2,196
Views
14
CrossRef citations to date
0
Altmetric
ORIGINAL ARTICLE

Formulation, characterization, and evaluation of ligand-conjugated biodegradable quercetin nanoparticles for active targeting

, , &
Pages 960-970 | Received 12 Oct 2014, Accepted 06 Jan 2015, Published online: 27 Mar 2015

References

  • Soppimath KS, Aminabhavi TM, Kulkarni AR, Rudzinski WE. 2001. Biodegradable polymeric nanoparticles as drug delivery devices. J Control Release. 70:1–20.
  • Makadia HK, Siegel SJ. 2011. Poly Lactic-co-Glycolic Acid (PLGA) as biodegradable controlled drug delivery carrier. Polymers (Basel). 3:1377–1397.
  • Muller RH, Petersen RD, Hommoss A, Pardeike J .2007. Nanostructured lipid carriers (NLC) in cosmetic dermal products. Adv Drug Deliv Rev. 59:522–530.
  • Wissing S, Müller R. 2002. The influence of the crystallinity of lipid nanoparticles on their occlusive properties. Int J Pharm. 242:377–379.
  • Schafer-Korting M, Mehnert W, Korting HC. 2007Lipid nanoparticles for improved topical application of drugs for skin diseases. Adv Drug Deliv Rev. 59:427–443.
  • Uner M. 2006. Preparation, characterization and physico-chemical properties of solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC): their benefits as colloidal drug carrier systems. Pharmazie. 61:375–386.
  • Han F, Li S, Yin R, Liu H, Xu L. 2008. Effect of surfactants on the formation and characterization of a new type of colloidal drug delivery system: nanostructured lipid carriers. Colloids Surf A Physicochem Eng Asp. 315:210–216.
  • Lin X, Li X, Zheng L, Yu L, Zhang Q, Liu W. 2007. Preparation and characterization of monocaprate nanostructured lipid carriers. Colloids Surf A Physicochem Eng Asp. 311:106–111.
  • Lee JW, Lu JY, Low PS, Fuchs PL. 2002. Synthesis and evaluation of taxol–folic acid conjugates as targeted antineoplastics (dagger). Bioorg Med Chem. 10:2397–2414.
  • Wang AZ, Gu F, Zhang L, Chan JM, Radovic-Moreno A, Shaikh MR, Farokhzad OC. 2008. Biofunctionalized targeted nanoparticles for therapeutic applications. Expert Opin Biol Ther. 8:1063–1070.
  • Mittal V, Patel SJ, Sheth SK. 2010. Development and characterization of folate targeted nanoparticle drug delivery system. Intern. J Pharma Bio Sci. 1:1–12
  • Stella B, Arpicco S, Peracchia MT, Desmaële D, Hoebeke J, Renoir M. 2000. Design of folic acid-conjugated nanoparticles for drug targeting. J Pharm Sci. 89:1452–1464.
  • Narayanan S, Binulal NS, Mony U, Manzoor K, Nair S, Menon D. 2010. Folate targeted polymeric ‘green’ nanotherapy for cancer. Nanotechnology. 21:285107.
  • Nobs L, Buchegger F, Gurny R, Allemann E. 2004. Poly(lactic acid) nanoparticles labeled with biologically active neutravidin for active targeting. Eur J Pharm Biopharm. 58:483–490.
  • Nukolova NV, Oberoi HS, Cohen SM, Kabanov AV, Bronich TK. 2011. Folate-decorated nanogels for targeted therapy of ovarian cancer. Biomaterials. 32:5417–5426.
  • Lu Y, Ding N, Yang C, Huang L, Liu J, Xiang G. 2012. Preparation and in vitro evaluation of a folate-linked liposomal curcumin Formulation. J Liposome Res. 22:110–119.
  • Zhang L, Zhu W, Yang C, Guo H, Yu A, Ji J. 2012. A novel folate- modified self-microemulsifying drug delivery system of curcumin for colon targeting. Int J Nanomed. 7:151–162.
  • Dosio F, Milla P, Cattel L. 2010. EC-145, a folate-targeted Vinca alkaloid conjugate for the potential treatment of folate receptor-expressing cancers. Curr Opin Investig Drugs. 11:1424–1433.
  • Xia Q, Hao X, Lu Y, Xu W, Wei H, Ma Q, Gu N. 2008. Production of drug-loaded lipid nanoparticles based on phase behaviors of special hot microemulsions. Colloids Surf A: Physicochem Eng Asp. 313–314:27–30
  • Hentschel A, Gramdorf S, Muller RH, Kurz T. 2008. Carotene-loaded nanostructured lipid carriers. J Food Sci. 73:N1–N6.
  • Wu G, Zhou F, Ge L, Liu X, Kong F. 2012. Novel Mannan-PEG- PEModified bioadhesive PLGA nanoparticles for targeted gene delivery. J Nanomater. 2012:1–9.
  • Teeranachaideekul V, Muller RH, Junyaprasert VB. 2007. Encapsulation of ascorbyl palmitate in nanostructured lipid carriers (NLC)–effects of formulation parameters on physicochemical stability. Int J Pharm. 340:198–206.
  • Mehnert W, Mader K. 2001. Solid lipid nanoparticles: production, characterization and applications. Adv Drug Deliv Rev. 47:165–196.
  • Abu-Izza KA, García-Contreras L, Lu DR. 1996. Preparation and evaluation of sustained release AZT-loaded microspheres: optimization of the release characteristics using response surface methodology. J Pharm Sci. 85:144–149.
  • Kassama LS, Shi, J, Mittal GS. 2008. Optimization of supercritical fluid extraction of lycopene from tomato skin with central composite rotatable design model. Sep Purif Technol. 60:278–284.
  • Huang YB, Tsai YH, Yang WC, Chang JS, Wu PC, Takayama K. 2004. Once-daily propranolol extended-release tablet dosage form: formulation design and in vitro/in vivo investigation. Eur J Pharm Biopharm. 58:607–614.
  • Ahn JH, Kim YP, Lee YM, Seo EM, Lee KW, Kim HS. 2008. Optimization of microencapsulation of seed oil by response surface methodology. Food Chem. 107:98–105.
  • Zhang X, Liu J, Qiao H, Liu H, Ni J, Zhang W, Shi Y. 2010. Formulation optimization of dihydroartemisinin nanostructured lipid carrier using response surface methodology. Powder Technol. 197:120–128
  • Liu CH, Wu CT. 2010. Optimization of nanostructured lipid carriers for lutein delivery; Colloids Surf A Physicochem Eng Aspects. 353:149–156
  • Gambhire M, Bhalekar SMR, Gambhire VM. 2011. Simvastatin loaded Solid lipid nanoparticles: Formulation optimization using Box Behnken design, characterization and in vitro evaluation. Current Pharma Res. 1:157–164.
  • Ghasemian E, Vatanara A, Najafabadi AR, Rouini MR, Gilani K, Darabi M. 2013. Preparation, characterization and optimization of sildenafil citrate loaded PLGA nanoparticles by statistical factorial design. DARU J Pharm Sci. 21:68.
  • Chidambaram M, Manavalan R, Kathiresan K. 2011. Nanotherapeutics to overcome conventional cancer chemotherapy limitations. J Pharm Pharm Sci. 14:67–77.
  • Ungaro F, d’Angelo I, Miro A, La Rotonda MI, Quaglia F. 2012. Engineered PLGA nano- and micro-carriers for pulmonary delivery: challenges and promises. J Pharm Pharmacol. 64: 1217–1235.
  • Cooper DL, Harirforoosh S. 2014. Design and optimization of PLGA-Based diclofenac loaded nanoparticles. PLoS ONE. 9:e87326.
  • Yadav KS, Sawant KK. 2010. Modified nanoprecipitation method for preparation of cytarabine-loaded PLGA nanoparticles. AAPS Pharm Sci Tech. 11:1456–1465
  • Ahlin P, Kristl J, Kristl A, Vrecer F. 2002. Investigation of polymeric nanoparticles as carriers of enalaprilat for oral administration. Int J Pharm. 239:113–120.
  • Varshosaz J, Jafarian A, Salehi G, Zolfaghari B. 2013. Comparing different sterol containing solid lipid nanoparticles for targeted delivery of Quercetin in hepatocellular carcinoma. J Liposome Res. 22–28.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.