Advanced search
Publication Cover
Scandinavian Journal of Infectious Diseases Volume 17, 1985 - Issue 2
Submit an article Journal homepage
17
Views
3
CrossRef citations to date
0
Altmetric
Main Article

Trimethoprim and Methenamine Hippurate: A New Theoretical Combination for the Treatment of Urinary Tract Infections

Simo Räisänen Research Laboratories of Pharmaceutical Co Oy Star AB, and the Department of Biomedical Sciences, University of Tampere, Tampere, Finland
,
Pauli Ylitalo Research Laboratories of Pharmaceutical Co Oy Star AB, and the Department of Biomedical Sciences, University of Tampere, Tampere, Finland
,
Anja Toponen Research Laboratories of Pharmaceutical Co Oy Star AB, and the Department of Biomedical Sciences, University of Tampere, Tampere, Finland
&
Jaakko Seppänen Research Laboratories of Pharmaceutical Co Oy Star AB, and the Department of Biomedical Sciences, University of Tampere, Tampere, Finland
Pages 211-218 | Published online: 02 Jan 2015

References

  • . Amyes SGB, Emmerson AM, Smith JT. R-factor mediated trimethoprim resistance: result of two three-month clinical surveys. J Clin Pathol 31: 850, 1978.
  • . Baethke R, Golde G, Gahl G. Sulphamethoxazole/trimethoprim: Pharmacokinetic studies in patients with chronic renal failure. Eur J Clin Pharmacol 4: 233, 1972.
  • . Brendel R. Untersuchungen an Ratten zur Verträglichkeit von Hexamethylentetramin. Arzneim Forsch 14: 51, 1964.
  • . Bushby SRM. Trimethoprim and sulphonamides: Laboratory studies. South Afr Med J 44, Suppl. 15: 3, 1970.
  • . Craig WA, Kunin CM. Trimethoprim-sulfamethoxazole-pharmacodynamic effects of urinary pH and impaired renal function. Studies in humans. Ann Intern Med 78: 491, 1973.
  • . Della Porta G, Colnoghi MI, Parmiani G. Non-carcinogenicity of hexamethylenetetramine in mice and rats. Food Cosmet Toxicol 6: 707, 1968.
  • . Della Porta G, Gabral JR, Parmiani G. Studio della tossicita transplacentare e di cancerogenesi in ratti trattati con esametilentetramina. Tumori 56: 325, 1970.
  • . Edmunds PN. Synergy between sulphonamide and trimethoprim in the presence of pus. J Clin Pathol 31: 162, 1978.
  • . Farrar WE. Trimethoprim-sulfamethoxazole. Antimicrobial synergism. Am Fam Physician 10: 112, 1974.
  • . Gandelman AL. Methenamine mandelate: Antimicrobial activity in urine and correlation with formaldehyde levels. J Urol 97: 533, 1967.
  • . Garrod LP, Waterworth PM. Effect of medium composition on the apparent sensitivity of Pseudomonas aeruginosa to gentamicin. J Clin Pathol 22: 534, 1969.
  • . Greenwood D, O'Grady F. Activity and interaction of trimethoprim and sulphamethoxazole against Escherichia coli. J Clin Pathol 29: 162, 1976.
  • . Hamilton-Miller JMT, Brumfitt W. Methenamine and its salts as urinary tract antiseptics. Variables affecting the antibacterial activity of formaldehyde, mandelic acid, and hippuric acid in vitro. Invest Urol 14: 287, 1977.
  • . Jackson J, Stamey TA. The riker method for determining formaldehyde in the presence of methenamine. Invest Urol 9: 124, 1971.
  • . Kasanen A, Mustakallio E, Koskinen EH, Soini V. Methenamine hippurate in the treatment of urinary tract infections. Ann Clin Res 6: 279, 1974.
  • . Lacey RW, Lewis EL, Anderson JD. Further thoughts on sulphonamide-trimethoprim mixtures. J Clin Pathol 27: 512, 1973.
  • . Männistö PT, Lähteenmäki P. Comparison of sulfadiazine-trimethoprim and amoxycillin in the treatment of acute urinary tract infection. Curr Ther Res 23: 562, 1978.
  • . Schwartz DE, Koechlin BA, Weinfeld RE. Spectrofluorimetric method for the determination of trimethoprim in body fluids. Chemotherapy Suppl. 14: 22, 1969.
  • . Seneca H, Peer P. Clinical pharmacology and antibacterial action of methenamine and its salts. Med Times 97: 243, 1969.
  • . Seppänen J, Sulkava T, Vaalasti T, Korhonen H, Räisänen S, Ylitalo P. Combination of trimethoprim and methenamine hippurate in the treatment of acute urinary tract infections. Scand J Infect Dis 15: 201, 1983.
  • . Seppänen J, Ylitalo P, Julkunen R, Räisänen S, Masar S-E. Pharmacokinetics and clinical experiences of the combination sulfadiazine-trimethoprim in the short-term treatment of acute urinary tract infections. Ann Clin Res 12, Suppl. 25: 39, 1980.
  • . Sharpstone P. The renal handling of trimethoprim and sulfamethoxazole in man. Postgrad Med J 45, Suppl. 38, 1969.
  • . Stokes A, Lacey RW. Effect of thymidine inactivity of trimethoprim and sulphamethoxazole. J Clin Pathol 31: 165, 1978.
  • . Tuomisto J, Kasanen A, Renkonen O-V. Sulfadiazine-trimethoprim combination in the treatment of urinary tract infections. Chemotherapy 23: 337, 1977.
  • . Waterworth PM. A misapplication of the sensitivity test mandelamine discs. J Med Lab Technol 19: 163, 1962.
  • . Yodaiken RE. The uncertain consequences of formaldehyde toxicity. JAMA 246: 1677, 1981.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.