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ORIGINAL ARTICLE

A Comparison between the cytotoxic effects of pure curcumin and curcumin-loaded PLGA-PEG nanoparticles on the MCF-7 human breast cancer cell line

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Pages 423-430 | Received 02 Aug 2014, Accepted 12 Aug 2014, Published online: 17 Sep 2014

References

  • Abbasi E, Aval SF, Akbarzadeh A, Milani M, Nasrabadi HT, Joo SW, Hanifehpour Y, Nejati-Koshki K, et al. 2014a. Dendrimers: synthesis, applications and properties. Nanoscale Res Lett. 9:247.
  • Abbasi E, Milani M, Aval SF, Kouhi M, Akbarzadeh A, Nasrabadi HT, et al. 2014b. Silver nanoparticles: synthesis, properties, bio- applications and limitations. Crit Rev Microbiol. 1–8.
  • Ahmadi A, Shirazi H, Pourbagher N, Akbarzadeh A, Omidfar K. 2014. An electrochemical immunosensor for digoxin using core-shell gold coated magnetic nanoparticles as labels. Mol Biol Rep. 41: 1659–1668.
  • Akbarzadeh A, Mikaeili H, Zarghami N, Mohammad R, Barkhordari A, Davaran S. 2012a. Preparation and in-vitro evaluation of doxorubicin-loaded Fe3O4 magnetic nanoparticles modified with biocompatible copolymers. Int J Nanomedicine. 7:511–526.
  • Akbarzadeh A, Nejati-Koshki K, Soghrati MM, Alimohammadi S, Ghamari MF, Davaran S. 2013a. In vitro studies of NIPAAM-MAA-VP copolymer-coated magnetic nanoparticles for controlled anticancer drug release. J Encapsulation Adsorpt Sci. 3:108–115.
  • Akbarzadeh A, Rezaei A, Nejati-Koshki K, Alimohammadi S, Davaran S. 2014. Synthesis and physicochemical characterization of biodegradable star-shaped poly lactide-co-glycolide–β-cyclodextrin copolymer nanoparticles containing albumin. Adv Nanoparticles. 3:14–22.
  • Akbarzadeh A, Rezaei-Sadabady R, Davaran S, Joo SW, Zarghami N, Hanifehpour Y, et al. 2013b. Liposome: classification, preparation, and applications. Nanoscale Res Lett. 8:102.
  • Akbarzadeh A, Samiei M, Davaran S. 2012b. Magnetic nanoparticles: preparation, physical properties and applications in biomedicine. Nanoscale Res Lett. 7:144–157.
  • Akbarzadeh A, Zarghami N, Mikaeili H, Asgari D, Goganian AM, Khiabani HK, Davaran S. 2012d. Synthesis, characterization and in vitro evaluation of novel polymer-coated magnetic nanoparticles for controlled delivery of doxorubicin. Int J Nanotechnol Sci Environ. 5:13–25.
  • Akbarzadeh A, Samiei M, Joo SW, Anzaby M, Hanifehpour Y, Nasrabadi HT, Davaran S. 2012c. Synthesis, characterization and in vitro studies of doxorubicin-loaded magnetic nanoparticles grafted to smart copolymers on A549 lung cancer cell line. J Nanobiotechnol. 10:46.
  • Alimirzalu S, Akbarzadeh A, Abbasian M, Alimohammadi S, Davaran S, Hanifehpour Y, et al. 2014. Synthesis and study of physicochemical characteristics of Fe3O4 magnetic nanocomposites based on poly(Nisopropylacrylamide)for anti-cancer drugs delivery. Asian Pac J Cancer Prev. 15:49–54.
  • Alizadeh E, Zarghami N, Baghaban Eslaminejad MR, Akbarzadeh A, Jahangir S, Barzegar A, et al. 2014. The effect of dimethyl sulfoxide on hepatogenic differentiation of mesenchymal stem cells. Int J Pediatr. (2):57–58.
  • Anand P, Nair HB, Sung B, Kunnumakkara AB, Yadav VR, Tekmal RR, Aggarwal BB. 2010. Design of curcumin-loaded PLGA nanoparticles formulation with enhanced cellular uptake, and increased bioactivity in vitro and superior bioavailability in vivo. Biochem Pharmacol. 79:330–338.
  • Anand P, Sundaram C, Jhurani S, Kunnumakkara AB, Aggarwal BB. 2008. Curcumin and cancer: an “old-age” disease with an “age-old” solution. Cancer lett. 267:133–164.
  • Anganeh MT, Sadat Tabatabaei Mirakabad F, Izadi M, Zeighamian V, Badrzadeh F, Salehi R, et al. 2014. The comparison between effects of free curcumin and curcumin loaded PLGA-PEG on telomerase and TRF1 expressions in calu-6 lung cancer cell line. Int J Biosci. 4:134–145.
  • Danhier F, Ansorena E, Silva JM, Coco R, Le Breton A, Préat V. 2012. PLGA-based nanoparticles: an overview of biomedical applications. J Control Release. 161:505–522.
  • Davoudi Z, Akbarzadeh A, Rahmatiyamchi M, Movassaghpour AA, Alipour M, Nejati-Koshki K, et al. 2014. Molecular target therapy of Akt and NF-kB signaling pathways and multidrug resistanceby specific cell penetrating inhibitor peptides in HL-60 cell line. Asian Pac J Cancer Prev. 9:4353–4358.
  • Dinarvand R, Sepehri N, Manoochehri S, Rouhani H, Atyabi F. 2011. Polylactide-co-glycolide nanoparticles for controlled delivery of anticancer agents. Int J Nanomedicine. 6:877–895.
  • Eatemadi A, Daraee H, Zarghami N, Melat Yar H, Akbarzadeh A, Hanifehpour Y. 2014. Nanofiber: synthesis and biomedical applications. Artif Cells Nanomed Biotechnol. 1–11.
  • Ebrahimnezhad Z, Zarghami N, Keyhani M, Amirsaadat S, Akbarzadeh A, Rahmati M. 2013. Inhibition of hTERT gene expression by silibinin-loaded PLGA-PEG-Fe3O4 in T47D breast cancer cell line. BioImpacts. 3:67–74.
  • Ghasemali S, Nejati-Koshki K, Tafsiri E, Rahmati-Yamchi M, Akbarzadeh A, Alizadeh E, et al. 2013. Study of inhibitory effect of β-cyclodextrin-helenalin complex on HTERT gene expression in T47D breast cancer cell line by real time quantitative PCR (q-PCR). Asian Pac J Cancer Prev. 14:6949–6953.
  • Hosseininasab S, Pashaei-Asl R, Khandaghi AA, Nasrabadi HT, Nejati-Koshki K, Akbarzadeh A, et al. 2014. Synthesis, characterization, and In vitro studies of PLGA-PEG nanoparticles for oral Insulin delivery. Chem Biol Drug Design. 84:307–315.
  • Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. 2011. Global cancer statistics. CA Cancer J Clin. 61:69–90.
  • Kouhi M, Vahedi A, Akbarzadeh A, Hanifehpour Y, Joo SW. 2014. Investigation of quadratic electro-optic effects and electro absorption process in GaN/AlGaN spherical auantum dot. Nanoscale Res Lett. 9:1–6.
  • Liu J, Chen S, Lv L, Song L, Guo S, Huang S. 2013. Recent progress in studying curcumin and its nano-preparations for cancer therapy. Curr Pharm Des. 19:1974–1993.
  • Mahapatro A, Singh DK. 2011. Biodegradable nanoparticles are excellent vehicle for site directed in-vivo delivery of drugs and vaccines. J Nanobiotechnology. 9:55.
  • McPherson K, Steel C, Dixon J. 2000. ABC of breast diseases: breast cancer—epidemiology, risk factors, and genetics. BMJ. 321:624.
  • Mollazade M, Nejati-Koshki K, Akbarzadeh A, Zarghami N, Nasiri M, Jahanban-Esfahlan R, Alibakhshi A. 2013. PAMAM dendrimers arugment inhibitory effect of curcumin on cancer cell proliferation: possible inhibition of telomerase. Asian Pac J Cancer Prev. 14:6925–6928.
  • Nejati-Koshki K, Akbarzadeh A, Pourhasan-Moghadam M, Joo SW. 2013. Inhibition of leptin and leptin receptor gene expression by silibinin- curcumin combination. APJCP. 14:6595.
  • Pourhassan-Moghaddam M, Rahmati-Yamchi M, Akbarzadeh A, Daraee H, Nejati-Koshki K, Hanifehpour Y, Joo SW. 2013. Protein detection through different platforms of immuno-loop-mediated isothermal amplification. Nanoscale Res Lett. 8:485.
  • Pourhassan-Moghaddam M, Zarghami N, Mohsenifar A, Rahmati-Yamchi M, Gholizadeh D, Akbarzadeh A, et al. 2014. Watercress-based gold nanoparticles: biosynthesis, mechanism of formation and study of their biocompatibility in vitro. Micro Nano Lett. 9:345–350.
  • Rasul A, Parveen S, Ma T. 2012. Costunolide: A novel anti-cancer sesquiterpene lactone. Bangladesh J Pharmacol. 7: 6–13.
  • Rezaei-Sadabady R, Zarghami N, Barzegar A, Eidi A, Akbarzadeh A, Rezaei-Tavirani M. 2013. Studies of the relationship between structure and antioxidant activity in interesting systems, including tyrosol, hydroxytyrosol derivatives indicated by quantum chemical calculations. Soft. 2:13–18.
  • Sadat Tabatabaei Mirakabad F, Akbarzadeh A, Zarghami N, Zeighamian V, Rahimzadeh A, Alimohammadi S. 2014a. PLGA-cased nanoparticles as cancer drug delivery systems. Asian Pac J Cancer Prev. 15:517–535.
  • Sadat Tabatabaei Mirakabad F, Nejati-Koshki K, Akbarzadeh A, Yamchi MR, Milani M, Zarghami N, et al. 2014b. PLGA-based nanoparticles as cancer drug delivery systems. Asian Pac J Cancer Prev. 15: 517–535.
  • Sadeghi-Aliabadi H, Ahmadi A. 2000. Cytotoxicity and antitumor properties of a marine compound on cancer cells (HESA-A). Med J Islam Acad Sci. 13:55–61.
  • Shaikh J, Ankola DD, Beniwal V, Singh D, Kumar MN. 2009. Nanoparticle encapsulation improves oral bioavailability of curcumin by at least 9-fold when compared to curcumin administered with piperine as absorption enhancer. Eur J Pharm Sci. 37:223–230.
  • Singh R, Lillard JW Jr. 2009. Nanoparticle-based targeted drug delivery. Exp Mol Pathol. 86:215–223.
  • Valizadeh A, Mikaeili H, Samiei M, Farkhani SM, Zarghami N, Kouhi M, et al. 2012. Quantum dots: synthesis, bioapplications, and toxicity. Nanoscale Res Lett.7:276.
  • Verderio P, Bonetti P, Colombo M, Pandolfi L, Prosperi D. 2013. Intracellular drug release from curcumin-loaded PLGA nanoparticles induces G2/M block in breast cancer cells. Biomacromolecules. 14:672–682.
  • Yallapu MM, Gupta BK, Jaggi M, Chauhan SC. 2010. Fabrication of curcumin encapsulated PLGA nanoparticles for improved therapeutic effects in metastatic cancer cells. J Colloid Interface Sci. 351:19–29.
  • Zhou QM, Wang XF, Liu XJ, Zhang H, Lu YY, Su SB. 2011. Curcumin enhanced antiproliferative effect of mitomycin C in human breast cancer MCF-7 cells in vitro and in vivo. Acta Pharmacol Sin. 32: 1402–1410.

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