910
Views
6
CrossRef citations to date
0
Altmetric
ORIGINAL ARTICLE

Preparation of magnetite-chitosan/methylcellulose nanospheres by entrapment and adsorption techniques for targeting the anti-cancer drug 5-fluorouracil

, , &
Pages 950-959 | Received 23 Sep 2014, Accepted 06 Jan 2015, Published online: 13 Feb 2015

References

  • Babu VR, Rao KSV, Sairam M, Naidu BV, Hosamani KM, Aminabhavi TM. 2006. pH-sensitive interpenetrating network microgels of sodium alginate-acrylic acid for the controlled release of ibuprofen. J Appl Polym Sci. 99:2671–2678.
  • Bulte JWM, Kraitchman DL. 2004. Iron oxide MR contrast agents for molecular and cellular imaging. NMR Biomed. 17:484–499.
  • Butoescu N, Seemayer CA, Foti M, Jordan O, Doelker E. 2009. Dexamethasone-containing PLGA superparamagnetic microparticles as carriers for the local treatment of arthritis. Biomaterials. 30:1772–1780.
  • Chassary P, Vincent T, Guibal E. 2004. Metal anion sorption on chitosan and derivative materials: a strategy for polymer modification and optimum use. React Funct Polym. 60:137–149.
  • Ciofani G, Riggio C, Raffa V, Menciassi A, Cuschieri A 2009. A bi-modal approach against cancer: magnetic alginate nanoparticles for combined chemotherapy and hyperthermia. Med Hypotheses. 73:80–82.
  • Dorniani D, Bin Husscin MZ, Kura AU, Fakurazi S, Shaari AH, Ahmad Z. 2012. Preparation of Fe3O4 magnetic nanoparticles coated with gallic acid for drug delivery. Int J Nanomed. 7:5745–5756.
  • Gan ZF, Jiang JS, Yang Y, Du B, Qian M, Zhang P. 2008. Immobilization of homing peptide on magnetite nanoparticles and its specificity in vitro. J Biomed Mater Res. 84:10–18.
  • Gu HW, Xu KM, Xu CJ, Xu B. 2006. Biofunctional magnetic nanoparticles for protein separation and pathogen detection. Chem Commun. 12:941–949.
  • Guo SJ, Li D, Zhang LX, Li J, Wang E. 2009. Monodisperse mesoporous superparamagnetic single-crystal magnetite nanoparticles for drug delivery. Biomaterials. 30:1881–1889.
  • Gupta AK, Gupta M. 2005. Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications. Biomaterials. 26:3995–4021.
  • Huang L, Sui W, Wang Y, Jiao Q. 2010. Preparation of chitosan/ chondroitin sulfate complex microcapsules and application in controlled release of 5-fluorouracil. Carbohyd Polym. 80:168–173.
  • Işıklan N. 2006. Controlled release of insecticide carbaryl from sodium alginate, sodium alginate/gelatin and sodium alginate/sodium carboxymethyl cellulose blend beads crosslinked with glutaraldehyde. J Appl Polym Sci. 99:1310–1319.
  • Işıklan N, İnal M, Yiğitoğlu M. 2008. Synthesis and characterization of poly(N-vinyl-2-pyrrolidone) grafted sodium alginate hydrogel beads for the controlled release of indomethacin. J Appl Polym Sci. 110:481–493.
  • İnal M, Yiğitoğlu M, Işıklan N. 2008. Controlled release of indomethacin from crosslinked alginate bead. e-Polymers. 8:177–192.
  • Jing XH, Yang L, Duan XJ, Xie B, Chen W, Li Z, Tan HB. 2008. In vivo MR imaging tracking of magnetic iron oxide nanoparticle labeled, engineered, autologous bone marrow mesenchymal stem cells following inrra-articular injection. Jt Bone Spine. 75:432–438.
  • Kulkarni AR, Soppimath KS, Aminabhavi TM. 1999. Controlled release of diclofenac sodium from sodium alginate beads crosslinked with glutaraldehyde. Pharm Acta Helv. 74:29–36.
  • Kumbar SG, Soppimath KS, Aminabhavi TM. 2003. Synthesis and characterization of polyacrylamide-grafted chitosan hydrogel microspheres for the controlled release of indomethacin. J Appl Polym Sci. 87:1525–1536.
  • Kumbar SG, Aminabhavi TM. 2003. Synthesis and characterization of modified chitosan microspheres: effect of the grafting ratio on the controlled release of nifedipine through microspheres. J Appl Poly Sci. 89:2940–2949.
  • Kuroiwa T, Noguchi Y, Nakajima M, Sato S, Mukataka S, Ichikawa S. 2008. Production of chitosan oligosaccharides using chitosanase immobilized on amylose-coated magnetic nanoparticles. Process Biochem. 43:62–69.
  • Lee E, Lee J, Lee IH, Yu M, Kim H, Chae SY, Jon S. 2008. Conjugated chitosan as a novel platform for oral delivery of paclitaxel. J Med Chem. 51:6442–6449.
  • Li G, Jiang Y, Huang K, Ding P, Chen J 2008. Preparation and properties of magnetic Fe3O4-chitosan nanoparticles. J Alloy Compd. 466:451–456.
  • Loh JW, Yeoh G, Saunders M, Lim LY. 2010. Uptake and cytotoxicity of chitosan nanoparticles in human liver cells. Toxicol Appl Pharm. 249:148–157.
  • Loh JW, Saunders M, Lim LY. 2012. Cytotoxicity of monodispersed chitosan nanoparticles against the Caco-2 cells. Toxicol Appl Pharmacol. 262:273–282.
  • Lu A, Salabas EL, Schuth F. 2007. Magnetic nanoparticles: synthesis, protection, functionalization and application. Angew Chem Int Ed Engl. 46:1222–1244.
  • Mao C, Zhu JJ, Hu YF, Ma QQ, Qiu YZ, Zhu AP, et al. 2004. Surface modification using photocrosslinkable chitosan for improving hemocompatibility. Colloid Surface B. 38:47–53.
  • Mc Gann MJ, Higginbotham CL, Geever LM, Nugent MJ. 2009. The synthesis of novel pH-sensitive poly(vinyl alcohol) composite hydrogels using a freeze/thaw process for biomedical applications. Int J Pharm. 372:154–161.
  • Mody VV, Cox A, Shah S, Singh A, Beving W, Parihar H. 2014. Magnetic nanoparticle drug delivery systems for targeting tumor. Appl Nanosci. 4:385–392.
  • Okon E, Pouliquen D, Okon P, Kovaleva ZV, Stepanova TP, Lavit SG, et al. 1974. Biodegradation of magnetite dextran nanoparticles in the rat: a histologic and biophysical study. Lab Invest. 71: 895–903.
  • Olukman M, Şanlı O, Kondolot Solak E. 2012. Releasse of anticancer drug 5-fluorouracil from different ionically crosslinked alginate beads. J Biomater Nanobiotech. 3:469–479.
  • Peppas NA. 1985. Analysis of Fickian and non-Fickian drug release from polymer. Pharm Acta Helv. 60:110–111.
  • Qi L, Xu Z, Jiang X, Li Y, Wang M. 2005. Cytotoxic activities of chitosan nanoparticles and copper-loaded nanoparticles. Bioorg Med Chem Lett. 15:1397–1399.
  • Ritger PL, Peppas NA. 1987. A simple equation for description of solute release II Fickian and anomalous release from swellable devices. J Control Release. 5:37–42
  • Rokhade AP, Shelke NB, Patil SA, Aminabhavi TM. 2007. Novel interpenetrating polymer network microspheres of chitosan and methylcellulose for controlled release of theophylline. Carbohydr Polym. 69:678–687.
  • Saikia C, Hussain A, Ramteke A, Sharma HK, Maji TK. 2014. Carboxy methyl starch-chitosan-coated iron oxide magnetic nanoparticles for controlled delivery of isoniazid. Artif Cell Nanomed B. 4:1–11.
  • Soppimath KS, Aminabhavi TM. 2002. Water transport and drug release study from cross-linked polyacrylamide grafted guar gum hydrogel microspheres for the controlled release application. Eur J Pharm Biopharm. 53:87–98.
  • Şanlı O, Kondolot Solak E. 2009. Controlled release of Naproxen from Sodium Alginate and Poly(vinyl alcohol)/Sodium Alginate Blend Beads Crosslinked with Glutaraldehyde. J Appl Polym Sci. 112:2057–2065
  • Trapani A, Sitterberg J, Bakowsky U, Kissel T. 2009. The potential of glycol chitosan nanoparticles as carrier for low water soluble drugs. Int J Pharm. 375:97–106.
  • Xu Y, Lin Y, Zhuang L, Lin J, Lv J, Huang Q, Sun J. 2013. Bleomycin loaded magnetite nanoparticles functionalized by polyacrylic acid as a new antitumoral drug delivery system. Biomed Res Int. 2013:462589.
  • Yang J, Park SB, Yoon HG, Huh YM, Haam S. 2006. Preparation of poly ε-caprolactone nanoparticles containing magnetite for magnetic drug carrier. Int J Pharm. 324:185–190.
  • Yao Q, Liu W, Gou XJ, Gou XQ, Yan J, Song Q, et al. 2013. Preparation, characterization and cytotoxicity of various chitosan nanoparticles. J Nanomat. 2013:ID:183871.
  • Zhang Y, Huo M, Zhou J, Yu D, Wu Y. 2009. Potential of amphiphilically modified low molecular weight chitosan as a novel carrier for hydrophobic anticancer drug: Synthesis, characterization, micellization and cytotoxicity evaluation. Carbohyd Polym. 77:231–238.
  • Zinutti C, Kedzierewicz F, Hoffman M, Benoit JP, Maincent P. 1996. Influence of the casting solvent on the physico-chemical properties of 5-fluorouracil-loaded microspheres. Int J Pharm. 133:97–105.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.