells and tissue. Adv Drug Deliv Rev. 55: 329–347.
   PubMed Web of Science ®Google Scholar
• Peng SF, Yang MJ, Su CJ, Chen HL, Lee PW, Wei MC, Sung HW. 2009. Effects of incorporation of poly(gamma-glutamic acid) in chitosan/DNA complex nanoparticles on cellular uptake and transfection efficiency. Biomaterials. 30:1797–1808.
   PubMed Web of Science ®Google Scholar
• Prabha S, Zhou WZ, Panyam J, Labhasetwar V. 2002. Size-dependency of nanoparticle-mediated gene transfection: studies with fractionated nanoparticles. Int J Pharm. 244:105–115.
   PubMed Web of Science ®Google Scholar
• Rejman J, Oberle V, Zuhorn IS, Hoekstra D. 2004. Size-dependent internalization of particles via the pathways of clathrin- and caveolae-mediated endocytosis. Biochem J. 377:159–169.
   PubMed Web of Science ®Google Scholar
• Sandhu KK, Mcintosh CM, Simard JM, Smith SW, Rotello VM. 2002. Gold nanoparticle-mediated transfection of mammalian cells. Bioconjug Chem. 13:3–6.
   PubMed Web of Science ®Google Scholar
• Shenoy DB, Amiji MM. 2005. Poly(ethylene oxide)-modified poly(epsilon-caprolactone) nanoparticles for targeted delivery of tamoxifen in breast cancer. Int J Pharm. 293:261–270.
   PubMed Web of Science ®Google Scholar
• Shu XZ, Zhu KJ. 2000. A novel approach to prepare tripolyphosphate/chitosan complex beads for controlled release drug delivery. Int J Pharm. 201:51–58.
   PubMed Web of Science ®Google Scholar
• Song C, Labhasetwar V, Cui X, Underwood T, Levy RJ. 1998. Arterial uptake of biodegradable nanoparticles for intravascular local drug delivery: results with an acute dog model. J Control Release. 54: 201–211.
   PubMed Web of Science ®Google Scholar
• Stolnik S, Heald CR, Neal J, Garnett MC, Davis SS, Illum L, et al. 2001. Polylactide-poly(ethylene glycol) micellar-like particles as potential drug carriers: production, colloidal properties and biological performance. J Drug Target. 9:361–378.
   PubMed Web of Science ®Google Scholar
• Thomas M, Klibanov AM. 2003. Conjugation to gold nanoparticles enhances polyethylenimine's transfer of plasmid DNA into mammalian cells. Proc Natl Acad Sci U S A. 100:9138–9143.
   PubMed Web of Science ®Google Scholar
• Wagner E, Cotten M, Foisner R, Birnstiel ML. 1991. Transferrin- polycation-DNA complexes: the effect of polycations on the structure of the complex and DNA delivery to cells. Proc Natl Acad Sci U S A. 88:4255–4259.
   PubMed Web of Science ®Google Scholar
• Wang DA, Narang AS, Kotb M, Gaber AO, Miller DD, Kim SW, Mahato RI. 2002. Novel branched poly(ethylenimine)-cholesterol water-soluble lipopolymers for gene delivery. Biomacromolecules. 3:1197–1207.
   PubMed Web of Science ®Google Scholar
• Weyermann J, Lochmann D, Georgens C, Zimmer A. 2005. Albumin-protamine-oligonucleotide-nanoparticles as a new antisense delivery system. Part. 2:cellular uptake and effect. Eur J Pharm Biopharm. 59:431–438.
   PubMed Web of Science ®Google Scholar
• Xiong S, George S, Yu H, Damoiseaux R, France B, Ng KW, Loo JS. 2013. Size influences the cytotoxicity of poly (lactic-co-glycolic acid) (PLGA) and titanium dioxide (TiO(2)) nanoparticles. Arch Toxicol. 87:1075–1086.
   PubMed Web of Science ®Google Scholar
• Yanagishita M, Hascall VC. 1992. Cell surface heparan sulfate proteoglycans. J Biol Chem. 267:9451–9454.
   PubMed Web of Science ®Google Scholar
• Zhang G, Yang Z, Lu W, Zhang R, Huang Q, Tian M, et al. 2009. Influence of anchoring ligands and particle size on the colloidal stability and in vivo biodistribution of polyethylene glycol-coated gold nanoparticles in tumor-xenografted mice. Biomaterials. 30:1928–1936.
   PubMed Web of Science ®Google Scholar