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Scandinavian Journal of Infectious Diseases Volume 12, 1980 - Issue 1
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Main Article

Effect of Methotrexate on Phagocytosis and Killing of Staphylococcus Aureus by Human Granulocytes

Gudmund Marhaug Department of Pediatrics, University Hospital, and the Institute of Clinical Medicine, University of Tromsø, Tromsø, Norway
,
Dag Bratlid Department of Pediatrics, University Hospital, and the Institute of Clinical Medicine, University of Tromsø, Tromsø, Norway
&
Peter Johan Moe Department of Pediatrics, University Hospital, and the Institute of Clinical Medicine, University of Tromsø, Tromsø, Norway
Pages 61-65 | Published online: 02 Jan 2015

References

  • . Bertino, J. R., Cashmore, A., Fink, N., Calabresi, P & Lefkowitz, E.: The induction of leukocyte and erythrocyte dihydrofolate reductase by methotrexate. Clin Pharmacol Ther 6: 763, 1965.
  • . Bratlid, D. & Moe, P. J.: Pharmacokinetics of high-dose methotrexate treatment in children. Eur J Clin Pharmacol. In press.
  • . Davies, J. E., Whittaker, J. A. & Khurshid, M.: The effect of cytotoxic drugs on neutrophil phagocytosis in vitro and in patients with acute myelogenous leukemia. Br J Haematol 32: 21, 1976.
  • . Moe, P. J. & Seip, M.: High dose methotrexate in acute lymphocytic leukemia in childhood. Acta Paediatr Scand 67: 265, 1978.
  • . Ruutu, T. & Kosunen, T. U.: In vitro effect of anti-inflammatory agents on phagocytosis and bacterial killing by human neutrophil leukocytes. Acta Pharmacol Toxicol 31: 226, 1972.
  • . Solberg, C. O.: Enhanced susceptibility to infections. A new method for evaluation of neutrophil granulocyte functions. Acta Pathol Microbiol Scand [B] 80: 10, 1972.
  • . Strauss, R. R., Benoy, B. P. & Sbarra, A. J.: Effect of phenylbutazone on phagocytosis and intracellular killing by guinea pig polymorphonuclear leukocytes. J Bacteriol 96: 1982, 1968.
  • . Wang, J. J., Freeman, A. I. & Sinks, L. F.: Treatment of acute lymphocytic leukemia by high-dose intravenous methotrexate. Cancer Res 36: 1441, 1976.
  • . Whittaker, J. A., Hughes, H. R. & Khurshid, M.: The effect of cytotoxic and anti-inflammatory drugs on the phagocytosis of neutrophil leukocytes. Br J Haematol 29: 273, 1975.

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