2,153
Views
38
CrossRef citations to date
0
Altmetric
ORIGINAL ARTICLE

Development, optimization and evaluation of polymeric electrospun nanofiber: A tool for local delivery of fluconazole for management of vaginal candidiasis

, , &
Pages 524-531 | Received 29 Aug 2014, Accepted 12 Sep 2014, Published online: 15 Oct 2014

References

  • Baumgarten PK. 1971. Electrostatic spinning of acrylic microfibers. J Colloid Interface Sci. 36:71–79.
  • Beigi RH, Meyn LA, Moore DM, Krohn MA, Hillier SL. 2004. Vaginal yeast colonization in nonpregnant women: a longitudinal study. Obstet Gynecol. 104:926–930.
  • Briscoe B, Luckham P, Zhu S. 2000. The effects of hydrogen bonding upon the viscosity of aqueous poly(vinyl alcohol) solutions. Polymer. 41:3851–3860.
  • Buchko CJ, Chen LC, Shen Y, Martin DC. 1999. Processing and microstructural characterization of porous biocompatible protein polymer thin films. Polymer. 40:7397–7407.
  • Cai W, Gupta RB. 2000. Hydrogels. In: Kirk-Othmer Encyclopedia of Chemical Technology. New York: John Wiley & Sons, Inc: 367–410.
  • Chaudhary S, Garg T, Murthy RS, Rath G, Goyal AK. 2014. Recent approaches of lipid-based delivery system for lymphatic targeting via oral route. J Drug Target. 1–12.
  • Deitzel JM, Kleinmeyer J, Harris D, Beck Tan NC 2001. The effect of processing variables on the morphology of electrospun nanofibers and textiles. Polymer. 42:261–272.
  • Dennerstein G. 1998. Pathogenesis and treatment of genital candidiasis. Aust Fam Physician. 27:363–369.
  • Gagandeep Garg T., Malik B, Rath G, Goyal AK. 2014. Development and characterization of nano-fiber patch for the treatment of glaucoma. Eur J Pharm Sci. 53:10–16.
  • Garg T. 2014. Current nanotechnological approaches for an effective delivery of bio-active drug molecules in the treatment of acne. Artif Cells Nanomed Biotechnol. 1–8.
  • Garg T, Goyal AK. 2012. Iontophoresis: Drug delivery system by applying an electrical potential across the skin. Drug Deliv Lett. 2:270–280.
  • Garg T, Goyal AK. 2014a. Biomaterial-based scaffolds–current status and future directions. Expert Opin Drug Deliv. 11:767–789.
  • Garg T, Goyal AK. 2014b. Liposomes: Targeted and controlled delivery system. Drug Deliv Lett. 4:62–71.
  • Garg T, Goyal AK, Arora S, Murthy R. 2012a. Development, optimization & evaluation of porous chitosan scaffold formulation of gliclazide for the treatment of type-2 diabetes mellitus. Drug Deliv Lett. 2:251–261.
  • Garg T, Rath G, Goyal AK. 2014a. Ancient and advanced approaches for the treatment of an inflammatory autoimmune disease-psoriasis. Crit Rev Ther Drug Carrier Syst. 31:331–364.
  • Garg T, Rath G, Goyal AK. 2014b. Comprehensive review on additives of topical dosage forms for drug delivery. Drug Deliv.
  • Garg T, Singh O, Arora S, Murthy R. 2012b. Scaffold: a novel carrier for cell and drug delivery. Crit Rev Ther Drug Carrier Syst. 29:1–63.
  • Garg T, Singh S, Goyal AK. 2013. Stimuli-sensitive hydrogels: an excellent carrier for drug and cell delivery. Crit Rev Ther Drug Carrier Syst. 30:369–409.
  • Glover DD, Larsen B. 2003. Relationship of fungal vaginitis therapy to prior antibiotic exposure. Infect Dis Obstet Gynecol. 11:157–160.
  • Goyal AK, Rath G, Garg T. 2013a. Nanotechnological approaches for genetic immunization. In: Erdmann VA & Barciszewski J, Eds. DNA and RNA Nanobiotechnologies in Medicine: Diagnosis and Treatment of Diseases Berlin: Springer, pp. 67–120.
  • Goyal G, Garg T, Malik B, Chauhan G, Rath G, Goyal AK. 2013b. Development and characterization of niosomal gel for topical delivery of benzoyl peroxide. Drug Deliv.
  • Goyal G, Garg T, Rath G, Goyal AK. 2014. Current nanotechnological strategies for an effective delivery of drugs in treatment of periodontal disease. Crit Rev Ther Drug Carrier Syst. 31:89–119.
  • Heikkilä P, Harlin A. 2008. Parameter study of electrospinning of polyamide-6. Eur Polym J. 44:3067–3079.
  • Homayoni H, Ravandi SAH, Valizadeh M. 2009. Electrospinning of chitosan nanofibers: processing optimization. Carbohydr Polym. 77:656–661.
  • Inagaki K, Takagi J, Lor E, Okamoto MP, Gill MA. 1992. Determination of fluconazole in human serum by solid-phase extraction and reversed-phase high-performance liquid chromatography. Ther Drug Monit. 14:306–311.
  • Johal HS, Garg T, Rath G, Goyal AK. 2014. Advanced topical drug delivery system for the management of vaginal candidiasis. Drug Deliv.1–14.
  • Joshi D, Garg T, Goyal AK, Rath G. 2014. Advanced drug delivery approaches against periodontitis. Drug Deliv. 1–15.
  • Kataria K, Sharma A, Garg T, Goyal AK, Rath G. 2014. Novel technology to improve drug loading in polymeric nanofibers. Drug Deliv Lett. 4:79–86.
  • Kaur M, Garg T, Rath G, Goyal AK. 2014a. Current nanotechnological strategies for effective delivery of bioactive drug molecules in the treatment of tuberculosis. Crit Rev Ther Drug Carrier Syst. 31:49–88.
  • Kaur M, Malik B, Garg T, Rath G, Goyal AK. 2014b. Development and characterization of guar gum nanoparticles for oral immunization against tuberculosis. Drug Deliv.
  • Kaur P, Garg T, Rath G, Murthy RS, Goyal AK. 2014c. Surfactant-based drug delivery systems for treating drug-resistant lung cancer. Drug Deliv. 1–12.
  • Kaur R, Garg T, Das Gupta U., Gupta P, Rath G, Goyal AK. 2014d. Preparation and characterization of spray-dried inhalable powders containing nanoaggregates for pulmonary delivery of anti-tubercular drugs. Artif Cells Nanomed Biotechnol.1–6.
  • Kaur R, Garg T, Malik B, Gupta UD, Gupta P, Rath G, Goyal AK. 2014e. Development and characterization of spray-dried porous nanoaggregates for pulmonary delivery of anti-tubercular drugs. Drug Deliv.1–6.
  • Kwon IK, Kidoaki S, Matsuda T. 2005. Electrospun nano- to microfiber fabrics made of biodegradable copolyesters: structural characteristics, mechanical properties and cell adhesion potential. Biomaterials. 26:3929–3939.
  • Lala NL, Ramaseshan R, Bojun L, Sundarrajan S, Barhate RS, Ying-Jun L, Ramakrishna S. 2007. Fabrication of nanofibers with antimicrobial functionality used as filters: protection against bacterial contaminants. Biotechnol Bioeng. 97:1357–1365.
  • Li W-J, Tuli R, Huang X, Laquerriere P, Tuan RS. 2005. Multilineage differentiation of human mesenchymal stem cells in a three- dimensional nanofibrous scaffold. Biomaterials. 26:5158–5166.
  • Ma Z, Kotaki M, Yong T, He W, Ramakrishna S. 2005. Surface engineering of electrospun polyethylene terephthalate (PET) nanofibers towards development of a new material for blood vessel engineering. Biomaterials. 26:2527–2536.
  • Marwah H, Garg T, Goyal AK, Rath G. 2014. Permeation enhancer strategies in transdermal drug delivery. Drug Deliv. 1–15.
  • Megelski S, Stephens JS, Chase DB, Rabolt JF. 2002. Micro- and nanostructured surface morphology on electrospun polymer fibers. Macromolecules. 35:8456–8466.
  • Modgill V, Garg T, Goyal AK, Rath G. 2014. Permeability study of ciprofloxacin from ultra-thin nanofibrous film through various mucosal membranes. Artif Cells Nanomed Biotechnol. 1–6.
  • Monif GR. 1985. Classification and pathogenesis of vulvovaginal candidiasis. Am J Obstet Gynecol. 152:935–939.
  • Morie A, Garg T, Goyal AK, Rath G. 2014. Nanofibers as novel drug carrier – An overview. Artif Cells Nanomed Biotechnol. 1–9.
  • Ohkawa K, Cha D, Kim H, Nishida A, Yamamoto H. 2004. Electrospinning of chitosan. Macromol Rapid Commun. 25:1600–1605.
  • Parnami N, Garg T, Rath G, Goyal AK. 2013. Development and characterization of nanocarriers for topical treatment of psoriasis by using combination therapy. Artif Cells Nanomed Biotechnol.
  • Ramakrishna S, Fujihara K, Teo WE, Lim TC, Ma Z. 2005. An Introduction to Electrospinning and Nanofibers, vol. 1. New Jersey: World Scientific, pp. 91–101.
  • Reneker DH, Chun I. 1996. Nanometre diameter fibers of polymer, produced by electrospinning. Nanotechnology. 7:216–223.
  • Rohilla R, Garg T, Goyal AK, Rath G. 2014. Herbal and polymeric approaches for liver-targeting drug delivery: novel strategies and their significance. Drug Deliv. 1–17.
  • Saeed K, Haider S, Oh TJ, Park SY. 2008. Preparation of amidoxime-modified polyacrylonitrile (PAN-oxime) nanofibers and their applications to metal ions adsorption. J. Membr Sci. 322:400–405.
  • Sharma R, Singh H, Joshi M, Sharma A, Garg T, Goyal AK, Rath G. 2014. Recent advances in polymeric electrospun nanofibers for drug delivery. Crit Rev Ther Drug Carrier Syst. 31:187–217.
  • Shin YM, Hohman MM, Brenner MP, Rutledge GC. 2001. Experimental characterization of electrospinning: the electrically forced jet and instabilities. Polymer. 42:09955–09967.
  • Singh B, Garg T, Goyal AK, Rath G. 2014a. Recent advancements in the cardiovascular drug carriers. Artif Cells Nanomed Biotechnol.1–10.
  • Singh H, Sharma R, Joshi M, Garg T, Goyal AK, Rath G. 2014b. Transmucosal delivery of Docetaxel by mucoadhesive polymeric nanofibers. Artif Cells Nanomed Biotechnol.
  • Singh O, Garg T, Rath G, Goyal AK. 2014c. Microbicides for the treatment of sexually transmitted HIV infections. J Pharm. 1–18.
  • Sobel JD, Faro S, Force RW, Foxman B, Ledger WJ, Nyirjesy PR, et al. 1998. Vulvovaginal candidiasis: epidemiologic, diagnostic, and therapeutic considerations. Am J Obstet Gynecol. 178:203–211.
  • Taylor GI. 1969. Electrically driven jets. Proc R Soc Lond A. 313: 453–475.
  • Wannatong L, Sirivat A, Supaphol P. 2004. Effects of solvents on electrospun polymeric fibers: preliminary study on polystyrene. Polym Int. 53:1851–1859.
  • Zhang C, Yuan X, Wu L, Han Y, Sheng J. 2005. Study on morphology of electrospun poly(vinyl alcohol) mats. Eur Polym J. 41:423–432.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.