21
Views
10
CrossRef citations to date
0
Altmetric
CASE REPORT

Increased serum interleukin-18 in a patient with systemic lupus erythematosus and T-cell large granular lymphocytic leukemia

, , , &
Pages 267-270 | Received 29 Sep 2003, Accepted 01 Mar 2004, Published online: 02 Jan 2014

References

  • Loughran TP Jr. Clonal diseases of large granular lymphocytes. Blood 1993;82:1–14.
  • Lima M, Almeida J, Dos Anjos Teixeira M, Alguero Md Mdel C, Santos AH, Balanzategui A, et al. TCRalphabeta+/CD4+ large granular lymphocytosis: a new clonal T-cell lymphoproliferative disorder. Am J Pathol 2003;163: 763–71.
  • Bowman SJ, Sivakumaran M, Snowden N, Bhavnani M, Hall MA, Panayi GS, et al. The large granular lymphocyte syndrome with rheumatoid arthritis. Immunogenetic evidence for a broader definition of Felty's syndrome. Arthritis Rheum 1994;37:1326–30.
  • Hoshino T, Kawase Y, Okamoto M, Yokota K, Yoshino K, Yamamura K, et al. IL-18-transgenic mice: in vivo evidence of a broad role for IL-18 in modulating immune function. J Immunol 2001;166:7014–8.
  • Bresnihan B, Roux-Lombard P, Murphy E, Kane D, FitzGerald 0, Dayer JM. Serum interleukin 18 and interleukin 18 binding protein in rheumatoid arthritis. Ann Rheum Dis 2002;61: 726–9.
  • Kawashima M, Yamamura M, Taniai M, Yamauchi H, Tanimoto T, Kurimoto M, et al. Levels of interleukin-18 and its binding inhibitors in the blood circulation of patients with adult-onset Still's disease. Arthritis Rheum 2001;44:550–60.
  • Wong CK, Li EK, Ho CY, Lam CW. Elevation of plasma interleukin-18 concentration is correlated with disease activity in systemic lupus erythematosus. Ftheumatology (Oxford) 2000;39: 1078–81.
  • Neumann D, Del Giudice E, Ciaramella A, Boraschi D, Bossu P. Lymphocytes from autoimmune MRL lpr/lpr mice are hyper-responsive to IL-18 and overexpress the IL-18 receptor accessory chain. J Immunol 2001;166:3757–62.
  • Kothapalli R, Bailey RD, Kusmartseva I, Mane S, Epling-Burnette PK, Loughran TP Jr. Constitutive expression of cytotoxic proteases and down-regulation of protease inhibitors in LGL leukemia. Int J Oncol 2003;22:33–9.
  • Dang NH, Aytac U, Sato K, O'Brien S, Melenhorst J, Morimoto C, et al. T-large granular lymphocyte lymphoproliferative disorder: expression of CD26 as a marker of clinically aggressive disease and characterization of marrow inhibition. Br J Haematol 2003;121: 857–65.
  • Baker BL, Hendricks JB, Shahidi NT, Woodson RD, Schultz JC, Norback DH. Humoral and cellular immunosuppression of granu-lopoiesis in a patient with neutropenia. Am J Med 1988;85:264–8.
  • Reynolds CW, Foon KA. T-lymphoproliferative disease and re-lated disorders in human and experimental animals: a review of the clinical, cellular, and functional characteristics. Blood 1984;64: 1146–58.
  • Akashi K, Shibuya T, Taniguchi S, Hayashi S, Iwasaki H, Teshima T, et al. Multiple autoimmune haemopoietic disorders and insidi-ous clonal proliferation of large granular lymphocytes. Br J Haematol 1999;107:670–3.
  • Orman SV, Schechter GP, Whang-Peng J, Guccion J, Chan C, Schulof RS, et al. Nephrotic syndrome associated with a clonal T-cell leukemia of large granular lymphocytes with cytotoxic function. Arch Intern Med 1986;146:1827–9.
  • Sottini A, Bettinardi A, Quiros-Roldan E, Plebani A, Afro P, Primi D, et al. Evidence for antigenic selection of large granular lympho-cytes in a patient with Wiskott-Aldrich syndrome. Blood 1995;86: 2240–7.
  • Camagna A, Cedrone L, Care A, Samoggia P, De Marco MC, Del Duca P, et al. Polyclonal expansion of CD3(+)/CD4(+)/CD56(+) large granular lymphocytes and autoimmunity associated with dysregulation of Fas/FasL apoptotic pathway. Br J Haematol 2001;112:204–7.
  • Lamy T, Liu JH, Landowski TH, Dalton WS, Loughran TP Jr. Dysregulation of CD95/CD95 ligand-apoptotic pathway in CD3(+) large granular lymphocyte leukemia. Blood 1998;92:4771–7.
  • Watanabe-Fukunaga R, Brannan CI, Copeland NG, Jenkins NA, Nagata S. Lymphoproliferation disorder in mice explained by de-fects in Fas antigen that mediates apoptosis. Nature 1992;356:314–7.
  • Takahashi T, Tanaka M, Brannan CI, Jenkins NA, Copeland NG, Suda T, et al. Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell 1994;76:969–76.
  • Sneller MC, Wang J, Dale JK, Strober W, Middelton LA, Choi Y, et al. Clinical, immunologic, and genetic features of an auto-immune lymphoproliferative syndrome associated with abnormal lymphocyte apoptosis. Blood 1997;89:1341–8.
  • Esfandiari E, McInnes IB, Lindop G, Huang FP, Field M, Komai-Koma M, et al. A proinflammatory role of IL-18 in the develop-ment of spontaneous autoimmune disease. J Immunol 2001;167: 5338–47.
  • Bossu P, Neumann D, Del Giudice E, Ciaramella A, Gloaguen I, Fantuzzi G, et al. IL-18 cDNA vaccination protects mice from spontaneous lupus-like autoimmune disease. Proc Natl Acad Sci USA 2003;100:14181–6.
  • Akahoshi M, Nakashima H, Tanaka Y, Kohsaka T, Nagano S, Ohgami E, et al. Th1/Th2 balance of peripheral T helper cells in systemic lupus erythematosus. Arthritis Rheum 1999;42:1644–8.
  • Amerio P, Frezzolini A, Abeni D, Teofoli P, Girardelli CR, De Pita 0, et al. Increased IL-18 in patients with systemic lupus erythematosus: relations with Th-1, Th-2, pro-inflammatory cytokines and disease activity. IL-18 is a marker of disease activity but does not correlate with pro-inflammatory cytokines. Clin Exp Ftheumatol 2002;20: 535–8.
  • Masutani K, Akahoshi M, Tsuruya K, Tokumoto M, Ninomiya T, Kohsaka T, et al. Predominance of Thl immune response in diffuse proliferative lupus nephritis. Arthritis Rheum 2001;44: 2097–106.
  • Zeng D, Liu Y, Sidobre S, Kronenberg M, Strober S. Activation of natural killer T cells in NZB/W mice induces Thl-type immune responses exacerbating lupus. J Clin Invest 2003;112:1211–22.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.