CD154 expression and mRNA stability of activated CD4-positive T cells in patients with systemic lupus erythematosus

References

• Mohan C, Shi Y, Laman JD, Datta SK. Interaction between CD40 and its ligand gp39 in the development of murine lupus nephritis. J Immunol 1995;154:1470–80.
   PubMed Web of Science ®Google Scholar
• Crow MK, Kirou KA. Regulation of CD40 ligand expression in systemic lupus erythematosus. Curr Opin Rheumatol 2001;13:361–9.
   PubMed Web of Science ®Google Scholar
• Kooten VC, Banchereau J. CD4O-CD40 ligand. J Leukoc Biol 2000;67:2–17.
   PubMedGoogle Scholar
• Santos-Argumedo L, Alvarez-Maya I, Romero-Ramirez H, Flores-Romo L. Enforced and prolonged CD40 ligand expression triggers autoantibody production in vivo. Eur J Immunol 2001;31: 3484–92.
   PubMed Web of Science ®Google Scholar
• Koshy M, Berger D, Crow MK. Increased expression of CD40 ligand on systemic lupus erythematosus lymphocytes. J Clin Invest 1996;98: 826–37.
   Google Scholar
• Desai-Mehta A, Lu L, Ramsey-Goldman R, Datta SK. Hyperexpression of CD40 ligand by B and T cells in human lupus and its role in pathogenic autoantibody production. J Clin Invest 1996;97: 2063–73.
   Google Scholar
• Yellin MJ, D'Agati V, Parkinson G, Han AS, Szema A, Baum D, et al. Immunohistologic analysis of renal CD40 and CD4OL expres-sion in lupus nephritis and other glomerulonephritides. Arthritis Rheum 1997;40:124–34.
   PubMedGoogle Scholar
• Yellin MJ, Sippel K, Inghirami G, Covey LR, Lee JJ, Sinning J, et al. CD40 molecules induce down-modulation and endocytosis of T cell surface T cell-B cell activating molecule/CD4O-L. Potential role in regulating helper effector function. J Immunol 1994;15; 152:598–608.
   Google Scholar
• Graf D, Muller S, Korthauer U, van Kooten C, Weise C, Kroczek RA. A soluble form of TRAP (CD40 ligand) is rapidly released after T cell activation. Eur J Immunol 1995;25: 1749–54.
   Google Scholar
• Kato K, Santana-Sahagun E, Rassenti LZ, Weisman MH, Tamura N, Kobayashi S, et al. The soluble CD40 ligand sCD154 in systemic lupus erythematosus. J Clin Invest 1999;104:947–55.
   PubMed Web of Science ®Google Scholar
• Ford GS, Barnhart B, Shone S, Covey LR. Regulation of CD154 (CD40 ligand) mRNA stability during T cell activation. J Immunol 1999;162:4037–44.
   PubMed Web of Science ®Google Scholar
• Suarez A, Mozo L, Gayo A, Zamorano J, Gutierrez C. Require-ment of a second signal via protein kinase C or protein kinase A for maximal expression of CD40 ligand. Involvement of transcrip-tional and posttranscriptional mechanisms. Eur J Immunol 1997; 27:2822–9.
   Google Scholar
• Shaw G, Kamen R. A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell 1986;46:659–67.
   PubMed Web of Science ®Google Scholar
• Dean JL, Wait R, Mahtani KR, Sully G, Clark AR, Saklatvala J. The 3' untranslated region of tumor necrosis factor alpha mRNA is a target of the mRNA-stabilizing factor HuR. Mol Cell Biol 2001; 21:721–30.
   PubMed Web of Science ®Google Scholar
• Rigby WF, Waugh MG, Hamilton BJ. Characterization of RNA binding proteins associated with CD40 ligand (CD154) mRNA turnover in human T lymphocytes. J Immunol 1999;163: 4199–206.
   Google Scholar
• Barnhart B, Kosinski PA, Wang Z, Ford GS, Kiledjian M, Covey LR. Identification of a complex that binds to the CD154 3' untranslated region: implications for a role in message stability during T cell activation. J Immunol 2000;165:4478–86.
   PubMed Web of Science ®Google Scholar
• Tan EM, Cohen AS, Fries JF, Masi AT, McShane DJ, Rothfield NF, et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982;25:1271–7.
   PubMed Web of Science ®Google Scholar
• Bombardier C, Gladman D, Urowitz MB, Caron D, Chang CH, and the Committee on Prognosis Studies in SLE. Derivation of the SLEDAI: a disease activity index for lupus patients. Arthritis Rheum 1992;35:630–40.
   PubMed Web of Science ®Google Scholar
• Mach F, Schonbeck U, Sukhova GK, Bourcier T, Bonnefoy JY, Pober JS, et al. Functional CD40 ligand is expressed on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for CD4O-CD40 ligand signaling in atherosclerosis. Proc Natl Acad Sci USA 1997;94:1931–6.
   PubMed Web of Science ®Google Scholar
• Powell MJ, Thompson SA, Tone Y, Waldmann H, Tone M. Post-transcriptional regulation of IL-10 gene expression through se-quences in the 3'-untranslated region. J Immunol 2000;165: 292–6.
   Google Scholar
• Esnault S, Jarzembowski JA, Matter JS. Stabilization of granulo-cyte-macrophage colony-stimulating factor RNA in a human eosi-nophil-like cell line requires the AUUUA motifs. Proc Assoc Am Physicians 1998;110:575–84.
   Google Scholar
• Kim YU, Rus HG, Fisher SN, Pitha PM, Shin ML. Binding of a protein to an AU-rich domain of tumour necrosis factor alphamFtNA as a 35-kDa complex and its regulation in primary ratastrocytes. Biochem J 1996;316: 455–60.
   Google Scholar
• Gaffney PM, Kearns GM, Shark KB, Ortmann WA, Selby SA, Malmgren ML, et al. A genome-wide search for susceptibility genes in human systemic lupus erythematosus sib-pair families. Proc Natl Acad Sci USA 1998;95:14875–9.
   PubMed Web of Science ®Google Scholar
• Wu J, Edberg JC, Gibson AW, Tsao B, Kimberly RP. Single-nucleotide polymorphisms of T cell receptor chain in patients with systemic lupus erythematosus. Arthritis Rheum 1999;42:2601–5.
   Google Scholar
• Liossis SN, Ding XZ, Dennis GJ, Tsokos GC. Altered pattern of TCR/CD3-mediated protein-tyrosyl phosphorylation in T cells from patients with systemic lupus erythematosus. Deficient expres-sion of the T cell receptor chain. J Clin Invest 1998;101:1448–57.
   PubMed Web of Science ®Google Scholar
• Tsukada K, Onoda N, Yoshimoto K, Setoyama Y, Suzuki K, PangM, et al. T-cell receptor mFtNA with an alternatively spliced 3' untranslated region is generated predominantly in the peripheral blood T cells of systemic lupus erythematosus patients. Mod Ftheumatol 2002;12:167–73.
   PubMedGoogle Scholar
• Hishikawa T, Tokano Y, Sekigawa I, Ando S, Takasaki Y, Hashimoto H, et al. HLA-DP+ T cells and deficient interleukin-2 production in patients with systemic lupus erythematosus. Chin Immunol Immunopathol 1990;55:285–96.
   PubMedGoogle Scholar
• Skov S, Bonyhadi M, Odum N, Ledbetter JA. IL-2 and IL-15 regulate CD154 expression on activated CD4 T cells. J Immunol 2000;164:3500–5.
   PubMed Web of Science ®Google Scholar
• Aringer M, Stummvoll GH, Steiner G, Koller M, Steiner CW, Holler E, et al. Serum interleukin-15 is elevated in systemic lupus erythematosus. Ftheumatology (Oxford) 2001;40:876–81.
   PubMed Web of Science ®Google Scholar
• Wong CK, Ho CY, Li EK, Lam CW. Elevation of proinflammatory cytokine (IL-18, IL-17, IL-12) and Th2 cytokine (IL-4) concentra-tions in patients with systemic lupus erythematosus. Lupus 2000;9: 589–93.
   PubMed Web of Science ®Google Scholar
• Nanki T, Lipsky PE. Cutting edge: stromal cell-derived factor-1 is a costimulator for CD4+ T cell activation. J Immunol 2000;164: 5010–4.
   PubMed Web of Science ®Google Scholar
• O'Regan AW, Hayden JM, Berman JS. Osteopontin augments CD3-mediated interferon-gamma and CD40 ligand expression by T cells, which results in IL-12 production from peripheral blood mononuclear cells. J Leukoc Biol 2000;68:495–502.
   PubMed Web of Science ®Google Scholar
• Tsytsykova AV, Tsitsikov EN, Geha RS. The CD4OL promoter contains nuclear factor of activated T cell-binding motifs which require AP-1 binding for activation of transcription. J Biol Chem 1996;271: 3763–70.
   Google Scholar
• Schubert LA, King G, Cron RQ, Lewis DB, Aruffo A, Hollenbaugh D. The human gp39 promoter. Two distinct nuclear factors of activated T cell protein-binding elements contribute in-dependently to transcriptional activation. J Biol Chem 1995;270: 29624–7.
   Google Scholar
• Fields PE, Gajewski TF, Fitch FW. Blocked p21 Ras activation in anergic CD4+ T cells. Science 1996;271: 1276–8.
   Google Scholar
• Vassilopoulos D, Kovacs B, Tsolos GC. TCR/CD3 complex-mediated signal transduction pathway in T cells and T cell lines from patients with systemic lupus erythematosus. J Immunol 1995;129: 2269–81.
   Google Scholar
• Fuleihan R, Ramesh N, Homer A, Ahern D, Belshaw PJ, Alberg DG, et al. Cyclosporin A inhibits CD40 ligand expression in T lymphocytes. J Clin Invest 1994;93:1315–20.
   PubMed Web of Science ®Google Scholar
• Yi Y, McNerney M, Datta SK. Regulatory defects in Cbl and mitogen-activated protein kinase (extracellular signal-related kinase) pathways cause persistent hyperexpression of CD40 ligand in human lupus T cells. J Immunol 2000;165: 6627–34.
   Google Scholar
• Murakami K, Ma W, Fuleihan R, Pober JS. Human endothelial cells augment early CD40 ligand expression in activated CD4+ T cells through LFA-3-mediated stabilization of mRNA. J Immunol 1999;163:2667–73.
   PubMed Web of Science ®Google Scholar
• Larche M, Till SJ, Haselden BM, North J, Barkans J, Corrigan CJ, et al. Costimulation through CD86 is involved in airway antigen-presenting cell and T cell responses to allergen in atopic asthmat-ics. J Immunol 1998;161:6375–82.
   PubMed Web of Science ®Google Scholar
• McAdam AJ, Greenwald RJ, Levin MA, Chernova T, Malenkovich N, Ling V, et al. ICOS is critical for CD40-mediated antibody class switching. Nature 2001;409:102–5.
   PubMed Web of Science ®Google Scholar
• Parra E, Mustelin T, Dohlsten M, Mercola D. Identification of a CD28 response element in the CD40 ligand promoter. J Immunol 2001;166:2437–43.
   PubMed Web of Science ®Google Scholar
• Li W, Whaley CD, Mondino A, Mueller DL. Blocked signal trans-duction to the ERK and JNK protein kinases in anergic CD4+ T cells. Science 1996;271:1272–6.
   PubMed Web of Science ®Google Scholar